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by Peloso, Gina M and Auer, Paul L and Bis, Joshua C and Voorman, Arend and Morrison, Alanna C and Stitziel, Nathan O and Brody, Jennifer A and Khetarpal, Sumeet A and Crosby, Jacy R and Fornage, Myriam and Isaacs, Aaron and Jakobsdottir, Johanna and Feitosa, Mary F and Davies, Gail and Huffman, Jennifer E and Manichaikul, Ani and Davis, Brian and Lohman, Kurt and Joon, Aron Y and Smith, Albert V and Grove, Megan L and Zanoni, Paolo and Redon, Valeska and Demissie, Serkalem and Lawson, Kim and Peters, Ulrike and Carlson, Christopher and Jackson, Rebecca D and Ryckman, Kelli K and Mackey, Rachel H and Robinson, Jennifer G and Siscovick, David S and Schreiner, Pamela J and Mychaleckyj, Josyf C and Pankow, James S and Hofman, Albert and Uitterlinden, Andre G and Harris, Tamara B and Taylor, Herman A and Taylor, Kent D and Stafford, Jeanette M and Reynolds, Lindsay M and Marioni, Riccardo E and Dehghan, Abbas and Franco, Oscar H and Patel, Aniruddh P and Lu, Yingchang and Hindy, George and Gottesman, Omri and Bottinger, Erwin P and Melander, Olle and Orho-Melander, Marju and Loos, Ruth J.F and Duga, Stefano and Merlini, Piera Angelica and Farrall, Martin and Goel, Anuj and Asselta, Rosanna and Girelli, Domenico and Martinelli, Nicola and Shah, Svati H and Kraus, William E and Li, Mingyao and Rader, Daniel J and Reilly, Muredach P and McPherson, Ruth and Watkins, Hugh and Ardissino, Diego and Zhang, Qunyuan and Wang, Judy and Tsai, Michael Y and Correa, Adolfo and Griswold, Michael E and Lange, Leslie A and Starr, John M and Rudan, Igor and Eiriksdottir, Gudny and Launer, Lenore J and Ordovas, Jose M and Levy, Daniel and Chen, Y.-D. Ida and Reiner, Alexander P and Hayward, Caroline and Polasek, Ozren and Deary, Ian J and Borecki, Ingrid B and Liu, Yongmei and Gudnason, Vilmundur and Wilson, James G and van Duijn, Cornelia M and Kooperberg, Charles and Rich, Stephen S and Psaty, Bruce M and Rotter, Jerome I and O’Donnell, Christopher J and Rice, Kenneth and Boerwinkle, Eric and Kathiresan, Sekar and Cupples, L. Adrienne and NHLBI GO Exome Sequencing Project and Diabetes - Cardiovascular Disease and Diabetes - kardiovaskulär sjukdom and Kardiovaskulär forskning - hypertoni and Cardiovascular Research - Hypertension and Lund University and EpiHealth: Epidemiology for Health and Lunds universitet and EXODIAB: Excellence in Diabetes Research in Sweden
The American Journal of Human Genetics, ISSN 0002-9297, 02/2014, Volume 94, Issue 2, pp. 223 - 232
Journal Article
Nature, ISSN 0028-0836, 04/2017, Volume 544, Issue 7649, pp. 235 - 239
Journal Article
Nature Neuroscience, ISSN 1097-6256, 05/2010, Volume 13, Issue 5, pp. 551 - 558
Brain structure and size require precise division of neural stem cells (NSCs), which self-renew and generate intermediate neural progenitors (INPs) and... 
HUMAN-CHROMOSOMES | PROTEIN | LIS1 EXPRESSION | LISSENCEPHALY GENE | SECKEL-SYNDROME | NASHI | SPINDLE ORIENTATION | NEUROGENESIS | NEUROSCIENCES | MESSENGER-RNA LOCALIZATION | CEREBRAL CORTICAL SIZE | Brain - embryology | Microcephaly - genetics | Embryo, Mammalian | Homeodomain Proteins - metabolism | Humans | Apoptosis - genetics | Green Fluorescent Proteins - genetics | RNA, Messenger - metabolism | Neurogenesis - genetics | DNA Mutational Analysis | Organ Size - genetics | Repressor Proteins - metabolism | Animals, Newborn | Oligonucleotide Array Sequence Analysis - methods | Repressor Proteins - genetics | Genotype | Mice, Transgenic | In Situ Nick-End Labeling - methods | Mutation - genetics | T-Box Domain Proteins - metabolism | Eye Proteins - metabolism | Brain - pathology | Mice | HeLa Cells | Paired Box Transcription Factors - genetics | Neurons - pathology | Age Factors | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Gene Expression Regulation, Developmental - genetics | Brain - growth & development | Cell Differentiation - genetics | 1-Alkyl-2-acetylglycerophosphocholine Esterase - genetics | Transfection | Microcephaly - pathology | Microcephaly - physiopathology | Bromodeoxyuridine - metabolism | Eye Proteins - genetics | Nuclear Proteins - genetics | RNA Interference - physiology | Cell Division - genetics | Mice, Inbred C57BL | Gene Expression Profiling - methods | Nuclear Proteins - metabolism | PAX6 Transcription Factor | Nerve Tissue Proteins - genetics | T-Box Domain Proteins - genetics | Homeodomain Proteins - genetics | Nerve Tissue Proteins - metabolism | 1-Alkyl-2-acetylglycerophosphocholine Esterase - metabolism | Animals | Stem Cells - physiology | Paired Box Transcription Factors - metabolism | Animal experimentation | Axons | Usage | Brain research | Cell division | Physiological aspects | Causes of | Research | Microcephaly | Mental retardation | Risk factors
Journal Article
Cell Metabolism, ISSN 1550-4131, 05/2012, Volume 15, Issue 5, pp. 665 - 674
Nonalcoholic fatty liver disease (NAFLD) is associated with increased cardiovascular and liver-related mortality. NAFLD is characterized by both triglyceride... 
RAT-LIVER | RISK-FACTORS | MACROPHAGE APOPTOSIS | PROTEIN-KINASE | ENDOCRINOLOGY & METABOLISM | HMG-COA REDUCTASE | STEATOHEPATITIS | 3-HYDROXY-3-METHYLGLUTARYL COENZYME | PREVALENCE | MICRORNA EXPRESSION | MODULATION | CELL BIOLOGY | Sirtuin 1 - metabolism | Up-Regulation | Cholesterol - blood | Humans | Middle Aged | Sterol Esterase - metabolism | Male | MicroRNAs - metabolism | Desmosterol - metabolism | Cardiovascular Diseases - genetics | Cholesterol - genetics | Sirtuin 1 - genetics | Case-Control Studies | Phosphorylation - genetics | Hydroxymethylglutaryl CoA Reductases - metabolism | Adenylate Kinase - metabolism | Non-alcoholic Fatty Liver Disease | Sterol O-Acyltransferase - metabolism | Adult | Female | Lipid Metabolism - genetics | Sterol Regulatory Element Binding Protein 2 - genetics | Sterol Regulatory Element Binding Protein 2 - metabolism | Fatty Liver - genetics | Receptors, LDL - genetics | Gene Expression | Fatty Liver - metabolism | Cardiovascular Diseases - metabolism | Fatty Liver - blood | Liver - metabolism | Receptors, LDL - metabolism | Cholesterol - metabolism | Cholesterol, LDL - genetics | Phenotype | Sterol Esterase - genetics | Desmosterol - blood | Cholesterol, LDL - metabolism | MicroRNAs - genetics | Sterol O-Acyltransferase - genetics | Adenylate Kinase - genetics | Hydroxymethylglutaryl CoA Reductases - genetics | Enzymes | Liver diseases | Low density lipoproteins | Genes | Esters | Triglycerides | Cholesterol | MicroRNA | Fatty liver | Blood cholesterol | Physiological aspects | Hydrolases | Blood lipids | Health aspects | Statins | atherosclerosis | Nonalcoholic steatohepatitis | cholesterol | Nonalcoholic fatty liver disease | fatty liver | lipogenesis | hypercholesterolemia | HMG CoA reductase
Journal Article
PLoS Genetics, ISSN 1553-7390, 11/2009, Volume 5, Issue 11, pp. e1000735 - e1000735
Journal Article
Current Neurology and Neuroscience Reports, ISSN 1528-4042, 4/2011, Volume 11, Issue 2, pp. 171 - 178
Cortical malformations associated with defects in neuronal migration result in severe developmental consequences including intractable epilepsy and... 
Subcortical band heterotopia | ARX | Polymicrogyria | Pachygyria | Periventricular nodular heterotopia | Neurology | Neuronal migration | Cobblestone lissencephaly | FilaminA | Miller-Dieker syndrome | Reelin | Medicine & Public Health | Lissencephaly | Doublecortin | FILAMIN-A MUTATIONS | MENTAL-RETARDATION | NEUROSCIENCES | CEREBRAL-CORTEX | CLINICAL NEUROLOGY | DOUBLE CORTEX SYNDROME | PERIVENTRICULAR HETEROTOPIA | MICE | CEREBELLAR HYPOPLASIA | Contractile Proteins - genetics | Malformations of Cortical Development, Group II - pathology | Microtubule-Associated Proteins - genetics | Molecular Biology | Humans | Neurons - cytology | Tubulin - genetics | Neural Stem Cells - cytology | Cerebral Cortex - cytology | Cell Movement - physiology | Microtubules - metabolism | Tubulin - metabolism | 1-Alkyl-2-acetylglycerophosphocholine Esterase - genetics | Neurons - physiology | Serine Endopeptidases - genetics | Neuropeptides - genetics | Cerebral Cortex - abnormalities | Microfilament Proteins - genetics | Receptors, LDL - genetics | Guanine Nucleotide Exchange Factors - genetics | Extracellular Matrix Proteins - genetics | Neural Stem Cells - physiology | Transcription Factors - genetics | Malformations of Cortical Development, Group II - genetics | Nerve Tissue Proteins - genetics | Cell Adhesion Molecules, Neuronal - genetics | Homeodomain Proteins - genetics | Syndrome | Filamins | Animals | Cerebral Cortex - embryology | Cerebral Cortex - growth & development | Mutation | Nervous system diseases | Care and treatment | Molecular genetics | Neurons | Genetic aspects | Research | Cell migration
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 2001, Volume 69, Issue 5, pp. 1002 - 1012
Journal Article
Brain, ISSN 0006-8950, 2014, Volume 137, Issue 1, pp. 69 - 77
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 10/2017, Volume 70, Issue 14, pp. 1732 - 1740
Genetic screening programs in unselected individuals with increased levels of low-density lipoprotein cholesterol (LDL-C) have shown modest results in... 
Dutch Lipid Clinic | cholesterol | genetics | low-density lipoprotein cholesterol | Simon Broome criteria | DIAGNOSIS | CARDIAC & CARDIOVASCULAR SYSTEMS | MANAGEMENT | MYOCARDIAL-INFARCTION | GUIDELINES | RISK | PREVALENCE | DENSITY-LIPOPROTEIN CHOLESTEROL | GENERAL-POPULATION | CARDIOVASCULAR-DISEASE | MUTATIONS | Risk Assessment - methods | Prevalence | Prognosis | Humans | Middle Aged | Hyperlipoproteinemia Type II - diagnosis | Male | Genetic Testing - methods | Patient Selection | Cholesterol, LDL - blood | Female | Hyperlipoproteinemia Type II - drug therapy | Multifactorial Inheritance - genetics | Receptors, LDL - genetics | Reproducibility of Results | Acute Coronary Syndrome - epidemiology | Comorbidity | Risk Factors | Proprotein Convertase 9 - genetics | Apolipoprotein B-100 - genetics | Sterol Esterase - genetics | Hyperlipoproteinemia Type II - epidemiology | Spain - epidemiology | Apolipoproteins E - genetics | Acute Coronary Syndrome - diagnosis | Adaptor Proteins, Signal Transducing - genetics | Hypolipidemic Agents - therapeutic use | Acute Coronary Syndrome - prevention & control | Hyperlipoproteinemia Type II - genetics | Care and treatment | Genetic aspects | Hypercholesterolemia | Coronary heart disease | Cardiac patients | Low density lipoproteins | Analysis | Medical genetics | Medical screening | Lipoproteins (low density) | Test procedures | Criteria | Patients | Low density lipoprotein | Cholesterol | Genetic screening | Disease prevention | Algorithms | Apolipoprotein E | Lipoprotein (low density) receptors | Diagnostic systems | Health risk assessment | Acute coronary syndromes | Statins
Journal Article