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British Journal of Clinical Pharmacology, ISSN 0306-5251, 08/2012, Volume 74, Issue 2, pp. 336 - 345
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • In healthy subjects, GSK2248761 was shown to be safe and well tolerated with single doses up to 1200 mg once daily... 
NNRTI | HIV‐1 infection | antiretroviral therapy | drug‐drug interaction | HIV-1 infection | Drug-drug interaction | Antiretroviral therapy | PHARMACOKINETICS | TOLERABILITY | PHARMACOLOGY & PHARMACY | ATAZANAVIR | SIMVASTATIN | drug-drug interaction | PROTEASE INHIBITORS | Fluorobenzenes - pharmacokinetics | Pyrroles - pharmacokinetics | Darunavir | Ethinyl Estradiol - pharmacokinetics | Humans | Pyrrolidinones - pharmacokinetics | Male | Fluorobenzenes - administration & dosage | Indoles - administration & dosage | Lopinavir - pharmacokinetics | Anti-HIV Agents - administration & dosage | Pyrrolidinones - administration & dosage | Tenofovir | Deoxycytidine - pharmacokinetics | Drug Interactions | Pyrroles - administration & dosage | Contraceptives, Oral - administration & dosage | Patient Safety | Atazanavir Sulfate | Contraceptives, Oral - pharmacokinetics | Phosphinic Acids - administration & dosage | Raltegravir Potassium | Emtricitabine | Adenine - analogs & derivatives | Pyridines - administration & dosage | Risk Assessment | Simvastatin - administration & dosage | Deoxycytidine - administration & dosage | Phosphinic Acids - pharmacokinetics | Rosuvastatin Calcium | Adenine - pharmacokinetics | Sulfonamides - pharmacokinetics | Cross-Over Studies | Cytochrome P-450 CYP3A - metabolism | Atorvastatin | Cytochrome P-450 CYP2D6 - metabolism | Least-Squares Analysis | Lopinavir - administration & dosage | Pyrimidines - pharmacokinetics | Oligopeptides - administration & dosage | Deoxycytidine - analogs & derivatives | Sulfonamides - administration & dosage | Cytochrome P-450 CYP2D6 Inhibitors | Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage | Heptanoic Acids - pharmacokinetics | Pyridines - pharmacokinetics | Reverse Transcriptase Inhibitors - administration & dosage | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacokinetics | Reverse Transcriptase Inhibitors - pharmacokinetics | Heptanoic Acids - administration & dosage | Female | Ethinyl Estradiol - administration & dosage | Androstenes - pharmacokinetics | Double-Blind Method | Ritonavir - administration & dosage | Pyrimidines - administration & dosage | Oligopeptides - pharmacokinetics | Linear Models | Simvastatin - pharmacokinetics | Androstenes - administration & dosage | Adenine - administration & dosage | Organophosphonates - pharmacokinetics | Organophosphonates - administration & dosage | Cytochrome P-450 CYP3A Inhibitors | Ritonavir - pharmacokinetics | Anti-HIV Agents - pharmacokinetics | Indoles - pharmacokinetics | Drug Combinations | Urine | Simvastatin | Drug interactions | Cytochrome P-450 | HIV (Viruses) | Complications and side effects | Analysis | Electrocardiogram | Electrocardiography | DNA polymerases | Ethinyl estradiol | Dosage and administration | Index Medicus | EKG | Antiviral agents | Urinalysis | Ritonavir | tenofovir | Cytochrome P450 | Lopinavir | ethinylestradiol | Blood | Infection | non-nucleoside reverse transcriptase inhibitors | Antiviral activity | Drug interaction | Probes | CYP2D6 protein
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 09/2006, Volume 80, Issue 3, pp. 203 - 215
Objectives: A volunteer trial was performed to compare the pharmacokinetics of 5 drugs-warfarin, ZK253 (Schering), diazepam, midazolam, and erythromycin-when... 
METABOLISM | WARFARIN | ERYTHROMYCIN | PHARMACOLOGY & PHARMACY | PHARMACODYNAMICS | MACROLIDE ANTIBIOTICS | ABSORPTION | PATHOPHYSIOLOGICAL STATES | ACCELERATOR MASS-SPECTROMETRY | BIOAVAILABILITY | DISPOSITION | Estradiol - blood | Estradiol - analogs & derivatives | Injections, Intravenous | Anticoagulants - administration & dosage | Area Under Curve | Humans | Middle Aged | GABA Modulators - pharmacokinetics | Midazolam - administration & dosage | Male | Drug Monitoring - methods | Warfarin - administration & dosage | Diazepam - pharmacokinetics | Dose-Response Relationship, Drug | Aged, 80 and over | Adult | Female | Administration, Oral | Diazepam - administration & dosage | Estradiol - administration & dosage | GABA Modulators - administration & dosage | GABA Modulators - blood | Midazolam - pharmacokinetics | Anticoagulants - blood | Erythromycin - administration & dosage | Warfarin - pharmacokinetics | Cross-Over Studies | Erythromycin - blood | Estradiol - pharmacokinetics | Erythromycin - pharmacokinetics | Midazolam - blood | Warfarin - blood | Adolescent | Diazepam - blood | Aged | Anticoagulants - pharmacokinetics | Chromatography, Liquid - methods | Mass Spectrometry - methods | Carbon Radioisotopes | Warfarin | Dosage and administration | Erythromycin | Health aspects | Diazepam | Index Medicus | Abridged Index Medicus
Journal Article
JAMA, ISSN 0098-7484, 11/2002, Volume 288, Issue 18, pp. 2282 - 2292
Journal Article
Journal Article
Tumori, ISSN 0300-8916, 01/2015, Volume 101, Issue 1, pp. 30 - 35
Background: Elderly patients with metastatic breast cancer (MBC) have more problems receiving chemotherapy than younger patients, especially with the presence... 
Metastatic breast cancer | FACT-B test | Metronomic therapy | Elderly patients | Vinorelbine | Quality of life | TRIAL | ONCOLOGY | CHEMOTHERAPY | Triazoles - administration & dosage | Estradiol - analogs & derivatives | Administration, Metronomic | Capecitabine | Humans | Receptors, Estrogen - analysis | Vinblastine - administration & dosage | Carcinoma, Ductal, Breast - chemistry | Nitriles - administration & dosage | Receptors, Progesterone - analysis | Antineoplastic Agents, Phytogenic - administration & dosage | Breast Neoplasms - chemistry | Carcinoma, Ductal, Breast - drug therapy | Anthracyclines - administration & dosage | Antibodies, Monoclonal, Humanized - administration & dosage | Fluorouracil - administration & dosage | Neoplasm Grading | Vinblastine - analogs & derivatives | Vinblastine - adverse effects | Aged, 80 and over | Carcinoma, Ductal, Breast - pathology | Female | Quinazolines - administration & dosage | Antineoplastic Agents, Phytogenic - adverse effects | Fluorouracil - analogs & derivatives | Administration, Oral | Biomarkers, Tumor - analysis | Deoxycytidine - administration & dosage | Estradiol - administration & dosage | Treatment Outcome | Breast Neoplasms - drug therapy | Taxoids - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Breast Neoplasms - pathology | Aged | Carcinoma, Lobular - drug therapy | Receptor, ErbB-2 - analysis | Neoplasm Staging | Deoxycytidine - analogs & derivatives | Trastuzumab
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 03/2016, Volume 374, Issue 13, pp. 1221 - 1231
Journal Article
Journal Article