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Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 02/2007, Volume 67, Issue 4, pp. 1626 - 1635
Cervical cancer is a leading cause of death due to cancer among women worldwide. Using transgenic mice to dissect the contributions of the human papillomavirus... 
UTERINE CERVIX | DIFFERENTIAL EXPRESSION | EPITHELIAL-CELLS | ONCOLOGY | UBIQUITIN-PROTEIN LIGASE | HUMAN SCRIBBLE | TYPE-16 E7 ONCOGENE | TUMOR-SUPPRESSOR PROTEIN | MEDIATED DEGRADATION | TRANSGENIC MOUSE MODEL | HUMAN HOMOLOG | Cell Cycle - genetics | Up-Regulation | Tumor Suppressor Protein p53 - biosynthesis | Skin - metabolism | Humans | Uterine Cervical Neoplasms - pathology | Minichromosome Maintenance Complex Component 7 | Oncogenes - physiology | Cyclin E - genetics | Tumor Suppressor Protein p53 - genetics | Retinoblastoma Protein - biosynthesis | Nuclear Proteins - biosynthesis | Uterine Cervical Neoplasms - chemically induced | Cell Cycle Proteins - genetics | Cyclin-Dependent Kinase Inhibitor p16 - biosynthesis | Female | Oncogene Proteins, Viral - genetics | Nuclear Proteins - genetics | Skin - virology | Estradiol - pharmacology | Repressor Proteins - metabolism | Oncogene Proteins, Viral - metabolism | Cyclin-Dependent Kinase Inhibitor p16 - genetics | Repressor Proteins - genetics | Mice, Transgenic | Cell Cycle Proteins - biosynthesis | DNA-Binding Proteins - genetics | Oncogene Proteins, Viral - biosynthesis | Cocarcinogenesis | Animals | Repressor Proteins - biosynthesis | Retinoblastoma Protein - genetics | Cyclin E - biosynthesis | Uterine Cervical Neoplasms - virology | Mice | DNA-Binding Proteins - biosynthesis | Index Medicus
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 01/2015, Volume 308, Issue 2, pp. L141 - L146
Supplemental oxygen, used to treat hypoxia in preterm and term neonates, increases the risk of neonatal lung diseases, such as bronchopulmonary dysplasia (BPD)... 
2-methoxy-estradiol | Neonate | Hyperoxia | CYP1a1 | Bronchopulmonary dysplasia | Airway smooth muscle | Estradiol | CELLS | PHYSIOLOGY | hyperoxia | MOUSE | airway smooth muscle | LUNG INJURY | PATTERNS | neonate | MODEL | bronchopulmonary dysplasia | RESPIRATORY SYSTEM | INFANTS | MICE | EXPRESSION | estradiol | Up-Regulation | Cell Hypoxia - physiology | Estradiol - analogs & derivatives | Receptors, Estrogen - metabolism | Cell Proliferation | Hyperoxia - physiopathology | Reactive Oxygen Species - metabolism | Humans | Cytochrome P-450 CYP1B1 - biosynthesis | Oxygen - metabolism | Bronchopulmonary Dysplasia - epidemiology | Estrogen Receptor beta - metabolism | RNA, Messenger - biosynthesis | Estrogen Receptor beta - genetics | Estrogen Receptor beta - biosynthesis | Estrogen Receptor alpha - metabolism | Lung - metabolism | Estradiol - biosynthesis | Asthma - epidemiology | Catechol O-Methyltransferase - biosynthesis | Estradiol - metabolism | Lung - pathology | Receptors, Estrogen - genetics | Cells, Cultured | Aromatase - biosynthesis | Muscle, Smooth - metabolism | Mice, Inbred ICR | Animals | Estrogen Receptor alpha - genetics | Sex Factors | Receptors, Estrogen - biosynthesis | Lung - embryology | Estrogen Receptor alpha - biosynthesis | Mice | Cytochrome P-450 CYP1A1 - biosynthesis | Apoptosis | Airways | Infants (Premature) | Physiological aspects | Smooth muscle | Metabolism | Health aspects | Risk factors | Oxygen | Lung diseases | Risk assessment | Rodents | Genes | Hypoxia | Index Medicus | Rapid Report | 2-methoxyestradiol
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 04/2002, Volume 94, Issue 8, pp. 606 - 616
Journal Article
Journal of Enzyme Inhibition and Medicinal Chemistry, ISSN 1475-6366, 01/2018, Volume 33, Issue 1, pp. 1271 - 1282
Ring A halogenated 13α-, 13β-, and 17-deoxy-13α-estrone derivatives were synthesised with N-halosuccinimides as electrophile triggers. Substitutions occurred... 
Estrone | STS | aromatase | 17β-HSD1 | halogenations | DESIGN | CHEMISTRY, MEDICINAL | 17-BETA-HYDROXYSTEROID DEHYDROGENASE | SPECIFICITY | ANALOGS | BIOCHEMISTRY & MOLECULAR BIOLOGY | STEROID SULFATASE INHIBITORS | BREAST-CANCER | IN-VITRO | PLACENTAL AROMATASE CYTOCHROME-P-450 | 17 beta-HSD1 | ESTRADIOL | BINDING | Index Medicus
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 01/2014, Volume 211, Issue 1, pp. 15 - 28
Lymphangioleiomyomatosis (LAM) is a progressive neoplastic disorder that leads to lung destruction and respiratory failure primarily in women. LAM is typically... 
MEDICINE, RESEARCH & EXPERIMENTAL | SIGNALING PATHWAYS | CYCLOOXYGENASE-2 | INHIBITION | TUBEROUS SCLEROSIS COMPLEX | GENE | PULMONARY LYMPHANGIOLEIOMYOMATOSIS | DISEASE | IMMUNOLOGY | MUTATIONAL ANALYSIS | CANCER | PROGRESSION | Index Medicus
Journal Article
Toxicological Sciences, ISSN 1096-6080, 2011, Volume 119, Issue 1, pp. 209 - 217
Journal Article
European Journal of Pharmaceutical Sciences, ISSN 0928-0987, 10/2018, Volume 123, pp. 404 - 415
Estrogen-induced intrahepatic cholestasis is one of the most common pathogenic factors for liver diseases in clinic. It is, however, regrettable that effective... 
Compensatory mechanism | 17α-Ethynylestradiol | Enzyme | Chenodeoxycholic acids | Ileum-liver Fxr signaling axis | Intrahepatic cholestasis | Transporter | FXR | ACTIVATION | STIMULATION | 17 alpha-Ethynylestradiol | SALT EXPORT PUMP | NUCLEAR RECEPTORS | TRANSPORT | METABOLISM | PHARMACOLOGY & PHARMACY | EXPRESSION | BILE-ACIDS | Steroid 12-alpha-Hydroxylase - metabolism | Up-Regulation | Ileum - pathology | Liver - pathology | Rats, Wistar | Humans | Ileum - metabolism | Male | Chenodeoxycholic Acid - biosynthesis | Disease Models, Animal | ATP Binding Cassette Transporter, Subfamily B, Member 11 - metabolism | Cell Line | Cholestasis, Intrahepatic - genetics | Signal Transduction | Cholestasis, Intrahepatic - chemically induced | Cholestasis, Intrahepatic - pathology | Liver - metabolism | Receptors, Cytoplasmic and Nuclear - genetics | Ethinyl Estradiol | Chenodeoxycholic Acid - analogs & derivatives | ATP Binding Cassette Transporter, Subfamily B, Member 11 - genetics | Cholesterol 7-alpha-Hydroxylase - genetics | Cholestasis, Intrahepatic - metabolism | Steroid 12-alpha-Hydroxylase - genetics | Animals | Cholestanetriol 26-Monooxygenase - genetics | Cholestanetriol 26-Monooxygenase - metabolism | Cholesterol 7-alpha-Hydroxylase - metabolism | Molecular Docking Simulation | Receptors, Cytoplasmic and Nuclear - metabolism | Index Medicus
Journal Article