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Journal of Neuroscience, ISSN 0270-6474, 01/2009, Volume 29, Issue 2, pp. 393 - 401
Glucocorticoids exert an opposing rapid regulation of glutamate and GABA synaptic inputs to hypothalamic magnocellular neurons via the activation of... 
GABA | Magnocellular neuron | Endocannabinoid | Glucocorticoid | Nitric oxide | SUPRAOPTIC NUCLEUS | endocannabinoid | glucocorticoid | nitric oxide | ACTIVATION | magnocellular neuron | NITRIC-OXIDE SYNTHASE | NEUROSCIENCES | MEMBRANE ESTROGEN-RECEPTORS | ENDOCANNABINOID RELEASE | PARAVENTRICULAR NUCLEUS | G(alpha) | ADRENALECTOMIZED RATS | NEURONS | VASOPRESSIN | OXYTOCIN | G(beta)gamma | Cannabinoid Receptor Modulators - metabolism | Synaptic Transmission - physiology | gamma-Aminobutyric Acid - metabolism | GTP-Binding Proteins - antagonists & inhibitors | Male | Penicillamine - analogs & derivatives | Patch-Clamp Techniques - methods | Quinoxalines - pharmacology | Dexamethasone - pharmacology | Piperidines - pharmacology | Dronabinol - analogs & derivatives | Neurons - physiology | Nitric Oxide Donors - pharmacology | Dronabinol - pharmacology | Neurons - drug effects | Electric Stimulation - methods | Pyrans - pharmacology | Guanosine Diphosphate - pharmacology | Pyrazoles - pharmacology | Cyclic AMP-Dependent Protein Kinases - metabolism | Synapses - drug effects | Synapses - physiology | Penicillamine - pharmacology | Valine - analogs & derivatives | Enzyme Inhibitors - pharmacology | Rats | Excitatory Amino Acid Antagonists - pharmacology | Thionucleotides - pharmacology | Rats, Sprague-Dawley | Animals | Guanosine Diphosphate - analogs & derivatives | Hypothalamus - cytology | Signal Transduction - drug effects | Arginine - pharmacology | Cannabinoid Receptor Modulators - antagonists & inhibitors | Glucocorticoids - pharmacology | Glutamic Acid - metabolism | Valine - pharmacology | In Vitro Techniques | Nitric Oxide - metabolism | GTP-Binding Proteins - metabolism | Gβγ |
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 10/2009, Volume 29, Issue 41, pp. 12982 - 12993
Estrogen, in addition to its genomic effects in brain, causes rapid and reversible changes to synaptic operations. We report here that these acute actions are... 
SPRAGUE-DAWLEY RATS | INDUCED INCREASE | DENDRITIC SPINE DENSITY | NEUROTROPHIC FACTOR | ACTIN POLYMERIZATION | HIPPOCAMPAL PYRAMIDAL NEURONS | LIM-KINASE | REPLACEMENT THERAPY | LONG-TERM POTENTIATION | NEUROSCIENCES | ESTROUS-CYCLE | Estradiol - analogs & derivatives | Synaptic Transmission - physiology | Age Factors | Rats, Long-Evans | Actins - metabolism | Neuronal Plasticity - drug effects | Estrogen Antagonists - pharmacology | Male | Neurons - cytology | Ginsenosides - pharmacology | Excitatory Postsynaptic Potentials - drug effects | Neural Pathways - physiology | Patch-Clamp Techniques - methods | Dose-Response Relationship, Drug | Excitatory Postsynaptic Potentials - physiology | Sapogenins - pharmacology | Neuronal Plasticity - physiology | Long-Term Potentiation - drug effects | Dendritic Spines - drug effects | Neurons - physiology | Female | Synaptic Transmission - drug effects | Estrogens - metabolism | Neurons - drug effects | Thiazolidines - pharmacology | Electric Stimulation - methods | Estradiol - pharmacology | Phenols - pharmacology | Animals, Newborn | Dendritic Spines - physiology | Rats | Excitatory Amino Acid Antagonists - pharmacology | Ovariectomy - methods | Biophysics | Hippocampus - cytology | Rats, Sprague-Dawley | GABA Antagonists - pharmacology | Microscopy, Confocal | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Animals | Analysis of Variance | Signal Transduction - drug effects | Cytoskeleton - metabolism | Picrotoxin - pharmacology | Oxazoles - pharmacology | In Vitro Techniques
Journal Article
Toxicology and applied pharmacology, ISSN 0041-008X, 2017, Volume 325, pp. 61 - 70
Estrogen receptors (ERs) α and β are distributed in most tissues of women and men. ERs are bound by estradiol (E2), a natural hormone, and mediate the... 
PC12 | Phytoestrogens | SERM | Proliferation | Differentiation | Breast cancer cell lines | ENDOCRINE-DISRUPTING CHEMICALS | SURVIVAL | SIGNALING PATHWAYS | ALPHA | NERVE GROWTH-FACTOR | PHARMACOLOGY & PHARMACY | TOXICOLOGY | PC12 CELLS | EXPRESSION | ZEARALENONE | Adrenal Gland Neoplasms - drug therapy | Transcription, Genetic - drug effects | Humans | Isoflavones - pharmacology | Stilbenes - pharmacology | PC12 Cells | Breast Neoplasms - metabolism | Dose-Response Relationship, Drug | Chemokine CXCL12 - genetics | Transfection | MCF-7 Cells | Pheochromocytoma - pathology | Estrogen Receptor alpha - metabolism | Female | Neurogenesis - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Adrenal Gland Neoplasms - pathology | Neurites - drug effects | Phytoestrogens - pharmacology | Pheochromocytoma - metabolism | Response Elements | Rats | Neurites - metabolism | Breast Neoplasms - drug therapy | Estrogen Receptor alpha - drug effects | Nerve Tissue Proteins - metabolism | Neurites - pathology | Pheochromocytoma - drug therapy | Animals | Breast Neoplasms - genetics | Chemokine CXCL12 - metabolism | Estrogen Receptor alpha - genetics | Diet | Breast Neoplasms - pathology | Adrenal Gland Neoplasms - metabolism | Pheochromocytoma - genetics | Cell Proliferation - drug effects | Antineoplastic Agents, Phytogenic - pharmacology | Adrenal Gland Neoplasms - genetics | Selective Estrogen Receptor Modulators - pharmacology | Apigenin - pharmacology | Zearalenone - pharmacology | Analysis | Resveratrol | Phenols | Nerve growth factor | Hormones | Cell differentiation | Estradiol | Isoflavones | Therapeutics | Homeopathy | Materia medica and therapeutics | Index Medicus | Life Sciences | Toxicology | Pharmacology | Pharmaceutical sciences | PUBLIC HEALTH | GROWTH FACTORS | MAMMARY GLANDS | NEOPLASMS | NERVES | ESTRADIOL | PHENOTYPE | CELL PROLIFERATION | ANIMAL TISSUES | RECEPTORS | 60 APPLIED LIFE SCIENCES | BRAIN
Journal Article
Journal of sexual medicine, ISSN 1743-6095, 12/2012, Volume 9, Issue 12, pp. 3028 - 3040
Journal Article
Journal of Vascular Surgery, ISSN 0741-5214, 2010, Volume 51, Issue 4, pp. 972 - 981
Background A greater incidence of varicose veins has been reported in premenopausal women than in men. We hypothesized that the sex differences in venous... 
Surgery | SURGERY | SAPHENOUS VEINS | RISK-FACTORS | CA2+ ENTRY MECHANISMS | ALPHA | PERIPHERAL VASCULAR DISEASE | GENDER-DIFFERENCES | HYPERTENSIVE-RATS | VASCULAR SMOOTH-MUSCLE | CORONARY-ARTERIES | 17-BETA-ESTRADIOL | BETA | Receptors, Angiotensin - metabolism | Estradiol - analogs & derivatives | Receptors, Estrogen - metabolism | Estrogens - pharmacology | Nitriles - pharmacology | Receptors, G-Protein-Coupled - metabolism | Nitric Oxide Synthase - antagonists & inhibitors | Estrogen Antagonists - pharmacology | Male | Fulvestrant | Dose-Response Relationship, Drug | Estrogen Receptor beta - metabolism | Phenylephrine - pharmacology | Varicose Veins - metabolism | Potassium Chloride - pharmacology | Estrogen Receptor alpha - metabolism | Female | Calcium Signaling | Estradiol - pharmacology | Phenols - pharmacology | Pyrazoles - pharmacology | NG-Nitroarginine Methyl Ester - pharmacology | Receptors, Adrenergic, alpha - metabolism | Vasoconstrictor Agents - pharmacology | Estradiol - metabolism | Angiotensin II - pharmacology | Vasodilator Agents - pharmacology | Acetylcholine - pharmacology | Varicose Veins - physiopathology | Enzyme Inhibitors - pharmacology | Rats | Vena Cava, Inferior - metabolism | Rats, Sprague-Dawley | Vasoconstriction - drug effects | Vena Cava, Inferior - drug effects | Receptors, Estrogen - drug effects | Vena Cava, Inferior - physiopathology | Animals | Sex Factors | Nitric Oxide Synthase - metabolism | Vasodilation - drug effects | In Vitro Techniques | Phenols | Estrogen | endothelium | estrogen | nitric oxide | vein | vascular smooth muscle | sex hormones
Journal Article
Neuron (Cambridge, Mass.), ISSN 0896-6273, 2012, Volume 74, Issue 5, pp. 801 - 808
The steroid 17β-estradiol (E2) is well known to influence hippocampal functions such as memory, affective behaviors, and epilepsy. There is growing awareness... 
CA1 | EXCITABILITY | STEROIDS | SYNAPSES | ESTROGEN-RECEPTOR-ALPHA | SYNAPTIC-TRANSMISSION | NEURONS | RELEASE | BINDING | NEUROSCIENCES | Cannabinoid Receptor Modulators - metabolism | CA1 Region, Hippocampal - cytology | Electric Stimulation | Estrogens - pharmacology | Male | Receptors, Metabotropic Glutamate - metabolism | Pyridazines - pharmacology | Lactones - pharmacology | Dose-Response Relationship, Drug | Drug Interactions | Castration | Piperidines - pharmacology | Excitatory Amino Acid Agents - pharmacology | Neurons - physiology | Female | Neurons - drug effects | Endocannabinoids | Estradiol - pharmacology | Pyrazoles - pharmacology | Enzyme Inhibitors - pharmacology | NAD - pharmacology | Cannabinoid Receptor Modulators - agonists | Morpholines - pharmacology | Rats | Biophysics | Rats, Sprague-Dawley | GABA Antagonists - pharmacology | Naphthalenes - pharmacology | Patch-Clamp Techniques | Animals | Benzoxazines - pharmacology | Cannabinoid Receptor Modulators - antagonists & inhibitors | Phenols | In Vitro Techniques | Neural Inhibition - drug effects | Benzodioxoles - pharmacology | Inhibitory Postsynaptic Potentials - drug effects | Brain | Epilepsy | Estrogen | GABA | Hormones, Sex | Estradiol | Studies | Rodents | Gender differences | Behavior | Males | Females | Presynapse | Emotional behavior | gamma -Aminobutyric acid | Neurosteroids | Memory | Sex | Estrogen receptors | Cannabinoid CB1 receptors | Anandamide | Synaptic transmission | Hippocampus | Steroid hormones | Synapses
Journal Article
Inflammation, ISSN 1573-2576, 2014, Volume 38, Issue 2, pp. 637 - 648
Microglial activation has been reported to play an important role in neurodegenerative diseases by producing pro-inflammatory cytokines. Bisphenol A (BPA,... 
Pathology | NF-κB | Medicine & Public Health | ERβ | Rheumatology | Internal Medicine | bisphenol A | immunomodulatory cytokines | Pharmacology/Toxicology | MAPK | ENDOCRINE-DISRUPTING CHEMICALS | INFLAMMATORY RESPONSES | NITRIC-OXIDE SYNTHASE | IMMUNOLOGY | ESTROGEN-RECEPTOR | CNS INFLAMMATION | ER beta | BETA | CELL BIOLOGY | NF-kappa B | ACTIVATED PROTEIN-KINASES | SIGNAL-REGULATED KINASE | EXPRESSION | EXPOSURE | Microglia - metabolism | Estradiol - analogs & derivatives | Estrogens - pharmacology | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Estrogens - analogs & derivatives | JNK Mitogen-Activated Protein Kinases - metabolism | NF-kappa B - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Estrogen Receptor Antagonists - pharmacology | Endocrine Disruptors - pharmacology | Inflammation - drug therapy | Flavonoids - pharmacology | Estradiol - pharmacology | Phenols - pharmacology | Microglia - cytology | Cell Line | NF-kappa B - antagonists & inhibitors | JNK Mitogen-Activated Protein Kinases - antagonists & inhibitors | Neurodegenerative Diseases - pathology | Anti-Inflammatory Agents - pharmacology | Enzyme Activation - drug effects | Anthracenes - pharmacology | Estrogen Receptor Modulators - pharmacology | Animals | MAP Kinase Signaling System - drug effects | Interleukin-6 - biosynthesis | Benzhydryl Compounds - pharmacology | Mice | Tumor Necrosis Factor-alpha - biosynthesis | Index Medicus
Journal Article
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 05/2010, Volume 30, Issue 5, pp. 992 - 999
OBJECTIVE—Selective estrogen receptor modulators (SERMs) inhibit constriction of mammalian conduit arteries. However, it is unknown whether SERMs at... 
Endothelial nitric oxide synthase | Mesenteric artery | Raloxifene | Selective estrogen receptor modulator | Myogenic tone | CA2+ INFLUX | myogenic tone | CARDIOVASCULAR EVENTS | RELAXATION | raloxifene | CORONARY-ARTERY | mesenteric artery | IN-VITRO | ESTROGEN | endothelial nitric oxide synthase | selective estrogen receptor modulator | PERIPHERAL VASCULAR DISEASE | CEREBRAL-ARTERIES | POSTMENOPAUSAL WOMEN | HEMATOLOGY | RECEPTOR MODULATOR RALOXIFENE | Raloxifene Hydrochloride - pharmacology | Estradiol - analogs & derivatives | Phosphorylation | Estrogen Antagonists - pharmacology | Male | Mesenteric Arteries - drug effects | Apamin - pharmacology | Dose-Response Relationship, Drug | Time Factors | Charybdotoxin - pharmacology | Vascular Resistance - drug effects | Female | Blood Pressure - drug effects | Nitric Oxide Synthase Type III - metabolism | Chromones - pharmacology | Estradiol - pharmacology | Potassium Channel Blockers - pharmacology | NG-Nitroarginine Methyl Ester - pharmacology | Vasodilator Agents - pharmacology | Ovariectomy | Enzyme Inhibitors - pharmacology | Morpholines - pharmacology | Rats | Rats, Sprague-Dawley | Nitric Oxide Synthase Type III - antagonists & inhibitors | Animals | Androstadienes - pharmacology | Calcium Signaling - drug effects | Sex Factors | Protein Kinase Inhibitors - pharmacology | Enzyme Activation | Vasodilation - drug effects | In Vitro Techniques | Nitric Oxide - metabolism | Mesenteric Arteries - enzymology | Selective Estrogen Receptor Modulators - pharmacology | Index Medicus
Journal Article