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Chemical Biology & Drug Design, ISSN 1747-0277, 03/2011, Volume 77, Issue 3, pp. 173 - 181
In the present study, Autodock 4.0 was employed to discover potential carbonic anhydrase IX inhibitors that are able to interfere with microtubule dynamics by... 
virtual screening | mechanism‐based drug design | biological screening | Virtual screening | Mechanism-based drug design | Biological screening | CARBONIC-ANHYDRASE-IX | INHIBITS TUBULIN POLYMERIZATION | MULTITARGETED ANTITUMOR AGENTS | MICROTUBULES | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENDOGENOUS MAMMALIAN METABOLITE | BREAST-CANCER CELLS | mechanism-based drug design | FORCE-FIELD | ANTICANCER DRUGS | 2-METHOXYESTRADIOL | CULTURES | Humans | Carbonic Anhydrase II - metabolism | Carbonic Anhydrases - chemistry | Estrone - therapeutic use | Antigens, Neoplasm - chemistry | Carbonic Anhydrase II - antagonists & inhibitors | Carbonic Anhydrase Inhibitors - toxicity | Carbonic Anhydrases - metabolism | Estrone - toxicity | Tubulin - metabolism | Cell Division | Computer Simulation | Drug Design | Antigens, Neoplasm - metabolism | G2 Phase | Female | Tubulin - chemistry | Binding Sites | Colchicine - chemistry | Carbonic Anhydrase IX | Carbonic Anhydrase Inhibitors - therapeutic use | Antimitotic Agents - toxicity | Antimitotic Agents - chemical synthesis | Carbonic Anhydrase Inhibitors - chemical synthesis | Breast Neoplasms - drug therapy | Antimitotic Agents - therapeutic use | Estrone - analogs & derivatives | Cell Line, Tumor | Software | Physiological aspects | Colchicine | Metastasis | Tubulins | Estradiol | Analysis | Index Medicus
Journal Article
Tetrahedron, ISSN 0040-4020, 05/2012, Volume 68, Issue 19, pp. 3685 - 3691
In this paper, we report the first synthesis of aromatic analogs of brassinosteroids. In order to accomplish this task, we explored two different synthetic... 
Brassinosteroids | Bioactivity | Aromatic stigmastanes | A-ring | PERCEPTION | STEROIDS | RECEPTOR KINASE BRI1 | 19-HYDROXY | CHEMISTRY, ORGANIC | ESTRONE | Sterols | Phytosterols | Steroids | Analogs | Synthesis (chemistry) | Tasks | Tetrahedrons | Biochemistry | Hormones | Brasses
Journal Article
Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 2/2005, Volume 55, Issue 2, pp. 159 - 169
Journal Article
Russian Journal of Organic Chemistry, ISSN 1070-4280, 3/2015, Volume 51, Issue 3, pp. 411 - 416
Sulfamates derived from estrogens of the 8α-series have been synthesized, and their effect on the growth of MCF-7 breast cancer cells has been studied. The... 
Chemistry | Organic Chemistry | BREAST-CANCER | 17-BETA-HYDROXYSTEROID-DEHYDROGENASE TYPE-1 | THERAPY | ESTRONE SULFATASE | ANALOGS | ESTRADIOL | CHEMISTRY, ORGANIC | RECEPTOR MODULATORS | POTENT INHIBITORS | DERIVATIVES | SULFATASE INHIBITORS
Journal Article
Stroke, ISSN 0039-2499, 10/2002, Volume 33, Issue 10, pp. 2485 - 2491
Background and Purpose-Although estrogens are neuroprotective, hormonal effects limit their clinical application. Estrogen analogues with neuroprotective... 
Neuroprotection | Receptors, estrogen | Ischemia | Cerebral blood flow | Estrogens | Reperfusion injury | MORTALITY | OXIDATIVE STRESS | MONICA PROJECT | ACTIVATED PROTEIN-KINASE | estrogens | RISK | reperfusion injury | EXPERIMENTAL STROKE | POSTMENOPAUSAL HORMONE-THERAPY | 17-BETA-ESTRADIOL | CLINICAL NEUROLOGY | ischemia | ISCHEMIC DAMAGE | neuroprotection | receptors, estrogen | ESTRADIOL | cerebral blood flow | PERIPHERAL VASCULAR DISEASE | Estradiol - analogs & derivatives | Receptors, Estrogen - metabolism | Humans | Neurons - cytology | Estradiol Congeners - chemistry | Drug Carriers | Dose-Response Relationship, Drug | Brain - blood supply | Estrogen Receptor alpha | Neuroprotective Agents - pharmacology | Female | Infarction, Middle Cerebral Artery - drug therapy | Neurons - drug effects | Estradiol - pharmacology | Adamantane - analogs & derivatives | Disease Models, Animal | Cell Line | Cell Survival - drug effects | Adamantane - pharmacology | Estrone - pharmacology | Neuroprotective Agents - chemistry | Cerebrovascular Circulation - drug effects | Estradiol Congeners - pharmacology | Rats | Infarction, Middle Cerebral Artery - pathology | Rats, Sprague-Dawley | Binding, Competitive - drug effects | Brain - drug effects | Estradiol - chemistry | Animals | Estrone - analogs & derivatives | Receptors, Estrogen - chemistry | Estrone - chemistry | Brain - pathology | Ligands | Mice | Adamantane - chemistry | Glutamic Acid - toxicity | Estrogen Receptor beta | Blood Flow Velocity - drug effects | Index Medicus
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 2011, Volume 52, Issue 35, pp. 4512 - 4514
Journal Article
Steroids, ISSN 0039-128X, 2007, Volume 72, Issue 4, pp. 351 - 359
Journal Article