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Drug Metabolism and Disposition, ISSN 0090-9556, 08/2007, Volume 35, Issue 8, pp. 1308 - 1314
Hepatic uptake carriers of the organic anion-transporting peptide (OATP) family of solute carriers are more and more recognized as being involved in hepatic... 
RAT | SEVERE RHABDOMYOLYSIS | COMBINATION THERAPY | LIVER | PHARMACOLOGY & PHARMACY | CERIVASTATIN | HEPATIC-UPTAKE | TRANSPLANT RECIPIENTS | ROSUVASTATIN | POLYPEPTIDE | FAMILY | Organic Anion Transporters, Sodium-Independent - genetics | Fatty Acids, Monounsaturated - pharmacology | Cricetulus | Hypolipidemic Agents - metabolism | Hypoglycemic Agents - metabolism | Taurocholic Acid - metabolism | Humans | Hepatocytes - metabolism | Simvastatin - pharmacology | Organic Anion Transporters - metabolism | Chromans - metabolism | Hepatocytes - cytology | Indoles - metabolism | Organic Anion Transporters - genetics | Drug Interactions | Anticholesteremic Agents - metabolism | Chromans - pharmacology | Fatty Acids, Monounsaturated - metabolism | Organic Anion Transporters, Sodium-Independent - metabolism | Indoles - pharmacology | Biological Transport - drug effects | Thiazolidinediones - pharmacology | Hepatocytes - drug effects | Solute Carrier Organic Anion Transporter Family Member 1B3 | CHO Cells | Pravastatin - pharmacology | Recombinant Proteins - metabolism | Taurocholic Acid - pharmacology | Cell Line | Cricetinae | Pravastatin - metabolism | Simvastatin - metabolism | Gemfibrozil - pharmacokinetics | Gemfibrozil - pharmacology | Hypolipidemic Agents - pharmacology | Thiazolidinediones - metabolism | Hypoglycemic Agents - pharmacology | Animals | Estrone - analogs & derivatives | Estrone - metabolism | Protein Binding | Fatty Acids, Monounsaturated - pharmacokinetics | Indoles - pharmacokinetics | Kinetics | Solute Carrier Organic Anion Transporter Family Member 1b1 | Anticholesteremic Agents - pharmacology | Gemfibrozil - metabolism
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2008, Volume 584, Issue 1, pp. 57 - 65
The pregnane X receptor is a ligand-activated transcription factor that is abundantly expressed in hepatocytes. Numerous drugs are pregnane X receptor ligands.... 
Organic anion transporting polypeptide | Hepatocyte | Nuclear receptor ligand | Drug–drug interaction | Drug-drug interaction | ORGANIC ANION TRANSPORTER | hepatocyte | ORPHAN NUCLEAR RECEPTORS | organic anion transporting polypeptide | HEPATIC-UPTAKE | RIFAMYCIN SV | SLCO1B3 GENE | IDENTIFICATION | POLYPEPTIDES | nuclear receptor ligand | GENE-EXPRESSION | PHARMACOLOGY & PHARMACY | HUMAN LIVER | drug-drug interaction | Organic Anion Transporters, Sodium-Independent - genetics | Estradiol - analogs & derivatives | Paclitaxel - pharmacology | Receptors, Steroid - metabolism | Cricetulus | Humans | Xenobiotics - pharmacology | Organic Anion Transporters - metabolism | Dose-Response Relationship, Drug | Organic Anion Transporters - genetics | Drug Interactions | Transfection | Chromans - pharmacology | Organic Anion Transporters, Sodium-Independent - metabolism | Organic Anion Transporters, Sodium-Independent - drug effects | Thiazolidinediones - pharmacology | Solute Carrier Organic Anion Transporter Family Member 1B3 | CHO Cells | Estradiol - metabolism | Cricetinae | Clotrimazole - pharmacology | Receptors, Steroid - drug effects | Animals | Estrone - analogs & derivatives | Estrone - metabolism | Ligands | Kinetics | Rifampin - pharmacology | Mifepristone - pharmacology | Solute Carrier Organic Anion Transporter Family Member 1b1 | Organic Anion Transporters - drug effects | Hormones, Sex | Antagonists | Progesterone | Drug interactions | Analysis | Index Medicus | drug-drug interactions | hepatocytes | nuclear receptor ligands
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 08/2007, Volume 35, Issue 8, pp. 1400 - 1407
The elimination process of the endothelin receptor antagonist bosentan (Tracleer) in humans is entirely dependent on metabolism mediated by two cytochrome P450... 
PHARMACOKINETICS | METABOLISM | HEALTHY MALE-SUBJECTS | PHARMACOLOGY & PHARMACY | ANION TRANSPORTING POLYPEPTIDES | HUMAN LIVER | RIFAMYCIN SV | EXPRESSION | DISPOSITION | ENDOTHELIN RECEPTOR ANTAGONIST | DRUG-DRUG INTERACTION | Cytochrome P-450 CYP2C9 | Organic Anion Transporters, Sodium-Independent - genetics | Estradiol - analogs & derivatives | Organic Anion Transporters, Sodium-Independent - antagonists & inhibitors | Cricetulus | Cytochrome P-450 Enzyme Inhibitors | Cyclosporine - pharmacology | Cytochrome P-450 CYP3A | Humans | Warfarin - metabolism | Cytochrome P-450 Enzyme System - metabolism | Dehydroepiandrosterone Sulfate - metabolism | Sulfones - pharmacology | Organic Anion Transporters - metabolism | Pyrimidines - chemistry | Pyrimidines - metabolism | Sildenafil Citrate | Organic Anion Transporters - genetics | Bosentan | Drug Interactions | Organic Anion Transporters, Sodium-Independent - metabolism | Biological Transport - drug effects | Molecular Structure | Solute Carrier Organic Anion Transporter Family Member 1B3 | CHO Cells | Estradiol - metabolism | Aryl Hydrocarbon Hydroxylases - antagonists & inhibitors | Cricetinae | Organic Anion Transporters - antagonists & inhibitors | Sulfonamides - chemistry | Purines - pharmacology | Enzyme Inhibitors - pharmacology | Piperazines - pharmacology | Sulfonamides - pharmacokinetics | Aryl Hydrocarbon Hydroxylases - metabolism | Animals | Estrone - analogs & derivatives | Estrone - metabolism | Sulfonamides - metabolism | Liver-Specific Organic Anion Transporter 1 | Rifampin - pharmacology
Journal Article
European Journal of Pharmaceutical Sciences, ISSN 0928-0987, 05/2012, Volume 46, Issue 1-2, pp. 100 - 105
Journal Article
Pharmaceutical Research, ISSN 0724-8741, 6/2004, Volume 21, Issue 6, pp. 976 - 981
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 09/2001, Volume 61, Issue 18, pp. 6768 - 6776
Journal Article
Journal Article
Journal Article
Journal of Pharmacy and Pharmacology, ISSN 0022-3573, 11/2006, Volume 58, Issue 11, pp. 1499 - 1505
Journal Article
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology, ISSN 0363-6119, 10/2008, Volume 295, Issue 4, pp. 1311 - 1319
Confocal microscopy and image analysis were used to compare driving forces, specificity, and regulation of transport of the fluorescent organic anion, Texas... 
Organic anion transporting polypeptide | Multidrug resistance-associated protein | Confocal imaging | Organic anion transport | Organic anion transporter | organic anion transport | FLOUNDER | PHYSIOLOGY | organic anion transporting polypeptide | INVOLVEMENT | confocal imaging | organic anion transporter | FLUORESCEIN-METHOTREXATE TRANSPORT | SUBSTRATE-SPECIFICITY | OAT3 | multidrug resistance-associated protein | MICE | EXPRESSION | Methotrexate - pharmacology | Propionates - pharmacology | Tetradecanoylphorbol Acetate - pharmacology | Choroid Plexus - metabolism | Male | Quinolines - pharmacology | Xanthenes - metabolism | Protein Kinase C - metabolism | Female | Biological Transport - drug effects | Cyclic AMP-Dependent Protein Kinases - antagonists & inhibitors | Leukotriene C4 - pharmacology | Cyclic AMP-Dependent Protein Kinases - metabolism | Taurocholic Acid - pharmacology | Estrone - pharmacology | Organic Anion Transporters - antagonists & inhibitors | Colforsin - pharmacology | Rats | Protein Kinase C - antagonists & inhibitors | Potassium - pharmacology | Rats, Sprague-Dawley | p-Aminohippuric Acid - pharmacology | Xanthenes - pharmacokinetics | Animals | Estrone - analogs & derivatives | Meglumine - pharmacology | Models, Biological | Organic Anion Transporters - physiology | Squalus acanthias - metabolism | Biological Transport - physiology | Kinetics | In Vitro Techniques | Sodium Cyanide - pharmacology | Index Medicus | Comparative and Evolutionary Physiology
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 2010, Volume 115, Issue 1, pp. 200 - 208
The choroid plexuses (CP) are responsible for transport of micronutrients into brain and clearance of toxic compounds, in addition to its barrier function and... 
confocal laser‐scanning microscopy | fluo‐cAMP | multidrug resistance‐associated protein | organic anion transporting polypeptides | organic anion transporter | transport | choroid plexus | fluo-cAMP | multidrug resistance-associated protein | confocal laser-scanning microscopy | ORGANIC ANION TRANSPORT | MRP4/ABCC4 | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROXIMAL TUBULES | FLUORESCEIN-METHOTREXATE TRANSPORT | CYCLIC-NUCLEOTIDES | MRP4 | NEUROSCIENCES | EFFLUX | EPITHELIAL-CELLS | CGMP | BARRIER PROPERTIES | Potassium - metabolism | Choroid Plexus - metabolism | Male | Sodium - metabolism | Sulfones - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Sildenafil Citrate | Biological Transport, Active | RNA - isolation & purification | Neuroprotective Agents - pharmacology | Organic Anion Transporters, Sodium-Independent - metabolism | Potassium Cyanide - pharmacology | Cyclic AMP - metabolism | Taurocholic Acid - pharmacology | Estrone - pharmacology | Purines - pharmacology | Phosphodiesterase Inhibitors - pharmacology | Rats | Multidrug Resistance-Associated Proteins - antagonists & inhibitors | Reverse Transcriptase Polymerase Chain Reaction | Piperazines - pharmacology | Rats, Sprague-Dawley | Microscopy, Confocal | RNA - biosynthesis | Animals | Estrone - analogs & derivatives | Signal Transduction - drug effects | Signal Transduction - physiology | Multidrug Resistance-Associated Proteins - metabolism | Sulindac - pharmacology | Fluorescent Dyes | Sulfides | Sulfates | Biopolymers | Pharmacy | Neurochemistry | Proteins | Signal transduction | Drug resistance | Rodents | Index Medicus | Choroid plexus | Neuroimaging | Sulfide | Brain | Neuroprotection | MRP protein | organic anion transporting polypeptide | Epithelial cells | Cyclic AMP | Cerebrospinal fluid | Neuromodulation | Micronutrients | sulindac | Anions | Fluoride | Toxicants |