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Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 2008, Volume 16, Issue 22, pp. 9847 - 9857
Piperine analogs derived from piperine have been shown to possess potent efflux pump inhibitory activity against NorA system of having better potentiation... 
Piperine analogs | Ciprofloxacin | NorA efflux pumps inhibitor | Potentiator | BACTERIA | CHEMISTRY, MEDICINAL | TRANSPORTERS | MEDIATED DRUG-RESISTANCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANTIBACTERIAL | CHEMISTRY, ORGANIC | FLUOROQUINOLONE RESISTANCE | P-GLYCOPROTEIN | MULTIDRUG-RESISTANCE | DERIVATIVES | MOLECULAR-MECHANISMS | CONSTITUENTS | Polyunsaturated Alkamides - chemistry | Nucleic Acid Synthesis Inhibitors - pharmacology | Alkaloids - chemical synthesis | Ethidium - metabolism | Microbial Sensitivity Tests | Piperidines - pharmacology | Anti-Bacterial Agents - chemistry | Benzodioxoles - chemistry | Benzodioxoles - chemical synthesis | Polyunsaturated Alkamides - chemical synthesis | Staphylococcus aureus - metabolism | Bacterial Proteins - antagonists & inhibitors | Piperidines - chemistry | Alkaloids - pharmacology | Enzyme Inhibitors - pharmacology | Ciprofloxacin - pharmacology | Multidrug Resistance-Associated Proteins - antagonists & inhibitors | Piperidines - chemical synthesis | Nucleic Acid Synthesis Inhibitors - chemistry | Polyunsaturated Alkamides - pharmacology | Ciprofloxacin - chemistry | Bacterial Proteins - metabolism | Anti-Bacterial Agents - pharmacology | Staphylococcus aureus - drug effects | Multidrug Resistance-Associated Proteins - metabolism | Alkaloids - chemistry | Benzodioxoles - pharmacology | Staphylococcus aureus | Index Medicus
Journal Article
Journal of Antimicrobial Chemotherapy, ISSN 0305-7453, 6/2008, Volume 61, Issue 6, pp. 1270 - 1276
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 1150 - 7
Journal Article
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0223-5234, 08/2013, Volume 66, pp. 499 - 507
Efflux pump (EP) induces resistance in mycobacteria and hence could be explored as a new target for the discovery of anti-TB agents. In search for efflux pump... 
Caesalpinia digyna | Homoisoflavonoid | PLANT | CHEMISTRY, MEDICINAL | HOMOISOFLAVONOIDS | INTRINSIC DRUG-RESISTANCE | CAESALPINIA-DIGYNA | Efflux pump | Bonducellin | ETHIDIUM-BROMIDE EFFLUX
Journal Article
RSC Advances, ISSN 2046-2069, 2015, Volume 5, Issue 110, pp. 90632 - 90644
A new series of 13-pyridinealkyl berberine analogues was synthesized and their DNA binding efficacy studied by employing spectroscopic, calorimetric and... 
PALMATINE | ACTIVATION | DAUNOMYCIN | ETHIDIUM | ISOQUINOLINE ALKALOIDS | GROWTH | ALKALOIDS BERBERINE | TRANSFER-RNA | BINDING | CHEMISTRY, MULTIDISCIPLINARY | BASE | Binding | Analogue | Binding energy | Deoxyribonucleic acid | Breast | Calorimetry | Entropy | Apoptosis
Journal Article
DNA and Cell Biology, ISSN 1044-5498, 02/2011, Volume 30, Issue 2, pp. 123 - 133
To understand the structure–activity relationship of isoquinoline alkaloids, absorption, fluorescence, circular dichroism, and thermodynamics were employed to... 
Original Research Articles | Berberine - chemistry | Nucleic Acid Denaturation | Spectrometry, Fluorescence | Ethers - chemistry | Ethidium - metabolism | Structure-Activity Relationship | DNA - metabolism | Berberine - metabolism | DNA - chemistry | Absorption | Animals | Cattle | Calorimetry | Plants - chemistry | Circular Dichroism | Transition Temperature | Index Medicus
Journal Article
MedChemComm, ISSN 2040-2503, 2014, Volume 5, Issue 2, pp. 226 - 231
A series of 13-diphenylalkyl berberine derivatives were designed and synthesized, and their base specificity and energetics of DNA binding were evaluated using... 
THERMODYNAMIC PROFILE | PALMATINE | CHEMISTRY, MEDICINAL | ETHIDIUM | DEOXYRIBONUCLEIC ACIDS | SMALL MOLECULES | BIOCHEMISTRY & MOLECULAR BIOLOGY | ISOQUINOLINE ALKALOIDS | SEQUENCE | SANGUINARINE | INDUCTION | INTERCALATION
Journal Article
Letters in Drug Design and Discovery, ISSN 1570-1808, 01/2012, Volume 9, Issue 1, pp. 12 - 16
Three groups of distamycin analogues containing benzene units, potential minor groove binders, each containing six compounds, have been synthesized using... 
Combinatorial chemistry | Distamycin analogues | Parallel synthesis | Solid phase synthesis | DNA binding | NETROPSIN | CHEMISTRY, MEDICINAL | PYRROLE | SOLID-PHASE SYNTHESIS | ANTITUMOR | MINOR-GROOVE BINDERS | AMINO-ACIDS | AGENTS | IMIDAZOLE | POLYAMIDES | Ethidium bromide | Plasmids | Benzene | DNA | Fluorescence | Drug discovery | distamycin | Drug development
Journal Article