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Science, ISSN 0036-8075, 03/2017, Volume 355, Issue 6330, pp. 1206 - 1211
Journal Article
Journal Article
Tuberculosis, ISSN 1472-9792, 2015, Volume 97, pp. 126 - 136
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 01/2007, Volume 204, Issue 1, pp. 73 - 78
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 04/2011, Volume 54, Issue 8, pp. 2994 - 3010
Journal Article
BBA - Proteins and Proteomics, ISSN 1570-9639, 03/2019, Volume 1867, Issue 3, pp. 248 - 258
The EthR is a member of the TetR family of repressors, controlling the expression of EthA, a mono-oxygenase responsible for the bioactivation of the prodrug... 
X-ray crystallography | Ethionamide | Binding interaction | Drug design | Tuberculosis | Small molecule | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | TETR FAMILY | DRUG ETHIONAMIDE | VALIDATION | TRANSCRIPTIONAL REPRESSOR ETHR | ETHIONAMIDE BOOSTERS | IDENTIFICATION | DISCOVERY | REPLACEMENT | BIOPHYSICS | INHIBITORS
Journal Article
Journal Article
Chemical Communications, ISSN 1359-7345, 2017, Volume 53, Issue 25, pp. 3527 - 3530
EthR is a transcriptional repressor that increases Mycobacterium tuberculosis resistance to ethionamide. In this study, the EthR-DNA interaction has been... 
ETHIONAMIDE RESISTANCE | ASSEMBLIES | TUBERCULOSIS | COMPLEXES | BINDING-PROTEIN | INHIBITORS | REPRESSOR | CHEMISTRY, MULTIDISCIPLINARY | FAMILY
Journal Article
BBA - Proteins and Proteomics, ISSN 1570-9639, 09/2016, Volume 1864, Issue 9, pp. 1177 - 1187
Ar-BVMO is a recently discovered Baeyer-Villiger monooxygenase from the genome of S13 closely related to medically relevant ethionamide monooxygenase EtaA... 
Drug metabolites | BVMO | Ethionamide | Flavoprotein | Isothermal calorimetry | Stopped-flow | MYCOBACTERIUM-TUBERCULOSIS | BIOCATALYSTS | HALF-REACTION | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PRODRUG ACTIVATOR ETAA | CYCLOHEXANONE MONOOXYGENASE | CONTAINING MONO-OXYGENASE | ACINETOBACTER-RADIORESISTENS | BIOPHYSICS | HYDROGEN-PEROXIDE | FLAVIN-CONTAINING MONOOXYGENASE | Glycine - metabolism | Bacterial Proteins - chemistry | Substrate Specificity | Alanine - chemistry | Mixed Function Oxygenases - metabolism | Mixed Function Oxygenases - chemistry | Ethionamide - metabolism | Acinetobacter - enzymology | Glycine - chemistry | Cloning, Molecular | Escherichia coli - metabolism | Recombinant Proteins - metabolism | Amino Acid Sequence | Catalytic Domain | Gene Expression | Biocatalysis | Mutagenesis, Site-Directed | Oxidation-Reduction | Soil Microbiology | Bacterial Proteins - genetics | Recombinant Proteins - chemistry | Acinetobacter - genetics | Alanine - metabolism | Recombinant Proteins - genetics | Arginine - chemistry | Sequence Homology, Amino Acid | Ethionamide - chemistry | Sequence Alignment | Escherichia coli - genetics | Ketones - chemistry | Bacterial Proteins - metabolism | Flavins - chemistry | Kinetics | Mutation | Mixed Function Oxygenases - genetics | Ketones - metabolism | Arginine - metabolism | Flavins - metabolism | Enzymes | Genetic aspects | Liquid chromatography | Metabolites | Index Medicus
Journal Article
Antimicrobial Agents & Chemotherapy, ISSN 0066-4804, 03/2001, Volume 45, Issue 3, pp. 810 - 814
Ethionamide (ETA) is a bacteriostatic, isonicotinic acid-derived antituberculosis agent. It is used in combination for the treatment of clinical tuberculosis... 
ethionamide
Journal Article
Scientific reports, ISSN 2045-2322, 05/2018, Volume 8, Issue 1, pp. 7596 - 1
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. 
Nanoparticles | Ethionamide | Tuberculosis
Journal Article
Journal of Molecular Graphics and Modelling, ISSN 1093-3263, 10/2017, Volume 77, pp. 386 - 398
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 12/2015, Volume 106, pp. 157 - 166
Tyrosinase catalyzes two distinct sequential reactions in melanin biosynthesis: the hydroxylation of tyrosine to DOPA followed by the oxidation of DOPA to... 
Docking simulation | Carbothioamide compounds | Tyrosinase inhibitors | Ethionamide | Antituberculosis drugs | Chemoinformatics | Prothionamide | MELANOMA B16 CELLS | CHEMISTRY, MEDICINAL | CRYSTAL-STRUCTURE | 3,4-DIHYDROQUINAZOLINE-2(1H)-THIONES