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Birth Defects Research Part B - Developmental and Reproductive Toxicology, ISSN 1542-9733, 02/2013, Volume 98, Issue 1, pp. 41 - 53
Journal Article
Journal Article
Nature Medicine, ISSN 1078-8956, 2012, Volume 18, Issue 4, pp. 572 - 579
Nat Med. 2012 Mar 4;18(4):572-9. doi: 10.1038/nm.2667. Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver... 
MEDICINE, RESEARCH & EXPERIMENTAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | HUMAN JAGGED1 | CELL BIOLOGY | ALAGILLE-SYNDROME | BILE-DUCT DEVELOPMENT | REGULATES FORMATION | MOUSE MODEL | CHOLINE-DEFICIENT | GENE-EXPRESSION | NUMB | OVAL CELLS | DIFFERENTIATION | Wnt3A Protein - metabolism | Ethionine - administration & dosage | Keratins, Hair-Specific - genetics | Receptors, Notch - metabolism | Humans | Middle Aged | Liver Diseases - pathology | Cell Communication - physiology | Male | RNA, Messenger - metabolism | Young Adult | Cell Differentiation - genetics | Intercellular Signaling Peptides and Proteins - metabolism | Liver Regeneration - genetics | Biliary Tract - metabolism | Serrate-Jagged Proteins | Adult | Antigens, Differentiation - metabolism | Female | Membrane Proteins - metabolism | Cell Differentiation - physiology | Hepatocytes - physiology | Jagged-1 Protein | Calcium-Binding Proteins - metabolism | Mice, Inbred C57BL | Cells, Cultured | Gene Expression Regulation - physiology | Mice, Transgenic | gamma-Glutamyltransferase - metabolism | Biliary Tract - physiopathology | Cell Communication - genetics | Liver Regeneration - physiology | beta Catenin - genetics | Biliary Tract - pathology | Nerve Tissue Proteins - metabolism | Macrophages - metabolism | Animals | Creatine Kinase - metabolism | Signal Transduction - physiology | Stem Cell Niche - physiology | Stem Cells - physiology | Aged | Mice | Chronic Disease | Liver diseases | Physiological aspects | Development and progression | Genetic aspects | Research | Macrophages | Cell differentiation | Wnt proteins | Signal transduction | Cellular biology | Gene expression | Index Medicus
Journal Article
Journal Article
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 08/2007, Volume 151, Issue 7, pp. 998 - 1005
Background and purpose: The mortality associated with acute pancreatitis (AP) is largely attributable to abnormalities that occur in distant organs and... 
therapeutic administration | poly(ADP‐ribose) polymerase | liver injury | lung injury | inflammation | acute pancreatitis | Poly(ADP-ribose) polymerase | Inflammation | Acute pancreatitis | Therapeutic administration | Liver injury | Lung injury | NADPH OXIDASE | ACTIVATION | poly(ADP-ribose) polymerase | HEMORRHAGIC-PANCREATITIS | SUPPLEMENTED DIET | NECROTIZING PANCREATITIS | NECROSIS | ADP-RIBOSE POLYMERASE | CHOLINE-DEFICIENT | PHARMACOLOGY & PHARMACY | INFLAMMATORY MEDIATORS | Amylases - blood | Ethionine - administration & dosage | Lipase - blood | Liver Diseases - pathology | Alanine Transaminase - blood | Pancreatitis - drug therapy | Lung Diseases - drug therapy | Interleukin-1beta - blood | Time Factors | Interleukin-6 - blood | Liver Diseases - enzymology | Female | Lung Diseases - enzymology | Severity of Illness Index | Acute Disease | Phenanthrenes - therapeutic use | Enzyme Inhibitors - pharmacology | Treatment Outcome | Methionine - administration & dosage | Mice, Inbred Strains | Enzyme Inhibitors - therapeutic use | Poly(ADP-ribose) Polymerase Inhibitors | Pancreatitis - enzymology | Phenanthrenes - pharmacology | Animals | Aspartate Aminotransferases - blood | Choline - administration & dosage | Pancreatitis - pathology | Liver Diseases - drug therapy | Mice | Lung Diseases - pathology | Peroxidase - blood | Dietary Supplements | Index Medicus | Research Papers
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 12/2000, Volume 192, Issue 12, pp. 1809 - 1818
Hepatic stem cells (oval cells) proliferate within the liver after exposure to a variety of hepatic carcinogens and can generate both hepatocytes and bile duct... 
Hepatocellular | Interleukin 6 | Carcinoma | Cytokines | Liver regeneration | Stem cells | RAT-LIVER | PROGENITOR CELLS | MEDICINE, RESEARCH & EXPERIMENTAL | stem cells | carcinoma, hepatocellular | C-KIT | IMMUNOLOGY | HEPATIC STEM-CELLS | interleukin 6 | D-GALACTOSAMINE | cytokines | LACKING TYPE-1 | OVAL CELL-PROLIFERATION | GROWTH-FACTOR | liver regeneration | BILIARY EPITHELIAL-CELLS | TRANSGENIC MICE | Liver - pathology | Ethionine - administration & dosage | Cell Count | Tumor Necrosis Factor-alpha - genetics | Liver Neoplasms - chemically induced | Precancerous Conditions - metabolism | RNA, Messenger - metabolism | Stem Cells - metabolism | Carcinogens - administration & dosage | Receptors, Tumor Necrosis Factor - physiology | Carcinogens - pharmacology | Cell Division | Gene Deletion | Liver Neoplasms - pathology | Precancerous Conditions - pathology | Receptors, Tumor Necrosis Factor - genetics | Interleukin-6 - genetics | Liver Neoplasms - genetics | Signal Transduction | Liver - metabolism | RNA, Messenger - genetics | Cells, Cultured | Gene Expression Regulation | Ethionine - pharmacology | Precancerous Conditions - genetics | Mice, Knockout | Animals | Diet | Histocytochemistry | Liver Neoplasms - metabolism | Liver - cytology | Mice | Precancerous Conditions - chemically induced | tumor necrosis factor receptors | Index Medicus | Original
Journal Article
Gastroenterology, ISSN 0016-5085, 2008, Volume 135, Issue 3, pp. 969 - 979.e1
Journal Article
International Journal of Biochemistry and Cell Biology, ISSN 1357-2725, 2007, Volume 39, Issue 12, pp. 2226 - 2239
Oval cells have great potential for use in cell therapy to treat liver disease, however this cannot be achieved until the factors which govern their... 
Primary culture | Liver progenitor (oval) cell lines | Cell therapy | Liver regeneration | Inducible differentiation | RAT-LIVER | primary culture | liver progenitor (oval) cell lines | TYROSINE AMINOTRANSFERASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | inducible differentiation | LIVER PROGENITOR CELLS | PROLIFERATION | KNOCKOUT MICE | CELL BIOLOGY | HEPATOCYTE DIFFERENTIATION | IN-VITRO | cell therapy | GENE-EXPRESSION | STEM-CELL | liver regeneration | Immunohistochemistry | Ethionine - administration & dosage | Gene Expression - drug effects | Male | Stem Cells - cytology | Hepatocytes - metabolism | Stem Cells - metabolism | Cell Culture Techniques - methods | Hepatocytes - cytology | Liver - drug effects | Keratin-19 - analysis | Thy-1 Antigens - genetics | Antigens, Differentiation - metabolism | Tyrosine Transaminase - metabolism | GATA2 Transcription Factor - genetics | Hepatocytes - drug effects | Antigens, Differentiation - analysis | Liver - metabolism | Mice, Inbred C57BL | Connexins - genetics | Cadherins - analysis | Mice, Transgenic | Cell Separation - methods | Reverse Transcriptase Polymerase Chain Reaction | Food, Formulated | Keratin-19 - genetics | Tyrosine Transaminase - genetics | Animals | Choline - administration & dosage | Cell Differentiation - drug effects | Stem Cells - drug effects | Liver - cytology | Mice | Cell Line, Transformed | Index Medicus
Journal Article
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 04/2013, Volume 268, Issue 1, pp. 79 - 89
Journal Article
Hepatology, ISSN 0270-9139, 09/2001, Volume 34, Issue 3, pp. 519 - 522
Several reliable and reproducible methods are available to induce oval cells in rat liver. Effective methods often involve inhibiting proliferation in... 
RAT-LIVER | HEPATOCYTES | ORIGIN | CARCINOGENESIS | POPULATIONS | GASTROENTEROLOGY & HEPATOLOGY | LINEAGES | Immunohistochemistry | Animals | Ethionine - administration & dosage | Diet | Cell Size | Liver - cytology | Mice | Choline Deficiency - pathology | Ethionine - pharmacology | Mice, Inbred Strains | Index Medicus
Journal Article