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Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 11/2014, Volume 58, Issue 11, pp. 6413 - 6423
Journal Article
Journal of Neurophysiology, ISSN 0022-3077, 12/2005, Volume 94, Issue 6, pp. 4131 - 4144
The effects of pregnenolone sulfate (PREGS), a putative neurosteroid, on the transmission of perforant path–granule cell synapses were investigated with an... 
TRANSMITTER RELEASE | PHYSIOLOGY | GLUTAMATE RELEASE | CALCIUM-CHANNELS | LINKED-IMMUNOSORBENT-ASSAY | NICOTINIC ACETYLCHOLINE-RECEPTOR | INCREASES HIPPOCAMPAL ACETYLCHOLINE | RAT-BRAIN | ALPHA-BUNGAROTOXIN | AGED RATS | NEUROSCIENCES | METHYL-D-ASPARTATE | Excitatory Postsynaptic Potentials - radiation effects | Synaptic Transmission - physiology | Rats, Wistar | Calcium - metabolism | 2-Amino-5-phosphonovalerate - pharmacology | Kainic Acid - analogs & derivatives | Male | Nicotinic Antagonists - pharmacology | Excitatory Postsynaptic Potentials - drug effects | Diagnostic Imaging - methods | Dose-Response Relationship, Drug | Drug Interactions | Time Factors | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Pregnenolone - pharmacology | Tetrodotoxin - pharmacology | Neurons - drug effects | Electric Stimulation - methods | Haloperidol - pharmacology | Nicotinic Agonists - pharmacology | Calcium - pharmacology | Presynaptic Terminals - drug effects | Kainic Acid - pharmacology | Rats | Excitatory Amino Acid Antagonists - pharmacology | Aconitine - analogs & derivatives | Bicuculline - pharmacology | Aconitine - pharmacology | Calcium Channel Blockers - pharmacology | Hippocampus - cytology | Ethylenediamines - pharmacology | GABA Antagonists - pharmacology | Animals | Benzylidene Compounds - pharmacology | Analysis of Variance | Dopamine Antagonists - pharmacology | Pyridines - pharmacology | In Vitro Techniques | Bungarotoxins - pharmacology
Journal Article
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 12/2017, Volume 142, pp. 8 - 31
Metallodrugs offer potential for unique mechanism of drug action based on the choice of the metal, its oxidation state, the types and number of coordinated... 
Proteins | Cytotoxicity | Anticancer agents | DNA | CHEMISTRY, MEDICINAL | SACCHARINATE COMPLEX | STRUCTURAL-CHARACTERIZATION | DNA-BINDING PROPERTIES | PT(II) COMPLEXES | SUBSTITUTION-REACTIONS | ANTITUMOR-ACTIVITY | IN-VITRO CYTOTOXICITY | POLYPYRIDYL COMPLEXES | THIOREDOXIN REDUCTASE | CELLULAR PHARMACOLOGY | Humans | Antineoplastic Agents - therapeutic use | Platinum - toxicity | Platinum - chemistry | Ruthenium - chemistry | Antineoplastic Agents - toxicity | Ruthenium - therapeutic use | Coordination Complexes - pharmacology | Antineoplastic Agents - pharmacology | Platinum - pharmacology | Coordination Complexes - toxicity | Gold - toxicity | Gold - chemistry | Ruthenium - toxicity | Platinum - therapeutic use | Palladium - pharmacology | Gold - pharmacology | Antineoplastic Agents - chemistry | Coordination Complexes - chemistry | Drug Discovery | Palladium - toxicity | Ruthenium - pharmacology | Neoplasms - drug therapy | Coordination Complexes - therapeutic use | Animals | Palladium - therapeutic use | Gold - therapeutic use | Palladium - chemistry | Enzymes | Chromosomal proteins | Ruthenium | Thiols | Lung cancer | Leukemia | Albumin | Palladium | Antineoplastic agents | Ethylenediamines | Antimitotic agents | Cytokinins | Chemotherapy | Colon cancer | Gliomas | Prostate cancer | Cervical cancer | Cancer | Protein binding | Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2014, Volume 9, Issue 2, p. e89985
Dextromethorphan is an antitussive with a high margin of safety that has been hypothesized to display rapid-acting antidepressant activity based on... 
DEPRESSION | LIGANDS | NOREPINEPHRINE | BEHAVIORAL DESPAIR | MULTIDISCIPLINARY SCIENCES | DRUG DISCOVERY | MICE | SEROTONIN | RAT-BRAIN | FORCED SWIMMING TEST | BINDING | Receptors, N-Methyl-D-Aspartate - antagonists & inhibitors | Dextromethorphan - pharmacology | Cytochrome P-450 Enzyme Inhibitors | Receptors, N-Methyl-D-Aspartate - metabolism | Cytochrome P-450 Enzyme System - metabolism | Behavior, Animal - physiology | Male | Adrenergic alpha-Antagonists - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Quinidine - pharmacology | Receptors, sigma - antagonists & inhibitors | Piperazines - pharmacology | Ethylenediamines - pharmacology | Dose-Response Relationship, Drug | Swimming - physiology | Animals | Protein Binding | Behavior, Animal - drug effects | Antidepressive Agents - pharmacology | Mice | Kinetics | Ketamine - pharmacology | Receptors, sigma - metabolism | Methyl aspartate | Dextromethorphan | Antidepressants | Analysis | Cytochrome | Glutamic acid receptors (ionotropic) | Glutamic acid receptors | Kinases | Proteins | Receptors | Metabolites | Rodents | Pretreatment | Pharmaceutical sciences | Binding | Dopamine | Serotonin | Saturation | Cytochrome P450 | Health psychology | N-Methyl-D-aspartic acid receptors | Pharmacology | Bioavailability | Metabolism | Pentazocine | Medicine | Studies | Hypotheses | Ketamine | Quinidine | Ligands | Psychiatry
Journal Article
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 07/2010, Volume 54, Issue 7, pp. 2840 - 2846
Journal Article