X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (2997) 2997
Publication (685) 685
Book Chapter (19) 19
Book Review (10) 10
Conference Proceeding (9) 9
Book / eBook (3) 3
Dissertation (3) 3
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
eukaryotic initiation factor-2 - metabolism (2064) 2064
animals (1866) 1866
humans (1471) 1471
phosphorylation (1399) 1399
index medicus (1281) 1281
biochemistry & molecular biology (889) 889
mice (822) 822
protein biosynthesis (744) 744
eukaryotic initiation factor-2 - genetics (650) 650
cell biology (610) 610
eif-2 kinase - metabolism (514) 514
eukaryotic initiation factor-2 (454) 454
apoptosis (452) 452
cell line (448) 448
proteins (420) 420
rna, messenger - metabolism (384) 384
rats (371) 371
unfolded protein response (368) 368
peptide initiation factors - metabolism (359) 359
proteins - metabolism (348) 348
signal transduction (348) 348
molecular sequence data (340) 340
male (339) 339
er stress (303) 303
endoplasmic-reticulum stress (296) 296
messenger-rna (285) 285
article (283) 283
cells, cultured (280) 280
cell line, tumor (275) 275
amino acid sequence (271) 271
gene expression (269) 269
rna, messenger - genetics (266) 266
gene expression regulation (257) 257
translation (256) 256
expression (253) 253
research article (251) 251
research (250) 250
protein binding (246) 246
female (245) 245
kinetics (243) 243
activation (240) 240
gene-expression (238) 238
phosphorylation - drug effects (237) 237
cells (236) 236
endoplasmic reticulum - metabolism (236) 236
mutation (235) 235
protein synthesis (235) 235
hela cells (233) 233
rna (229) 229
argonaute proteins (227) 227
translation initiation (227) 227
base sequence (225) 225
rabbits (224) 224
translational control (213) 213
oxidative stress (211) 211
ribosomes - metabolism (211) 211
protein kinases - metabolism (208) 208
protein-serine-threonine kinases - metabolism (203) 203
protein biosynthesis - drug effects (191) 191
apoptosis - drug effects (190) 190
eif-2 kinase - genetics (188) 188
endoplasmic reticulum stress (186) 186
eukaryotic initiation factor-2 - chemistry (182) 182
kinases (178) 178
multidisciplinary sciences (178) 178
protein-synthesis (175) 175
stress (172) 172
binding sites (171) 171
mammalian-cells (169) 169
physiological aspects (167) 167
endoplasmic reticulum (166) 166
guanosine triphosphate - metabolism (163) 163
inhibition (163) 163
blotting, western (161) 161
virology (161) 161
transcription factor chop - metabolism (159) 159
viruses (159) 159
peptide chain initiation, translational (157) 157
double-stranded-rna (154) 154
signal transduction - drug effects (154) 154
activating transcription factor 4 - metabolism (153) 153
transfection (153) 153
macromolecular substances (152) 152
endoplasmic reticulum stress - drug effects (149) 149
reticulocytes - metabolism (149) 149
rna interference (149) 149
cancer (148) 148
mice, inbred c57bl (146) 146
models, biological (145) 145
oncology (143) 143
enzyme activation (142) 142
biology (139) 139
biophysics (139) 139
saccharomyces-cerevisiae (135) 135
biochemistry (134) 134
guanine nucleotide exchange factors (133) 133
eif-2 kinase (132) 132
protein folding (130) 130
heat-shock proteins - metabolism (129) 129
saccharomyces cerevisiae - genetics (129) 129
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (2975) 2975
Chinese (11) 11
Japanese (10) 10
Polish (3) 3
Russian (3) 3
French (2) 2
German (1) 1
Hungarian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal of Biological Chemistry, ISSN 0021-9258, 04/2005, Volume 280, Issue 14, pp. 14189 - 14202
Protein ubiquitination and subsequent degradation by the proteasome are important mechanisms regulating cell cycle, growth and differentiation, and apoptosis.... 
INDUCED GENE-EXPRESSION | MESSENGER-RNA TRANSLATION | TARGETED DISRUPTION | OXIDATIVE STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENDOPLASMIC-RETICULUM STRESS | WOLCOTT-RALLISON-SYNDROME | CELL-SURVIVAL | NF-KAPPA-B | MAMMALIAN-CELLS | EIF2 KINASE GCN2 | Protein Kinases - metabolism | Phosphorylation | Protein Biosynthesis | Protein Kinases - genetics | Ubiquitin - metabolism | Activating Transcription Factor 4 | Protein Subunits - metabolism | Antineoplastic Agents - metabolism | DNA-Binding Proteins - metabolism | RNA Splicing | Transcription Factor CHOP | Trans-Activators - genetics | Eukaryotic Initiation Factor-2 - metabolism | Membrane Proteins - metabolism | CCAAT-Enhancer-Binding Proteins - genetics | Nuclear Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Fibroblasts - metabolism | Protein Subunits - genetics | CCAAT-Enhancer-Binding Proteins - metabolism | Membrane Proteins - genetics | Cells, Cultured | Gene Expression Regulation | Protein-Serine-Threonine Kinases - genetics | Nuclear Proteins - metabolism | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Regulatory Factor X Transcription Factors | Mice, Knockout | Transcription Factors - metabolism | Animals | Eukaryotic Initiation Factor-2 - genetics | Trans-Activators - metabolism | Fibroblasts - cytology | Mice | Apoptosis - physiology | Proteasome Endopeptidase Complex - metabolism | Proteasome Inhibitors
Journal Article
Molecular & Biochemical Parasitology, ISSN 0166-6851, 12/2019, Volume 234, p. 111223
is an intestinal parasite infecting over 50 million people worldwide and is the causative agent of amebic dysentery and amoebic liver abscess. In the human... 
ER stress | Entamoeba histolytica | Nitrosative stress | Translational control | Eukaryotic initiation factor-2 alpha
Journal Article
NEUROREPORT, ISSN 0959-4965, 12/2002, Volume 13, Issue 18, pp. 2429 - 2432
Inhibition of protein translation is a mode of inducing neuronal apoptosis and neurodegeneration in Alzheimer's disease (AD). Phosphorylation of eukaryotic... 
ACTIVATION | FACTOR 2-ALPHA KINASE | CASPASE-3 | neurodegeneration | TAU | REPERFUSION | PROTEIN-SYNTHESIS | NEUROSCIENCES | granulovacuolar degeneration | INHIBITION | PKR | double-stranded RNA-dependent protein kinase | eukaryotic initiation factor-2 alpha | Alzheimer's disease | BRAIN
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2010, Volume 107, Issue 40, pp. 17200 - 17205
Journal Article
Vaccine, ISSN 0264-410X, 2013, Volume 31, Issue 52, pp. 6225 - 6231
Highlights • Vaccination with Toxoplasma gondii IF2α DNA vaccine induced specific humoral and cellular responses. • Significant production of IFN-γ and IL-2... 
Allergy and Immunology | DNA vaccine | Eukaryotic initiation factor-2α (TgIF2α) | Mice | Toxoplasma gondii | Protective immunity | Toxoplasmosis | MEDICINE, RESEARCH & EXPERIMENTAL | Eukaryotic initiation factor-2 alpha (TgIF2 alpha) | IFN-GAMMA | VACCINE | PLASMID | IMMUNOLOGY | PERFORIN-LIKE PROTEIN-1 | CD8(+) T-CELLS | RESPONSES | CD4(+) | INFECTION | PARASITE | Toxoplasma - immunology | Vaccines, DNA - genetics | Virulence Factors - genetics | Immunoglobulin G - blood | Vaccines, DNA - immunology | Virulence Factors - immunology | Protozoan Proteins - genetics | Th1 Cells - immunology | Toxoplasmosis, Animal - prevention & control | Vaccines, DNA - administration & dosage | CD4-Positive T-Lymphocytes - immunology | Antibodies, Protozoan - blood | Toxoplasmosis, Animal - parasitology | Female | Brain - parasitology | Disease Models, Animal | Protozoan Vaccines - genetics | Protozoan Vaccines - immunology | Interferon-gamma - secretion | Injections, Intramuscular | Protozoan Vaccines - administration & dosage | Animals | Toxoplasma - genetics | Eukaryotic Initiation Factor-2 - genetics | Survival Analysis | Toxoplasmosis, Animal - immunology | Brain - pathology | CD8-Positive T-Lymphocytes - immunology | Eukaryotic Initiation Factor-2 - immunology | Interleukin-2 - secretion | Protozoan Proteins - immunology | Toxoplasmosis, Animal - pathology
Journal Article
2012, Progress in Molecular Biology and Translational Science, ISBN 0123964563, Volume 106, 32
The unfolded protein response, also known as endoplasmic reticulum (ER) stress, has been implicated in numerous human diseases, including atherosclerosis,... 
DIABETES-MELLITUS | INDUCED GENE-EXPRESSION | MESSENGER-RNA TRANSLATION | UNFOLDED PROTEIN RESPONSE | FACTOR 2-ALPHA EIF2-ALPHA | ER STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BETA-CELL FAILURE | ENDOPLASMIC-RETICULUM STRESS | QUALITY-CONTROL | INDUCIBLE PROTEIN | Neoplasms - metabolism | Guanabenz - therapeutic use | Thiourea - therapeutic use | Humans | Phosphoprotein Phosphatases - metabolism | Eukaryotic Cells - metabolism | Thiourea - pharmacology | Endoplasmic Reticulum Stress - genetics | Molecular Targeted Therapy | Neurodegenerative Diseases - drug therapy | Protein Processing, Post-Translational - drug effects | Protein Folding - drug effects | Eukaryotic Initiation Factor-2 - metabolism | Phosphorylation - drug effects | Unfolded Protein Response - drug effects | Atherosclerosis - drug therapy | Endoplasmic Reticulum Stress - drug effects | Unfolded Protein Response - genetics | Diabetes Mellitus - drug therapy | Diabetes Mellitus - metabolism | Mice, Transgenic | Phosphoprotein Phosphatases - antagonists & inhibitors | Neurodegenerative Diseases - metabolism | Cinnamates - pharmacology | Atherosclerosis - metabolism | Gene Knock-In Techniques | Mice, Knockout | Neoplasms - drug therapy | Guanabenz - pharmacology | Animals | Models, Biological | Protein Biosynthesis - drug effects | Mice | Proteasome Endopeptidase Complex - metabolism | Cinnamates - therapeutic use | Thiourea - analogs & derivatives | Endoplasmic Reticulum Stress - physiology
Book Chapter
Journal Article
NeuroReport, ISSN 0959-4965, 12/2002, Volume 13, Issue 18, pp. 2429 - 2432
Inhibition of protein translation is a mode of inducing neuronal apoptosis and neurodegeneration in Alzheimerʼs disease (AD). Phosphorylation of eukaryotic... 
Granulovacuolar degeneration | Double-stranded RNA-dependent protein kinase | Neurodegeneration | Alzheimer's disease | Eukaryotic initiation factor-2α
Journal Article
Biochemical Journal, ISSN 0264-6021, 06/2004, Volume 380, Issue 2, pp. 523 - 531
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2011, Volume 108, Issue 12, pp. 5003 - 5008
Journal Article
Nature, ISSN 0028-0836, 05/2012, Volume 485, Issue 7399, pp. 507 - 511
The mechanisms leading to neuronal death in neurodegenerative disease are poorly understood. Many of these disorders, including Alzheimer's, Parkinson's and... 
UNFOLDED PROTEIN RESPONSE | TOXICITY IN-VIVO | ALZHEIMERS-DISEASE | ER STRESS | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | MICE | ENDOPLASMIC-RETICULUM STRESS | DYSFUNCTION | PRP | PROTEOSTASIS | Neurons - pathology | Neuroprotective Agents | Phosphorylation | Prions - genetics | Eukaryotic Initiation Factor-2 - chemistry | Neurodegenerative Diseases - etiology | PrPSc Proteins - analysis | Synapses - pathology | Thiourea - pharmacology | Phosphoproteins - metabolism | Repressor Proteins - analysis | PrPSc Proteins - metabolism | Synapses - metabolism | Phosphoproteins - analysis | Protein Folding - drug effects | Protein Phosphatase 1 - genetics | Eukaryotic Initiation Factor-2 - metabolism | Synaptic Transmission - drug effects | Cell Death - drug effects | PrPSc Proteins - toxicity | Neurons - drug effects | Repressor Proteins - metabolism | Prions - metabolism | Synapses - drug effects | Repressor Proteins - chemistry | Neurodegenerative Diseases - pathology | Mice, Inbred C57BL | Kaplan-Meier Estimate | Hippocampus - pathology | Prion Diseases - pathology | Neurodegenerative Diseases - metabolism | Hippocampus - cytology | Cinnamates - pharmacology | Eukaryotic Initiation Factor-2 - analysis | Hippocampus - metabolism | Protein Phosphatase 1 - metabolism | Animals | Prions - biosynthesis | Protein Biosynthesis - drug effects | Mice | Unfolded Protein Response - physiology | Thiourea - analogs & derivatives
Journal Article