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Oncogene, ISSN 0950-9232, 02/2008, Volume 27, Issue 8, pp. 1106 - 1113
There is currently substantial interest in the regulation of cell function by mammalian target of rapamycin ( mTOR), especially effects linked to the... 
4E-BP1 | Rapamycin | Cell cycle | Translation initiation | Cancer | MAMMALIAN TARGET | cell cycle | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | translation initiation | C-MYC | INTESTINAL EPITHELIAL-CELLS | CELL BIOLOGY | CAP-BINDING PROTEIN | AMINO-ACID | MESSENGER-RNA | ONCOLOGY | GENETICS & HEREDITY | FACTOR 4E | cancer | rapamycin | Cell Line | Transcription Factors - physiology | Antibiotics, Antineoplastic - pharmacology | Humans | Multiprotein Complexes | Eukaryotic Initiation Factor-4E - metabolism | Cyclin D1 - biosynthesis | Phosphoproteins - genetics | Breast Neoplasms - drug therapy | Sirolimus - pharmacology | Breast Neoplasms - metabolism | Mechanistic Target of Rapamycin Complex 1 | Proteins | Adaptor Proteins, Signal Transducing - physiology | Cyclin D1 - genetics | Signal Transduction - drug effects | Adaptor Proteins, Signal Transducing - deficiency | Phosphoproteins - deficiency | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | Signal Transduction - physiology | Phosphoproteins - physiology | TOR Serine-Threonine Kinases | Gene Expression Regulation, Neoplastic - physiology | Cellular proteins | Care and treatment | Physiological aspects | Genetic aspects | Cellular signal transduction | Research | Signal transduction | Eukaryotes | Cellular biology | Oncology | Breast cancer | Kinases | Gene expression
Journal Article
Journal Article
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Journal Article
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Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 11/2017, Volume 313, Issue 5, pp. C501 - C515
Journal Article
Lung Cancer, ISSN 0169-5002, 2010, Volume 70, Issue 3, pp. 329 - 334
Journal Article
Biochemical Journal, ISSN 0264-6021, 11/2014, Volume 463, Issue 3, pp. 413 - 427
The Vps34 (vacuolar protein sorting 34) class III PI3K (phosphoinositide 3-kinase) phosphorylates PtdIns (phosphatidylinositol) at endosomal membranes to... 
Mammalian target of rapamycin (mTOR) | Phosphoinositide 3-kinase (PI3K) | Protein kinase inhibitor | Signal transduction inhibitor | N-Myc downstream-regulated gene-1 (NDRG1) | Protein Structure, Tertiary | Cell Line | Phosphorylation | Class II Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol Phosphates - metabolism | Class I Phosphatidylinositol 3-Kinases - metabolism | Class II Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Humans | Inositol Polyphosphate 5-Phosphatases | Class III Phosphatidylinositol 3-Kinases - metabolism | Pyrimidines - pharmacology | Class I Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Endosomes - metabolism | Amino Acid Motifs | Aminopyridines - pharmacology | Hydrophobic and Hydrophilic Interactions | Protein Binding | Class III Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases | Phosphoric Monoester Hydrolases - metabolism | Protein-Serine-Threonine Kinases - metabolism | SGK3, serum- and glucocorticoid-regulated kinase-3 | signal transduction inhibitor | PI3K, phosphoinositide 3-kinase | ITC, isothermal titration calorimetry | SHIP1 | mTORC, mammalian target of rapamycin complex | EEA1, early endosome antigen 1 | INPP4B, inositol polyphosphate 4-phosphatase type II | TSC2, tuberous sclerosis complex 2 | phosphoinositide 3-kinase (PI3K) | HRP, horseradish peroxidase | PDK1, phosphoinositide-dependent kinase 1 | DMEM, Dulbecco's modified Eagle's medium | NDRG1, N-Myc downstream-regulated gene-1 | IGF, insulin-like growth factor | mTOR, mammalian target of rapamycin | IP1, inositol phosphate | 4E-BP1, eukaryotic initiation factor 4E-binding protein 1 | PX, Phox homology | mammalian target of rapamycin (mTOR) | Accelerated Publication | PH, pleckstrin homology | PtdIns, phosphatidylinositol | PRAS40, proline-rich Akt substrate 40 kDa | protein kinase inhibitor | 2, Src homology 2-domain-containing inositol phosphatase 1 | Vps34, vacuolar protein sorting 34 | VSV-G, vesicular stomatitis virus glycoprotein
Journal Article