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Neuron, ISSN 0896-6273, 2011, Volume 70, Issue 3, pp. 482 - 494
Transient receptor potential melastatin-3 (TRPM3) is a broadly expressed Ca -permeable nonselective cation channel. Previous work has demonstrated robust... 
TEMPERATURE | TRPV4 | CATION CHANNEL | ION-CHANNEL | PREGNENOLONE SULFATE | VANILLOID RECEPTOR-1 | COLD | CAPSAICIN-RECEPTOR | NEUROSCIENCES | MICE LACKING | EVOKED ACTIVATION | Hyperalgesia - chemically induced | Telemetry - methods | Calcium - metabolism | Capsaicin - pharmacology | Humans | Ganglia, Spinal - cytology | Transient Receptor Potential Channels - deficiency | Inflammation - metabolism | Time Factors | Behavior, Animal - drug effects | Sensory Receptor Cells - metabolism | Disease Models, Animal | Membrane Potentials - drug effects | Plant Oils - pharmacology | Trigeminal Ganglion - cytology | Mice, Knockout | Blood Glucose - drug effects | Patch-Clamp Techniques | Hyperalgesia - genetics | Transient Receptor Potential Channels - genetics | Gene Expression Regulation - radiation effects | TRPM Cation Channels - genetics | Blood Glucose - genetics | Mice | Inflammation - chemically induced | Mustard Plant | Pain Threshold - physiology | TRPM Cation Channels - deficiency | Membrane Potentials - genetics | Pregnenolone - adverse effects | Dose-Response Relationship, Drug | Transfection - methods | Bridged Bicyclo Compounds, Heterocyclic - therapeutic use | Freund's Adjuvant - adverse effects | Pain Threshold - drug effects | Nifedipine - pharmacology | Hot Temperature - adverse effects | Hyperalgesia - metabolism | Gene Expression Regulation - genetics | Mice, Inbred C57BL | Pain Measurement - drug effects | Calcium Channel Blockers - pharmacology | Pain Measurement - methods | Animals | Sensory Receptor Cells - drug effects | TRPM Cation Channels - antagonists & inhibitors | Hyperalgesia - drug therapy | TRPA1 Cation Channel | Inflammation - genetics | Acrylamides - therapeutic use | TRPM Cation Channels - metabolism | Cell Line, Transformed | Chemotherapy | Progesterone | Sulfates | Cancer | Heat | Behavior | Cold | Neurons | Rodents
Journal Article
Neuron, ISSN 0896-6273, 2009, Volume 63, Issue 1, pp. 27 - 39
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 12/2011, Volume 31, Issue 49, pp. 18155 - 18165
Global brain state dynamics regulate plasticity in local cortical circuits, but the underlying cellular and molecular mechanisms are unclear. Here, we... 
D-SERINE | NUCLEUS BASALIS | ACETYLCHOLINE | SOMATOSENSORY CORTEX | NEURAL ACTIVITY | RECEPTOR ACTIVATION | BARREL CORTEX | LONG-TERM POTENTIATION | RAT-BRAIN | NEUROSCIENCES | CEREBRAL-CORTEX | Thiazoles - metabolism | Action Potentials - genetics | Microdialysis - methods | Aniline Compounds - metabolism | Calcium Signaling - physiology | Fluoresceins - metabolism | Evoked Potentials, Somatosensory - drug effects | Neuronal Plasticity - drug effects | Male | Nerve Growth Factors - metabolism | Chromatography, High Pressure Liquid | Neuronal Plasticity - genetics | Evoked Potentials, Somatosensory - genetics | Neuronal Plasticity - physiology | Muscarinic Antagonists - pharmacology | Neurons - metabolism | Neurons - drug effects | Vibrissae - innervation | Action Potentials - drug effects | Physical Stimulation | Astrocytes - drug effects | Basal Nucleus of Meynert - physiology | S100 Calcium Binding Protein beta Subunit | Acetylcholine - pharmacology | Somatosensory Cortex - drug effects | Atropine - pharmacology | S100 Proteins - metabolism | Excitatory Amino Acid Antagonists - pharmacology | Cholinergic Agents - metabolism | Inositol 1,4,5-Trisphosphate Receptors - deficiency | Piperazines - pharmacology | Mice, Knockout | Somatosensory Cortex - physiology | Astrocytes - physiology | Animals | Calcium Signaling - drug effects | Serine - pharmacology | Afferent Pathways - physiology | Sulfonamides - metabolism | Mice | Calcium Signaling - genetics
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 08/2014, Volume 34, Issue 34, pp. 11385 - 11398
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 12/2009, Volume 29, Issue 48, pp. 15245 - 15257
Olfactory bulb (OB) interneurons are continuously renewed throughout an animal's lifespan. Despite extensive investigation of this phenomenon, little is known... 
FOREBRAIN | INHIBITION | MEMORY | DISCRIMINATION | BORN NEURONS | STIMULATED NEUROGENESIS | GAMMA-OSCILLATIONS | GRANULE CELLS | NEUROSCIENCES | NEWBORN NEURONS | BRAIN | Interneurons - physiology | Cytarabine - pharmacology | gamma-Aminobutyric Acid - metabolism | Male | Phosphopyruvate Hydratase - metabolism | Green Fluorescent Proteins - genetics | Nerve Net - drug effects | Nerve Net - physiology | Odorants | Smell - physiology | Time Factors | Exploratory Behavior - drug effects | Olfactory Perception - physiology | Discrimination (Psychology) - drug effects | Lysine - metabolism | Neurogenesis - drug effects | Bromodeoxyuridine - metabolism | Electric Stimulation - methods | Immunosuppressive Agents - pharmacology | Potassium Channel Blockers - pharmacology | Locomotion - drug effects | Olfactory Bulb - cytology | Lysine - analogs & derivatives | Mice, Inbred C57BL | Interneurons - drug effects | Biophysics | Hindlimb Suspension - methods | Association Learning - physiology | Association Learning - drug effects | Evoked Potentials - drug effects | Patch-Clamp Techniques | Ablation Techniques - methods | Animals | Recognition (Psychology) - drug effects | Sensory Thresholds - physiology | Discrimination (Psychology) - physiology | Mice | Locomotion - physiology | Inhibitory Postsynaptic Potentials - drug effects | Sensory Thresholds - drug effects
Journal Article
Journal of Neurophysiology, ISSN 0022-3077, 06/2012, Volume 107, Issue 12, pp. 3227 - 3234
Journal Article
Nature Neuroscience, ISSN 1097-6256, 11/2013, Volume 16, Issue 11, pp. 1671 - 1677
Neocortical activity can evoke sensory percepts, but the cellular mechanisms remain poorly understood. We trained mice to detect single brief whisker stimuli... 
PRIMARY SOMATOSENSORY CORTEX | VISUAL-CORTEX | AUDITORY-CORTEX | NEURAL ACTIVITY | CORTICAL MICROSTIMULATION | MOTOR CORTEX | SINGLE NEURON | NEUROSCIENCES | GABAERGIC NEURONS | LAYER 2/3 | BEHAVING MICE | Signal Detection, Psychological - physiology | Homeodomain Proteins - metabolism | Signal Detection, Psychological - drug effects | Parvalbumins - metabolism | Evoked Potentials - physiology | Male | Facial Nerve - physiology | Anesthetics, Local - pharmacology | Sensory Receptor Cells - physiology | Neurons - physiology | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Parvalbumins - genetics | Somatosensory Cortex - cytology | Tetrodotoxin - pharmacology | Neurons - drug effects | Membrane Potentials - drug effects | Physical Stimulation | Mice, Inbred C57BL | Valine - analogs & derivatives | Glutamate Decarboxylase - genetics | Mice, Transgenic | Excitatory Amino Acid Antagonists - pharmacology | Transcription Factors - genetics | Membrane Potentials - physiology | Homeodomain Proteins - genetics | Evoked Potentials - drug effects | Transcription Factors - metabolism | Animals | Vibrissae - physiology | Glutamate Decarboxylase - metabolism | Luminescent Proteins - genetics | Mice | Valine - pharmacology | Luminescent Proteins - metabolism | Usage | Membrane potentials | Physiological aspects | Sensory receptors | Models | Genetic aspects | Research
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 02/2009, Volume 29, Issue 8, pp. 2344 - 2354
Journal Article
Journal Article
Nature, ISSN 0028-0836, 02/2010, Volume 463, Issue 7282, pp. 769 - 774
Benzodiazepines are widely used in clinics and for recreational purposes, but will lead to addiction in vulnerable individuals. Addictive drugs increase the... 
CELLS | EVOKED SYNAPTIC PLASTICITY | ACID | RAT | ABUSE | MULTIDISCIPLINARY SCIENCES | IN-VIVO | GABA(B) RECEPTORS | MIDBRAIN DOPAMINERGIC-NEURONS | MODULATION | VENTRAL TEGMENTAL AREA | gamma-Aminobutyric Acid - metabolism | Midazolam - administration & dosage | Neuronal Plasticity - drug effects | Substrate Specificity | Electric Conductivity | Ventral Tegmental Area - cytology | Receptors, GABA-A - deficiency | Midazolam - adverse effects | Neurons - metabolism | Behavior, Addictive - physiopathology | Neurons - drug effects | Action Potentials - drug effects | Dopamine - metabolism | Receptors, AMPA - metabolism | Ventral Tegmental Area - drug effects | Behavior, Addictive - pathology | Benzodiazepines - pharmacology | Morphine - pharmacology | Administration, Oral | Mice, Inbred C57BL | Interneurons - drug effects | Inhibitory Postsynaptic Potentials - physiology | Organ Specificity | Animals | Interneurons - metabolism | Behavior, Addictive - chemically induced | Models, Biological | Receptors, GABA-A - genetics | Ventral Tegmental Area - metabolism | Benzodiazepines - administration & dosage | Benzodiazepines - adverse effects | Glutamic Acid - metabolism | Mice | Receptors, GABA-A - metabolism | In Vitro Techniques | Midazolam - pharmacology | Inhibitory Postsynaptic Potentials - drug effects | Usage | Receptors | Neurons | Analysis | GABA | Research | Ventral tegmental area | Benzodiazepines | Proteins | Drugs | Addictions | Polyamines | Addictive behaviors
Journal Article
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 04/2013, Volume 33, Issue 16, pp. 6990 - 7002
The impact of spontaneous neurotransmission on neuronal plasticity remains poorly understood. Here, we show that acute suppression of spontaneous NMDA... 
LONG-TERM | DEPRESSION | TRANSMISSION | ACID | INDUCTION | RELEASE | RECEPTORS | GLUR2 | NEUROSCIENCES | DENDRITIC PROTEIN-SYNTHESIS | KETAMINE | Electric Stimulation | Locomotion - genetics | Synaptic Transmission - physiology | Evoked Potentials - physiology | Excitatory Postsynaptic Potentials - drug effects | Brain-Derived Neurotrophic Factor - deficiency | Elongation Factor 2 Kinase - deficiency | Exploratory Behavior - physiology | Neural Inhibition - physiology | Neuronal Plasticity - physiology | Time Factors | Exploratory Behavior - drug effects | Tetrodotoxin - pharmacology | Excitatory Postsynaptic Potentials - genetics | Receptors, AMPA - metabolism | Inhibition (Psychology) | Locomotion - drug effects | Animals, Newborn | Gene Expression Regulation - genetics | Synapses - physiology | Enzyme Inhibitors - pharmacology | Rats | Sodium Channel Blockers - pharmacology | Excitatory Amino Acid Agonists - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Biophysics | Hippocampus - cytology | Rats, Sprague-Dawley | Feeding Behavior - physiology | Feeding Behavior - drug effects | GABA Antagonists - pharmacology | Mice, Knockout | Gene Expression Regulation - drug effects | Swimming - physiology | Patch-Clamp Techniques | Animals | Evoked Potentials - genetics | Analysis of Variance | Picrotoxin - pharmacology | Glutamic Acid - metabolism | Mice | Hippocampus - physiology | In Vitro Techniques | Ketamine - pharmacology | Neural Inhibition - drug effects
Journal Article