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Neuropharmacology, ISSN 0028-3908, 03/2013, Volume 66, pp. 158 - 169
Group III metabotropic glutamate (mGlu) receptors are localized in presynaptic terminals within basal ganglia (BG) circuitry that become hyperactive due to... 
Striatum | Basal ganglia | Akinesia | Rat | Lu AF21934 | l-DOPA-induced dyskinesia | Electrophysiology | HIGH-FREQUENCY STIMULATION | NEUROLOGICAL DISEASES | NEUROSCIENCES | RAT MODEL | STRIATAL SYNAPTIC PLASTICITY | MEDIATED MODULATION | SUBTHALAMIC NUCLEUS | UNILATERAL 6-HYDROXYDOPAMINE LESIONS | PHARMACOLOGY & PHARMACY | DEEP BRAIN-STIMULATION | L-DOPA-induced dyskinesia | MOLECULAR-MECHANISMS | Anilides - therapeutic use | Catalepsy - drug therapy | Synaptic Transmission - physiology | Excitatory Amino Acid Agonists - therapeutic use | Receptors, Metabotropic Glutamate - physiology | Male | Aminobutyrates - pharmacology | Anilides - pharmacokinetics | Parkinson Disease - drug therapy | Oxidopamine | Aminobutyrates - therapeutic use | Excitatory Postsynaptic Potentials - drug effects | Dose-Response Relationship, Drug | Excitatory Postsynaptic Potentials - physiology | Haloperidol - antagonists & inhibitors | Allosteric Regulation - physiology | Dyskinesia, Drug-Induced - drug therapy | Catalepsy - chemically induced | Synaptic Transmission - drug effects | Haloperidol - pharmacology | Disease Models, Animal | Allosteric Regulation - drug effects | Aminobutyrates - agonists | Levodopa - pharmacology | Cyclohexanecarboxylic Acids - therapeutic use | Phosphinic Acids - agonists | Levodopa - therapeutic use | Phosphinic Acids - therapeutic use | Rats | Excitatory Amino Acid Agonists - pharmacology | Rats, Sprague-Dawley | Drug Synergism | Animals | Cyclohexanecarboxylic Acids - pharmacology | Levodopa - adverse effects | Phosphinic Acids - pharmacology | Anilides - pharmacology | Excitatory Amino Acid Agonists - pharmacokinetics | Cyclohexanecarboxylic Acids - pharmacokinetics | Receptors, Metabotropic Glutamate - agonists | Receptors, Metabotropic Glutamate - antagonists & inhibitors | Physiological aspects | Phenols | Amino acids | Parkinson's disease | Glutamate | Drug therapy | 6-Hydroxydopamine | Phosphinic Acids | Excitatory Amino Acid Agonists | Allosteric Regulation | Catalepsy | Haloperidol | Aminobutyrates | Cellular Biology | Synaptic Transmission | Receptors, Metabotropic Glutamate | Parkinson Disease | Anilides | Life Sciences | Excitatory Postsynaptic Potentials | Cyclohexanecarboxylic Acids | Dyskinesia, Drug-Induced | Levodopa
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 04/2013, Volume 38, Issue 5, pp. 729 - 742
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 07/2000, Volume 43, Issue 14, pp. 2609 - 2645
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 04/2013, Volume 38, Issue 5, pp. 743 - 752
The NMDA-receptor antagonist ketamine has proven efficient in reducing symptoms of suicidality, although the mechanisms explaining this effect have not been... 
cytokine | quinolinic acid | depression | glutamate | suicide | PSYCHIATRY | RESISTANT DEPRESSION | ADD-ON TRIAL | D-ASPARTATE ANTAGONIST | NEUROSCIENCES | HIPPOCAMPAL VOLUME | EMERGENCY-DEPARTMENT | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | KYNURENIC ACID | MAJOR DEPRESSIVE DISORDER | Encephalitis - psychology | Excitatory Amino Acid Agonists - cerebrospinal fluid | Kynurenine - cerebrospinal fluid | Quinolinic Acid - cerebrospinal fluid | Excitatory Amino Acid Agonists - therapeutic use | Follow-Up Studies | Somatosensory Disorders - complications | Spinal Puncture | Humans | Middle Aged | Male | Mental Disorders - complications | Kynurenic Acid - cerebrospinal fluid | Mental Disorders - psychology | Young Adult | Psychiatric Status Rating Scales | Tritium - cerebrospinal fluid | Encephalitis - cerebrospinal fluid | Suicide - psychology | Adult | Female | Aged | Retrospective Studies | Interleukin-6 - metabolism | Brain | Glutamic acid | Glutamic acid receptors (ionotropic) | Depression | Mass spectroscopy | N-Methyl-D-aspartic acid receptors | Glutamic acid receptors | Inflammation | Cerebrospinal fluid | High-performance liquid chromatography | Suicide | Interleukin 6 | Gas chromatography | Ketamine | Glutamatergic transmission | Kynurenic acid | Quinolinic acid | Neurotransmission | Original | Medical and Health Sciences | Medicin och hälsovetenskap | MEDICIN | MEDICINE
Journal Article
Neuropharmacology, ISSN 0028-3908, 01/2013, Volume 64, pp. 337 - 346
Cognitive impairment, in particular of attention and memory, is often reported by patients suffering from major depressive disorder (MDD) and deficits in... 
Cognitive flexibility | Neuronal plasticity | Major depression | Hippocampus | mGlu2 | EXECUTIVE DYSFUNCTION | ANTERIOR CINGULATE | CHRONIC MILD STRESS | BIPOLAR DISORDER | NEUROSCIENCES | PREFRONTAL CORTEX | NEUROPSYCHOLOGICAL PERFORMANCE | TREATMENT RESPONSE | PHARMACOLOGY & PHARMACY | RECOGNITION MEMORY | GABAERGIC NEURONS | WORKING-MEMORY | Excitatory Amino Acid Antagonists - therapeutic use | Excitatory Amino Acid Agonists - therapeutic use | Cognition Disorders - chemically induced | Depressive Disorder, Major - metabolism | Humans | Receptors, Metabotropic Glutamate - metabolism | Hippocampus - drug effects | Molecular Targeted Therapy | Cognition Disorders - prevention & control | Cognition Disorders - etiology | Antidepressive Agents - pharmacology | GABAergic Neurons - metabolism | Depressive Disorder, Major - drug therapy | Depressive Disorder, Major - physiopathology | Nerve Tissue Proteins - antagonists & inhibitors | Nerve Tissue Proteins - agonists | Interneurons - drug effects | GABAergic Neurons - drug effects | Nootropic Agents - therapeutic use | Excitatory Amino Acid Agonists - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Antidepressive Agents - therapeutic use | Nerve Tissue Proteins - metabolism | Hippocampus - metabolism | Animals | Interneurons - metabolism | Excitatory Amino Acid Agonists - adverse effects | Antidepressive Agents - adverse effects | Receptors, Metabotropic Glutamate - agonists | Nootropic Agents - pharmacology | Receptors, Metabotropic Glutamate - antagonists & inhibitors | Glutamate | Antidepressants | Health aspects | Major depressive disorder
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 03/2007, Volume 27, Issue 11, pp. 2846 - 2857
Journal Article
Journal Article
Trends in Molecular Medicine, ISSN 1471-4914, 2011, Volume 17, Issue 12, pp. 689 - 698
Although early clinical observations implicated dopamine dysfunction in the neuropathology of schizophrenia, accumulating evidence suggests that multiple... 
Pathology | ANTIPSYCHOTIC-LIKE ACTIVITY | MEDICINE, RESEARCH & EXPERIMENTAL | POSITIVE ALLOSTERIC MODULATOR | IN-VIVO ACTIVITY | NMDA RECEPTOR | GLYT1 INHIBITORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | RAT BEHAVIORAL-MODELS | MUSCARINIC ACETYLCHOLINE-RECEPTORS | PREFRONTAL CORTEX | CELL BIOLOGY | N-DESMETHYLCLOZAPINE | METHYL-D-ASPARTATE | Glycine Plasma Membrane Transport Proteins - metabolism | Schizophrenia - metabolism | Excitatory Amino Acid Agonists - therapeutic use | Humans | Muscarinic Agonists - therapeutic use | Receptors, N-Methyl-D-Aspartate - metabolism | Receptors, Muscarinic - metabolism | Receptors, Metabotropic Glutamate - metabolism | Antipsychotic Agents - chemical synthesis | Muscarinic Agonists - chemical synthesis | Synapses - metabolism | Antipsychotic Agents - therapeutic use | Schizophrenia - physiopathology | Excitatory Amino Acid Agonists - chemical synthesis | Synaptic Transmission - drug effects | Synapses - drug effects | Muscarinic Agonists - administration & dosage | Rats | Mice, Knockout | Antipsychotic Agents - administration & dosage | Excitatory Amino Acid Agonists - administration & dosage | Animals | Receptors, N-Methyl-D-Aspartate - agonists | Ligands | Mice | Schizophrenia - drug therapy | Receptors, Metabotropic Glutamate - agonists | Glycine Plasma Membrane Transport Proteins - antagonists & inhibitors | Schizophrenia | Glutamate | Methyl aspartate | Dopamine | Acetylcholine receptors (muscarinic) | Mental disorders | Glutamic acid receptors (ionotropic) | Neuropathology | N-Methyl-D-aspartic acid receptors | Antagonists | Glutamic acid receptors | Signal transduction | Allosteric properties | Neurotransmitters | Reviews | Glycine transporter | Glutamatergic transmission | Receptor mechanisms | Glutamic acid receptors (metabotropic) | Synapses
Journal Article