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Journal of Immunology, ISSN 0022-1767, 09/2015, Volume 195, Issue 5, pp. 1939 - 1943
Detection of intracellular DNA triggers activation of the stimulator of IFN genes dependent IFN-stimulatory DNA (ISD) pathway, which is essential for antiviral... 
CYCLIC GMP-AMP | INTRACELLULAR DNA | LUPUS | DENDRITIC CELLS | GENE | DNA EXONUCLEASE TREX1 | CYTOSOLIC DNA | INNATE IMMUNE SENSOR | MUTATIONS | IMMUNOLOGY | RETROVIRUSES | Nucleotides, Cyclic - metabolism | Phosphoproteins - immunology | Exodeoxyribonucleases - immunology | Interferon-beta - immunology | Nervous System Malformations - immunology | Gene Expression - drug effects | Autoantibodies - blood | Humans | Immunoblotting | Interferons - immunology | Phosphoproteins - metabolism | Inflammation - metabolism | Nervous System Malformations - metabolism | Autoimmune Diseases of the Nervous System - genetics | Gene Expression - immunology | Interferon-beta - genetics | Exodeoxyribonucleases - genetics | Nucleotidyltransferases - metabolism | Autoimmune Diseases of the Nervous System - metabolism | Nervous System Malformations - genetics | Macrophages - immunology | Disease Models, Animal | Fibroblasts - metabolism | Interferons - pharmacology | Mice, Inbred C57BL | Cells, Cultured | Inflammation - immunology | Phosphoproteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Mice, Knockout | Autoimmune Diseases of the Nervous System - immunology | Autoantibodies - immunology | Macrophages - metabolism | Animals | Interferon-beta - metabolism | Embryo, Mammalian - cytology | Fibroblasts - drug effects | Exodeoxyribonucleases - metabolism | Inflammation - genetics | Nucleotidyltransferases - genetics | Fibroblasts - immunology | Macrophages - drug effects | Nucleotidyltransferases - immunology | Nucleotides, Cyclic - immunology | Index Medicus | Abridged Index Medicus
Journal Article
Journal of immunology (Baltimore, Md, ISSN 0022-1767, 2015, Volume 194, Issue 8, pp. 3623 - 3633
Aicardi-Goutières syndrome (AGS) is a monogenic inflammatory encephalopathy caused by mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, ADAR1, or MDA5.... 
INTERFERON-ALPHA | ACTIVATION | TREX1 | DNA | MUTATIONS | IMMUNOLOGY | SAMHD1 | RIBONUCLEOTIDES | ASTROCYTES | EXPRESSION | CEREBRAL VASCULOPATHY | Phosphoproteins - immunology | RNA-Binding Proteins - genetics | Exodeoxyribonucleases - immunology | Nervous System Malformations - immunology | Humans | Astrocytes - pathology | SAM Domain and HD Domain-Containing Protein 1 | Monomeric GTP-Binding Proteins - immunology | Autoimmune Diseases of the Nervous System - pathology | Autoimmune Diseases of the Nervous System - mortality | Ribonuclease H - immunology | Neural Stem Cells - immunology | Astrocytes - immunology | Interferon-alpha - genetics | Autoimmune Diseases of the Nervous System - genetics | HEK293 Cells | Exodeoxyribonucleases - genetics | Nervous System Malformations - genetics | Cytokines - genetics | Cytokines - immunology | Ribonuclease H - genetics | Adenosine Deaminase - genetics | Nervous System Malformations - pathology | RNA-Binding Proteins - immunology | Gene Silencing | Monomeric GTP-Binding Proteins - genetics | Phosphoproteins - genetics | Neural Stem Cells - pathology | Interferon-alpha - immunology | Endothelial Cells - immunology | Autoimmune Diseases of the Nervous System - immunology | Nervous System Malformations - mortality | Mutation | Endothelial Cells - pathology | Adenosine Deaminase - immunology | Index Medicus | Abridged Index Medicus
Journal Article
Nature communications, ISSN 2041-1723, 06/2017, Volume 8, Issue 1, pp. 15618 - 15618
Journal Article
Journal of Immunology, ISSN 0022-1767, 11/2014, Volume 193, Issue 9, pp. 4634 - 4642
Journal Article
Immunity, ISSN 1074-7613, 08/2016, Volume 45, Issue 2, pp. 255 - 266
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 2017, Volume 45, Issue 8, pp. 4619 - 4631
Journal Article
Journal Article
Journal of Autoimmunity, ISSN 0896-8411, 2017, Volume 81, pp. 13 - 23
Journal Article
15.