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Cell, ISSN 0092-8674, 04/2011, Volume 145, Issue 1, pp. 54 - 66
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 511, Issue 7509, pp. 362 - 365
Journal Article
Molecular Cell, ISSN 1097-2765, 09/2012, Volume 47, Issue 6, pp. 980 - 986
Journal Article
Journal of Immunology, ISSN 0022-1767, 11/2014, Volume 193, Issue 9, pp. 4634 - 4642
Journal Article
Molecular Cell, ISSN 1097-2765, 05/2013, Volume 50, Issue 4, pp. 589 - 600
Replication protein A (RPA) is an essential eukaryotic single-stranded DNA binding protein with a central role in DNA metabolism. RPA directly participates in... 
POLYMERASE-DELTA | DAMAGE CHECKPOINT | BIOCHEMISTRY & MOLECULAR BIOLOGY | YEAST RAD52 PROTEIN | REPLICATION-PROTEIN-A | DOUBLE-STRAND BREAKS | HOMOLOGOUS RECOMBINATION | CHECKPOINT ACTIVATION | PRESYNAPTIC COMPLEX-FORMATION | SACCHAROMYCES-CEREVISIAE | MEIOTIC RECOMBINATION | CELL BIOLOGY | DNA, Fungal - genetics | RecQ Helicases - metabolism | Saccharomyces cerevisiae - genetics | RecQ Helicases - genetics | DNA, Fungal - chemistry | DNA Breaks, Double-Stranded | DNA-Directed DNA Polymerase - genetics | DNA, Single-Stranded - genetics | Saccharomyces cerevisiae - metabolism | Replication Protein A - genetics | Endodeoxyribonucleases - metabolism | Exodeoxyribonucleases - genetics | Nucleic Acid Conformation | DNA Helicases - genetics | Rad51 Recombinase - metabolism | Rad51 Recombinase - genetics | DNA, Single-Stranded - metabolism | Replication Protein A - metabolism | Saccharomyces cerevisiae Proteins - genetics | Blotting, Western | DNA, Single-Stranded - chemistry | DNA Helicases - metabolism | Endodeoxyribonucleases - genetics | DNA Repair | DNA, Fungal - metabolism | Exodeoxyribonucleases - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Protein Binding | Luminescent Proteins - genetics | Models, Genetic | DNA-Directed DNA Polymerase - metabolism | Mutation | Microscopy, Fluorescence | Luminescent Proteins - metabolism | Physiological aspects | DNA synthesis | Surgery | Genomics | DNA | Protein binding
Journal Article
Journal Article
Journal of Immunology, ISSN 0022-1767, 09/2015, Volume 195, Issue 5, pp. 1939 - 1943
Detection of intracellular DNA triggers activation of the stimulator of IFN genes dependent IFN-stimulatory DNA (ISD) pathway, which is essential for antiviral... 
CYCLIC GMP-AMP | INTRACELLULAR DNA | LUPUS | DENDRITIC CELLS | GENE | DNA EXONUCLEASE TREX1 | CYTOSOLIC DNA | INNATE IMMUNE SENSOR | MUTATIONS | IMMUNOLOGY | RETROVIRUSES | Nucleotides, Cyclic - metabolism | Phosphoproteins - immunology | Exodeoxyribonucleases - immunology | Interferon-beta - immunology | Nervous System Malformations - immunology | Gene Expression - drug effects | Autoantibodies - blood | Humans | Immunoblotting | Interferons - immunology | Phosphoproteins - metabolism | Inflammation - metabolism | Nervous System Malformations - metabolism | Autoimmune Diseases of the Nervous System - genetics | Gene Expression - immunology | Interferon-beta - genetics | Exodeoxyribonucleases - genetics | Nucleotidyltransferases - metabolism | Autoimmune Diseases of the Nervous System - metabolism | Nervous System Malformations - genetics | Macrophages - immunology | Disease Models, Animal | Fibroblasts - metabolism | Interferons - pharmacology | Mice, Inbred C57BL | Cells, Cultured | Inflammation - immunology | Phosphoproteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Mice, Knockout | Autoimmune Diseases of the Nervous System - immunology | Autoantibodies - immunology | Macrophages - metabolism | Animals | Interferon-beta - metabolism | Embryo, Mammalian - cytology | Fibroblasts - drug effects | Exodeoxyribonucleases - metabolism | Inflammation - genetics | Nucleotidyltransferases - genetics | Fibroblasts - immunology | Macrophages - drug effects | Nucleotidyltransferases - immunology | Nucleotides, Cyclic - immunology
Journal Article
Molecular Cell, ISSN 1097-2765, 09/2017, Volume 67, Issue 5, pp. 867 - 881.e7
Journal Article
Cell, ISSN 0092-8674, 2007, Volume 130, Issue 5, pp. 824 - 836
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2013, Volume 110, Issue 19, pp. 7720 - 7725
Journal Article
Journal of Cell Science, ISSN 0021-9533, 06/2013, Volume 126, Issue 12, pp. 2656 - 2667
In eukaryotes, mRNA export involves many evolutionarily conserved factors that carry the nascent transcript to the nuclear pore complex (NPC). The THO/TREX... 
AMEX | mRNA export | NXF1 | Transcription | Nuclear pore complex | THO/TREX | TREX-2 | MESSENGER-RNA EXPORT | BINDING PROTEIN | PHOTORECEPTOR CELLS | SAGA | CELL BIOLOGY | STRUCTURAL BASIS | FUNCTIONAL COMPONENT | PROTEOMIC ANALYSIS | INTERACTION PLATFORM | LIVING CELLS | RNA-Binding Proteins - genetics | Acetyltransferases - metabolism | Humans | Intracellular Signaling Peptides and Proteins - metabolism | Phosphoproteins - metabolism | RNA, Messenger - metabolism | Acetyltransferases - genetics | Nuclear Pore Complex Proteins - genetics | Cell Nucleus - metabolism | Exodeoxyribonucleases - genetics | Nuclear Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | Proto-Oncogene Proteins - metabolism | RNA Transport | Nuclear Pore Complex Proteins - metabolism | RNA, Messenger - genetics | Nuclear Pore - genetics | Nuclear Proteins - metabolism | Proto-Oncogene Proteins - genetics | Phosphoproteins - genetics | Transcription Factors - genetics | Nuclear Pore - metabolism | Nucleocytoplasmic Transport Proteins - genetics | Transcription Factors - metabolism | Transcription, Genetic - physiology | Nucleocytoplasmic Transport Proteins - metabolism | Cell Nucleus - genetics | Exodeoxyribonucleases - metabolism | Cell Line, Tumor | HeLa Cells | Transcription, Genetic - genetics | RNA-Binding Proteins - metabolism
Journal Article