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1. Full Text mRNA Deadenylation Is Coupled to Translation Rates by the Differential Activities of Ccr4-Not Nucleases
by Webster, Michael W and Chen, Ying-Hsin and Stowell, James A.W and Alhusaini, Najwa and Sweet, Thomas and Graveley, Brenton R and Coller, Jeff and Passmore, Lori A
Molecular cell, ISSN 1097-2765, 06/2018, Volume 70, Issue 6, pp. 1089 - 1100.e8
poly(A) tail | exonuclease | RNA binding protein | translation | deadenylation | gene expression | mRNA decay | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | RNA-Binding Proteins - genetics | Exoribonucleases - genetics | Schizosaccharomyces pombe Proteins - genetics | RNA, Messenger - genetics | Poly(A)-Binding Protein I - metabolism | Transcriptome | Cytoplasm - metabolism | Endonucleases - metabolism | Transcription Factors - genetics | RNA Stability | RNA, Messenger - metabolism | Ribonucleases - metabolism | RNA, Fungal - metabolism | Schizosaccharomyces - genetics | Transcription Factors - metabolism | Schizosaccharomyces - metabolism | Poly A - metabolism | Polyadenylation | Schizosaccharomyces pombe Proteins - metabolism | Schizosaccharomyces - enzymology | RNA, Fungal - genetics | Exoribonucleases - metabolism | RNA-Binding Proteins - metabolism | Messenger RNA | Codon | Developmental biology | Exonucleases | DNA binding proteins | Molecular biology | Genetic translation | Protein binding | Index Medicus
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2. Full Text The 3′ end formation in small RNAs
by Perumal, Karthika and Reddy, Ram
Gene expression, ISSN 1052-2166, 2002, Volume 10, Issue 1-2, pp. 59 - 78
3′ Uridylation | 3′ End formation | 3′ Adenylation | Small RNAs | Gastroenterology & Hepatology | Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | RNA 3' End Processing - physiology | Saccharomyces cerevisiae - genetics | Humans | Multienzyme Complexes - metabolism | Eukaryotic Cells - metabolism | RNA, Ribosomal, 5.8S - metabolism | RNA Polymerase II - metabolism | RNA Caps - metabolism | Spliceosomes - metabolism | Telomerase - metabolism | Transcription, Genetic | Telomere - metabolism | Exonucleases - metabolism | RNA - metabolism | RNA Processing, Post-Transcriptional | RNA Polymerase III - metabolism | RNA, Fungal - metabolism | RNA, Small Nucleolar - chemistry | Animals | Prokaryotic Cells - metabolism | Escherichia coli - genetics | Polyadenylation | Saccharomyces cerevisiae Proteins - metabolism | RNA, Small Nuclear - chemistry | Uridine - metabolism | Mice | Models, Genetic | Index Medicus
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3. Full Text Origins and activities of the eukaryotic exosome
by Lykke-Andersen, Søren and Brodersen, Ditiev E and Jensen, Torben Heick
Journal of cell science, ISSN 0021-9533, 05/2009, Volume 122, Issue 10, pp. 1487 - 1494
RNA exosome | Exosome structure | Exosome function | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Eukaryotic Cells - enzymology | Exosomes - metabolism | Polynucleotide Adenylyltransferase - metabolism | RNA Helicases - metabolism | RNA Processing, Post-Transcriptional | Humans | Ribosomes - metabolism | Cytoplasm - metabolism | Eukaryotic Cells - metabolism | Endonucleases - metabolism | RNA, Messenger - metabolism | RNA, Fungal - metabolism | Animals | Prokaryotic Cells - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Exosomes - enzymology | Transcription, Genetic | Exonucleases - metabolism | Exosome Multienzyme Ribonuclease Complex | RNA, Bacterial - metabolism | RNA - metabolism | Index Medicus
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4. Full Text A role for the Perlman syndrome exonuclease Dis3l2 in the Lin28-let-7 pathway
by Chang, Hao-Ming and Triboulet, Robinson and Thornton, James E and Gregory, Richard I
Nature (London), ISSN 0028-0836, 2013, Volume 497, Issue 7448, pp. 244 - 248
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Uridine Monophosphate - metabolism | Embryonic Stem Cells - metabolism | Fetal Macrosomia - metabolism | Wilms Tumor - genetics | Humans | Substrate Specificity | MicroRNAs - metabolism | Ribonucleases - metabolism | HEK293 Cells | RNA Precursors - metabolism | Exonucleases - metabolism | Wilms Tumor - metabolism | RNA Processing, Post-Transcriptional | Cells, Cultured | Fetal Macrosomia - genetics | Fetal Macrosomia - enzymology | RNA Precursors - genetics | RNA Stability | Animals | Wilms Tumor - enzymology | Uridine Monophosphate - analogs & derivatives | Wilms Tumor - etiology | Mice | MicroRNAs - genetics | Exoribonucleases - metabolism | RNA-Binding Proteins - metabolism | Proteins | Cloning | Cytoplasm | Cell cycle | Index Medicus | uridylation | let-7 | microRNA (miRNA) | exonuclease | Lin28 | Lin-28 | Embryonic Stem Cells | TUTase | Dis3l2
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5. Full Text SAMHD1 acts at stalled replication forks to prevent interferon induction
by Coquel, Flavie and Silva, Maria-Joao and Técher, Hervé and Zadorozhny, Karina and Sharma, Sushma and Nieminuszczy, Jadwiga and Mettling, Clément and Dardillac, Elodie and Barthe, Antoine and Schmitz, Anne-Lyne and Promonet, Alexy and Cribier, Alexandra and Sarrazin, Amélie and Niedzwiedz, Wojciech and Lopez, Bernard and Costanzo, Vincenzo and Krejci, Lumir and Chabes, Andrei and Benkirane, Monsef and Lin, Yea-Lih and Pasero, Philippe
Nature (London), ISSN 0028-0836, 05/2018, Volume 557, Issue 7703, pp. 57 - 61
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | SAM Domain and HD Domain-Containing Protein 1 - metabolism | RecQ Helicases - metabolism | DNA, Single-Stranded - metabolism | Humans | DNA Replication | Inflammation - immunology | SAM Domain and HD Domain-Containing Protein 1 - deficiency | Interferon Type I - immunology | Checkpoint Kinase 1 - metabolism | Inflammation - metabolism | HEK293 Cells | Interferon Type I - metabolism | Cytosol - metabolism | Inflammation - prevention & control | Membrane Proteins - metabolism | HeLa Cells | Nucleotidyltransferases - metabolism | MRE11 Homologue Protein - metabolism | Physiological aspects | DNA replication | Interferon | Observations | Cytokines | Single-stranded DNA | DNA damage | CHK1 protein | Genomes | Kinases | DNA repair | Cytosol | Replication forks | DNA biosynthesis | Exonuclease | Microscopy | MRE11 protein | Replication | Mutation | Deoxyribonucleic acid--DNA | Cellular stress response | Cancer | Index Medicus | Life Sciences | Genetics
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6. Full Text Regulation of the p53-MDM2 pathway by 14-3-3 sigma and other proteins
by Lee, Mong-Hong and Lozano, Guillermina
Seminars in cancer biology, ISSN 1044-579X, 06/2006, Volume 16, Issue 3, pp. 225 - 234
Life Sciences & Biomedicine | Oncology | Science & Technology | Exoribonucleases | Humans | Neoplasm Proteins - metabolism | Tripartite Motif-Containing Protein 28 | DNA-Binding Proteins - metabolism | Exonucleases - genetics | Biomarkers, Tumor - metabolism | Exonucleases - metabolism | Neoplasm Proteins - genetics | Proto-Oncogene Proteins c-akt - metabolism | Gene Expression Regulation, Neoplastic - physiology | Proto-Oncogene Proteins c-mdm2 - metabolism | Protein-Serine-Threonine Kinases - metabolism | Repressor Proteins - metabolism | Proto-Oncogene Proteins - metabolism | Endopeptidases - metabolism | Tumor Suppressor Proteins - metabolism | Cell Cycle Proteins - metabolism | Tumor Suppressor Protein p53 - metabolism | Ubiquitin-Protein Ligases - metabolism | PTEN Phosphohydrolase - metabolism | Neoplasm Proteins - chemistry | Ataxia Telangiectasia Mutated Proteins | Exonucleases - chemistry | Animals | Signal Transduction - physiology | 14-3-3 Proteins | Biomarkers, Tumor - genetics | Proteasome Endopeptidase Complex - metabolism | Biomarkers, Tumor - chemistry | Tumor Suppressor Protein p14ARF - metabolism | Ubiquitin Thiolesterase | Ubiquitin-Specific Peptidase 7 | Protein Binding - physiology | Index Medicus
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7. Full Text Metabolism and Disposition of Volanesorsen, a 2 '-O-(2 methoxyethyl) Antisense Oligonucleotide, Across Species
by Post, Noah and Yu, Rosie and Greenlee, Sarah and Gaus, Hans and Hurh, Eunju and Matson, John and Wang, Yanfeng
Drug metabolism and disposition, ISSN 0090-9556, 10/2019, Volume 47, Issue 10, pp. 1164 - 1173
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Urine | Excretion | Drug delivery systems | Antisense oligonucleotides | Monkeys | Triglycerides | Nucleotides | Metabolism | Population decline | Plasma proteins | Exonuclease | Metabolites | Mice | Species | Index Medicus
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8. Full Text Myg1 exonuclease couples the nuclear and mitochondrial translational programs through RNA processing
by Grover, Ritika and Burse, Shaunak A and Shankrit, Shambhavi and Aggarwal, Ayush and Kirty, Kritika and Narta, Kiran and Srivastav, Rajpal and Ray, Ashwini Kumar and Malik, Garima and Vats, Archana and Motiani, Rajender K and Thukral, Lipi and Roy, Soumya Sinha and Bhattacharya, Sudha and Sharma, Rakesh and Natarajan, Krishnamurthy and Mukerji, Mitali and Pandey, Rajesh and Gokhale, Rajesh S and Natarajan, Vivek T
Nucleic acids research, ISSN 0305-1048, 06/2019, Volume 47, Issue 11, pp. 5852 - 5866
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Protein Biosynthesis | Endoribonucleases - metabolism | Saccharomyces cerevisiae - genetics | Humans | RNA, Ribosomal - metabolism | Ribosomes - metabolism | Nuclear Proteins - metabolism | Mitochondria - metabolism | Sequence Analysis, DNA | Saccharomyces cerevisiae - metabolism | Animals | Cell Nucleus - metabolism | Proteins - metabolism | Mitochondria - genetics | Mitochondrial Proteins - metabolism | Cell Nucleolus - metabolism | Mice | Exonucleases - metabolism | Vitiligo - genetics | Quality Control | Index Medicus | Nucleic Acid Enzymes
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9. Full Text Argonaute and triman generate dicer-independent prirnas and mature siRNAs to initiate heterochromatin formation
by Marasovic, Mirela and Zocco, Manuel and Halic, Mario
Molecular cell, ISSN 1097-2765, 10/2013, Volume 52, Issue 2, pp. 173 - 183
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | RNA, Small Interfering - genetics | Endoribonucleases - genetics | Exoribonucleases - genetics | Molecular Sequence Data | Centromere - metabolism | Schizosaccharomyces - genetics | Heterochromatin - metabolism | RNA Interference | Exonucleases - genetics | Schizosaccharomyces pombe Proteins - metabolism | Exosome Multienzyme Ribonuclease Complex - metabolism | RNA Precursors - metabolism | RNA, Fungal - genetics | Exonucleases - metabolism | Exosome Multienzyme Ribonuclease Complex - genetics | Amino Acid Sequence | Argonaute Proteins - metabolism | Argonaute Proteins - genetics | Schizosaccharomyces pombe Proteins - genetics | Endoribonucleases - metabolism | Electrophoresis, Polyacrylamide Gel | RNA Precursors - genetics | Blotting, Western | RNA, Fungal - metabolism | Sequence Homology, Amino Acid | Schizosaccharomyces - metabolism | Heterochromatin - genetics | Centromere - genetics | Protein Binding | Models, Genetic | Mutation | Exoribonucleases - metabolism | RNA, Small Interfering - metabolism | RNA | Genomics | Index Medicus
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10. Full Text Keratin 17 Expression Correlates with Tumor Progression and Poor Prognosis in Gastric Adenocarcinoma
by Ide, Munenori and Kato, Toshihide and Ogata, Kyoichi and Mochiki, Erito and Kuwano, Hiroyuki and Oyama, Tetsunari
Annals of surgical oncology, ISSN 1068-9265, 10/2012, Volume 19, Issue 11, pp. 3506 - 3514
Oncology | Medicine & Public Health | Surgical Oncology | Surgery | Life Sciences & Biomedicine | Science & Technology | Multivariate Analysis | Prognosis | Exoribonucleases | Homeodomain Proteins - metabolism | Humans | Middle Aged | Stomach Neoplasms - metabolism | Ki-67 Antigen - metabolism | Male | Stomach Neoplasms - pathology | Adenocarcinoma - metabolism | Biomarkers, Tumor - metabolism | Female | Exonucleases - metabolism | Kaplan-Meier Estimate | Proportional Hazards Models | Tumor Suppressor Protein p53 - metabolism | Lymphatic Metastasis | Neprilysin - metabolism | Adenocarcinoma - secondary | Disease Progression | 14-3-3 Proteins - metabolism | Keratin-17 - metabolism | Mucin 5AC - metabolism | Aged | CDX2 Transcription Factor | Neoplasm Staging | Mucin-6 - metabolism | Index Medicus
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