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Journal Article
Nature Structural and Molecular Biology, ISSN 1545-9993, 12/2013, Volume 20, Issue 12, pp. 1367 - 1376
Journal Article
Molecular Cell, ISSN 1097-2765, 11/2012, Volume 48, Issue 3, pp. 409 - 421
The exosome is a complex involved in the maturation of rRNA and sn-snoRNA, in the degradation of short-lived noncoding RNAs, and in the quality control of RNAs... 
II TRANSCRIPTS | RAPID TRANSFER-RNA | OXIDATIVE STRESS | MATURE TRANSFER-RNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | POLY(A) POLYMERASE | QUALITY-CONTROL | RIBOSOMAL-RNA | SACCHAROMYCES-CEREVISIAE | BIDIRECTIONAL PROMOTERS | NUCLEAR EXOSOME | CELL BIOLOGY | Introns - genetics | Oligonucleotide Array Sequence Analysis | RNA Processing, Post-Transcriptional | RNA, Transfer - metabolism | Saccharomyces cerevisiae - genetics | RNA, Ribosomal - metabolism | Substrate Specificity | RNA Precursors - genetics | Gene Expression Profiling | Saccharomyces cerevisiae Proteins - genetics | RNA, Ribosomal - genetics | RNA, Small Nucleolar - genetics | RNA, Fungal - metabolism | Saccharomyces cerevisiae - metabolism | Blotting, Northern | RNA, Small Nucleolar - metabolism | Saccharomyces cerevisiae Proteins - metabolism | RNA, Transfer - genetics | Exosome Multienzyme Ribonuclease Complex - metabolism | RNA Precursors - metabolism | RNA, Fungal - genetics | Mutation | Exosome Multienzyme Ribonuclease Complex - genetics | Analysis | Transfer RNA | Index Medicus | RNA Precursors | Introns | Quantitative Methods | Biochemistry, Molecular Biology | Genomics | Cellular Biology | RNA, Transfer | Bacteriology | Life Sciences | Microbiology and Parasitology | RNA, Ribosomal | RNA, Small Nucleolar | Saccharomyces cerevisiae Proteins | RNA, Fungal | Subcellular Processes | Exosome Multienzyme Ribonuclease Complex | Molecular biology | Saccharomyces cerevisiae
Journal Article
Journal Article
Nature, ISSN 0028-0836, 03/2011, Volume 471, Issue 7339, pp. 467 - 472
Multiple myeloma is an incurable malignancy of plasma cells, and its pathogenesis is poorly understood. Here we report the massively parallel sequencing of 38... 
PATHOGENESIS | B-CELL LYMPHOMA | BLIMP-1 | GENE | MULTIDISCIPLINARY SCIENCES | STRESS-RESPONSE | EXOSOME | CLASSIFICATION | DIFFERENTIATION | HUMAN CANCER | SOMATIC MUTATIONS | Ribonucleases - genetics | Ribonucleases - chemistry | Genomics | Humans | Molecular Sequence Data | NF-kappa B - metabolism | DNA Repair - genetics | Multiple Myeloma - drug therapy | DNA Mutational Analysis | Protein Biosynthesis - genetics | Multiple Myeloma - enzymology | Proto-Oncogene Proteins B-raf - metabolism | Amino Acid Sequence | Oncogenes - genetics | Models, Molecular | Exons - genetics | Signal Transduction - genetics | Multiple Myeloma - metabolism | Mutation - genetics | Open Reading Frames - genetics | Genome, Human - genetics | Homeodomain Proteins - genetics | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | RNA Processing, Post-Transcriptional - genetics | Proto-Oncogene Proteins B-raf - genetics | CpG Islands - genetics | Blood Coagulation - genetics | Protein Conformation | Histones - metabolism | Transcription, Genetic - genetics | Exosome Multienzyme Ribonuclease Complex | Methylation | Homeostasis - genetics | Multiple Myeloma - genetics | Usage | Multiple myeloma | Development and progression | Genetic aspects | Research | Nucleotide sequencing | Methods | Cancer | Proteins | Pathogenesis | Homeostasis | Genetics | Genomes | Mutation | Kinases | Mass spectrometry | Index Medicus
Journal Article
Molecular Cell, ISSN 1097-2765, 11/2016, Volume 64, Issue 4, pp. 734 - 745
The eukaryotic RNA exosome is an essential and conserved 3′-to-5′ exoribonuclease complex that degrades or processes nearly every class of cellular RNA. The... 
X-ray crystallography | RNA | RNA decay | click chemistry | exoribonuclease | nuclear | exosome | multi-subunit complex | structure | Saccharomyces cerevisiae - genetics | Allosteric Regulation | Substrate Specificity | Crystallography, X-Ray | Protein Subunits - metabolism | Saccharomyces cerevisiae - metabolism | Thermodynamics | Cell Nucleus - metabolism | Exosome Multienzyme Ribonuclease Complex - chemistry | Cloning, Molecular | Escherichia coli - metabolism | Exosome Multienzyme Ribonuclease Complex - metabolism | Protein Interaction Domains and Motifs | RNA, Fungal - genetics | Exosome Multienzyme Ribonuclease Complex - genetics | Binding Sites | Exosome Multienzyme Ribonuclease Complex - ultrastructure | Protein Subunits - genetics | Recombinant Proteins - metabolism | Protein Conformation, alpha-Helical | Gene Expression | RNA, Fungal - chemistry | Models, Molecular | Recombinant Proteins - chemistry | RNA Cleavage | Recombinant Proteins - genetics | Saccharomyces cerevisiae Proteins - genetics | Amino Acid Motifs | RNA, Fungal - metabolism | Cell Nucleus - genetics | Protein Conformation, beta-Strand | Escherichia coli - genetics | Saccharomyces cerevisiae Proteins - metabolism | Protein Binding | Protein Subunits - chemistry | Saccharomyces cerevisiae Proteins - chemistry | Phosphates | Structure | Crystals | Index Medicus
Journal Article
Journal Article
Journal Article