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Nature Structural and Molecular Biology, ISSN 1545-9993, 12/2013, Volume 20, Issue 12, pp. 1367 - 1376
Journal Article
Molecular Cell, ISSN 1097-2765, 11/2016, Volume 64, Issue 4, pp. 734 - 745
The eukaryotic RNA exosome is an essential and conserved 3′-to-5′ exoribonuclease complex that degrades or processes nearly every class of cellular RNA. The... 
X-ray crystallography | RNA | RNA decay | click chemistry | exoribonuclease | nuclear | exosome | multi-subunit complex | structure | Saccharomyces cerevisiae - genetics | Allosteric Regulation | Substrate Specificity | Crystallography, X-Ray | Protein Subunits - metabolism | Saccharomyces cerevisiae - metabolism | Thermodynamics | Cell Nucleus - metabolism | Exosome Multienzyme Ribonuclease Complex - chemistry | Cloning, Molecular | Escherichia coli - metabolism | Exosome Multienzyme Ribonuclease Complex - metabolism | Protein Interaction Domains and Motifs | RNA, Fungal - genetics | Exosome Multienzyme Ribonuclease Complex - genetics | Binding Sites | Exosome Multienzyme Ribonuclease Complex - ultrastructure | Protein Subunits - genetics | Recombinant Proteins - metabolism | Protein Conformation, alpha-Helical | Gene Expression | RNA, Fungal - chemistry | Models, Molecular | Recombinant Proteins - chemistry | RNA Cleavage | Recombinant Proteins - genetics | Saccharomyces cerevisiae Proteins - genetics | Amino Acid Motifs | RNA, Fungal - metabolism | Cell Nucleus - genetics | Protein Conformation, beta-Strand | Escherichia coli - genetics | Saccharomyces cerevisiae Proteins - metabolism | Protein Binding | Protein Subunits - chemistry | Saccharomyces cerevisiae Proteins - chemistry | Phosphates | Structure | Crystals | Index Medicus
Journal Article
Journal Article
Journal Article
Molecular Cell, ISSN 1097-2765, 07/2016, Volume 63, Issue 1, pp. 125 - 134
The RNA exosome complex associates with nuclear and cytoplasmic cofactors to mediate the decay, surveillance, or processing of a wide variety of transcripts.... 
MESSENGER-RNA | CRYSTAL-STRUCTURE | CENTRAL CHANNEL | BIOCHEMISTRY & MOLECULAR BIOLOGY | QUALITY-CONTROL SYSTEMS | SKI COMPLEX | TRANSLATION ELONGATION | MACROMOLECULAR ASSEMBLIES | EUKARYOTIC EXOSOME | SACCHAROMYCES-CEREVISIAE | NUCLEAR EXOSOME | CELL BIOLOGY | Adaptor Proteins, Signal Transducing - chemistry | Peptide Elongation Factors - metabolism | Saccharomyces cerevisiae - genetics | Humans | Structure-Activity Relationship | GTP-Binding Proteins - genetics | Saccharomyces cerevisiae - metabolism | Exosome Multienzyme Ribonuclease Complex - chemistry | Conserved Sequence | Exosome Multienzyme Ribonuclease Complex - metabolism | Protein Interaction Domains and Motifs | Exosome Multienzyme Ribonuclease Complex - genetics | Binding Sites | Peptide Elongation Factors - genetics | Amino Acid Sequence | Models, Molecular | HSP70 Heat-Shock Proteins - genetics | Nuclear Proteins - metabolism | Saccharomyces cerevisiae Proteins - genetics | HSP70 Heat-Shock Proteins - metabolism | Protein Isoforms | Adaptor Proteins, Signal Transducing - genetics | Saccharomyces cerevisiae Proteins - metabolism | Hydrophobic and Hydrophilic Interactions | Protein Binding | Protein Conformation | Mutation | Adaptor Proteins, Signal Transducing - metabolism | Evolution, Molecular | GTP-Binding Proteins - metabolism | Saccharomyces cerevisiae Proteins - chemistry | Sports facilities | RNA | Cells | Protein binding | Index Medicus
Journal Article
Cell, ISSN 0092-8674, 06/2018, Volume 173, Issue 7, pp. 1663 - 1677.e21
Journal Article
细胞研究:英文版, ISSN 1001-0602, 2016, Volume 26, Issue 7, pp. 822 - 837
Journal Article