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1. Full Text Efficient tumour formation by single human melanoma cells
by Quintana, Elsa and Shackleton, Mark and Sabel, Michael S and Fullen, Douglas R and Johnson, Timothy M and Morrison, Sean J
Nature (London), ISSN 0028-0836, 12/2008, Volume 456, Issue 7222, pp. 593 - 598
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Biological and medical sciences | Medical sciences | Animal tumors. Experimental tumors | Experimental tumors, general aspects | Tumors | Interleukin Receptor Common gamma Subunit - deficiency | Neoplasm Transplantation | Animals | Cell Count | Humans | Neoplastic Stem Cells - pathology | Mice, Inbred NOD | Transplantation, Heterologous | Mice | Melanoma - pathology | Mice, SCID | Interleukin Receptor Common gamma Subunit - genetics | Cancer cells | Melanoma | Physiological aspects | Development and progression | Genetic aspects | Research | Properties | Risk factors | Medical research | Stem cells | Cancer | Index Medicus
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2. Full Text Expression of Follicle-Stimulating Hormone Receptor in Tumor Blood Vessels
by Radu, Aurelian and Pichon, Christophe and Camparo, Philippe and Antoine, Martine and Allory, Yves and Couvelard, Anne and Fromont, Gaëlle and Hai, Mai Thu Vu and Ghinea, Nicolae
The New England journal of medicine, ISSN 0028-4793, 10/2010, Volume 363, Issue 17, pp. 1621 - 1630
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Biological and medical sciences | General aspects | Medical sciences | Endothelial Cells - chemistry | Prostatic Neoplasms - blood supply | Neoplasm Transplantation | Prostatic Neoplasms - chemistry | Blood Vessels - chemistry | Immunologic Techniques | Receptors, FSH - immunology | Electrophoresis, Polyacrylamide Gel | Humans | Male | Neoplasms - blood supply | Transplantation, Heterologous | Microscopy, Immunoelectron | Neoplasms - chemistry | Animals | In Situ Hybridization | Antibodies, Monoclonal - analysis | Neoplasms, Experimental - chemistry | Mice | Disease Models, Animal | Neoplasms, Experimental - blood supply | Receptors, FSH - analysis | Care and treatment | Follicle-stimulating hormone | Blood-vessels | Analysis | Physiological aspects | Genetic aspects | Gene expression | Health aspects | Cancer | Tumors | Proteins | Microscopy | Rodents | Surgery | Index Medicus | Abridged Index Medicus
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3. Full Text Dual blockade of PD-1 and CTLA-4 combined with tumor vaccine effectively restores T-cell rejection function in tumors
by Duraiswamy, Jaikumar and Kaluza, Karen M and Freeman, Gordon J and Coukos, George
Cancer research (Chicago, Ill.), ISSN 0008-5472, 06/2013, Volume 73, Issue 12, pp. 3591 - 3603
Life Sciences & Biomedicine | Oncology | Science & Technology | Biological and medical sciences | Multiple tumors. Solid tumors. Tumors in childhood (general aspects) | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Tumors | T-Lymphocytes, Regulatory - metabolism | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Antibodies, Blocking - pharmacology | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | Neoplasms, Experimental - pathology | Flow Cytometry | T-Lymphocytes - metabolism | Neoplasms, Experimental - immunology | CD8-Positive T-Lymphocytes - metabolism | Female | Lymphocytes, Tumor-Infiltrating - metabolism | Cytokines - immunology | Cytokines - metabolism | Cancer Vaccines - administration & dosage | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Neoplasms, Experimental - therapy | CTLA-4 Antigen - metabolism | Lymphocytes, Tumor-Infiltrating - transplantation | Programmed Cell Death 1 Receptor - metabolism | Combined Modality Therapy | CTLA-4 Antigen - immunology | B7-H1 Antigen - immunology | Cancer Vaccines - immunology | B7-H1 Antigen - metabolism | Animals | Antibodies, Blocking - immunology | T-Lymphocytes - immunology | Mice | Mice, Inbred BALB C | Programmed Cell Death 1 Receptor - immunology | CD8-Positive T-Lymphocytes - immunology | CTLA-4 Antigen - antagonists & inhibitors | Lymphocytes, Tumor-Infiltrating - immunology | Tumor Burden - immunology | Index Medicus
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4. Full Text Bilateral Tumors — Inherited or Acquired?
by Foulkes, William D and Polak, Paz
The New England journal of medicine, ISSN 0028-4793, 07/2020, Volume 383, Issue 3, pp. 280 - 282
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Zygotes | Medical research | Care and treatment | Genetic susceptibility | Medicine, Experimental | Genetic aspects | Research | Nephroblastoma | Health aspects | Sentinel health events | Risk factors | Kidneys | Families & family life | Tumorigenesis | Genomes | Genetic testing | Family medical history | Mutation | Deoxyribonucleic acid--DNA | Tumors | Index Medicus | Abridged Index Medicus
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5. Full Text Colorectal cancer
by Brenner, Hermann, Prof and Kloor, Matthias, MD and Pox, Christian Peter, MD
The Lancet (British edition), ISSN 0140-6736, 2014, Volume 383, Issue 9927, pp. 1490 - 1502
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Gastroenterology. Liver. Pancreas. Abdomen | Stomach. Duodenum. Small intestine. Colon. Rectum. Anus | General aspects | Biological and medical sciences | Multiple tumors. Solid tumors. Tumors in childhood (general aspects) | Medical sciences | Tumors | Colorectal Neoplasms - epidemiology | Primary Prevention | Prognosis | Age Factors | Global Health | Humans | Risk Factors | Colorectal Neoplasms - prevention & control | Patient Care Team | Male | Survival Rate | Secondary Prevention | Incidence | Diagnostic Imaging | Colorectal Neoplasms - therapy | Sex Factors | Female | Colorectal Neoplasms - pathology | Neoplasm Staging | Tertiary Prevention | Care and treatment | Diagnosis | Patient outcomes | Methods | Colorectal cancer | Cancer | Oncology, Experimental | Mortality | Adjuvant treatment | Research | Health aspects | Epidemiology | Germany | Chemotherapy | Pathogenesis | Medical prognosis | Cancer therapies | Age | Index Medicus | Abridged Index Medicus
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6. Full Text RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth
by Hatzivassiliou, Georgia and Song, Kyung and Yen, Ivana and Brandhuber, Barbara J and Anderson, Daniel J and Alvarado, Ryan and Ludlam, Mary J. C and Stokoe, David and Gloor, Susan L and Vigers, Guy and Morales, Tony and Aliagas, Ignacio and Liu, Bonnie and Sideris, Steve and Hoeflich, Klaus P and Jaiswal, Bijay S and Seshagiri, Somasekar and Koeppen, Hartmut and Belvin, Marcia and Friedman, Lori S and Malek, Shiva
Nature (London), ISSN 0028-0836, 03/2010, Volume 464, Issue 7287, pp. 431 - 435
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | General aspects | Pharmacology. Drug treatments | Biological and medical sciences | Medical sciences | Animal tumors. Experimental tumors | Experimental tumors, general aspects | Antineoplastic agents | Tumors | Neoplasms - metabolism | ras Proteins - genetics | Proto-Oncogene Proteins p21(ras) | Diphenylamine - pharmacology | raf Kinases - antagonists & inhibitors | Humans | Protein Multimerization | ras Proteins - metabolism | Protein Transport - drug effects | Extracellular Signal-Regulated MAP Kinases - metabolism | raf Kinases - metabolism | Diphenylamine - analogs & derivatives | Mitogen-Activated Protein Kinase Kinases - metabolism | Adenosine Triphosphate - metabolism | Indoles - pharmacology | Benzamides - pharmacology | Cell Membrane - metabolism | raf Kinases - genetics | Cell Membrane - drug effects | Proto-Oncogene Proteins B-raf - metabolism | Proto-Oncogene Proteins B-raf - chemistry | Pyrazoles - pharmacology | Protein Structure, Tertiary | Proto-Oncogene Proteins - metabolism | Cell Line | Indenes - pharmacology | raf Kinases - chemistry | Proto-Oncogene Proteins c-raf - genetics | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | Neoplasms - enzymology | Proto-Oncogene Proteins - genetics | Enzyme Activation - drug effects | Sulfonamides - pharmacology | Proto-Oncogene Proteins c-raf - metabolism | Neoplasms - drug therapy | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Xenograft Model Antitumor Assays | Animals | MAP Kinase Signaling System - drug effects | Protein Kinase Inhibitors - therapeutic use | Proto-Oncogene Proteins B-raf - genetics | Proto-Oncogene Proteins c-raf - deficiency | Cell Proliferation - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Neoplasms - pathology | Ras genes | Growth | Physiological aspects | Cellular signal transduction | Genetic aspects | Research | Mitogen-activated protein kinases | Competition | Clinical trials | Enzymes | Kinases | Index Medicus | Proteins | Cellular | Inhibitors | Pathways | Tumours | Signalling | Dimerization
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7. Full Text Tumor vasculature‐targeted delivery of tumor necrosis factor‐α
by Tandle, Anita and Hanna, Engy and Lorang, Dominique and Hajitou, Amin and Moya, Catherine A and Pasqualini, Renata and Arap, Wadih and Adem, Asha and Starker, Elizabeth and Hewitt, Stephen and Libutti, Steven K
Cancer, ISSN 0008-543X, 01/2009, Volume 115, Issue 1, pp. 128 - 139
targeted gene therapy | tumor necrosis factor α | human melanoma | adeno‐associated virus phage vector | antivascular | Human melanoma | Antivascular | Targeted gene therapy | Adeno-associated virus phage vector | Tumor necrosis factor α | Life Sciences & Biomedicine | Oncology | Science & Technology | Biological and medical sciences | Treatment. General aspects | Other treatments | Medical sciences | Animal tumors. Experimental tumors | Experimental tumors, general aspects | Tumors | Tumor Necrosis Factor-alpha - metabolism | Dependovirus - genetics | Neoplasm Transplantation | Gene Expression | Transduction, Genetic | Melanoma - blood supply | Melanoma, Experimental - blood supply | Skin Neoplasms - therapy | Humans | Melanoma, Experimental - therapy | Tumor Necrosis Factor-alpha - genetics | Animals | Mice, Nude | Cell Line, Tumor | Mice | Skin Neoplasms - blood supply | Genetic Vectors | Melanoma - therapy | Genetic Therapy - methods | Index Medicus | Abridged Index Medicus
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8. Full Text Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis
by Sawamiphak, Suphansa and Seidel, Sascha and Essmann, Clara L and Wilkinson, George A and Pitulescu, Mara E and Acker, Till and Acker-Palmer, Amparo
Nature (London), ISSN 0028-0836, 05/2010, Volume 465, Issue 7297, pp. 487 - 491
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Biological and medical sciences | Medical sciences | Animal tumors. Experimental tumors | Experimental tumors, general aspects | Tumors | Astrocytoma - metabolism | Astrocytoma - blood supply | Neoplasm Transplantation | Ephrin-B2 - deficiency | Signal Transduction | Endothelial Cells - metabolism | Mice, Inbred C57BL | Cells, Cultured | Neovascularization, Pathologic | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Retina | Ephrin-B2 - metabolism | Retinal Vessels - physiology | Ephrin-B2 - genetics | Brain - blood supply | Astrocytoma - pathology | Endocytosis | Animals | Pseudopodia - metabolism | Endothelial Cells - cytology | Retinal Vessels - cytology | Mice | Neovascularization, Physiologic | Control | Ephrins | Physiological aspects | Genetic aspects | Research | Neovascularization | Vascular endothelial growth factor | Risk factors | Proteins | Studies | Angiogenesis | Rodents | Membrane filters | Index Medicus
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