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Nature (London), ISSN 1476-4687, 2011, Volume 472, Issue 7344, pp. 466 - 470
... by interventions that are associated with beneficial effects on cognition and mood, such as learning... 
DEPRESSION | MODELS | MEMORY | MULTIDISCIPLINARY SCIENCES | NEURONS | DISORDER | DENTATE GYRUS | MATURATION | SYNAPTIC PLASTICITY | FLUOXETINE | BRAIN | Apoptosis - drug effects | Learning - drug effects | Neuronal Plasticity - drug effects | Male | Neural Stem Cells - cytology | Anxiety - therapy | Neuronal Plasticity - physiology | Long-Term Potentiation - drug effects | Exploratory Behavior - drug effects | Cognition - physiology | Long-Term Potentiation - physiology | Antidepressive Agents - pharmacology | bcl-2-Associated X Protein - deficiency | Extinction, Psychological - physiology | Cell Survival - drug effects | Synapses - drug effects | Conditioning, Classical - drug effects | Affect - physiology | bcl-2-Associated X Protein - metabolism | Anxiety - physiopathology | Mice, Transgenic | Hippocampus - pathology | Cognition - drug effects | Mice, Knockout | Dentate Gyrus - cytology | Aging - physiology | Dentate Gyrus - physiology | Mice | Dentate Gyrus - pathology | Hippocampus - physiopathology | Memory - physiology | Memory - drug effects | Aging - drug effects | Extinction, Psychological - drug effects | Fear - physiology | Dentate Gyrus - physiopathology | Exploratory Behavior - physiology | Synapses - metabolism | Fear - psychology | Female | Neurogenesis - drug effects | bcl-2-Associated X Protein - genetics | Neural Stem Cells - drug effects | Hippocampus - cytology | Physical Conditioning, Animal - physiology | Conditioning, Classical - physiology | Aging - pathology | Learning - physiology | Animals | Neurogenesis - physiology | Models, Neurological | Hippocampus - physiology | Neural Stem Cells - metabolism | Physiological aspects | Hippocampus (Brain) | Neurogenesis | Health aspects | Proteins | Studies | Young adults | Cognition & reasoning | Neurons | Anxieties | Rodents | Behavior
Journal Article
Biological Psychiatry, ISSN 0006-3223, 2012, Volume 72, Issue 7, pp. 528 - 536
... worldwide each year ( 2 ). In addition to depressive behavior, impulsiveness, hostility, and aggressiveness are traits associated with suicidal behavior, considered... 
Psychiatry | Antidepressant | CREB | fluoxetine | BDNF | mood disorders | neuroplasticity genes regulation | transcriptional coactivator | major depression | PSYCHIATRY | NEUROTROPHIC FACTOR | ELEMENT-BINDING PROTEIN | ANGER ATTACKS | BIPOLAR DISORDER | ANTIDEPRESSANT DRUGS | CAMP RESPONSE | NEUROSCIENCES | BDNF TRANSCRIPTION | SUICIDE ATTEMPTS | ANIMAL-MODELS | Fear - drug effects | Neuronal Plasticity - drug effects | Male | Receptor, trkB - genetics | Orphan Nuclear Receptors - metabolism | Arabidopsis Proteins - metabolism | Brain - metabolism | Nesting Behavior - drug effects | Sexual Behavior, Animal - physiology | Swimming - psychology | Exploratory Behavior - drug effects | Brain-Derived Neurotrophic Factor - metabolism | Sexual Behavior, Animal - drug effects | Disease Models, Animal | Fluoxetine - pharmacology | Maze Learning - physiology | Food Preferences - drug effects | Antidepressive Agents, Second-Generation - pharmacology | Signal Transduction - genetics | Hindlimb Suspension | Depressive Disorder - metabolism | Maternal Behavior - drug effects | Orphan Nuclear Receptors - genetics | Mice, Knockout | Signal Transduction - drug effects | Brain - pathology | Mice | Biogenic Monoamines - metabolism | Aggression - physiology | Brain-Derived Neurotrophic Factor - genetics | Electroshock - adverse effects | Food Preferences - physiology | Transcription Factors - deficiency | Depressive Disorder - drug therapy | Chromatography, High Pressure Liquid | Antidepressive Agents, Second-Generation - therapeutic use | Exploratory Behavior - physiology | Neuronal Plasticity - genetics | Social Behavior | Fear - psychology | Female | Corticosterone - blood | Fluoxetine - therapeutic use | Depressive Disorder - genetics | Enzyme-Linked Immunosorbent Assay | Gene Expression Regulation - genetics | Mice, Inbred C57BL | Nesting Behavior - physiology | Maternal Behavior - physiology | Maze Learning - drug effects | Intramolecular Transferases - metabolism | Transcription Factors - metabolism | Animals | Aggression - drug effects | Receptor, trkB - metabolism | Neurosciences | Fluoxetine | Analysis | Genes | Depression, Mental | Disease susceptibility | Genetic transcription | Adenylic acid | Protein binding
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 05/2010, Volume 30, Issue 21, pp. 7152 - 7167
... (Set domain, bifurcated 1)/Eset/Kmt1e are associated with repressive chromatin remodeling and expressed in adult brain, but potential effects on neuronal function and behavior remain unexplored... 
DEPRESSION | CHROMATIN REGULATION | DEACETYLASE INHIBITOR | DNA METHYLATION | GENE | SODIUM-BUTYRATE | MOUSE MODEL | HIPPOCAMPAL | METABOTROPIC GLUTAMATE RECEPTORS | NEUROSCIENCES | METHYL-D-ASPARTATE | Chromatin - metabolism | Immobility Response, Tonic - physiology | Humans | Receptors, N-Methyl-D-Aspartate - metabolism | Fear - drug effects | Green Fluorescent Proteins - genetics | Protein Methyltransferases - metabolism | Neurons - ultrastructure | Excitatory Amino Acid Agents - pharmacology | Exploratory Behavior - drug effects | Behavior, Animal - drug effects | Excitatory Postsynaptic Potentials - genetics | Animals, Newborn | Membrane Potentials - drug effects | Adaptation, Ocular - genetics | Maze Learning - physiology | Food Preferences - drug effects | Histone-Lysine N-Methyltransferase | Affect - physiology | Behavior, Animal - physiology | Mice, Transgenic | Avoidance Learning - physiology | Avoidance Learning - drug effects | Mice | Membrane Potentials - genetics | Electroshock - adverse effects | Age Factors | Food Preferences - physiology | Protein Methyltransferases - genetics | Adaptation, Ocular - drug effects | Motor Activity - drug effects | Fear - physiology | Excitatory Postsynaptic Potentials - drug effects | Patch-Clamp Techniques - methods | Receptors, N-Methyl-D-Aspartate - genetics | Exploratory Behavior - physiology | Transfection - methods | Neurons - physiology | Chromatin Immunoprecipitation - methods | Immobility Response, Tonic - drug effects | Neurons - drug effects | Sucrose - administration & dosage | Affect - drug effects | Conditioning (Psychology) - drug effects | Conditioning (Psychology) - physiology | Gene Expression Regulation - genetics | Mice, Inbred C57BL | RNA, Small Interfering - pharmacology | Cells, Cultured | Gene Expression Regulation - physiology | Hippocampus - cytology | Maze Learning - drug effects | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - genetics | Gene Expression Regulation - drug effects | Motor Activity - genetics | Animals | Sweetening Agents - administration & dosage
Journal Article
Neuropharmacology, ISSN 0028-3908, 09/2013, Volume 72, pp. 187 - 196
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 12/2009, Volume 29, Issue 48, pp. 15245 - 15257
.... Infusion of the antimitotic drug AraC to the lateral ventricle via 28 d osmotic minipumps abolished the arrival of newly born neurons into the adult OB without affecting the total number of granule cells... 
FOREBRAIN | INHIBITION | INTEGRATION | DISCRIMINATION | BORN | INCREASES | STIMULATED NEUROGENESIS | GAMMA-OSCILLATIONS | GRANULE CELLS | NEUROSCIENCES | NEWBORN NEURONS | Interneurons - physiology | Cytarabine - pharmacology | gamma-Aminobutyric Acid - metabolism | Male | Phosphopyruvate Hydratase - metabolism | Green Fluorescent Proteins - genetics | Nerve Net - drug effects | Nerve Net - physiology | Odorants | Smell - physiology | Time Factors | Exploratory Behavior - drug effects | Olfactory Perception - physiology | Discrimination (Psychology) - drug effects | Lysine - metabolism | Neurogenesis - drug effects | Bromodeoxyuridine - metabolism | Electric Stimulation - methods | Immunosuppressive Agents - pharmacology | Potassium Channel Blockers - pharmacology | Locomotion - drug effects | Olfactory Bulb - cytology | Lysine - analogs & derivatives | Mice, Inbred C57BL | Interneurons - drug effects | Biophysics | Hindlimb Suspension - methods | Association Learning - physiology | Association Learning - drug effects | Evoked Potentials - drug effects | Patch-Clamp Techniques | Ablation Techniques - methods | Animals | Recognition (Psychology) - drug effects | Sensory Thresholds - physiology | Discrimination (Psychology) - physiology | Mice | Locomotion - physiology | Inhibitory Postsynaptic Potentials - drug effects | Sensory Thresholds - drug effects
Journal Article
Molecular Psychiatry, ISSN 1359-4184, 05/2016, Volume 21, Issue 5, pp. 615 - 623
Memories associated with drug use increase vulnerability to relapse in substance use disorder (SUD... 
COCAINE-SEEKING BEHAVIOR | STRUCTURAL PLASTICITY | PSYCHIATRY | BASOLATERAL AMYGDALA | BIOCHEMISTRY & MOLECULAR BIOLOGY | ACTIN-FILAMENT | D-CYCLOSERINE | DISTINCT ROLES | NEUROSCIENCES | DENDRITIC SPINES | MEMORY | LATERAL AMYGDALA | RAT FOREBRAIN | Memory - drug effects | Motor Activity - physiology | Amygdala - drug effects | Nonmuscle Myosin Type IIB - metabolism | Fear - drug effects | Motor Activity - drug effects | Male | Amphetamine-Related Disorders - pathology | Secondary Prevention | Fear - physiology | Heterocyclic Compounds, 4 or More Rings - pharmacology | Gene Knockdown Techniques | Exploratory Behavior - physiology | Nonmuscle Myosin Type IIB - antagonists & inhibitors | Self Administration | Exploratory Behavior - drug effects | Spatial Behavior - drug effects | Amphetamine-Related Disorders - metabolism | Disease Models, Animal | Conditioning (Psychology) - drug effects | Conditioning (Psychology) - physiology | Nonmuscle Myosin Type IIB - genetics | Drug-Seeking Behavior - physiology | Amygdala - metabolism | Rats | Spatial Behavior - physiology | Amphetamine-Related Disorders - drug therapy | Drug-Seeking Behavior - drug effects | Animals | Methamphetamine - administration & dosage | Central Nervous System Agents - administration & dosage | Mice | Memory - physiology | Care and treatment | Myosin | Innovations | Methamphetamine | Drug targeting | Substance abuse | Properties | Health aspects | drug seeking | memory | synapse | Actin | retrieval | addiction
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 02/2013, Volume 33, Issue 9, pp. 3953 - 3966
Down syndrome (DS) is associated with neurological complications, including cognitive deficits that lead to impairment in intellectual functioning. Increased... 
Protein Binding - genetics | Electric Stimulation | Cell Count | Male | GABA Modulators - therapeutic use | Learning Disorders - etiology | Hyperkinesis - drug therapy | Neurogenesis - genetics | Long-Term Potentiation - drug effects | Protein Binding - drug effects | Exploratory Behavior - drug effects | Reflex, Startle - drug effects | Imidazoles - therapeutic use | Excitatory Postsynaptic Potentials - genetics | Disease Models, Animal | Mice, Transgenic | Hippocampus - pathology | Imidazoles - pharmacology | Psychomotor Performance - drug effects | Hyperkinesis - etiology | Vesicular Inhibitory Amino Acid Transport Proteins - metabolism | Analysis of Variance | Seizures - etiology | Glutamate Decarboxylase - metabolism | Mice | Receptors, GABA-A - metabolism | Benzodiazepines - therapeutic use | Tritium - pharmacokinetics | Sensory Gating - drug effects | Reflex - genetics | Reflex - drug effects | Hippocampus - drug effects | Excitatory Postsynaptic Potentials - drug effects | Ki-67 Antigen | Reaction Time - drug effects | GABA Modulators - pharmacology | Neurons - physiology | Down Syndrome - complications | Membrane Proteins - metabolism | Neurogenesis - drug effects | Neurons - drug effects | Cues | Down Syndrome - pathology | Benzodiazepines - pharmacology | Acoustic Stimulation | Mice, Inbred C57BL | Learning Disorders - drug therapy | Long-Term Potentiation - genetics | Biophysics | Maze Learning - drug effects | Rotarod Performance Test | Animals | Carrier Proteins - metabolism | Down Syndrome - drug therapy | Cell Proliferation - drug effects
Journal Article
Journal of neuroinflammation, ISSN 1742-2094, 2008, Volume 5, Issue 1, pp. 15 - 15
...)-induced neuroinflammation, sickness behavior, and anhedonia. Methods: In the first set of experiments the effect of minocycline pretreatment on LPS-induced microglia activation was assessed in BV-2 microglia cell cultures... 
OXIDATIVE STRESS | QUINOLINIC ACID | MICROGLIAL ACTIVATION | PERIPHERAL INFECTION | INDOLEAMINE 2,3-DIOXYGENASE | ALPHA-TOCOPHEROL | ANIMAL-MODEL | AGED MICE | IMMUNOLOGY | BLOOD-BRAIN-BARRIER | NEUROSCIENCES | TRANSGENIC MICE | Mood Disorders - drug therapy | Age Factors | Minocycline - pharmacology | Cerebral Cortex - pathology | Male | Endotoxemia - pathology | Endotoxemia - psychology | Hippocampus - drug effects | Interleukin-1beta - genetics | Sick Role | Cerebral Cortex - metabolism | Interleukin-1beta - blood | Mood Disorders - etiology | RNA, Messenger - biosynthesis | Interleukin-6 - blood | Minocycline - therapeutic use | Endotoxemia - immunology | Exploratory Behavior - drug effects | Cerebral Cortex - drug effects | Dietary Sucrose | Drug Evaluation, Preclinical | Cell Line | Microglia - secretion | Specific Pathogen-Free Organisms | Interleukin-6 - genetics | Microglia - drug effects | Food Preferences - drug effects | Endotoxemia - drug therapy | RNA, Messenger - genetics | Hippocampus - pathology | Toll-Like Receptor 2 - biosynthesis | Hippocampus - metabolism | Animals | Endotoxemia - complications | Social Behavior Disorders - etiology | Social Behavior Disorders - prevention & control | Mice | Mice, Inbred BALB C | Endotoxins - toxicity | Nervous system diseases | Care and treatment | Polysaccharides | Physiological aspects | Minocycline | Dosage and administration | Research | Health aspects | Index Medicus
Journal Article
Journal of Psychiatric Research, ISSN 0022-3956, 2013, Volume 47, Issue 10, pp. 1521 - 1529
Journal Article
Journal Article
Neuropsychopharmacology (New York, N.Y.), ISSN 1740-634X, 2013, Volume 39, Issue 5, pp. 1102 - 1114