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Nature genetics, ISSN 1546-1718, 01/2014, Volume 46, Issue 3, pp. 279 - 286
The molecular mechanisms determining the transmissibility and prevalence of drug-resistant tuberculosis in a population were investigated through whole-genome sequencing of 1,000 prospectively... 
Genes, Bacterial | Prevalence | Prospective Studies | Humans | Drug Resistance, Multiple, Bacterial/genetics | Mycobacterium tuberculosis/drug effects | Phylogeny | Tuberculosis, Multidrug-Resistant/epidemiology | Virulence/genetics | Bacterial Proteins/genetics | DNA-Directed RNA Polymerases | Russia/epidemiology | Polymorphism, Single Nucleotide | Mutation | Evolution, Molecular | Extensively Drug-Resistant Tuberculosis/epidemiology | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Bacterial Proteins - genetics | Mycobacterium tuberculosis - drug effects | Tuberculosis, Multidrug-Resistant - epidemiology | Extensively Drug-Resistant Tuberculosis - epidemiology | Mycobacterium tuberculosis - pathogenicity | Tuberculosis, Multidrug-Resistant - microbiology | Virulence - genetics | Extensively Drug-Resistant Tuberculosis - transmission | Tuberculosis, Multidrug-Resistant - transmission | Extensively Drug-Resistant Tuberculosis - microbiology | Drug Resistance, Multiple, Bacterial - genetics | Russia - epidemiology | Mycobacterium tuberculosis - genetics | Drug resistance in microorganisms | Medical research | Disease transmission | Tuberculosis | Medicine, Experimental | Genetic aspects | Research | Confidence intervals | Antibiotics | Mortality | Software | Genomes | Drug resistance | Patients | Public health | Index Medicus
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