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Circulation research, ISSN 0009-7330, 10/2012, Volume 111, Issue 9, pp. 1125 - 1136
Journal Article
PLoS pathogens, ISSN 1553-7374, 05/2015, Volume 11, Issue 5, pp. e1004917 - e1004917
.... The mechanism of matrix destruction resulting in cavitation is not well defined. Neutrophils are emerging as key mediators of TB immunopathology and their influx are associated with poor outcomes... 
Parasitology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Virology | AMP-Activated Protein Kinases - metabolism | Tuberculosis, Pulmonary - metabolism | Respiratory Mucosa - drug effects | Humans | Mycobacterium tuberculosis - immunology | NF-kappa B - metabolism | Tuberculosis, Pulmonary - drug therapy | Host-Pathogen Interactions - drug effects | Mycobacterium tuberculosis - drug effects | Respiratory Mucosa - pathology | Proteolysis - drug effects | Protein Processing, Post-Translational - drug effects | Matrix Metalloproteinase 8 - metabolism | Respiratory Mucosa - immunology | Mycobacterium tuberculosis - physiology | Adult | Lung - metabolism | Phosphorylation - drug effects | Neutrophils - metabolism | Extracellular Matrix Proteins - metabolism | Neutrophil Infiltration - drug effects | Neutrophils - pathology | Lung - pathology | Immunity, Innate - drug effects | Neutrophils - enzymology | Cells, Cultured | Enzyme Inhibitors - pharmacology | Neutrophils - immunology | Tuberculosis, Pulmonary - pathology | Matrix Metalloproteinase 8 - chemistry | Tuberculosis, Pulmonary - immunology | Active Transport, Cell Nucleus - drug effects | Lung - drug effects | Respiratory Mucosa - metabolism | Sputum - enzymology | Lung - immunology | Cohort Studies | Index Medicus | Proteins | Studies | Pathology | Tuberculosis | Biomedical research | Disease | Biopsy | Infections | Kinases | Metabolism | Experiments
Journal Article
The American journal of pathology, ISSN 0002-9440, 04/2017, Volume 187, Issue 4, pp. 781 - 797
Journal Article
Journal Article
PLoS biology, ISSN 1545-7885, 10/2018, Volume 16, Issue 10, pp. e2006872 - e2006872
... matrix and because biofilm cells exhibit... 
Biochemistry & Molecular Biology | Biology | Life Sciences & Biomedicine - Other Topics | Life Sciences & Biomedicine | Science & Technology | Biofilms - drug effects | Candida albicans - pathogenicity | Microscopy, Electron, Scanning | Extracellular Vesicles - ultrastructure | Humans | Biofilms - growth & development | Extracellular Polymeric Substance Matrix - physiology | Endosomal Sorting Complexes Required for Transport - genetics | Lipid Metabolism | Cryoelectron Microscopy | Microbial Interactions - drug effects | Extracellular Vesicles - drug effects | Microbial Interactions - physiology | Candida albicans - drug effects | Models, Biological | Extracellular Vesicles - physiology | Candida albicans - physiology | Extracellular Polymeric Substance Matrix - drug effects | Mutation | Drug Resistance, Fungal | Endosomal Sorting Complexes Required for Transport - physiology | Extracellular Polymeric Substance Matrix - ultrastructure | Proteome - metabolism | Fungal Proteins - metabolism | Flow cytometry | Chemical communication | Relaying | Medical equipment | Fourier transforms | Fungicides | Communities | Lipids | Biosynthesis | Drug resistance | Cell interactions | Lipid bilayers | Proteins | Polysaccharides | Vesicles | Eukaryotes | Microorganisms | Immunology | Extracellular matrix | Evolution | Quorum sensing | Planktonic cells | Fluconazole | Hypersensitivity | Antimicrobial agents | Gene expression | Mutants | Medicine | Biofilms | Infectious diseases | Scientific imaging | Diabetes | Mass spectrometry | Index Medicus | life sciences & biomedicine | BASIC BIOLOGICAL SCIENCES | biochemistry & molecular biology
Journal Article
Biomaterials, ISSN 0142-9612, 05/2015, Volume 50, Issue 1, pp. 75 - 86
Abstract Successful bone tissue engineering generally requires an osteoconductive scaffold that consists of extracellular matrix (ECM... 
Advanced Basic Science | Dentistry | Extracellular matrix (ECM) | Bone morphogenic protein (BMP)-2 | Bone tissue engineering | Cell-derived matrix | Microenvironment | Polymer mesh scaffold | Engineering | Materials Science | Technology | Engineering, Biomedical | Materials Science, Biomaterials | Science & Technology | Bone Morphogenetic Protein 2 - pharmacology | Bone and Bones - pathology | Calcium - metabolism | Humans | Extracellular Matrix - metabolism | Fibroblasts - ultrastructure | Bone and Bones - drug effects | Tissue Scaffolds - chemistry | Mesenchymal Stromal Cells - cytology | Placenta - cytology | Skull - pathology | Female | Skull - drug effects | Wound Healing - drug effects | Disease Models, Animal | Osseointegration - drug effects | Bone Regeneration - drug effects | Mesenchymal Stromal Cells - drug effects | Extracellular Matrix - drug effects | Osteogenesis - drug effects | Biocompatible Materials - pharmacology | Rats, Sprague-Dawley | Pregnancy | Extracellular Matrix - ultrastructure | Animals | Cell Differentiation - drug effects | Mice, Nude | Fibroblasts - drug effects | Immobilized Proteins - pharmacology | Polymers - pharmacology | Polymers - chemistry | Fibroblasts - cytology | Fibronectins | Biological products | Glycosaminoglycans | Tissue engineering | Analysis | Stem cells | Anticoagulants (Medicine) | Polymer industry | Polymers | Index Medicus | Finite element method | Biomedical materials | Biocompatibility | Bones | Coating | Scaffolds | Heparins | Defects
Journal Article
Molecular pharmaceutics, ISSN 1543-8384, 07/2014, Volume 11, Issue 7, pp. 2115 - 2125
... in a physiologically relevant and controllable manner. Here we report the development of a bioengineered 3D brain tumor model to help elucidate the effects of matrix stiffness on GBM cell fate using poly(ethylene-glycol) (PEG... 
hydrogels | glioblastoma | three-dimensional | tumor microenvironment | tumor model | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Biomimetics - methods | Gene Expression - drug effects | Gene Expression - genetics | Proto-Oncogene Proteins p21(ras) - genetics | Humans | Brain Neoplasms - pathology | Spheroids, Cellular - pathology | Extracellular Matrix - metabolism | Hyaluronic Acid - pharmacology | rhoA GTP-Binding Protein - metabolism | rhoA GTP-Binding Protein - genetics | Brain Neoplasms - metabolism | Cell Movement - genetics | Brain - metabolism | Glucuronosyltransferase - genetics | Matrix Metalloproteinase 9 - metabolism | rho-Associated Kinases - metabolism | Matrix Metalloproteinase 9 - genetics | Glioblastoma - metabolism | Hyaluronan Synthases | Spheroids, Cellular - drug effects | Matrix Metalloproteinase 1 - genetics | Polyethylene Glycols - pharmacology | Proto-Oncogene Proteins p21(ras) - metabolism | Extracellular Matrix - drug effects | Spheroids, Cellular - metabolism | rho-Associated Kinases - genetics | Up-Regulation - genetics | Cell Communication - genetics | Down-Regulation - drug effects | Down-Regulation - genetics | Brain - drug effects | Up-Regulation - drug effects | Cell Movement - drug effects | Glucuronosyltransferase - metabolism | Glioblastoma - pathology | Cell Communication - drug effects | Brain - pathology | Cell Line, Tumor | Cell Proliferation - drug effects | Hydrogels - pharmacology | Extracellular Matrix - pathology | Index Medicus
Journal Article
Journal Article