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FASEB Journal, ISSN 0892-6638, 11/2015, Volume 29, Issue 11, pp. 4713 - 4725
Hyperhomocysteinemia (HHcy) is prevalent in patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD). Emerging studies suggest that... 
Epigenetics | Matrix metalloproteinase | Renal fibrosis | 5-aza-2′-deoxycytidine | HOMOCYSTEINE | HUMAN-DISEASE | PROMOTER METHYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CYSTATHIONINE BETA-SYNTHASE | DIABETIC-NEPHROPATHY | HYDROGEN-SULFIDE | renal fibrosis | DIFFERENTIAL REGULATION | epigenetics | CELL BIOLOGY | BIOLOGY | matrix metalloproteinase | TISSUE INHIBITOR | DIETARY-FOLATE | HYPERTENSION | 5-aza-2'-deoxycytidine | Kidney - pathology | Galectin 3 - metabolism | Extracellular Matrix - metabolism | Hyperhomocysteinemia - metabolism | Acute Kidney Injury - genetics | Cytidine Monophosphate - pharmacology | Tissue Inhibitor of Metalloproteinase-2 - genetics | Extracellular Matrix - genetics | Tissue Inhibitor of Metalloproteinase-1 - metabolism | Tissue Inhibitor of Metalloproteinase-2 - metabolism | DNA Methylation | Kidney - metabolism | Matrix Metalloproteinase 9 - metabolism | Matrix Metalloproteinase 9 - genetics | Blood Pressure - drug effects | Collagen - genetics | Cystathionine beta-Synthase - genetics | Hyperhomocysteinemia - pathology | Acute Kidney Injury - drug therapy | Acute Kidney Injury - pathology | Cystathionine beta-Synthase - metabolism | Galectin 3 - genetics | DNA (Cytosine-5-)-Methyltransferases | Hyperhomocysteinemia - drug therapy | Mice, Knockout | Collagen - metabolism | Tissue Inhibitor of Metalloproteinase-1 - genetics | Animals | Cytidine Monophosphate - analogs & derivatives | Fibrosis | Hyperhomocysteinemia - genetics | Mice | Acute Kidney Injury - metabolism | Extracellular Matrix - pathology | Index Medicus | Research Communication
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 10/2013, Volume 110, Issue 43, pp. E4069 - E4078
The aryl hydrocarbon receptor (AhR) is a nuclear receptor that regulates xenobiotic metabolism and detoxification. Herein, we report a previously undescribed... 
Oxidized low density lipoprotein | Toxin metabolism | Retinal disease | Retinal pigment epithelium | DRUSEN | retinal disease | MULTIDISCIPLINARY SCIENCES | MOUSE | LOW-DENSITY-LIPOPROTEIN | toxin metabolism | oxidized low density lipoprotein | DIOXIN RECEPTOR | MODEL | PATHOGENESIS | GENE | LIVER | MICE | retinal pigment epithelium | PIGMENT | Receptors, Aryl Hydrocarbon - deficiency | Bruch Membrane - pathology | Humans | Middle Aged | Extracellular Matrix - metabolism | Male | Bruch Membrane - ultrastructure | Young Adult | Aging - genetics | RNA Interference | Pigment Epithelium of Eye - ultrastructure | Adult | Female | Lipoproteins, LDL - metabolism | Child | Disease Models, Animal | Tight Junctions - metabolism | Cell Line | Mice, Inbred C57BL | Receptors, Aryl Hydrocarbon - genetics | Microscopy, Electron | Aging - pathology | Mice, Knockout | Pigment Epithelium of Eye - metabolism | Macular Degeneration - metabolism | Animals | Macular Degeneration - genetics | Adolescent | Pigment Epithelium of Eye - pathology | Mice | Bruch Membrane - metabolism | Lipofuscin - metabolism | Lipoproteins, LDL - blood | Tight Junctions - pathology | Aging - metabolism | Macular Degeneration - pathology | Macular degeneration | Pathogenesis | Rodents | Hydrocarbons | T cell receptors | Metabolism | Low density lipoprotein | Index Medicus | Biological Sciences | PNAS Plus
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 1, pp. e16185 - e16185
Objective: Turnover of the extracellular matrix in all solid organs is governed mainly by a balance between the degrading matrix metalloproteinases (MMPs) and... 
PLASMA TISSUE INHIBITOR | METALLOPROTEINASE INHIBITION | LUNG-CANCER | INDEPENDENT PREDICTOR | LONG-TERM SURVIVAL | BIOLOGY | CARDIOVASCULAR-DISEASE | MATRIX-METALLOPROTEINASE-9 | SERUM | CONGESTIVE-HEART-FAILURE | E-DEFICIENT MICE | Myocardial Infarction - mortality | Prospective Studies | Humans | Mortality | Biomarkers - analysis | Extracellular Matrix - metabolism | Male | Risk | Cause of Death | Stroke - enzymology | Stroke - etiology | Aged | Stroke - mortality | Longitudinal Studies | Myocardial Infarction - etiology | Cohort Studies | Matrix Metalloproteinase 9 - blood | Myocardial Infarction - enzymology | Tissue Inhibitor of Metalloproteinase-1 - blood | Medical research | Physiological aspects | Medicine, Experimental | Research | Health aspects | Heart attack | Risk factors | Elderly people | Myocardial infarction | Health care | Matrix metalloproteinases | Heart attacks | Cardiomyopathy | Leukemia | Cardiovascular disease | Tissue inhibitor of metalloproteinase 1 | Confidence intervals | Mens health | Angiogenesis | Etiology | Rodents | Extracellular matrix | Standard deviation | Bioindicators | Cardiology | Growth factors | Heart failure | Cerebral infarction | Stroke | Codes | Health risks | Organs | Preventive medicine | Metabolism | Risk analysis | Gelatinase B | Serum levels | Correlation analysis | Men | Biomarkers | Infarction | Cardiovascular diseases | Health risk assessment | Elderly | Geriatrics | Cancer | Index Medicus | Clinical Medicine | Kirurgisk forskning | Medical and Health Sciences | Medicin och hälsovetenskap | MEDICIN | Surgery | Surgical research | Klinisk medicin | MEDICINE | Kirurgi | Ortopedi | Orthopaedics
Journal Article
Journal Article
Journal Article
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 08/2019, Volume 23, Issue 8, pp. 5737 - 5750
Intervertebral disc degeneration (IDD) is considered the primary culprit for low back pain. Although the underlying mechanisms remain unknown, hyperactive... 
intervertebral disc degeneration | NF‐κB | angiopoietin‐like protein 8 | inflammation | extracellular matrix | Proteins | Physiological aspects | Inflammation | Index Medicus | Original
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