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The Journal of clinical investigation, ISSN 1558-8238, 2017, Volume 127, Issue 5, pp. 1600 - 1612
The cardiac extracellular matrix (ECM) not only provides mechanical support, but also transduces essential molecular signals in health and disease... 
ISCHEMIA-REPERFUSION INJURY | MEDICINE, RESEARCH & EXPERIMENTAL | VOLUME OVERLOAD | HEART-FAILURE | CHRONIC PRESSURE-OVERLOAD | LEFT-VENTRICULAR DILATION | MATRICELLULAR PROTEINS | SMOOTH-MUSCLE-CELLS | ANGIOTENSIN-II | CARDIAC FIBROSIS | MICE LACKING OSTEOPONTIN | Inflammation - pathology | Leukocytes - pathology | Myocardium - immunology | Myocytes, Cardiac - immunology | Humans | Extracellular Matrix - immunology | Extracellular Matrix - metabolism | Stress, Mechanical | Heart Failure, Diastolic - metabolism | Myocardial Infarction - immunology | Leukocytes - immunology | Intercellular Signaling Peptides and Proteins - metabolism | Signal Transduction - immunology | Inflammation - metabolism | Myocardial Infarction - pathology | Myocardium - metabolism | Extracellular Matrix Proteins - metabolism | Myocardium - pathology | Inflammation - immunology | Myocardial Infarction - metabolism | Heart Failure, Diastolic - pathology | Myocytes, Cardiac - pathology | Animals | Extracellular Matrix Proteins - immunology | Heart Failure, Diastolic - immunology | Myocytes, Cardiac - metabolism | Extracellular Matrix - pathology | Leukocytes - metabolism | Intercellular Signaling Peptides and Proteins - immunology | Extracellular matrix | Care and treatment | Research | Regeneration (Biology) | Heart attack | Heart failure | Hypertension | Myocardial infarction | Heart attacks | Pathogenesis | Cardiomyocytes | Inflammation | Metabolism | Proteins | Ischemia | Collagen | Rodents | Fibroblasts | Plastics | Growth factors | Heart diseases | Binding sites
Journal Article
The Journal of pathology, ISSN 0022-3417, 12/2016, Volume 240, Issue 4, pp. 397 - 409
Journal Article
Journal Article
Cardiovascular research, ISSN 1755-3245, 2017, Volume 113, Issue 12, pp. 1453 - 1464
.... The right ventricular interstitium contains vascular cells, fibroblasts, and immune cells, enmeshed in a collagen-based matrix... 
Cardiac fibrosis | Arhhythmogenenic right ventricular cardiomyopathy | Extracellular matrix | Right ventricular failure | Pulmonary hypertension | PRESSURE-OVERLOAD | CARDIAC & CARDIOVASCULAR SYSTEMS | RECEPTOR BLOCKADE | PULMONARY ARTERIAL-HYPERTENSION | COLLAGEN-METABOLISM | ANGIOTENSIN-II | INFERIOR MYOCARDIAL-INFARCTION | RIGHT HEART-FAILURE | CARDIAC MAST-CELLS | ANTHRACYCLINE THERAPY | ENDOMYOCARDIAL BIOPSY | Humans | Heart Failure - physiopathology | Extracellular Matrix - metabolism | Hypertension, Pulmonary - physiopathology | Hypertrophy, Right Ventricular - etiology | Arrhythmogenic Right Ventricular Dysplasia - physiopathology | Hypertrophy, Right Ventricular - physiopathology | Ventricular Remodeling | Myocardial Infarction - pathology | Myocardium - metabolism | Hypertrophy, Right Ventricular - pathology | Myocardial Infarction - physiopathology | Ventricular Dysfunction, Right - physiopathology | Arrhythmogenic Right Ventricular Dysplasia - pathology | Arrhythmogenic Right Ventricular Dysplasia - metabolism | Heart Failure - etiology | Hypertrophy, Right Ventricular - metabolism | Ventricular Dysfunction, Right - metabolism | Extracellular Matrix Proteins - metabolism | Fibroblasts - metabolism | Myocardium - pathology | Heart Failure - metabolism | Hypertension, Pulmonary - metabolism | Heart Failure - pathology | Myocardial Infarction - metabolism | Fibroblasts - pathology | Animals | Ventricular Dysfunction, Right - etiology | Fibrosis | Extracellular Matrix - pathology | Hypertension, Pulmonary - pathology | Ventricular Dysfunction, Right - pathology | Ventricular Function, Right | Hypertension, Pulmonary - complications | Invited Spotlight Reviews
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2017, Volume 114, Issue 3, pp. 492 - 497
Journal Article
PloS one, ISSN 1932-6203, 2018, Volume 13, Issue 3, p. e0193967
.... Vitamin K dependent matrix Gla protein (MGP) plays a role in preserving microcirculatory integrity... 
POWERFUL PREDICTOR | GENERAL-POPULATION | MENAQUINONE-7 SUPPLEMENTATION | ARTERIAL STIFFNESS | MULTIDISCIPLINARY SCIENCES | HEART-FAILURE | K-DEPENDENT PROTECTION | VITAMIN-K | PRESERVED EJECTION FRACTION | BONE MORPHOGENETIC PROTEIN-4 | FILLING PRESSURE | Multivariate Analysis | Myocardial Ischemia - metabolism | Cardiomyopathy, Dilated - pathology | Cardiomyopathy, Dilated - surgery | Humans | Middle Aged | Male | Young Adult | Netherlands | Myocardium - metabolism | Ventricular Dysfunction, Left - pathology | Aged, 80 and over | Electrocardiography | Myocardial Ischemia - diagnostic imaging | Adult | Female | Extracellular Matrix Proteins - metabolism | Calcium-Binding Proteins - metabolism | Ventricular Dysfunction, Left - epidemiology | Heart Transplantation | Myocardium - pathology | Cardiomyopathy, Dilated - metabolism | Switzerland | Ventricular Dysfunction, Left - diagnostic imaging | Heart - diagnostic imaging | Myocardial Ischemia - pathology | Ventricular Dysfunction, Left - metabolism | Cardiomyopathy, Dilated - diagnostic imaging | Aged | Myocardial Ischemia - surgery | Cohort Studies | Physiological aspects | Development and progression | Calcium-binding proteins | Heart enlargement | Health aspects | Heart muscle | Health care | Heart | Nephrology | Cardiomyopathy | Antibodies | Interstitial cells | Epidemiology | Proteins | Ischemia | Measurement methods | Population | Blood pressure | Capillaries | Cardiology | Heart diseases | Enzyme-linked immunosorbent assay | Vitamin K | Hypertension | Research & development--R&D | Hospitals | Dilated cardiomyopathy | Calcification | Myocardium | Microvasculature | Ventricle | Integrity | Research & development | R&D
Journal Article