X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (16139) 16139
Book Chapter (33) 33
Conference Proceeding (2) 2
Book / eBook (1) 1
Newsletter (1) 1
Reference (1) 1
Web Resource (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (9279) 9279
humans (9215) 9215
extracellular signal-regulated map kinases - metabolism (8782) 8782
extracellular signal-regulated kinase (6003) 6003
phosphorylation (5774) 5774
signal transduction (5631) 5631
mice (5411) 5411
kinases (4408) 4408
cell biology (4206) 4206
proteins (3821) 3821
activation (3746) 3746
expression (3413) 3413
apoptosis (3309) 3309
cell line, tumor (3277) 3277
male (3137) 3137
map kinase (3021) 3021
gene expression (2991) 2991
biochemistry & molecular biology (2956) 2956
female (2689) 2689
oncology (2646) 2646
cells, cultured (2579) 2579
cancer (2488) 2488
cell proliferation (2482) 2482
rats (2424) 2424
research article (2324) 2324
multidisciplinary sciences (2294) 2294
signal transduction - drug effects (2241) 2241
medicine (2227) 2227
cell line (2127) 2127
science (2017) 2017
proto-oncogene proteins c-akt - metabolism (1874) 1874
signaling (1837) 1837
research (1776) 1776
inhibition (1739) 1739
rodents (1729) 1729
extracellular signal-regulated map kinases - genetics (1638) 1638
phosphorylation - drug effects (1612) 1612
inflammation (1576) 1576
map kinase signaling system (1487) 1487
cell proliferation - drug effects (1486) 1486
map kinase signaling system - drug effects (1486) 1486
biology (1427) 1427
erk (1402) 1402
gene-expression (1396) 1396
analysis (1391) 1391
akt protein (1380) 1380
mutation (1341) 1341
cells (1311) 1311
genetic aspects (1299) 1299
mice, inbred c57bl (1297) 1297
extracellular signal-regulated map kinases - antagonists & inhibitors (1282) 1282
proliferation (1275) 1275
blotting, western (1243) 1243
physiological aspects (1240) 1240
physiology (1232) 1232
apoptosis - drug effects (1224) 1224
enzyme activation (1217) 1217
immunology (1206) 1206
growth (1201) 1201
tumors (1187) 1187
p38 mitogen-activated protein kinases - metabolism (1169) 1169
cell cycle (1144) 1144
neurosciences (1134) 1134
pathways (1126) 1126
rna, messenger - metabolism (1102) 1102
cell growth (1098) 1098
differentiation (1070) 1070
transfection (1069) 1069
transcription factors (1058) 1058
health aspects (1054) 1054
cytokines (1047) 1047
pathway (1038) 1038
biochemistry (1037) 1037
metastasis (1035) 1035
oxidative stress (1022) 1022
signal transduction - physiology (1022) 1022
mice, knockout (1005) 1005
protein kinases (966) 966
in-vitro (941) 941
phosphatidylinositol 3-kinases - metabolism (934) 934
cell migration (925) 925
rats, sprague-dawley (915) 915
rna, messenger - genetics (911) 911
growth factors (909) 909
nf-kappa b - metabolism (909) 909
rna interference (909) 909
protein (908) 908
up-regulation (905) 905
enzyme activation - drug effects (894) 894
stem cells (894) 894
disease models, animal (893) 893
activated protein-kinase (890) 890
protein kinase inhibitors - pharmacology (888) 888
nf-kappa-b (886) 886
kinase (865) 865
time factors (857) 857
transcription (857) 857
medicine, research & experimental (850) 850
down-regulation (838) 838
cell survival (836) 836
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (16136) 16136
Japanese (93) 93
Chinese (58) 58
French (10) 10
Norwegian (6) 6
Russian (4) 4
Portuguese (2) 2
Danish (1) 1
Dutch (1) 1
German (1) 1
Italian (1) 1
Korean (1) 1
Spanish (1) 1
Ukrainian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Leukemia, ISSN 1476-5551, 2011, Volume 25, Issue 7, pp. 1080 - 1094
The Ras/Raf/mitogen-activated protein kinase (MEK)/extracellular signal-regulated kinase (ERK... 
targeted therapy | Ras | therapeutic sensitivity | Raf | resistance | ERK | ABROGATE CYTOKINE DEPENDENCY | INITIATION-FACTOR 4E | ACUTE MYELOID-LEUKEMIA | KINASE INHIBITOR PROTEIN | DRUG-INDUCED APOPTOSIS | BONE-MARROW MICROENVIRONMENT | ONCOLOGY | ACUTE LYMPHOBLASTIC-LEUKEMIA | CHRONIC LYMPHOCYTIC-LEUKEMIA | MURINE HEMATOPOIETIC-CELLS | HEMATOLOGY | SIGNAL-REGULATED KINASE | ras Proteins - genetics | MAP Kinase Signaling System - physiology | Mitogen-Activated Protein Kinase Kinases - genetics | Apoptosis - drug effects | raf Kinases - antagonists & inhibitors | Humans | Neoplasm Proteins - physiology | Mitogen-Activated Protein Kinase Kinases - physiology | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Neoplasm Proteins - antagonists & inhibitors | Antineoplastic Agents - therapeutic use | Molecular Targeted Therapy | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Extracellular Signal-Regulated MAP Kinases - genetics | Gene Expression Regulation, Leukemic - genetics | raf Kinases - physiology | MAP Kinase Signaling System - genetics | Drug Design | Antineoplastic Agents - pharmacology | Extracellular Signal-Regulated MAP Kinases - physiology | Neoplasm Proteins - genetics | raf Kinases - genetics | ras Proteins - physiology | Cell Division - genetics | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | ras Proteins - antagonists & inhibitors | Gene Expression Regulation, Leukemic - drug effects | Leukemia - drug therapy | Cell Division - drug effects | Phosphatidylinositol 3-Kinases - genetics | Drug Resistance, Neoplasm - genetics | MAP Kinase Signaling System - drug effects | Models, Biological | Phosphatidylinositol 3-Kinases - physiology | Apoptosis - physiology | Drug Resistance, Neoplasm - physiology | Drug Resistance, Neoplasm - drug effects | Chemotherapy | Extracellular signal-regulated kinases | Leukemia | Physiological aspects | Genetic aspects | Research | Drug therapy | Health aspects | Mitogen-activated protein kinases | Cancer
Journal Article
by Zhang, Y and Li, R and Meng, Y and Li, S and Donelan, W and Zhao, Y and Qi, L and Zhang, M and Wang, X and Cui, T and Yang, L.-J and Tang, D
Diabetes (New York, N.Y.), ISSN 1939-327X, 2013, Volume 63, Issue 2, pp. 514 - 525
.... This effect was possibly mediated by irisin-induced phosphorylation of the p38 mitogen-activated protein kinase (p38 MAPK... 
OBESITY | GENE | ENDOCRINOLOGY & METABOLISM | MUSCLE | RECEPTOR | PROLIFERATION | DIFFERENTIATION | EXPRESSION | FAT-CELL | EXERCISE | ADIPOSE-TISSUE | MAP Kinase Signaling System - physiology | Nitriles - pharmacology | Adipose Tissue, White - metabolism | Caenorhabditis elegans Proteins - metabolism | Adipocytes - cytology | Male | Adipocytes - drug effects | Extracellular Signal-Regulated MAP Kinases - metabolism | Recombinant Proteins | Extracellular Signal-Regulated MAP Kinases - genetics | Pichia - metabolism | Membrane Transport Proteins - genetics | Dietary Fats | Membrane Transport Proteins - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Butadienes - pharmacology | Fibronectins - pharmacology | Fibronectins - administration & dosage | Mice, Inbred C57BL | Rats | p38 Mitogen-Activated Protein Kinases - genetics | Imidazoles - pharmacology | 3T3-L1 Cells | Rats, Sprague-Dawley | Animals | Adipocytes - metabolism | Pichia - genetics | Protein Binding | Adipose Tissue, Brown - drug effects | Adipose Tissue, Brown - metabolism | Fibronectins - genetics | Mice | Pyridines - pharmacology | Mutation | Mitochondrial Uncoupling Proteins | Caenorhabditis elegans Proteins - genetics | Adipose Tissue, White - drug effects | Physiological research | Cellular signal transduction | Research | Identification and classification | Membrane proteins
Journal Article
Science (American Association for the Advancement of Science), ISSN 0036-8075, 02/2017, Volume 355, Issue 6327, pp. 836 - 842
Journal Article
Journal Article
Oncogene, ISSN 1476-5594, 2007, Volume 26, Issue 22, pp. 3291 - 3310
Journal Article
The Journal of pharmacology and experimental therapeutics, ISSN 1521-0103, 2015, Volume 352, Issue 2, pp. 346 - 357
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 2012, Volume 287, Issue 42, pp. 35576 - 35588
Tetrandrine, a bisbenzylisoquinoline alkaloid isolated from the broadly used Chinese medicinal herb Stephaniae tetrandrae, exhibits potent antitumor effects... 
CYTOCHROME-C | APOPTOSIS | COLON-CANCER CELLS | ACTIVATION | THERAPY | PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | MITOCHONDRIA | GROWTH | DEATH | PERMEABILIZATION | Transcription, Genetic - drug effects | Reactive Oxygen Species - metabolism | Microtubule-Associated Proteins - genetics | Humans | Ubiquitin-Activating Enzymes - biosynthesis | Male | Extracellular Signal-Regulated MAP Kinases - metabolism | Neoplasm Proteins - metabolism | Extracellular Signal-Regulated MAP Kinases - genetics | Autophagy - drug effects | Benzylisoquinolines - chemistry | Dose-Response Relationship, Drug | Carcinoma, Hepatocellular - drug therapy | MAP Kinase Signaling System - genetics | Mitochondria - genetics | Carcinoma, Hepatocellular - genetics | Liver Neoplasms - pathology | Autophagy - genetics | Gene Expression Regulation, Neoplastic - drug effects | Neoplasm Proteins - genetics | Stephania tetrandra - chemistry | Antineoplastic Agents, Phytogenic - pharmacokinetics | Benzylisoquinolines - pharmacology | Gene Expression Regulation, Neoplastic - genetics | Ubiquitin-Activating Enzymes - genetics | Liver Neoplasms - genetics | Liver Neoplasms - drug therapy | Antineoplastic Agents, Phytogenic - chemistry | Mitochondria - metabolism | Mitochondria - pathology | Microtubule-Associated Proteins - biosynthesis | Hep G2 Cells | Xenograft Model Antitumor Assays | Autophagy-Related Protein 7 | Animals | MAP Kinase Signaling System - drug effects | Mice, Nude | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Mice | Mice, Inbred BALB C | Transcription, Genetic - genetics | Carcinoma, Hepatocellular - metabolism | Gene Regulation | Cancer Therapy | Autophagy-related Gene 7 (ATG7) | Tetrandrine | Reactive Oxygen Species (ROS) | Signal Transduction | Autophagy | Anticancer Drug | ERK | Hepatocellular Carcinoma
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 12/2011, Volume 286, Issue 50, pp. 42981 - 42991
Journal Article