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Frontiers in Cellular Neuroscience, ISSN 1662-5102, 01/2012, Volume 6, Issue JANUARY
The potency of GABA is vitally important for its primary role in activating GABA(A) receptors and acting as an inhibitory neurotransmitter. Although numerous... 
GABA | Neurons | Receptor | Synaptic and extra synaptic receptors | ALPHA-SUBUNIT | synaptic and extrasynaptic receptors | neurons | NEUROSCIENCES | EPSILON-SUBUNIT | DIRECT BINDING | DELTA-SUBUNIT | SUBUNIT MESSENGER-RNAS | GABA(A) receptor | GAMMA-AMINOBUTYRIC-ACID | RAT-BRAIN | TONIC INHIBITION | BETA-SUBUNIT | IMMUNOCYTOCHEMICAL DISTRIBUTION
Journal Article
BIOCHEMICAL PHARMACOLOGY, ISSN 0006-2952, 08/2012, Volume 84, Issue 4, pp. 549 - 557
Ionotropic GABA(A) receptors are a highly heterogenous population of receptors assembled from a combination of multiple subunits. The aims of this study were... 
ACTIVATION | SUSCEPTIBILITY | AMINOBUTYRIC ACID(A) RECEPTORS | GABA binding site | A RECEPTORS | INTERNATIONAL UNION | INHIBITION | Site-directed mutagenesis | PHARMACOLOGY | MOUSE MODEL | GABA | PHARMACOLOGY & PHARMACY | OVARIAN CYCLE | Extrasynaptic GABA(A) receptors | delta-Subunit | SUBUNIT
Journal Article
Neurochemical Research, ISSN 0364-3190, 10/2014, Volume 39, Issue 10, pp. 1942 - 1947
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 07/2015, Volume 764, pp. 497 - 507
Novel 2,3-benzodiazepine and related isoquinoline derivatives, substituted at position 1 with a 2-benzothiophenyl moiety, were synthesized to produce compounds... 
Benzothiophene | Nootropic agents | GABA | GABA A antagonist | Isoquinoline | Extrasynaptic receptors | 2,3-Benzodiazepine | Object recognition test | SUBTYPES | GARA | SUBUNIT COMPOSITION | A RECEPTORS | PYRAMIDAL NEURONS | GABA(A) antagonist | PHARMACOLOGY | ANIMAL-MODELS | ION-CHANNEL | PHARMACOLOGY & PHARMACY | RAT-BRAIN | ANTAGONISTS | TONIC INHIBITION | Capillary Permeability | Seizures - prevention & control | Benzodiazepines - chemical synthesis | Nootropic Agents - metabolism | Humans | Motor Activity - drug effects | Male | Structure-Activity Relationship | GABA-A Receptor Antagonists - metabolism | Anticonvulsants - pharmacology | Seizures - chemically induced | Dose-Response Relationship, Drug | HEK293 Cells | Receptors, GABA-A - drug effects | Behavior, Animal - drug effects | Molecular Structure | Benzodiazepines - metabolism | Disease Models, Animal | GABA-A Receptor Antagonists - pharmacology | Benzodiazepines - pharmacology | Anticonvulsants - chemical synthesis | Xenopus laevis | Anticonvulsants - metabolism | Nootropic Agents - chemical synthesis | Rats, Sprague-Dawley | Anticonvulsants - toxicity | Blood-Brain Barrier - metabolism | GABA-A Receptor Antagonists - chemical synthesis | Nootropic Agents - toxicity | Animals | Recognition (Psychology) - drug effects | Benzodiazepines - toxicity | Receptors, GABA-A - genetics | Mice | Pentylenetetrazole | Receptors, GABA-A - metabolism | GABA-A Receptor Antagonists - toxicity | Nootropic Agents - pharmacology
Journal Article
BRITISH JOURNAL OF PHARMACOLOGY, ISSN 0007-1188, 02/2014, Volume 171, Issue 4, pp. 985 - 994
Journal Article
Neuropharmacology, ISSN 0028-3908, 2015, Volume 88, pp. 24 - 35
γ-Aminobutyric acid type A receptors that contain the δ subunit (δGABA receptors) are expressed in multiple types of neurons throughout the central nervous... 
receptor | Disease | Expression | Plasticity | Behavior | δGABA | Tonic inhibition | MEDIATED TONIC INHIBITION | DORSOLATERAL PREFRONTAL CORTEX | EXTRASYNAPTIC GABA(A) RECEPTORS | CYCLE-LINKED CHANGES | NEUROSCIENCES | delta GABA(A) receptor | CEREBELLAR GRANULE CELLS | DELTA-SUBUNIT | SUBUNIT MESSENGER-RNAS | A RECEPTOR | MOUSE MODEL | PHARMACOLOGY & PHARMACY | RAT-BRAIN
Journal Article
Journal of Ethnopharmacology, ISSN 0378-8741, 06/2015, Volume 171, pp. 264 - 272
Ethnopharmacological relevance Withania somnifera (WS) has been traditionally used in Ayurvedic medicine as a remedy for debility, stress, nervous exhaustion,... 
Synaptic receptors | GABAergic signaling | GABA | Extrasynaptic receptors | Ashwagandha
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 01/2015, Volume 112, Issue 4, pp. 1214 - 1219
GABA(A)-receptor-based interneuron circuitry is essential for higher order function of the human nervous system and is implicated in schizophrenia, depression,... 
COMPLEX | PROTEIN | CYTOSKELETON | INHIBITORY SYNAPSES | NEUROFASCIN | MULTIDISCIPLINARY SCIENCES | extrasynaptic membrane | PLASMA-MEMBRANE | GABARAP | GABA(A) receptor endocytosis | AXON INITIAL SEGMENT | GABAergic synapses | ASSOCIATION | giant ankyrin-G | CLATHRIN
Journal Article
Journal of Molecular Neuroscience, ISSN 0895-8696, 02/2019, Volume 67, Issue 2, pp. 343 - 351
GABA receptors are the major inhibitory neurotransmitter receptor in the human brain. The receptors are assembled from combination of protein subunits in... 
GABA | Extrasynaptic | receptors | Cognitive dysfunction | Tonic inhibition
Journal Article
JOURNAL OF MOLECULAR NEUROSCIENCE, ISSN 0895-8696, 02/2019, Volume 67, Issue 2, pp. 343 - 351
GABA(A) receptors are the major inhibitory neurotransmitter receptor in the human brain. The receptors are assembled from combination of protein subunits in... 
TS65DN MOUSE | AUTISM | SUBTYPES | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | AMINOBUTYRIC ACID(A) RECEPTORS | HIPPOCAMPAL-NEURONS | NEUROSCIENCES | Tonic inhibition | GABA(A) receptors | Extrasynaptic | ALPHA-5 SUBUNIT | DOWN-SYNDROME | INVERSE AGONIST | Cognitive dysfunction | BRAIN
Journal Article
Epilepsia, ISSN 0013-9580, 04/2015, Volume 56, Issue 4, pp. 647 - 657
ObjectiveWithin its range of therapeutic plasma concentrations, the anticonvulsant retigabine (ezogabine) is believed to selectively act on Kv7 channels. Here,... 
Kv7 channels | Seizure-like activity | Extrasynaptic GABA A receptors | Retigabine | POTASSIUM CHANNELS | CLINICAL NEUROLOGY | EZOGABINE | A RECEPTORS | TRANSMISSION | INHIBITION | CALCIUM-CHANNELS | EPILEPTIFORM ACTIVITY | NEURONS | KCNQ | Extrasynaptic GABA(A) receptors | Full‐Length Original Research | Seizure‐like activity | Extrasynaptic GABAA receptors
Journal Article