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1. Full Text Polarized Vascular Endothelial Growth Factor Secretion by Human Retinal Pigment Epithelium and Localization of Vascular Endothelial Growth Factor Receptors on the Inner Choriocapillaris : Evidence for a Trophic Paracrine Relation
by Blaauwgeers, Harriet G. T and Holtkamp, Gertjan M and Rutten, Hugo and Witmer, Antonella N and Koolwijk, Pieter and Partanen, Taina A and Alitalo, Kari and Kroon, Marielle E and Kijlstra, Aize and van Hinsbergh, Victor W. M and Schlingemann, Reinier O
American Journal of Pathology, ISSN 0002-9440, 08/1999, Volume 155, Issue 2, pp. 421 - 428
The retinal pigment epithelium (RPE) maintains the choriocapillaris (CC) in the normal eye and is involved in the pathogenesis of choroidal neovascularization... 
IN-VITRO | PERMEABILITY FACTOR | INCREASED EXPRESSION | ANGIOGENESIS | SUBRETINAL NEOVASCULARIZATION | VEGF | PDGF | PATHOLOGY | CELLS PRODUCE | PROTEINS | AGE | Immunohistochemistry | Receptors, Vascular Endothelial Growth Factor | Vascular Endothelial Growth Factor A | Retina - metabolism | Lymphokines - secretion | Vascular Endothelial Growth Factors | Humans | Receptors, Cell Surface - analysis | Vascular Endothelial Growth Factor Receptor-3 | Endothelial Growth Factors - secretion | Vascular Endothelial Growth Factor Receptor-1 | Cell Hypoxia | Antibodies, Monoclonal - analysis | Epithelium - anatomy & histology | Proto-Oncogene Proteins - analysis | Choroid - anatomy & histology | Adult | Receptor Protein-Tyrosine Kinases - analysis | Child | Cell Line | Pigment Epithelium of Eye - secretion | Choroid - metabolism | Paracrine Communication | Cells, Cultured | Choroid - blood supply | Retina - anatomy & histology | Animals | Receptors, Growth Factor - analysis | Adolescent | Macaca fascicularis - anatomy & histology | Index Medicus | Abridged Index Medicus | Regular
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2. Full Text Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab
by Papadopoulos, Nicholas and Martin, Joel and Ruan, Qin and Rafique, Ashique and Rosconi, Michael P and Shi, Ergang and Pyles, Erica A and Yancopoulos, George D and Stahl, Neil and Wiegand, Stanley J
Angiogenesis, ISSN 0969-6970, 6/2012, Volume 15, Issue 2, pp. 171 - 185
Pharmacological inhibition of VEGF-A has proven to be effective in inhibiting angiogenesis and vascular leak associated with cancers and various eye diseases.... 
Biomedicine | Age-related macular degeneration | Cancer Research | Oncology | Affinity | Ophthalmology | VEGF receptor | Cardiology | Aflibercept | Placental growth factor | Biomedicine general | Cell Biology | EYE DISEASE | MACULAR DEGENERATION | PHASE-II | CHOROIDAL NEOVASCULARIZATION | FACTOR THERAPY | IN-VITRO | PROLIFERATIVE DIABETIC-RETINOPATHY | PATHOLOGICAL CONDITIONS | RETINAL DISEASES | PERIPHERAL VASCULAR DISEASE | INTRAVITREAL BEVACIZUMAB | Angiogenesis Inhibitors - immunology | Receptors, Vascular Endothelial Growth Factor | Vascular Endothelial Growth Factor B - antagonists & inhibitors | Recombinant Fusion Proteins - pharmacology | Endothelial Cells - metabolism | Humans | Angiogenesis Inhibitors - pharmacology | Vascular Endothelial Growth Factor B - immunology | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Vascular Endothelial Growth Factor A - immunology | Vascular Endothelial Growth Factor Receptor-1 - metabolism | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Vascular Endothelial Growth Factor Receptor-2 - immunology | Enzyme Activation - drug effects | Bevacizumab | Endothelial Cells - immunology | Vascular Endothelial Growth Factor B - metabolism | Antibodies, Monoclonal, Humanized - pharmacology | HEK293 Cells | Ranibizumab | Vascular Endothelial Growth Factor Receptor-1 - immunology | Antibodies, Monoclonal, Humanized - immunology | Index Medicus | Original Paper
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3. GABA in the retina and central visual system
by Mize, R. Ranney and Marc, R. E and Sillito, A. M
1992, Progress in brain research, ISBN 9780444814463, Volume 90., xiii, 545
GABA | Retina | Visual cortex | Receptors | Physiological effect | Visual pathways
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4. Full Text Regulation of Notch1 and Dll4 by Vascular Endothelial Growth Factor in Arterial Endothelial Cells: Implications for Modulating Arteriogenesis and Angiogenesis
by Zhao-Jun Liu and Takashi Shirakawa and Yan Li and Akinobu Soma and Masahiro Oka and G. Paolo Dotto and Ronald M. Fairman and Omaida C. Velazquez and Meenhard Herlyn
Molecular and Cellular Biology, ISSN 0270-7306, 01/2003, Volume 23, Issue 1, pp. 14 - 25
Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
ACTIVATION | PROTEIN-KINASE-B | GENE | PHOSPHATIDYLINOSITOL 3-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | RECEPTOR | MICE | DIFFERENTIATION | LIGAND | EXPRESSION | DROSOPHILA EYE | CELL BIOLOGY | Endothelium, Vascular - cytology | Endothelial Growth Factors - metabolism | Vascular Endothelial Growth Factors | Humans | Protein-Serine-Threonine Kinases | Fibroblast Growth Factor 2 - pharmacology | Cell Survival - genetics | Endothelium, Vascular - drug effects | Endothelial Growth Factors - pharmacology | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Vascular Endothelial Growth Factor Receptor-2 - genetics | Phosphatidylinositol 3-Kinases - drug effects | Lymphokines - metabolism | Cell Survival - drug effects | Vascular Endothelial Growth Factor Receptor-2 - drug effects | Signal Transduction | Membrane Proteins - genetics | Enzyme Inhibitors - pharmacology | Solubility | Recombinant Proteins - chemistry | Cell Division - drug effects | Lymphokines - chemistry | Vascular Endothelial Growth Factor Receptor-1 - drug effects | Intercellular Signaling Peptides and Proteins - pharmacology | Transcription Factors | Vascular Endothelial Growth Factor A | Intercellular Signaling Peptides and Proteins - chemistry | Receptors, Cell Surface | Endothelial Growth Factors - chemistry | Phosphatidylinositol 3-Kinases - metabolism | Arteries - cytology | Endothelium, Vascular - physiology | Intercellular Signaling Peptides and Proteins - metabolism | Receptors, Notch | Arteries - physiology | Fibroblast Growth Factor 2 - metabolism | Flavonoids - pharmacology | Membrane Proteins - metabolism | Lymphokines - pharmacology | Vascular Endothelial Growth Factor Receptor-1 - genetics | Cell Division - genetics | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - drug effects | Cells, Cultured | Gene Expression Regulation | Intracellular Signaling Peptides and Proteins | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Proto-Oncogene Proteins - genetics | Vascular Endothelial Growth Factor Receptor-1 - metabolism | Recombinant Proteins - genetics | Recombinant Proteins - pharmacology | Proto-Oncogene Proteins c-akt | Receptor, Notch1 | Neovascularization, Physiologic | Receptor, Notch4 | Index Medicus | Cell Growth and Development
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5. Full Text Sutureless fixation of amniotic membrane for therapy of ocular surface disorders
by Kotomin, Ilya and Valtink, Monika and Hofmann, Kai and Hofmann, Kai and Frenzel, Annika and Morawietz, Henning and Morawietz, Henning and Werner, Carsten and Funk, Richard H. W and Engelmann, Katrin and Engelmann, Katrin
PLoS ONE, ISSN 1932-6203, 05/2015, Volume 10, Issue 5, pp. e0125035 - e0125035
Amniotic membrane is applied to the diseased ocular surface to stimulate wound healing and tissue repair, because it releases supportive growth factors and... 
CORNEA | CELLS | ANGIOGENESIS | KERATOPATHY | MULTIDISCIPLINARY SCIENCES | GROWTH-FACTOR | TRANSPLANTATION | Corneal Diseases - therapy | Humans | Middle Aged | Male | Nerve Growth Factors - metabolism | Vascular Endothelial Growth Factor A - metabolism | Epithelium, Corneal - pathology | Vascular Endothelial Growth Factor A - genetics | Equipment Design | Amnion - metabolism | Aged, 80 and over | Fibroblast Growth Factor 2 - metabolism | Hepatocyte Growth Factor - genetics | Adult | Female | Cornea - pathology | Eye Proteins - genetics | Biological Dressings | Corneal Diseases - pathology | Biomarkers - metabolism | Gene Expression | Serpins - genetics | Serpins - metabolism | Hepatocyte Growth Factor - metabolism | Ophthalmologic Surgical Procedures - instrumentation | Pilot Projects | Eye Proteins - metabolism | Fibroblast Growth Factor 2 - genetics | Nerve Growth Factors - genetics | Amnion - surgery | Aged | Ophthalmologic Surgical Procedures - methods | Fibroblast growth factors | Cytokines | RNA | Vascular endothelial growth factor | Intervention | Fibroblast growth factor | Membranes | Cornea | Pigment ePithelium-derived factor | Disorders | Transplantation | mRNA | Design | Angiogenesis | Biological effects | Prototypes | Surgery | Sutures | Ultrasonic testing | Growth factors | Fibroblast growth factor 2 | Wound healing | Hepatocyte growth factor | Inflammation | Epithelium | Immunological tolerance | Endothelium | Mounting | Amniotic membrane | Ulcers | Binding sites | Histochemistry | Index Medicus
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6. Full Text Ten years of anti-vascular endothelial growth factor therapy
by Ferrara, Napoleone and Adamis, Anthony P
Nature Reviews Drug Discovery, ISSN 1474-1776, 06/2016, Volume 15, Issue 6, pp. 385 - 403
The targeting of vascular endothelial growth factor A (VEGFA), a crucial regulator of both normal and pathological angiogenesis, has revealed innovative... 
ANTI-VEGF ANTIBODY | RECEPTOR TYROSINE KINASES | MACULAR EDEMA SECONDARY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | RANDOMIZED PHASE-III | HUMANIZED MONOCLONAL-ANTIBODY | BEVACIZUMAB PLUS IRINOTECAN | PHARMACOLOGY & PHARMACY | VASCULAR-PERMEABILITY FACTOR | METASTATIC COLORECTAL-CANCER | RENAL-CELL CARCINOMA | FACTOR-INDUCED ANGIOGENESIS | Time Factors | Neovascularization, Pathologic - drug therapy | Humans | Angiogenesis Inhibitors - therapeutic use | Antibodies, Monoclonal - therapeutic use | Neoplasms - blood supply | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Neoplasms - drug therapy | Molecular targeted therapy | Care and treatment | Innovations | Eye diseases | Vascular endothelial growth factor | Identification and classification | Cancer | Forecasts and trends | Health aspects | Protein therapy | Index Medicus
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7. Full Text Serum growth factor analysis in dry eye syndrome
by Bradley, Jay C and Bradley, Rachael H and McCartney, David L and Mannis, Mark J
Clinical & Experimental Ophthalmology, ISSN 1442-6404, 11/2008, Volume 36, Issue 8, pp. 717 - 720
Background:  To perform a comprehensive serum growth factor analysis in dry eye syndrome patients and to compare this with matched controls. Methods:  Six... 
growth factor | anterior segment | autologous serum | dry eye syndrome | Dry eye syndrome | Autologous serum | Anterior segment | Growth factor | DROPS | MAINTENANCE | DISEASE | OPHTHALMOLOGY | EYEDROPS | Fibroblast Growth Factor 7 - blood | Proto-Oncogene Proteins c-sis | Humans | Middle Aged | Vascular Endothelial Growth Factor A - blood | Brain-Derived Neurotrophic Factor - blood | Insulin-Like Growth Factor I - analysis | Fibroblast Growth Factor 2 - blood | Case-Control Studies | Epidermal Growth Factor - blood | Intercellular Signaling Peptides and Proteins - blood | Nerve Growth Factor - blood | Hepatocyte Growth Factor - blood | Dry Eye Syndromes - blood | Platelet-Derived Growth Factor - analysis | Aged, 80 and over | Ophthalmic Solutions | Female | Transforming Growth Factor beta2 - blood | Aged | Transforming Growth Factor beta1 - blood | Dry Eye Syndromes - etiology | Nerve Growth Factor, blood | Platelet-Derived Growth Factor, analysis | Intercellular Signaling Peptides and Proteins, blood | Transforming Growth Factor beta1, blood | Transforming Growth Factor beta2, blood | Dry Eye Syndromes, etiology | Fibroblast Growth Factor 7, blood | Brain-Derived Neurotrophic Factor, blood | Insulin-Like Growth Factor I, analysis | Fibroblast Growth Factor 2, blood | Hepatocyte Growth Factor, blood | Vascular Endothelial Growth Factor A, blood | Epidermal Growth Factor, blood | Dry Eye Syndromes, blood | Peptides | Analysis | Eye diseases | Nerve growth factor | Ophthalmology | Growth factors | Vascular endothelial growth factor | Index Medicus
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8. Full Text Proapoptotic PEDF functional peptides inhibit prostate tumor growth—A mechanistic study
by Gong, Qing and Qiu, Shaopeng and Li, Shuai and Ma, Yuedong and Ma, Jianxing and Chen, Mingyuan and Yao, Yachao and Che, Di and Feng, Juan and Cai, Weibin and Yang, Xia and Yang, Zhonghan and Gao, Guoquan
Biochemical Pharmacology, ISSN 0006-2952, 12/2014, Volume 92, Issue 3, pp. 425 - 437
PEDF inhibits tumor growth via anti-angiogenic activity; however, the direct effect of PEDF on prostate carcinoma and its functional epitope as well as the... 
Prostate carcinoma | PEDF | Epitope | PPARγ | Apoptosis | ACTIVATED RECEPTOR-GAMMA | CANCER CELLS | LUNG-CARCINOMA | PPAR gamma | ANTI-ANGIOGENIC ACTIVITY | PIGMENT-EPITHELIUM | EPITHELIUM-DERIVED FACTOR | ENDOTHELIAL-CELLS | PPAR-GAMMA | PHARMACOLOGY & PHARMACY | NF-KAPPA-B | EXPRESSION | Eye Proteins - immunology | Receptors, Laminin - metabolism | Prostatic Neoplasms - metabolism | Up-Regulation | Fas Ligand Protein - metabolism | Apoptosis - drug effects | Humans | Caspase 8 - metabolism | Neovascularization, Pathologic | Eye Proteins - chemistry | Molecular Sequence Data | Apoptosis - genetics | Male | NF-kappa B - metabolism | Peptide Fragments - pharmacology | Nerve Growth Factors - metabolism | PPAR gamma - metabolism | Serpins - chemistry | Base Sequence | Peptide Fragments - immunology | Antineoplastic Agents - pharmacology | Eye Proteins - genetics | Peptide Fragments - genetics | Prostatic Neoplasms - drug therapy | Recombinant Proteins - metabolism | Prostatic Neoplasms - pathology | Serpins - genetics | Serpins - metabolism | Models, Molecular | Nerve Growth Factors - chemistry | Nerve Growth Factors - immunology | Recombinant Proteins - genetics | Epitopes | Serpins - immunology | Xenograft Model Antitumor Assays | Animals | Eye Proteins - metabolism | Recombinant Proteins - immunology | Nerve Growth Factors - genetics | Cell Line, Tumor | Protein Conformation | Mice, Inbred BALB C | Care and treatment | Peptides | Prostate cancer | Cancer | Tumors | Index Medicus
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9. Full Text Role of Cortical Tension in Bleb Growth
by Jean-Yves Tinevez and Ulrike Schulze and Guillaume Salbreux and Julia Roensch and Jean-François Joanny and Ewa Paluch
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2009, Volume 106, Issue 44, pp. 18581 - 18586
Blebs are spherical membrane protrusions often observed during cell migration, cell spreading, cytokinesis, and apoptosis, both in cultured cells and in vivo.... 
Cell motility | Cell growth | Germ cells | Actins | Cell membranes | Laser ablation | Animal cells | Cells | Cytoplasm | P branes | ACTIN CORTEX | REQUIREMENTS | ATOMIC-FORCE MICROSCOPY | MYOSIN | MULTIDISCIPLINARY SCIENCES | TUMOR-CELL INVASION | PLASMA-MEMBRANE | CYTOSKELETAL DYNAMICS | MECHANICAL-PROPERTIES | FLOW | MOTILITY | Cell Line | Animals | Lasers | Models, Biological | Actins - metabolism | Elasticity | Myosins - metabolism | Cytoskeleton - physiology | Mice | Pressure | Cell Surface Extensions - physiology | Blisters | Cell physiology | Diagnosis | Research | Proteins | Cell culture | Membranes | Cysts | Hernias | Biochemistry | Cell adhesion & migration | Apoptosis | Index Medicus | Biological Sciences
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10. Full Text VEGF ameliorates pulmonary hypertension through inhibition of endothelial apoptosis in experimental lung fibrosis in rats
by Farkas, Laszlo and Farkas, Daniela and Ask, Kjetil and Möller, Antje and Gauldie, Jack and Margetts, Peter and Inman, Mark and Kolb, Martin
Journal of Clinical Investigation, ISSN 0021-9738, 05/2009, Volume 119, Issue 5, pp. 1298 - 1311
Idiopathic pulmonary fibrosis (IPF) can lead to the development of secondary pulmonary hypertension (PH) and ultimately death. Despite this known association,... 
MEDICINE, RESEARCH & EXPERIMENTAL | EPITHELIUM-DERIVED FACTOR | GROWTH-FACTOR-BETA | ANGIOGENESIS | ARTERIAL-HYPERTENSION | DISEASE | SMOOTH-MUSCLE-CELLS | PROLIFERATION | GENE-TRANSFER | EXPRESSION | PIGMENT-EPITHELIUM | Genetic Therapy | Idiopathic Pulmonary Fibrosis - therapy | Apoptosis - drug effects | Gene Expression - genetics | Humans | Transforming Growth Factor beta1 - metabolism | Caspase 3 - metabolism | Hypertension, Pulmonary - physiopathology | Microvessels - pathology | Idiopathic Pulmonary Fibrosis - chemically induced | Nerve Growth Factors - metabolism | Vascular Endothelial Growth Factor A - metabolism | Hypertension, Pulmonary - therapy | Idiopathic Pulmonary Fibrosis - metabolism | Vascular Endothelial Growth Factor Receptor-2 - genetics | Pulmonary Artery - metabolism | Idiopathic Pulmonary Fibrosis - complications | Vascular Endothelial Growth Factor A - pharmacology | Transforming Growth Factor beta1 - pharmacology | Disease Models, Animal | Fibroblasts - metabolism | Serpins - genetics | Endothelial Cells - metabolism | Smad2 Protein - metabolism | Rats | Lung - physiopathology | Nitric Oxide Synthase Type III - genetics | Rats, Sprague-Dawley | Eye Proteins - metabolism | Models, Biological | Nerve Growth Factors - genetics | Fibroblasts - drug effects | Idiopathic Pulmonary Fibrosis - pathology | Bronchoalveolar Lavage Fluid - chemistry | Hypertension, Pulmonary - etiology | Serum Albumin - metabolism | Phosphorylation | Female | Lung - metabolism | Eye Proteins - genetics | Lung - pathology | Serpins - metabolism | Vascular Endothelial Growth Factor A - therapeutic use | Microvessels - drug effects | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Transforming Growth Factor beta1 - genetics | Animals | Endothelial Cells - cytology | Pulmonary Artery - pathology | Endothelial Cells - drug effects | Immunohistochemistry | Usage | Care and treatment | Genetic aspects | Research | Health aspects | Vascular endothelial growth factor | Pulmonary hypertension | Risk factors | Apoptosis | Index Medicus | Abridged Index Medicus
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