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1. Ocular immunology and inflammation
International Ocular Inflammation Society
Ocular immunology and inflammation, ISSN 0927-3948, 1993
Eye | Immunological aspects | Inflammation | Diseases
Journal
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2. Full Text The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation
by Franklin, Bernardo S and Bossaller, Lukas and De Nardo, Dominic and Ratter, Jacqueline M and Stutz, Andrea and Engels, Gudrun and Brenker, Christoph and Nordhoff, Mark and Mirandola, Sandra R and Al-Amoudi, Ashraf and Mangan, Matthew S and Zimmer, Sebastian and Monks, Brian G and Fricke, Martin and Schmidt, Reinhold E and Espevik, Terje and Jones, Bernadette and Jarnicki, Andrew G and Hansbro, Philip M and Busto, Patricia and Marshak-Rothstein, Ann and Hornemann, Simone and Aguzzi, Adriano and Kastenmüller, Wolfgang and Latz, Eicke
Nature immunology, ISSN 1529-2908, 2014, Volume 15, Issue 8, pp. 727 - 737
Life Sciences & Biomedicine | Immunology | Science & Technology | Pseudomonas aeruginosa - immunology | Cell Communication - immunology | Caspase Inhibitors - pharmacology | Cytoskeletal Proteins - genetics | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Caspase 1 - immunology | Signal Transduction - immunology | Amino Acid Chloromethyl Ketones - pharmacology | Antibodies - immunology | Lysosomes - pathology | Macrophages - immunology | Mice, Inbred C57BL | Autoimmune Diseases - immunology | Phagocytosis - immunology | Interleukin-1beta - immunology | Inflammation - immunology | Prions - chemistry | Mice, Knockout | Pseudomonas Infections - immunology | Carrier Proteins - genetics | Autoantibodies - immunology | Animals | Apoptosis - immunology | Apoptosis Regulatory Proteins | Cytoskeletal Proteins - immunology | Caspase 1 - genetics | CARD Signaling Adaptor Proteins | Inflammasomes - immunology | Mice | Mice, Inbred BALB C | Cell interaction | Interleukin-1 | Immune response | Genetic research | Genetic aspects | Research | Properties | Index Medicus
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3. Full Text A rush to judgment on Th17
by Steinman, Lawrence
The Journal of experimental medicine, ISSN 0022-1007, 07/2008, Volume 205, Issue 7, pp. 1517 - 1522
Immunology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Dendritic Cells - immunology | Humans | Central Nervous System - pathology | Encephalomyelitis, Autoimmune, Experimental - immunology | Interleukin-23 - genetics | Encephalomyelitis, Autoimmune, Experimental - genetics | Disease Susceptibility | Macrophages - pathology | Interleukin-17 - genetics | Interleukin-12 Subunit p35 - genetics | Interleukin-23 - immunology | Mice, Knockout | Models, Immunological | Up-Regulation - immunology | Uveitis - immunology | Mice | Uveitis - genetics | Proteins - antagonists & inhibitors | Eye - pathology | Chemokines, CXC - immunology | Interleukin-17 - immunology | Autoimmunity - genetics | Neutralization Tests | Adoptive Transfer | Paralysis - pathology | Th1 Cells - immunology | Central Nervous System - immunology | Eye - immunology | Nitric Oxide Synthase Type II - immunology | Female | Interferon-gamma - genetics | Macrophages - immunology | Neutrophils - pathology | Inflammation Mediators - immunology | Cell Line | Encephalomyelitis, Autoimmune, Experimental - pathology | Myelin Sheath - immunology | Myelin Sheath - pathology | Gene Expression Regulation - immunology | Uveitis - prevention & control | Mice, Inbred C57BL | Neutrophils - immunology | Paralysis - immunology | Up-Regulation - genetics | Proteins - immunology | Antibodies - pharmacology | Gene Expression Regulation - drug effects | Animals | Interleukin-12 Subunit p35 - immunology | Interleukin-17 - antagonists & inhibitors | Lymphocyte Activation - drug effects | Interferon-gamma - immunology | Antigens - immunology | Autoimmunity - drug effects | Uveitis - pathology | Index Medicus | Commentaries
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4. Full Text Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity
by Hara, Hideki and Tsuchiya, Kohsuke and Kawamura, Ikuo and Fang, Rendong and Hernandez-Cuellar, Eduardo and Shen, Yanna and Mizuguchi, Junichiro and Schweighoffer, Edina and Tybulewicz, Victor and Mitsuyama, Masao
Nature immunology, ISSN 1529-2908, 12/2013, Volume 14, Issue 12, pp. 1247 - 1255
Life Sciences & Biomedicine | Immunology | Science & Technology | Interleukin-18 - immunology | Inflammasomes - metabolism | Cytoskeletal Proteins - genetics | NLR Family, Pyrin Domain-Containing 3 Protein | Protein-Tyrosine Kinases - metabolism | Dendritic Cells - immunology | Humans | JNK Mitogen-Activated Protein Kinases - immunology | Caspase 1 - metabolism | Immunoblotting | Intracellular Signaling Peptides and Proteins - metabolism | RNA Interference | Bone Marrow Cells - immunology | Phosphorylation - immunology | JNK Mitogen-Activated Protein Kinases - genetics | Intracellular Signaling Peptides and Proteins - genetics | Syk Kinase | Carrier Proteins - immunology | DNA-Binding Proteins | Tyrosine - immunology | Mice, Knockout | Macrophages - metabolism | Tyrosine - metabolism | Lipopolysaccharides - pharmacology | Mice | Interleukin-18 - metabolism | Intracellular Signaling Peptides and Proteins - immunology | JNK Mitogen-Activated Protein Kinases - metabolism | Caspase 1 - immunology | Protein-Tyrosine Kinases - immunology | Protein-Tyrosine Kinases - genetics | HEK293 Cells | Cytoskeletal Proteins - metabolism | Female | Nuclear Proteins - genetics | Dendritic Cells - metabolism | Macrophages - immunology | Mice, Inbred C57BL | Cells, Cultured | Nuclear Proteins - metabolism | Nuclear Proteins - immunology | Inflammasomes - genetics | Carrier Proteins - genetics | Animals | Apoptosis Regulatory Proteins | Carrier Proteins - metabolism | Cytoskeletal Proteins - immunology | CARD Signaling Adaptor Proteins | Inflammasomes - immunology | Macrophages - drug effects | Nigericin - pharmacology | Bone Marrow Cells - metabolism | Tyrosine - genetics | Cellular signal transduction | Inflammation | Genetic aspects | Research | Properties | Phosphotransferases | Index Medicus
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5. Full Text Mannan-binding lectin-associated serine protease (MASP)-1 is crucial for lectin pathway activation in human serum whereas neither MASP-1 nor MASP-3 is required for alternative pathway function
by Degn, Søren E and Jensen, Lisbeth and Hansen, Annette G and Duman, Duygu and Tekin, Mustafa and Jensenius, Jens C and Thiel, Steffen
The Journal of immunology (1950), ISSN 0022-1767, 10/2012, Volume 189, Issue 8, pp. 3957 - 3969
Life Sciences & Biomedicine | Immunology | Science & Technology | Craniofacial Abnormalities - immunology | Transcriptional Activation - genetics | Complement Pathway, Mannose-Binding Lectin - immunology | Blepharoptosis - genetics | Eye Abnormalities - enzymology | Mannose-Binding Protein-Associated Serine Proteases - physiology | Eye Abnormalities - immunology | Humans | Heart Defects, Congenital - immunology | Craniosynostoses - enzymology | Blepharoptosis - immunology | Developmental Disabilities - genetics | Transcriptional Activation - immunology | Strabismus - genetics | Abdominal Muscles - abnormalities | Abnormalities, Multiple - immunology | Heart Defects, Congenital - genetics | Developmental Disabilities - enzymology | Blepharoptosis - enzymology | Heart Defects, Congenital - enzymology | Mannose-Binding Protein-Associated Serine Proteases - genetics | Complement Pathway, Alternative - genetics | Abnormalities, Multiple - genetics | Craniofacial Abnormalities - genetics | Strabismus - enzymology | Abdominal Muscles - immunology | Craniosynostoses - genetics | Complement Pathway, Mannose-Binding Lectin - genetics | Cryptorchidism - enzymology | Abdominal Muscles - enzymology | Hip Dislocation, Congenital - genetics | Codon, Nonsense | Eye Abnormalities - genetics | Animals | Craniofacial Abnormalities - enzymology | Craniosynostoses - immunology | Cryptorchidism - immunology | Hip Dislocation, Congenital - immunology | Complement Pathway, Alternative - immunology | Strabismus - immunology | Abnormalities, Multiple - enzymology | Developmental Disabilities - immunology | Hip Dislocation, Congenital - enzymology | Cryptorchidism - genetics | Index Medicus | Abridged Index Medicus
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6. Full Text Neutrophil IL-1β processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux
by Karmakar, Mausita and Katsnelson, Michael and Malak, Hesham A and Greene, Neil G and Howell, Scott J and Hise, Amy G and Camilli, Andrew and Kadioglu, Aras and Dubyak, George R and Pearlman, Eric
The Journal of immunology (1950), ISSN 0022-1767, 02/2015, Volume 194, Issue 4, pp. 1763 - 1775
Life Sciences & Biomedicine | Immunology | Science & Technology | Pneumococcal Infections | Potassium - metabolism | Eye Infections, Bacterial - immunology | Keratitis - immunology | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Caspase 1 - metabolism | Caspase 1 - immunology | Enzyme Activation - immunology | Signal Transduction - immunology | Flow Cytometry | Interleukin-1beta - metabolism | Bacterial Proteins - immunology | Eye Infections, Bacterial - metabolism | Neutrophils - metabolism | Carrier Proteins - immunology | Disease Models, Animal | Apoptosis Regulatory Proteins - immunology | Enzyme-Linked Immunosorbent Assay | Mice, Inbred C57BL | Neutrophils - immunology | Interleukin-1beta - immunology | Blotting, Western | Mice, Knockout | Spectrophotometry, Atomic | Animals | CARD Signaling Adaptor Proteins | Inflammasomes - immunology | Fluorescent Antibody Technique | Keratitis - metabolism | Mice | Streptolysins - immunology | Index Medicus | Abridged Index Medicus
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7. Full Text An Ocular Commensal Protects against Corneal Infection by Driving an Interleukin-17 Response from Mucosal γδ T Cells
by St. Leger, Anthony J and Desai, Jigar V and Drummond, Rebecca A and Kugadas, Abirami and Almaghrabi, Fatimah and Silver, Phyllis and Raychaudhuri, Kumarkrishna and Gadjeva, Mihaela and Iwakura, Yoichiro and Lionakis, Michail S and Caspi, Rachel R
Immunity (Cambridge, Mass.), ISSN 1074-7613, 07/2017, Volume 47, Issue 1, pp. 148 - 158.e5
ocular surface disease | γδ T cells | IL-17 | host defense | ocular commensal bacteria | microbiome | mucosal immunity | Pseudomonas aeruginosa - immunology | Humans | Cornea - immunology | Immunity, Mucosal | Corynebacterium - immunology | Receptors, Antigen, T-Cell, gamma-delta - genetics | Candidiasis - microbiology | Corynebacterium Infections - microbiology | Eye Infections - microbiology | Neutrophil Infiltration | Corynebacterium Infections - immunology | Eye Infections - immunology | Neutrophils - microbiology | Candidiasis - immunology | Disease Models, Animal | Cornea - microbiology | Microbiota - immunology | Receptors, Antigen, T-Cell, gamma-delta - metabolism | Mice, Inbred C57BL | Neutrophils - immunology | Interleukin-17 - genetics | Tears - immunology | Candida albicans - immunology | Pseudomonas Infections - microbiology | Mice, Knockout | Pseudomonas Infections - immunology | Host-Pathogen Interactions | Interleukin-17 - metabolism | Animals | T-Lymphocytes - immunology | Mice | Cornea | Commensals | Disease | Mucosa | Interleukin | Homeostasis | Infections | Lymphocytes T | Nasopharynx | Immunity | Recruitment | Eye | Immunology | Lymphocytes | Intestine | Rodents | Bacteria | Immune system | Cytokines | Neutrophils | Vagina | Antimicrobial agents | Interleukin 17 | Studies | Oral cavity | Antibiotics | Flora | Tears | Index Medicus
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8. Full Text Pre-metastatic cancer exosomes induce immune surveillance by patrolling monocytes at the metastatic niche
by Plebanek, Michael P and Angeloni, Nicholas L and Vinokour, Elena and Li, Jia and Henkin, Anna and Martinez-Marin, Dalia and Filleur, Stephanie and Bhowmick, Reshma and Henkin, Jack and Miller, Stephen D and Ifergan, Igal and Lee, Yesung and Osman, Iman and Thaxton, C. Shad and Volpert, Olga V
Nature communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 1319 - 12
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Eye Proteins - immunology | Immunologic Surveillance | Humans | Lung Neoplasms - pathology | Monocytes - immunology | Melanoma, Experimental - immunology | Lung Neoplasms - secondary | Melanoma, Experimental - secondary | Exosomes - immunology | Monocytes - pathology | Killer Cells, Natural - immunology | Female | Macrophages - immunology | Macrophages - pathology | Mice, Inbred C57BL | Phagocytosis - immunology | Melanoma, Experimental - pathology | Nerve Growth Factors - immunology | Immunity, Innate | Serpins - immunology | Tumor Microenvironment - immunology | Cell Differentiation - immunology | Lung Neoplasms - immunology | Animals | Mice, Nude | Mice | Killing | Immune response | Melanoma | Immune clearance | Immunosurveillance | Metastasis | Exosomes | Macrophages | Epithelium | Metastases | Recruitment | Monocytes | Bone cancer | Surveillance | Lungs | Patrols | Bone marrow | Microenvironments | Pigment epithelium-derived factor | Niches | Cancer | Tumors | Immune system | Index Medicus
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9. Full Text STING regulates intracellular DNA-mediated, type i interferon-dependent innate immunity
by Ishikawa, Hiroki and Ma, Zhe and Barber, Glen N
Nature (London), ISSN 0028-0836, 10/2009, Volume 461, Issue 7265, pp. 788 - 792
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Fundamental immunology | Miscellaneous | Biological and medical sciences | Immunobiology | Regulatory factors and their cellular receptors | Analysis of the immune response. Humoral and cellular immunity | DNA, Bacterial - metabolism | Vesicular Transport Proteins - metabolism | Vaccines, DNA - immunology | Endoplasmic Reticulum - metabolism | DNA, Bacterial - immunology | Antigen-Presenting Cells - microbiology | Listeria monocytogenes - immunology | Interferon Type I - immunology | Interferon Type I - biosynthesis | Membrane Proteins - deficiency | Cytoplasmic Vesicles - metabolism | Plasmids - genetics | Herpesvirus 1, Human - immunology | Membrane Proteins - metabolism | Fibroblasts - microbiology | Protein-Serine-Threonine Kinases - metabolism | Fibroblasts - metabolism | Fibroblasts - virology | T-Lymphocytes, Cytotoxic - immunology | Antigen-Presenting Cells - metabolism | Intracellular Space - immunology | Membrane Proteins - genetics | Plasmids - immunology | DNA, Viral - metabolism | Antigen-Presenting Cells - immunology | Antigen-Presenting Cells - virology | Mice, Knockout | Protein Transport | DNA, Viral - immunology | Immunity, Innate - immunology | Animals | Intracellular Space - metabolism | Listeria monocytogenes - genetics | Fibroblasts - immunology | Herpesvirus 1, Human - genetics | Mice | Herpesvirus 1, Human - pathogenicity | Physiological aspects | Genetic aspects | Interferon | Immunity | Proteins | Viruses | Immunization | E coli | Research & development--R&D | Cells | Index Medicus
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