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Gastroenterology (New York, N.Y. 1943), ISSN 0016-5085, 2009, Volume 137, Issue 6, pp. 2052 - 2062
Background & Aims The winged helix transcription factors Foxa1 and Foxa2 are expressed in all epithelia of the gastrointestinal tract from its embryonic origin... 
Gastroenterology and Hepatology | RESPONSE ELEMENT | GLUCOSE-HOMEOSTASIS | GLUCAGON-LIKE PEPTIDE-1 | PROGLUCAGON GENE-TRANSCRIPTION | IN-VIVO | INSULIN-SECRETION | PANCREATIC BETA-CELLS | GASTROENTEROLOGY & HEPATOLOGY | ISLET CELLS | EXPRESSION | ENDOCRINE-CELLS | Immunohistochemistry | Hepatocyte Nuclear Factor 3-beta - genetics | Intestine, Small - pathology | Peptide YY - metabolism | Homeodomain Proteins - metabolism | Male | RNA, Messenger - metabolism | Cell Differentiation | Enteroendocrine Cells - metabolism | Proglucagon - metabolism | Somatostatin - metabolism | Repressor Proteins - metabolism | Hepatocyte Nuclear Factor 3-beta - metabolism | Mucin-2 - metabolism | Enteroendocrine Cells - pathology | Somatostatin-Secreting Cells - pathology | Glucagon-Like Peptide 1 - metabolism | Glucagon-Like Peptide 2 - metabolism | Hepatocyte Nuclear Factor 3-alpha - deficiency | Hepatocyte Nuclear Factor 3-alpha - genetics | PAX6 Transcription Factor | Goblet Cells - metabolism | Hepatocyte Nuclear Factor 3-alpha - metabolism | Mice, Knockout | Mucin-5B - metabolism | Animals | Eye Proteins - metabolism | Mucin 5AC - metabolism | LIM-Homeodomain Proteins | Mice | Transcription Factors | Goblet Cells - pathology | Intestine, Small - metabolism | Somatostatin-Secreting Cells - metabolism | Hepatocyte Nuclear Factor 3-beta - deficiency | Paired Box Transcription Factors - metabolism | Chromatin | Messenger RNA | DNA binding proteins | Cholecystokinin | Peptides | Mucins
Journal Article
Nature communications, ISSN 2041-1723, 2018, Volume 9, Issue 1, pp. 1864 - 11
Central corneal thickness (CCT) is a highly heritable trait associated with complex eye diseases such as keratoconus and glaucoma. We perform a genome-wide... 
DECORIN | CHROMATIN STATES | POLYMORPHISMS | RISK-FACTOR | MULTIDISCIPLINARY SCIENCES | MOUSE | GENE-EXPRESSION | MUTATIONS | HERITABILITY | LUMICAN | KERATOCONUS | Lumican - metabolism | Glaucoma, Open-Angle - genetics | Humans | Corneal Diseases - metabolism | Corneal Dystrophies, Hereditary - ethnology | Corneal Diseases - genetics | Ehlers-Danlos Syndrome - genetics | Corneal Dystrophies, Hereditary - pathology | Loeys-Dietz Syndrome - metabolism | Mendelian Randomization Analysis | Fibrillin-1 - metabolism | Cornea - pathology | Keratoconus - pathology | Corneal Diseases - pathology | Decorin - genetics | Gene Expression | Eye Diseases, Hereditary - pathology | Lumican - genetics | ADAMTS Proteins - metabolism | Proteoglycans - metabolism | Ehlers-Danlos Syndrome - ethnology | European Continental Ancestry Group | Myopia - pathology | Cornea - metabolism | Myopia - ethnology | Loeys-Dietz Syndrome - pathology | Corneal Diseases - ethnology | Marfan Syndrome - metabolism | Marfan Syndrome - pathology | Cornea - abnormalities | Quantitative Trait Loci | Proteoglycans - genetics | ADAMTS Proteins - genetics | Transforming Growth Factor beta2 - metabolism | Corneal Dystrophies, Hereditary - genetics | Glaucoma, Open-Angle - pathology | Keratoconus - metabolism | Loeys-Dietz Syndrome - ethnology | Glaucoma, Open-Angle - ethnology | Myopia - metabolism | Ehlers-Danlos Syndrome - pathology | Marfan Syndrome - ethnology | Keratoconus - genetics | Glaucoma, Open-Angle - metabolism | Fibrillin-1 - genetics | Eye Diseases, Hereditary - ethnology | Genome-Wide Association Study | Quantitative Trait, Heritable | Corneal Dystrophies, Hereditary - metabolism | Marfan Syndrome - genetics | Eye Diseases, Hereditary - genetics | Myopia - genetics | Asian Continental Ancestry Group | Keratoconus - ethnology | Ehlers-Danlos Syndrome - metabolism | Loeys-Dietz Syndrome - genetics | Polymorphism, Single Nucleotide | Transforming Growth Factor beta2 - genetics | Genome, Human | Decorin - metabolism | Eye Diseases, Hereditary - metabolism | Glaucoma | Cornea | Genes | Myopia | Association analysis | Genomes | Gene expression | Tissues | Connective tissues | Keratoconus | Collagen | Eye diseases | Extracellular matrix
Journal Article
Current biology, ISSN 0960-9822, 2010, Volume 20, Issue 7, pp. 573 - 581
Journal Article
Clinical & Experimental Ophthalmology, ISSN 1442-6404, 01/2006, Volume 34, Issue 1, pp. 64 - 73
Journal Article
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2011, Volume 332, Issue 6027, pp. 354 - 358
Cytonemes are types of filopodia in the Drosophila wing imaginal disc that are proposed to serve as conduits in which morphogen signaling proteins move between... 
Shock heating | Larvae | Receptors | Heat | Image resolution | Signaling proteins | Drosophila | Imaging | REPORTS | Instars | Cell separation | EYE | INHIBITION | PATTERN | SPITZ | DISC | TRIGGERS | MULTIDISCIPLINARY SCIENCES | EGF RECEPTOR | Wings, Animal - cytology | Pseudopodia - ultrastructure | Protein-Tyrosine Kinases - metabolism | Wings, Animal - ultrastructure | Hedgehog Proteins - metabolism | Trachea - metabolism | Drosophila Proteins - metabolism | Recombinant Fusion Proteins - metabolism | Fibroblast Growth Factors - metabolism | Wings, Animal - growth & development | Membrane Proteins - metabolism | Compound Eye, Arthropod - growth & development | Protein-Serine-Threonine Kinases - metabolism | Compound Eye, Arthropod - metabolism | Trachea - growth & development | Signal Transduction | Trachea - cytology | Protein-Serine-Threonine Kinases - genetics | Receptors, Cell Surface - metabolism | Compound Eye, Arthropod - cytology | Drosophila - cytology | Epidermal Growth Factor - metabolism | Drosophila - ultrastructure | Heat-Shock Response | Animals | Larva | Pseudopodia - metabolism | Receptors, Fibroblast Growth Factor - metabolism | Ligands | Drosophila - growth & development | Drosophila - metabolism | Drosophila Proteins - genetics | Receptors, Cell Surface - genetics | Genetic aspects | Proteins | Signal transduction | Insects | Cellular biology | Developmental biology
Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 2012, Volume 287, Issue 7, pp. 5059 - 5069
Compromised clearance of all-trans-retinal (atRAL), a component of the retinoid cycle, increases the susceptibility of mouse retina to acute light-induced... 
VISUAL CYCLE | OXIDATIVE STRESS | ACTIVATED PROTEIN-KINASE | 5-HT1A RECEPTORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | PHOSPHOLIPASE-C | IN-VIVO | RECESSIVE RETINITIS-PIGMENTOSA | GENE ABCR | BINDING-PROPERTIES | NEUTROPHIL NADPH-OXIDASE | Reactive Oxygen Species - metabolism | Receptor, Serotonin, 5-HT2A - genetics | Calcium - metabolism | Humans | NADPH Oxidases - metabolism | Corneal Dystrophies, Hereditary - genetics | Type C Phospholipases - metabolism | Retinaldehyde - metabolism | Alcohol Oxidoreductases - genetics | ATP-Binding Cassette Transporters - genetics | Corneal Dystrophies, Hereditary - pathology | ATP-Binding Cassette Transporters - metabolism | NADPH Oxidases - genetics | Signal Transduction | Light - adverse effects | Receptor, Muscarinic M3 - metabolism | Alcohol Oxidoreductases - metabolism | Corneal Dystrophies, Hereditary - metabolism | Receptor, Muscarinic M3 - genetics | Serotonin 5-HT2 Receptor Antagonists - pharmacology | Mice, Knockout | Macular Degeneration - metabolism | Animals | Macular Degeneration - genetics | Type C Phospholipases - genetics | Mice | Inositol 1,4,5-Trisphosphate - genetics | Photoreceptor Cells, Vertebrate - metabolism | Receptor, Serotonin, 5-HT2A - metabolism | Inositol 1,4,5-Trisphosphate - metabolism | Photoreceptor Cells, Vertebrate - pathology | Macular Degeneration - pathology | Molecular Bases of Disease | Vitamin A | Retinal metabolism | Vision | Reactive oxygen species (ROS) | Retinoid
Journal Article
Fluids and barriers of the CNS, ISSN 2045-8118, 2018, Volume 15, Issue 1, pp. 24 - 17
Breakdown of the blood-brain barrier (BBB) or inner blood-retinal barrier (BRB), induced by pathologically elevated levels of vascular endothelial growth... 
Plasmalemma vesicle-associated protein | Blood-brain barrier | Blood-retinal barrier | Cerebral edema | Diabetic macular edema | INDUCED RETINOPATHY | VASCULAR-PERMEABILITY | TRANSCELLULAR TRANSPORT | NEUROSCIENCES | DIFFERENTIATED MICRODOMAINS | MEDIATED TRANSCYTOSIS | FENESTRATED ENDOTHELIA | ANTIGEN PAL-E | LUMINAL SURFACE | CAPILLARY ENDOTHELIUM | ENDOTHELIAL GROWTH-FACTOR | Eye - metabolism | Brain Edema - metabolism | Capillary Permeability | Brain Edema - pathology | Diabetes Complications - metabolism | Humans | Macular Edema - pathology | Blood-Retinal Barrier - pathology | Macular Edema - metabolism | Blood-Brain Barrier - metabolism | Blood-Retinal Barrier - metabolism | Brain - metabolism | Blood-Brain Barrier - pathology | Animals | Carrier Proteins - metabolism | Macular Edema - complications | Membrane Proteins - metabolism | Diabetes Complications - pathology | Diabetic retinopathy | Brain | Nervous system diseases | Neurons | Mortality | Cell membranes | Permeability | Endothelium | Stroke (Disease) | Proteins | Health aspects | Vascular endothelial growth factor | Corticoids | Neuroprotection | Retinopathy | Brain cancer | Central nervous system | Retina | Angiogenesis | Ischemia | Protein transport | Edema | Stroke | Wound healing | Caveolae | Therapeutic applications | Diabetes mellitus | Morbidity | Endothelial cells | Plasma membranes | Diabetes | Cancer | Structure-function relationships | Blood–retinal barrier | Blood–brain barrier
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2004, Volume 279, Issue 47, pp. 48647 - 48653
Journal Article