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Nature Genetics, ISSN 1061-4036, 09/2009, Volume 41, Issue 9, pp. 1027 - 1031
The primary cilium is an antenna-like structure that protrudes from the cell surface of quiescent/differentiated cells and participates in extracellular signal... 
NETWORK | INOSITOL-POLYPHOSPHATE 5-PHOSPHATASE | POLYCYSTIC KIDNEY-DISEASE | BIOLOGY | GENETICS & HEREDITY | DISORDERS | PROTEINS | FIBROBLASTS | Humans | Fluorescent Dyes - metabolism | Culture Media, Serum-Free | Male | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Fibroblasts - ultrastructure | Obesity - genetics | Embryo, Mammalian - metabolism | Intellectual Disability - genetics | Indoles - metabolism | Tubulin - metabolism | Cell Nucleus - metabolism | Transfection | Mice, Mutant Strains | Cilia - ultrastructure | Bardet-Biedl Syndrome - genetics | Chromones - pharmacology | Microsatellite Repeats | Fibroblasts - metabolism | Genetic Linkage | Cell Line | Green Fluorescent Proteins - metabolism | Phosphoric Monoester Hydrolases - genetics | Cilia - pathology | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Fluorescent Antibody Technique, Direct | Retinal Degeneration - genetics | Cells, Cultured | Enzyme Inhibitors - pharmacology | Morpholines - pharmacology | Mice, Transgenic | Genetic Markers | Cilia - metabolism | Cilia - genetics | Pigment Epithelium of Eye - metabolism | Animals | Embryo, Mammalian - cytology | Signal Transduction - physiology | Fibroblasts - cytology | Mice | Polymorphism, Single Nucleotide | Mutation | Pigment Epithelium of Eye - cytology | Penis - abnormalities | Gene mutations | Genetic aspects | Cellular signal transduction | Research | Health aspects | Risk factors | Brain diseases | Proteins | Tissue | Scanning electron microscopy | Transmission electron microscopy | Cysts | Rodents | Cell division | Index Medicus
Journal Article
Laboratory Investigation, ISSN 0023-6837, 05/2012, Volume 92, Issue 5, pp. 713 - 723
Non-alcoholic steatohepatitis (NASH) is typically associated with pro-apoptotic caspase activation. A potential role for pro-inflammatory caspases remains... 
Inflammasome | Inflammation | Caspases | Non-alcoholic fatty liver disease | Non-alcoholic steatohepatitis | Fibrosis | MEDICINE, RESEARCH & EXPERIMENTAL | POPULATION | APOPTOSIS | non-alcoholic fatty liver disease | MICE DEFICIENT | FATTY LIVER-DISEASE | INJURY | NONALCOHOLIC STEATOHEPATITIS | MODEL | PATHOLOGY | inflammation | inflammasome | fibrosis | caspases | HEPATIC STEATOSIS | non-alcoholic steatohepatitis | Tumor Necrosis Factor-alpha - metabolism | Liver - pathology | Clodronic Acid - pharmacology | Fatty Liver - pathology | Actins - metabolism | Caspase 3 - metabolism | Hepatic Stellate Cells - metabolism | Caspase 1 - metabolism | Choline Deficiency - complications | Hepatocytes - pathology | Hepatocytes - metabolism | Fatty Liver - chemically induced | LIM Domain Proteins - metabolism | Liver Cirrhosis - chemically induced | Inflammation - metabolism | Caspase 3 - blood | Interleukin-1beta - metabolism | Choline Deficiency - metabolism | Liver Cirrhosis - metabolism | Muscle Proteins - metabolism | Antigens, Differentiation - metabolism | Kupffer Cells - metabolism | Hepatic Stellate Cells - pathology | Methionine - deficiency | Collagen Type I - metabolism | Fatty Liver - metabolism | Liver - metabolism | Mice, Inbred C57BL | Nuclear Proteins - metabolism | Choline Deficiency - pathology | Kupffer Cells - drug effects | Mice, Knockout | Animals | Caspase 1 - genetics | Caspase 1 - deficiency | Liver Cirrhosis - pathology | Mice | Transforming Growth Factor beta - metabolism | Index Medicus | Nonalcoholic fatty liver disease (NAFLD) | nonalcoholic steatohepatitis (NASH)
Journal Article
STEM CELLS, ISSN 1066-5099, 05/2004, Volume 22, Issue 3, pp. 355 - 366
This study evaluated proposed molecular markers related to stem cell (SC) properties with the intention of characterizing a putative SC phenotype in human... 
Cornea | Limbus | Epithelium | Stem cell phenotype | Stem cells | LOCATION | stem cells | LOCALIZATION | TRANSPORTER | cornea | CORNEAL EPITHELIUM | stem cell phenotype | P53 HOMOLOG | P63 | CELL BIOLOGY | INVOLUCRIN SYNTHESIS | ONCOLOGY | TRANSIT AMPLIFYING CELLS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | limbus | epithelium | HEMATOLOGY | HUMAN OCULAR SURFACE | EXPRESSION | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Nestin | Bacterial Capsules | Cadherins - metabolism | Humans | Phosphopyruvate Hydratase - metabolism | Epithelium - ultrastructure | Stem Cells - cytology | Neoplasm Proteins - metabolism | Stem Cells - metabolism | Integrins - metabolism | Antigens, CD - metabolism | DNA-Binding Proteins - metabolism | Limbus Corneae - metabolism | ATP-Binding Cassette Transporters - metabolism | Biomarkers, Tumor - metabolism | Membrane Proteins - metabolism | Microscopy, Electron, Transmission | Tumor Suppressor Proteins - metabolism | Connexin 43 - metabolism | Epithelium - metabolism | Limbus Corneae - ultrastructure | Genes, erbB-1 - genetics | Polysaccharides, Bacterial - metabolism | Epithelium, Corneal - ultrastructure | Receptors, Transferrin - metabolism | Stem Cells - ultrastructure | Nerve Tissue Proteins - metabolism | Microscopy, Confocal | Epithelium, Corneal - metabolism | Intermediate Filament Proteins - metabolism | Index Medicus
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 02/2014, Volume 67, pp. 221 - 234
Caffeine administered to preterm infants has been shown to reduce rates of cerebral palsy and cognitive delay, compared to placebo. We investigated the... 
Methylxanthine | Oxidative stress | Postnatal neurogenesis | Developmental brain | Free radicals | Hyperoxia | Preterm infants | PROGENITOR CELLS | A(2A) RECEPTOR ANTAGONISTS | FUNCTIONAL IMPLICATIONS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ADULT HIPPOCAMPAL NEUROGENESIS | TNF-ALPHA PRODUCTION | NEURAL STEM-CELLS | INTENSIVE-CARE-UNIT | ENDOCRINOLOGY & METABOLISM | DENTATE GYRUS | EXPRESSION | Cell Proliferation | Homeodomain Proteins - metabolism | Cerebral Cortex - pathology | Ki-67 Antigen - metabolism | SOXB1 Transcription Factors - metabolism | Dentate Gyrus - drug effects | SOXB1 Transcription Factors - genetics | Hyperoxia - metabolism | Caffeine - pharmacology | Neurons - metabolism | Cerebral Cortex - drug effects | Repressor Proteins - metabolism | Animals, Newborn | Biomarkers - metabolism | Gene Expression | Tumor Suppressor Proteins - metabolism | Dentate Gyrus - metabolism | Rats | Repressor Proteins - genetics | Neuropeptides - metabolism | T-Box Domain Proteins - metabolism | Hyperoxia - pathology | Eye Proteins - metabolism | Ki-67 Antigen - genetics | Dentate Gyrus - pathology | Paired Box Transcription Factors - genetics | Neurons - pathology | Microtubule-Associated Proteins - genetics | Rats, Wistar | Antigens, Nuclear - metabolism | Microtubule-Associated Proteins - metabolism | Gray Matter - drug effects | Cerebral Cortex - metabolism | Gray Matter - metabolism | Tumor Suppressor Proteins - genetics | Nestin - genetics | Eye Proteins - genetics | Neuropeptides - genetics | Neurons - drug effects | PAX6 Transcription Factor | Hyperoxia - prevention & control | Nerve Tissue Proteins - genetics | T-Box Domain Proteins - genetics | Homeodomain Proteins - genetics | Nerve Tissue Proteins - metabolism | Nestin - metabolism | Animals | Antigens, Nuclear - genetics | Gray Matter - pathology | Paired Box Transcription Factors - metabolism | Antioxidants | Neurons | Analysis | Caffeine | Index Medicus
Journal Article
Journal of Cell Science, ISSN 0021-9533, 06/2009, Volume 122, Issue 11, pp. 1834 - 1841
Lipid droplets (LDs) are cytoplasmic organelles that store neutral lipids for use as an energy supply in times of nutrient deprivation and for membrane... 
Lipid homeostasis | ATGL | Lipid droplet | ADIPOSE TRIGLYCERIDE LIPASE | CELLS | GOLGI | CELL BIOLOGY | FAT STORAGE | LIPOLYSIS | LIPODYSTROPHY | ENDOPLASMIC-RETICULUM | BREFELDIN-A | DIFFERENTIATION-RELATED PROTEIN | RNA, Small Interfering - genetics | Fluorescence Recovery After Photobleaching | Humans | Adaptor Proteins, Vesicular Transport - genetics | Endoplasmic Reticulum - metabolism | Lipids | Protein Transport - physiology | Intracellular Signaling Peptides and Proteins - metabolism | Pregnancy Proteins - metabolism | Coat Protein Complex I - metabolism | Adaptor Proteins, Vesicular Transport - metabolism | Recombinant Fusion Proteins - metabolism | Endoplasmic Reticulum - ultrastructure | DNA-Binding Proteins - metabolism | Organelles - ultrastructure | Guanine Nucleotide Exchange Factors - metabolism | ADP-Ribosylation Factor 1 - metabolism | Membrane Proteins - metabolism | ADP-Ribosylation Factor 1 - genetics | Golgi Apparatus - ultrastructure | Vesicular Transport Proteins | Guanine Nucleotide Exchange Factors - genetics | Lipase - metabolism | Protein Synthesis Inhibitors - metabolism | Brefeldin A - metabolism | Coatomer Protein - metabolism | Recombinant Fusion Proteins - genetics | Golgi Apparatus - metabolism | HeLa Cells | Organelles - metabolism | Perilipin-3 | Perilipin-2 | Lipase - genetics | RNA, Small Interfering - metabolism | Index Medicus
Journal Article
Nature Medicine, ISSN 1078-8956, 04/2016, Volume 22, Issue 4, pp. 439 - 445
Journal Article
Gastroenterology, ISSN 0016-5085, 2009, Volume 137, Issue 6, pp. 2052 - 2062
Background & Aims The winged helix transcription factors Foxa1 and Foxa2 are expressed in all epithelia of the gastrointestinal tract from its embryonic origin... 
Gastroenterology and Hepatology | RESPONSE ELEMENT | GLUCOSE-HOMEOSTASIS | GLUCAGON-LIKE PEPTIDE-1 | PROGLUCAGON GENE-TRANSCRIPTION | IN-VIVO | INSULIN-SECRETION | PANCREATIC BETA-CELLS | GASTROENTEROLOGY & HEPATOLOGY | ISLET CELLS | EXPRESSION | ENDOCRINE-CELLS | Immunohistochemistry | Hepatocyte Nuclear Factor 3-beta - genetics | Intestine, Small - pathology | Peptide YY - metabolism | Homeodomain Proteins - metabolism | Male | RNA, Messenger - metabolism | Cell Differentiation | Enteroendocrine Cells - metabolism | Proglucagon - metabolism | Somatostatin - metabolism | Repressor Proteins - metabolism | Hepatocyte Nuclear Factor 3-beta - metabolism | Mucin-2 - metabolism | Enteroendocrine Cells - pathology | Somatostatin-Secreting Cells - pathology | Glucagon-Like Peptide 1 - metabolism | Glucagon-Like Peptide 2 - metabolism | Hepatocyte Nuclear Factor 3-alpha - deficiency | Hepatocyte Nuclear Factor 3-alpha - genetics | PAX6 Transcription Factor | Goblet Cells - metabolism | Hepatocyte Nuclear Factor 3-alpha - metabolism | Mice, Knockout | Mucin-5B - metabolism | Animals | Eye Proteins - metabolism | Mucin 5AC - metabolism | LIM-Homeodomain Proteins | Mice | Transcription Factors | Goblet Cells - pathology | Intestine, Small - metabolism | Somatostatin-Secreting Cells - metabolism | Hepatocyte Nuclear Factor 3-beta - deficiency | Paired Box Transcription Factors - metabolism | Chromatin | Messenger RNA | DNA binding proteins | Cholecystokinin | Peptides | Mucins | Index Medicus | Abridged Index Medicus
Journal Article
Cell, ISSN 0092-8674, 2007, Volume 128, Issue 5, pp. 961 - 975
Anaplastic lymphoma kinase (Alk) has been proposed to regulate neuronal development based on its expression pattern in vertebrates and invertebrates; however,... 
ANAPLASTIC LYMPHOMA KINASE | SYNAPTIC SPECIFICITY | NERVOUS-SYSTEM | NEURONAL DEVELOPMENT | PHOTORECEPTOR AXONS | BIOCHEMISTRY & MOLECULAR BIOLOGY | NON-HODGKINS-LYMPHOMA | VISUAL-SYSTEM | GLIAL-CELLS | ROLLING PEBBLES | LAYER-SELECTION | CELL BIOLOGY | Retina - metabolism | Retina - growth & development | Cadherins - metabolism | Protein-Tyrosine Kinases - metabolism | Male | Optic Lobe, Nonmammalian - growth & development | Drosophila Proteins - metabolism | Drosophila melanogaster - metabolism | Protein-Tyrosine Kinases - genetics | Anaplastic Lymphoma Kinase | Retina - cytology | Larva - growth & development | Muscle Proteins - metabolism | Eye - innervation | Female | Cell Adhesion Molecules, Neuronal - metabolism | Membrane Proteins - metabolism | Photoreceptor Cells, Invertebrate - cytology | Pupa - growth & development | Signal Transduction | Animals, Genetically Modified | Axons - metabolism | Eye - growth & development | Receptor Protein-Tyrosine Kinases | Animals | Eye Proteins - metabolism | Drosophila melanogaster - growth & development | Photoreceptor Cells, Invertebrate - metabolism | Drosophila | Index Medicus | Muscle Proteins/metabolism | Photoreceptors; Invertebrate/cytology/metabolism | Axons/metabolism | Larva/growth & development | Drosophila Proteins/metabolism | Animals; Genetically Modified | Optic Lobe/growth & development | Protein-Tyrosine Kinases/genetics/metabolism | Pupa/growth & development | Cell Adhesion Molecules; Neuronal/metabolism | Membrane Proteins/metabolism | Cadherins/metabolism | Drosophila melanogaster/growth & development/metabolism | Eye Proteins/metabolism | Eye/growth & development/innervation | Retina/cytology/growth & development/metabolism
Journal Article
Current Biology, ISSN 0960-9822, 04/2010, Volume 20, Issue 7, pp. 573 - 581
Journal Article