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Nature, ISSN 0028-0836, 2014, Volume 506, Issue 7488, pp. 371 - 375
Cervical cancer is responsible for 10-15% of cancer-related deaths in women worldwide(1,2). The aetiological role of infection with high-risk human papilloma... 
DOMAIN | CATALOG | FUSION | MULTIDISCIPLINARY SCIENCES | FRAMEWORK | HUMAN-PAPILLOMAVIRUS | SENSITIVE DETECTION | CANCER | EXPRESSION | SOMATIC MUTATIONS | DISCOVERY | F-Box-WD Repeat-Containing Protein 7 | Receptor, ErbB-2 - genetics | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - virology | Genomics | Humans | E1A-Associated p300 Protein - genetics | Core Binding Factor beta Subunit - genetics | Case-Control Studies | Papillomaviridae - genetics | Tumor Suppressor Protein p53 - genetics | DNA Mutational Analysis | Mitogen-Activated Protein Kinase 1 - genetics | Cell Cycle Proteins - genetics | Female | NF-E2-Related Factor 2 - genetics | Adenocarcinoma - genetics | Papillomaviridae - physiology | HLA-B Antigens - genetics | Gene Expression Regulation, Neoplastic - genetics | Proto-Oncogene Proteins c-ets | Virus Integration - genetics | Proto-Oncogene Proteins - genetics | DNA Copy Number Variations - genetics | Transcriptome - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Mutation - genetics | Uterine Cervical Neoplasms - genetics | Adenocarcinoma - virology | Genome, Human - genetics | Papillomavirus Infections - genetics | Exome - genetics | Uterine Cervical Neoplasms - virology | Ubiquitin-Protein Ligases - genetics | F-Box Proteins - genetics | Prevention | Gene mutations | Oncology, Experimental | Exome sequencing | Genetic aspects | Research | Cervical cancer | Cancer | Human papillomavirus | Mutation
Journal Article
NATURE, ISSN 0028-0836, 07/2009, Volume 460, Issue 7253, pp. 405 - U125
Journal Article
Nature Genetics, ISSN 1061-4036, 12/2012, Volume 44, Issue 12, pp. 1310 - 1315
Journal Article
Nature Communications, ISSN 2041-1723, 07/2015, Volume 6, Issue 1, p. 7557
Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma in childhood. Here we studied 60 RMSs using whole-exome/-transcriptome sequencing, copy number... 
WIDE DNA METHYLATION | AMPLIFICATION | PIK3CA GENE | EMBRYONAL RHABDOMYOSARCOMA | PATHWAY MUTATIONS | ADOLESCENTS | MULTIDISCIPLINARY SCIENCES | PTEN | ALVEOLAR RHABDOMYOSARCOMA | HUMAN CANCER | BREAST | Paired Box Transcription Factors - genetics | F-Box-WD Repeat-Containing Protein 7 | ras Proteins - genetics | Prognosis | Rhabdomyosarcoma, Embryonal - classification | Humans | Transcriptome | Child, Preschool | PAX7 Transcription Factor - genetics | Infant | Male | Rhabdomyosarcoma, Alveolar - classification | RNA, Messenger - metabolism | Proto-Oncogene Proteins c-akt - genetics | Tumor Suppressor Protein p53 - genetics | Exome | Rhabdomyosarcoma, Embryonal - genetics | Young Adult | Cell Cycle Proteins - genetics | Female | Receptor, Fibroblast Growth Factor, Type 4 - genetics | Child | Gene Expression Regulation, Neoplastic - genetics | PTEN Phosphohydrolase - genetics | PAX3 Transcription Factor | Rhabdomyosarcoma, Alveolar - genetics | Repressor Proteins - genetics | Proto-Oncogene Proteins - genetics | DNA Methylation - genetics | Forkhead Transcription Factors - genetics | beta Catenin - genetics | Epigenesis, Genetic - genetics | Adolescent | Rhabdomyosarcoma - classification | Forkhead Box Protein O1 | Rhabdomyosarcoma - genetics | Mutation | Ubiquitin-Protein Ligases - genetics | F-Box Proteins - genetics
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 05/2012, Volume 109, Issue 19, pp. E1192 - E1200
Plants must effectively defend against biotic and abiotic stresses to survive in nature. However, this defense is costly and is often accompanied by... 
Light response | Disease resistance | Plant growth | Plant defense | Plant immunity | plant growth | TRANSCRIPTION FACTORS | ARABIDOPSIS-THALIANA | CYTOCHROME-P450 MONOOXYGENASE | PROTEIN | MULTIDISCIPLINARY SCIENCES | RECEPTOR | RESPONSES | plant defense | disease resistance | GENE | light response | REPRESSOR | plant immunity | ALPHA-AMYLASE | RICE | Arabidopsis - growth & development | Oryza - metabolism | Seedlings - genetics | Arabidopsis Proteins - metabolism | DNA-Binding Proteins - metabolism | Proteolysis - drug effects | Oryza - growth & development | Basic Helix-Loop-Helix Transcription Factors - metabolism | Oryza - genetics | Plants - genetics | RNA Interference | Gibberellins - metabolism | Plant Proteins - metabolism | Repressor Proteins - metabolism | Arabidopsis Proteins - genetics | Basic Helix-Loop-Helix Transcription Factors - genetics | Plant Development | F-Box Proteins - metabolism | Repressor Proteins - genetics | Signal Transduction - genetics | Cyclopentanes - pharmacology | Seedlings - drug effects | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Arabidopsis - metabolism | Arabidopsis - genetics | Transcription Factors - metabolism | Oxylipins - metabolism | Plant Proteins - genetics | Two-Hybrid System Techniques | Gene Expression Regulation, Plant - drug effects | Plants - metabolism | Signal Transduction - drug effects | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - genetics | Oxylipins - pharmacology | Gibberellins - pharmacology | Protein Binding | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - metabolism | Cyclopentanes - metabolism | Signal Transduction - physiology | Mutation | Plant Growth Regulators - metabolism | F-Box Proteins - genetics | Plant Growth Regulators - pharmacology | Seedlings - metabolism | Biological Sciences | PNAS Plus
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 135, Issue 6, pp. 1476 - 1485.e7
Background Chronic rhinosinusitis (CRS) with nasal polyps (NPs) in Western populations is associated with TH 2 cytokine polarization. IL-25, an IL-17 family... 
Allergy and Immunology | sinusitis | allergy | animal models | IL-25 | Nasal polyp | SKIN BARRIER DYSFUNCTION | MAST-CELLS | CYTOKINE | INNATE LYMPHOID-CELLS | IMMUNOLOGY | ATOPIC-DERMATITIS | RESPONSES | INTERLEUKIN-17 FAMILY | INFLAMMATION | MOUSE MODEL | IN-VIVO | Eosinophil Cationic Protein - genetics | Eosinophils - drug effects | Humans | Middle Aged | Male | Receptors, Interleukin-17 - genetics | Eosinophils - immunology | Rhinitis - drug therapy | Eosinophil Cationic Protein - immunology | Transforming Growth Factor beta2 - immunology | Sinusitis - genetics | Gene Expression - immunology | Eosinophils - pathology | Disease Models, Animal | Nuclear Receptor Subfamily 1, Group F, Member 3 - immunology | Antibodies, Monoclonal - pharmacology | Neutrophils - drug effects | Interleukin-17 - genetics | Rhinitis - complications | Mice | Chronic Disease | Sinusitis - drug therapy | GATA3 Transcription Factor - genetics | Cell Adhesion Molecules - genetics | Gene Expression - drug effects | GATA3 Transcription Factor - immunology | Receptors, Interleukin-17 - immunology | Interleukin-17 - immunology | T-Box Domain Proteins - immunology | Cell Adhesion Molecules - immunology | Case-Control Studies | Sinusitis - complications | Transforming Growth Factor beta1 - immunology | Sinusitis - immunology | Nasal Polyps - genetics | Adult | Female | Nuclear Receptor Subfamily 1, Group F, Member 3 - genetics | Neutrophils - pathology | Nasal Polyps - immunology | Rhinitis - immunology | Neutrophils - immunology | Transforming Growth Factor beta1 - genetics | Nasal Polyps - drug therapy | T-Box Domain Proteins - genetics | Rhinitis - genetics | Animals | Nasal Polyps - complications | Interleukin-17 - antagonists & inhibitors | Transforming Growth Factor beta2 - genetics | Medical colleges | Nurse practitioners | Nasal polyps | Atopic dermatitis | Health aspects | Proteins | Immunoglobulins | Pulmonary fibrosis | Disease | Laboratories | Rodents | Surgery | Family medical history | Endoscopy | Quality of life
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2012, Volume 7, Issue 10, p. e46082
MicroRNA (miR)-155 is a critical player in both innate and adaptive immune responses. It can influence CD4(+) T cell lineage choice. To clarify the role of... 
PREVENTS DEVELOPMENT | SUPPRESSOR | ACTIVATION | MULTIDISCIPLINARY SCIENCES | STAT3 | T(H)17 | CD4(+) T-CELLS | RECEPTOR | ABSENCE | INDUCTION | EXPRESSION | GATA3 Transcription Factor - genetics | T-Lymphocytes, Regulatory - metabolism | Transforming Growth Factor beta1 - metabolism | STAT Transcription Factors - metabolism | Suppressor of Cytokine Signaling 1 Protein | Janus Kinases - metabolism | Interferon-gamma - metabolism | Cell Differentiation - genetics | Th17 Cells - metabolism | Base Sequence | T-Lymphocytes, Regulatory - cytology | Interleukin-10 - metabolism | Th17 Cells - cytology | Interferon-gamma - genetics | Interleukin-4 - genetics | GATA3 Transcription Factor - metabolism | Nuclear Receptor Subfamily 1, Group F, Member 3 - genetics | Signal Transduction | Interleukin-4 - metabolism | Gene Expression Regulation | Suppressor of Cytokine Signaling Proteins - genetics | Forkhead Transcription Factors - genetics | T-Box Domain Proteins - genetics | T-Box Domain Proteins - metabolism | Interleukin-17 - metabolism | Animals | Mice | MicroRNAs - genetics | Smad Proteins - metabolism | Physiological aspects | Genetic aspects | MicroRNA | Research | Cell differentiation | T cells | Smad5 protein | Smad protein | Transcription factors | Transcription | Laboratories | Interleukin | Differentiation (biology) | Helper cells | Science | Homology | Lymphocytes T | Inflammatory diseases | Signal transduction | Immunology | Transfection | Lymphocytes | Smad2 protein | Atherosclerosis | CD25 antigen | Janus kinase | Cardiology | Growth factors | Immune system | Function analysis | Lupus | Immune response | Cytokines | MiRNA | Cell lineage | T cell receptors | Gene expression | Ribonucleic acid--RNA | Suppressors | CD4 antigen | Signaling | MicroRNAs | Interleukin 10 | RNA | Ribonucleic acid
Journal Article
Immunity, ISSN 1074-7613, 08/2015, Volume 43, Issue 2, pp. 354 - 368
Type 2 innate lymphoid cells (ILC2s) promote anti-helminth responses and contribute to allergies. Here, we report that Bcl11b, previously considered a... 
INTESTINAL INFLAMMATION | DOUBLE-POSITIVE THYMOCYTES | ALLERGIC INFLAMMATION | ROR-GAMMA-T | COMMENSAL BACTERIA | REGULATORY CELLS | FACTOR GATA3 | NOTCH | SPECIFICATION | IMMUNOLOGY | LYMPHOCYTES | GATA3 Transcription Factor - genetics | Interleukin-1 Receptor-Like 1 Protein | Th2 Cells - immunology | Eosinophils - immunology | Cell Movement - genetics | Lymphocyte Subsets - immunology | DNA-Binding Proteins - metabolism | Enterobacteriaceae Infections - immunology | Lymphocytes - immunology | Tumor Suppressor Proteins - genetics | Cell Differentiation | GATA3 Transcription Factor - metabolism | Nuclear Receptor Subfamily 1, Group F, Member 3 - genetics | Repressor Proteins - metabolism | Tumor Suppressor Proteins - metabolism | Basic Helix-Loop-Helix Transcription Factors - genetics | Citrobacter rodentium - immunology | Gene Expression Regulation - genetics | Cells, Cultured | Neutrophils - immunology | Receptors, Aryl Hydrocarbon - genetics | Repressor Proteins - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Immunity, Innate | Mice, Inbred Strains | Receptors, Interleukin - genetics | Transcription Factors - metabolism | Cell Lineage | Animals | Mice | Allergens | Papain | T cells | Genomics | Cells | Confidence intervals | Transcription factors | Cytokines | Lymphocytes | Rodents | Genomes | Gene expression | Viral infections
Journal Article