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CHEMICAL REVIEWS, ISSN 0009-2665, 01/2016, Volume 116, Issue 2, pp. 719 - 766
Diverse radiochemistry is an essential component of nuclear medicine; this includes imaging techniques such as positron emission tomography (PET). As such, PET... 
CROSS-COUPLING REACTIONS | COPPER-MEDIATED FLUORINATION | F BOND FORMATION | F-18 ACETYL HYPOFLUORITE | HIGH-AFFINITY RADIOLIGAND | NICOTINIC ACETYLCHOLINE-RECEPTORS | ELECTRON-RICH ARENES | IN-VIVO EVALUATION | CHEMISTRY, MULTIDISCIPLINARY | HIGH-YIELD SYNTHESIS | NUCLEOPHILIC AROMATIC-SUBSTITUTION
Journal Article
Organic Letters, ISSN 1523-7060, 10/2016, Volume 18, Issue 20, pp. 5440 - 5443
A copper-mediated nucleophilic radiofluorination of aryl- and vinylstannanes with [18F]­KF is described. This method is fast, uses commercially available... 
STANNANES | POSITRON-EMISSION-TOMOGRAPHY | ELEMENTAL FLUORINE | CHEMISTRY, ORGANIC | OXIDATIVE FLUORINATION | ARYL-TIN BONDS | LATE-STAGE FLUORINATION | ACETYL HYPOFLUORITE | PET | F-18 | PARKINSONS-DISEASE | RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY | Letter
Journal Article
Journal of Fluorine Chemistry, ISSN 0022-1139, 01/2013, Volume 145, pp. 112 - 117
► We performed a reaction between 0.1% F2 and cresolsulfonphthalein in acidic media. ► We observed a specific fluorination into ortho positions to hydroxyl... 
Cresol Purple | Fluorine | Electrophilic fluorination | pH measurement | ELEMENTAL FLUORINE | IN-VIVO | CHEMISTRY, ORGANIC | ACETYL HYPOFLUORITE | F-18 | CHEMISTRY, INORGANIC & NUCLEAR | Fluorides | Chemical properties | electrophilic fluorination
Journal Article
Journal Article
SEMINARS IN NUCLEAR MEDICINE, ISSN 0001-2998, 01/2002, Volume 32, Issue 1, pp. 6 - 12
2-deoxy-2-[F-18] fluoro-D-glucose ((18)FDG) was developed in 1976 in a collaboration between scientists at the National Institutes of Health, the University of... 
F-18 FLUORIDE | HIGH-YIELD | 2-DEOXY-2-FLUORO-D-GLUCOSE | CONCISE COMMUNICATION | CATION-EXCHANGE | NUCLEOPHILIC-SUBSTITUTION | STEREOSPECIFIC SYNTHESIS | ACETYL HYPOFLUORITE | KRYPTOFIX 2.2.2 | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | WATER TARGET
Journal Article
APPLIED RADIATION AND ISOTOPES, ISSN 0969-8043, 08/1992, Volume 43, Issue 8, pp. 989 - 996
A protected 6-trimethylstannyl dopa derivative 6 has been synthesized for the first time as a precursor for the preparation of 6-[F-18]fluoro-L-dopa. The tin... 
F-18 ACETYL HYPOFLUORITE | NUCLEAR SCIENCE & TECHNOLOGY | ELEMENTAL FLUORINE | L-DOPA | BONDS | L-6-FLUORODOPA | CLEAVAGE | DERIVATIVES | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | CHEMISTRY, INORGANIC & NUCLEAR
Journal Article
JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, ISSN 0362-4803, 02/1998, Volume 41, Issue 2, pp. 105 - 114
Journal Article
Nuclear Medicine Communications, ISSN 0143-3636, 09/2000, Volume 21, Issue 9, pp. 799 - 802
The aim of this study was to develop a method of semi-automated 6-[F]fluoro-L-dopa (6-[F]FDOPA) synthesis using a robotic system (Scanditronix Anatech RB III,... 
L-6-FLUORODOPA | FLUORINE | F-18 ACETYL HYPOFLUORITE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | PET | HIGH-YIELD SYNTHESIS | Dihydroxyphenylalanine - isolation & purification | Fluorine Radioisotopes | Dihydroxyphenylalanine - analogs & derivatives | Dihydroxyphenylalanine - chemical synthesis
Journal Article
Journal of Fluorine Chemistry, ISSN 0022-1139, 1999, Volume 99, Issue 1, pp. 87 - 94
Differences in reactivity and selectivity of fluorine in the electrophilic fluorination of 3,4-dihydroxy phenyl-L-alanine (L-DOPA) in different solvents have... 
Fluorine-18 | Elemental fluorine | Electrophilic fluorination | 5-Fluoro-L-DOPA | fluorine-18 | RADIOFLUORINATION | TYROSINE | electrophilic fluorination | elemental fluorine | GAS | CHEMISTRY, ORGANIC | 5-fluoro-L-DOPA | ACETYL HYPOFLUORITE | F-18 | HIGH-YIELD SYNTHESIS | CHEMISTRY, INORGANIC & NUCLEAR
Journal Article
Journal of Labelled Compounds and Radiopharmaceuticals, ISSN 0362-4803, 02/2002, Volume 45, Issue 2, pp. 167 - 180
Radiohalogenated carbohydrates have been of significant interest to the Nuclear Medicine community since the success of 2‐Deoxy‐2‐fluoro‐glucose (FDG)/positron... 
3'-DEOXY-3'-FLUOROTHYMIDINE | CHEMISTRY, ANALYTICAL | CHEMISTRY, MEDICINAL | RETENTION | BIOCHEMICAL RESEARCH METHODS | FLUORINATION | ACETYL HYPOFLUORITE | F-18 FLT | POSITRON-EMISSION-TOMOGRAPHY | PHARMACOLOGY & PHARMACY | PROLIFERATION IN-VIVO | DERIVATIVES | EXPRESSION | D-GLUCOSE
Journal Article
APPLIED RADIATION AND ISOTOPES, ISSN 0969-8043, 1991, Volume 42, Issue 8, pp. 749 - 762
Data for the production of fluorine-18 (t1/2 = 109.6 min; beta+ = 100%) are reviewed. The experience of some well-established European centres for positron... 
F-18 FLUORIDE | FLUORIDE PRODUCTION | CYCLOTRON | ACETYL HYPOFLUORITE | GAS-TARGET | CHEMISTRY, INORGANIC & NUCLEAR | ANION-EXCHANGE RESIN | ROUTINE SYNTHESIS | NUCLEAR SCIENCE & TECHNOLOGY | SUPPORTED NUCLEOPHILIC-SUBSTITUTION | O-18 WATER TARGET | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | WATER
Journal Article
Applied Radiation and Isotopes, ISSN 0969-8043, 1993, Volume 44, Issue 3, pp. 527 - 536
Journal Article
Applied Radiation and Isotopes, ISSN 0969-8043, 1993, Volume 44, Issue 4, pp. 755 - 759
A method of 6-[ 18F]fluoro- l-3,4-dihydroxyphenylalanine (6-[ 18F]FDOPA) synthesis suitable for the routine production in human PET studies is described.... 
L-6-FLUORODOPA | F-18 ACETYL HYPOFLUORITE | NUCLEAR SCIENCE & TECHNOLOGY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | L-DOPA | CHEMISTRY, INORGANIC & NUCLEAR
Journal Article
APPLIED RADIATION AND ISOTOPES, ISSN 0969-8043, 04/1993, Volume 44, Issue 4, pp. 737 - 744
Asymmetric nucleophilic synthesis of 6-[F-18]fluoro-L-dopa was investigated in order to reach an enantiomeric excess of close to 100% of the L form of this... 
ASYMMETRIC-SYNTHESIS | RADIOFLUORINATION | F-18 ACETYL HYPOFLUORITE | NUCLEAR SCIENCE & TECHNOLOGY | FLUORO-L-DOPA | L-6-FLUORODOPA | FLUORINATION | ORGANOPHOSPHORUS COMPOUNDS | DERIVATIVES | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | HIGH-YIELD SYNTHESIS | CHEMISTRY, INORGANIC & NUCLEAR
Journal Article
JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, ISSN 0362-4803, 10/1995, Volume 36, Issue 10, pp. 933 - 945
Journal Article
APPLIED RADIATION AND ISOTOPES, ISSN 0969-8043, 1991, Volume 42, Issue 7, pp. 629 - 635
The NCA asymmetric synthesis of L-6-[F-18]fluorodopa starting from (1R,2R,5R)-[(+)-2-hydroxypinanyl-3-idene]glycine t-butyl ester as chiral agent has been... 
ROUTE | RADIOLOGY & NUCLEAR MEDICINE | RADIOFLUORINATION | F-18 ACETYL HYPOFLUORITE | NO-CARRIER | 6-FLUORO-L-DOPA | CHEMISTRY, INORGANIC & NUCLEAR | NUCLEAR SCIENCE & TECHNOLOGY | AMINO-ACIDS | FLUORO-L-DOPA | L-6-FLUORODOPA | DERIVATIVES | HIGH-YIELD SYNTHESIS
Journal Article
APPLIED RADIATION AND ISOTOPES, ISSN 0969-8043, 08/1992, Volume 43, Issue 8, pp. 979 - 987
A new route for the preparation of radioactively labelled alpha-methyl L-tyrosine is described. The labelling at the alpha-position has been successfully... 
PHASES | INVIVO | F-18 ACETYL HYPOFLUORITE | NUCLEAR SCIENCE & TECHNOLOGY | RESOLUTION | L-6-FLUORODOPA | FLUORINATION | 6-FLUORO-L-DOPA | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | HIGH-YIELD SYNTHESIS | CHEMISTRY, INORGANIC & NUCLEAR
Journal Article
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