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Brain Research, ISSN 0006-8993, 10/2019, Volume 1720, pp. 146297 - 146297
Transient global ischemia usually results in delayed neuronal death in selective brain regions, prior to which a rapid loss of dendritic spines has been widely... 
Dendritic spine | F-actin | Transient cerebral ischemia | Hippocampus | Index Medicus
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 09/2018, Volume 504, Issue 1, pp. 54 - 60
The β-isoform of diacylglycerol kinase (DGK) localizes predominantly to neurons and induces neurite outgrowth and spine formation. However, the detailed... 
Filopodium | Chimaerin | F-actin | Diacylglycerol kinase | Plasma membrane | Index Medicus
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 04/2009, Volume 109, Issue 1, pp. 203 - 213
Journal Article
International Journal of Biochemistry and Cell Biology, ISSN 1357-2725, 02/2018, Volume 95, pp. 17 - 26
K650M/E substitutions in the Fibroblast growth factor receptor 3 (FGFR3) are associated with Severe Achondroplasia with Developmental Delay and Acanthosis... 
F-actin | Src | FGFR3 | SADDAN | Paxillin | PLCγ1 | Index Medicus
Journal Article
Science, ISSN 0036-8075, 10/2014, Volume 346, Issue 6209, pp. 600 - 600
Linkage between the adherens junction (AJ) and the actin cytoskeleton is required for tissue development and homeostasis. In vivo findings indicated that the... 
F-ACTIN | PROTEIN | DISSOCIATION | MULTIDISCIPLINARY SCIENCES | ALPHA-E-CATENIN | VINCULIN | CELL-ADHESION MOLECULES | ADHERENS JUNCTIONS | SLIP BONDS | BETA-CATENIN | CATCH BONDS | Proteins | Tissue | Cytoskeleton | Membranes | Linkages | Binding | Filaments | Homeostasis | Biochemistry | Adhesion | Integrity
Journal Article
Nature Communications, ISSN 2041-1723, 09/2016, Volume 7, Issue 1, pp. 12886 - 12886
Mitochondria form interconnected networks that dynamically remodel in response to cellular needs. Using live-cell imaging, we investigate the role of the actin... 
ORGANIZATION | MITOSIS | OUTER-MEMBRANE | F-ACTIN | OPA1 | DNA | MULTIDISCIPLINARY SCIENCES | NEURONS | DIVISION | DRP1
Journal Article
JOURNAL OF CELL BIOLOGY, ISSN 0021-9525, 09/2015, Volume 210, Issue 6, pp. 1013 - 1031
Invasive migration in 3D extracellular matrix (ECM) is crucial to cancer metastasis, yet little is known of the molecular mechanisms that drive reorganization... 
MIGRATION | F-ACTIN | RAC | DOWNSTREAM | MOUSE MODEL | TRAFFICKING | RHO | ARP2/3 COMPLEX | DISTINCT ROLES | RETROGRADE FLOW | CELL BIOLOGY
Journal Article
MOLECULAR BIOLOGY OF THE CELL, ISSN 1059-1524, 07/2019, Volume 30, Issue 15, pp. 1781 - 1785
The emerging role of cytoskeletal proteins in the cell nucleus has become a new frontier in cell biology. Actin and actin-binding proteins regulate chromatin... 
F-ACTIN | COMPLEX | MESSENGER-RNA | HNRNP-U | GENE | INITIATION | TRANSCRIPTION | BETA-ACTIN | CELL BIOLOGY
Journal Article
Chemical Communications, ISSN 1359-7345, 2019, Volume 55, Issue 3, pp. 385 - 388
Specific effectors of actin polymerization have found use as dynamic probes of cellular morphology that may be used to gauge cellular response to stimuli and... 
TRYPTOPHAN | F-ACTIN | PROLYL OLIGOPEPTIDASE | SITE | PEPTIDES | ESTERS | CHEMISTRY | GENERATION | PHALLOTOXINS | CHEMISTRY, MULTIDISCIPLINARY | SYNTHONS
Journal Article
JOURNAL OF NEUROSCIENCE, ISSN 0270-6474, 07/2012, Volume 32, Issue 27, pp. 9143 - 9158
The correct outgrowth of axons is essential for the development and regeneration of nervous systems. Axon growth is primarily driven by microtubules. Key... 
NEURONAL MIGRATION | F-ACTIN | LOCALIZATION | DYNAMICS | TAU | OUTGROWTH | CELL | ACF7 | NEUROSCIENCES | MUSCLE-TENDON JUNCTION | DROSOPHILA
Journal Article
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 03/2019, Volume 202, Issue 5, pp. 1540 - 1548
IL-17A is a critical proinflammatory cytokine for the pathogenesis of asthma including neutrophilic pulmonary inflammation and airway hyperresponsiveness. In... 
F-ACTIN | CELLS | REGULATOR | ADHESION | MODERATE | SYNTHESIZE | IMMUNOLOGY | GTPASE | FASCIN | HYPERRESPONSIVENESS | BETA | Innate Immunity and Inflammation
Journal Article
MOLECULAR BIOLOGY OF THE CELL, ISSN 1059-1524, 04/2019, Volume 30, Issue 8, pp. 933 - 941
In many eukaryotes, cytokinesis is facilitated by the contraction of an actomyosin ring (AMR). The exact mechanisms that lead to this contractility are... 
ORGANIZATION | F-ACTIN | CONSTRICTION | CELLS | MECHANISM | DYNAMICS | CELL BIOLOGY | Brief Report
Journal Article
Molecular biology of the cell, ISSN 1059-1524, 03/2019, Volume 30, Issue 7, pp. 851 - 862
Ena/VASP tetramers are processive actin elongation factors that localize to diverse F-actin networks composed of filaments bundled by different cross-linking... 
MOLECULAR-MECHANISM | VASP | TETRAMERIZATION | F-ACTIN | IN-VITRO | DOMAIN | CYTOKINESIS | COMPLEX | BINDING PROTEINS | CELL | CELL BIOLOGY
Journal Article
Nature Communications, ISSN 2041-1723, 04/2017, Volume 8, Issue 1, pp. 14816 - 14816
Human actin-related protein 2/3 complex (Arp2/3), required for actin filament branching, has two ARPC1 component isoforms, with ARPC1B prominently expressed in... 
F-ACTIN | CELL-MIGRATION | ACTIN POLYMERIZATION | LEADING-EDGE | MULTIDISCIPLINARY SCIENCES | WISKOTT-ALDRICH-SYNDROME | SYNDROME PROTEIN | MEGAKARYOCYTE | LAMELLIPODIA | PROPLATELET FORMATION | WASP | Index Medicus
Journal Article
BIOPHYSICAL JOURNAL, ISSN 0006-3495, 10/2016, Volume 111, Issue 8, pp. 1761 - 1772
Healthy eyes contain a population of limbal stem cells (LSCs) that continuously renew the corneal epithelium. However, each year, 1 million Americans are... 
ANTIBODIES | NEGATIVE MARKER | F-ACTIN | POPULATION | STEM-CELLS | BIOPHYSICS | VISCOELASTIC PROPERTIES | KERATINOCYTE | ENRICHMENT | EXPRESSION | DEFICIENCY
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 05/2018, Volume 140, Issue 21, pp. 6513 - 6517
alpha-Amanitin is an extremely toxic bicyclic octapeptide isolated from the death-cap mushroom, Amanita phalloides. As a potent inhibitor of RNA polymerase II,... 
TRYPTOPHAN | F-ACTIN | ACID | TRYPTATHIONINE BRIDGES | TRANSCRIPTION | CONFORMATION | PEPTIDE-SYNTHESIS | PHALLOTOXINS | DERIVATIVES | CHEMISTRY, MULTIDISCIPLINARY | AMATOXINS | Index Medicus
Journal Article
TRENDS IN CELL BIOLOGY, ISSN 0962-8924, 09/2016, Volume 26, Issue 9, pp. 694 - 704
The Hippo signaling network integrates diverse upstream signals to control cell fate decisions and regulate organ growth. Recent studies have provided new... 
TISSUE-GROWTH | F-ACTIN | ORGAN SIZE | PROLIFERATION ARREST | MECHANICAL STRAIN | ALPHA-CATENIN | HIPPO PATHWAY | TUMOR-SUPPRESSOR | FAMILY PROTEINS | PROMOTES APOPTOSIS | CELL BIOLOGY
Journal Article