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1. Full Text The F-box protein TIR1 is an auxin receptor
by Dharmasiri, Nihal and Dharmasiri, Sunethra and Estelle, Mark
Nature, ISSN 0028-0836, 05/2005, Volume 435, Issue 7041, pp. 441 - 445
The plant hormone auxin regulates diverse aspects of plant growth and development. Recent studies indicate that auxin acts by promoting the degradation of the... 
SCFTIR1 | COMPLEX | MULTIDISCIPLINARY SCIENCES | GROWTH | DEGRADATION | AUX/IAA PROTEINS | MECHANISMS | ARABIDOPSIS | SCF UBIQUITIN-LIGASE | EXPRESSION | BINDING | Transcription, Genetic - drug effects | Temperature | Molecular Sequence Data | Spodoptera | Arabidopsis Proteins - metabolism | DNA-Binding Proteins - metabolism | Protein Binding - drug effects | Carrier Proteins - chemistry | Receptors, Cell Surface - chemistry | Receptors, Cell Surface - isolation & purification | Repressor Proteins - metabolism | Amino Acid Sequence | Cell Line | Arabidopsis Proteins - genetics | Indoleacetic Acids - metabolism | Signal Transduction | F-Box Proteins - metabolism | F-Box Proteins - chemistry | Receptors, Cell Surface - metabolism | Nuclear Proteins - metabolism | SKP Cullin F-Box Protein Ligases - metabolism | SKP Cullin F-Box Protein Ligases - chemistry | Arabidopsis - metabolism | Arabidopsis - genetics | Arabidopsis Proteins - isolation & purification | Carrier Proteins - genetics | Gene Expression Regulation, Plant - drug effects | Animals | Carrier Proteins - metabolism | Arabidopsis Proteins - chemistry | Indoleacetic Acids - pharmacology | Carrier Proteins - isolation & purification | F-Box Proteins - isolation & purification | F-Box Proteins - genetics | Receptors, Cell Surface - genetics | Proteins | Hormones | Physical growth | Botany
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2. Full Text Protein dynamics and conformational disorder in molecular recognition
by Mittag, Tanja and Kay, Lewis E and Forman-Kaya, Julie D
Journal of Molecular Recognition, ISSN 0952-3499, 03/2010, Volume 23, Issue 2, pp. 105 - 116
Recognition requires protein flexibility because it facilitates conformational rearrangements and induced-fit mechanisms upon target binding. Intrinsic... 
NMR | Dynamic complex | Sic1 | Disordered complex | Polyelectrostatic effect | Protein dynamics | Conformational disorder | Disorder-to-order transition | SIDE-CHAIN DYNAMICS | DEUTERIUM SPIN PROBES | dynamic complex | BIOCHEMISTRY & MOLECULAR BIOLOGY | protein dynamics | disorder-to-order transition | INTRINSICALLY UNSTRUCTURED PROTEINS | UBIQUITIN LIGASES | SUBSTRATE RECOGNITION | BIOPHYSICS | polyelectrostatic effect | HUB PROTEINS | RECEPTOR ZETA-CHAIN | STRUCTURAL DISORDER | ORDER PARAMETERS | INTERACTION NETWORKS | disordered complex | conformational disorder | Adaptor Proteins, Signal Transducing - chemistry | Receptors, Antigen, T-Cell - chemistry | Phosphorylation | Receptors, Antigen, T-Cell - metabolism | F-Box Proteins - metabolism | F-Box Proteins - chemistry | Cell Cycle Proteins - metabolism | Ubiquitin-Protein Ligases - metabolism | Models, Molecular | Cyclin-Dependent Kinase Inhibitor Proteins - metabolism | Ubiquitin-Protein Ligases - chemistry | Protein Folding | Cell Cycle Proteins - chemistry | Thermodynamics | Proteins - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Cyclin-Dependent Kinase Inhibitor Proteins - chemistry | Protein Binding | Protein Conformation | Proteins - chemistry | Adaptor Proteins, Signal Transducing - metabolism | Evolution, Molecular | Saccharomyces cerevisiae Proteins - chemistry | Binding | Proteins | Dynamics | Evolutionary | Disorders | Charge | Order disorder | Recognition
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3. Full Text Complex Regulation of the TIR1/AFB Family of Auxin Receptors
by G. Parry and L. I. Calderon-Villalobos and M. Prigge and B. Peret and S. Dharmasiri and H. Itoh and E. Lechner and W. M. Gray and M. Bennett and M. Estelle and Mark Estelle
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2009, Volume 106, Issue 52, pp. 22540 - 22545
Auxin regulates most aspects of plant growth and development. The hormone is perceived by the TIR1/AFB family of F-box proteins acting in concert with the... 
Receptors | Phenotypes | RNA | Genes | Alleles | Auxins | Gene expression regulation | Plants | Seedlings | Plant cells | Plant hormone | Plant development | plant hormone | plant development | ARABIDOPSIS-THALIANA | DOMAIN | MEMBERS | ARF | MULTIDISCIPLINARY SCIENCES | FUNCTIONAL GENOMIC ANALYSIS | BOX PROTEIN TIR1 | TRANSCRIPTIONAL REPRESSION | DEGRADATION | AUX/IAA PROTEINS | Arabidopsis Proteins - genetics | Plant Roots - metabolism | Indoleacetic Acids - metabolism | Arabidopsis - growth & development | F-Box Proteins - metabolism | Receptors, Cell Surface - metabolism | RNA, Plant - genetics | Recombinant Fusion Proteins - metabolism | Arabidopsis - metabolism | Arabidopsis - genetics | Arabidopsis Proteins - metabolism | Plant Proteins - genetics | Indoleacetic Acids - pharmacology | Plants, Genetically Modified | Gene Expression Regulation, Plant | Recombinant Fusion Proteins - genetics | MicroRNAs - genetics | Plant Proteins - metabolism | Mutation | F-Box Proteins - genetics | Genes, Plant - drug effects | Plant Roots - growth & development | Receptors, Cell Surface - genetics | Plant proteins | Auxin | Research | Arabidopsis | Growth | Proteins | Genotype & phenotype | Genetics | Plant growth | RNA, Plant | Genes, Plant | Receptors, Cell Surface | Recombinant Fusion Proteins | Life Sciences | F-Box Proteins | Arabidopsis Proteins | Plant Roots | MicroRNAs | Plant Proteins | Vegetal Biology | Indoleacetic Acids | Biological Sciences
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4. Full Text Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases
by Zhuang, Min and Calabrese, Matthew F and Liu, Jiang and Waddell, M. Brett and Nourse, Amanda and Hammel, Michal and Miller, Darcie J and Walden, Helen and Duda, David M and Seyedin, Steven N and Hoggard, Timothy and Harper, J. Wade and White, Kevin P and Schulman, Brenda A and Argonne National Lab. (ANL), Argonne, IL (United States)
Molecular Cell, ISSN 1097-2765, 10/2009, Volume 36, Issue 1, pp. 39 - 50
In the largest E3 ligase subfamily, Cul3 binds a BTB domain, and an associated protein-interaction domain such as MATH recruits substrates for ubiquitination.... 
PROTEINS | E3 LIGASE | OXIDATIVE STRESS | PROTEIN SPOP | NRF2 | BIOCHEMISTRY & MOLECULAR BIOLOGY | SCF | ADAPTER | DEGRADATION | BTB DOMAIN | F-BOX | TRANSCRIPTION FACTOR | CELL BIOLOGY | Transcription Factors - chemistry | Humans | Crystallography, X-Ray | Drosophila Proteins - metabolism | Mutation - physiology | Protein Multimerization - physiology | Protein Structure, Quaternary - physiology | Ubiquitination - physiology | Peptide Fragments - genetics | Repressor Proteins - metabolism | Amino Acid Sequence | Ubiquitin-Protein Ligases - metabolism | Models, Molecular | Repressor Proteins - genetics | Recombinant Fusion Proteins - chemistry | Nuclear Proteins - chemistry | Ubiquitin-Protein Ligases - chemistry | DNA-Binding Proteins - chemistry | Cullin Proteins - chemistry | Peptide Fragments - chemistry | Phosphoprotein Phosphatases - genetics | Consensus Sequence - physiology | Recombinant Fusion Proteins - genetics | Histones - metabolism | Ubiquitin-Protein Ligases - genetics | Drosophila melanogaster | Phosphoprotein Phosphatases - chemistry | Protein Binding - physiology | Adaptor Proteins, Signal Transducing - chemistry | Histones - chemistry | Protein Interaction Domains and Motifs - physiology | Phosphoprotein Phosphatases - metabolism | Recombinant Fusion Proteins - metabolism | DNA-Binding Proteins - metabolism | Cullin Proteins - metabolism | Nuclear Proteins - genetics | Peptide Fragments - metabolism | Repressor Proteins - chemistry | Nuclear Proteins - metabolism | Drosophila Proteins - chemistry | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Cullin Proteins - genetics | Transcription Factors - metabolism | Animals | Histones - genetics | Adaptor Proteins, Signal Transducing - genetics | Drosophila Proteins - genetics | Adaptor Proteins, Signal Transducing - metabolism | Ubiquitin | Chromatin | Phosphatases | Ligases | CHROMATIN | BASIC BIOLOGICAL SCIENCES | SUBSTRATES | FLEXIBILITY | GENERAL AND MISCELLANEOUS//MATHEMATICS, COMPUTING, AND INFORMATION SCIENCE | LIGASES | DIMERIZATION | DIMERS | PHOSPHATASES
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5. Full Text Structural biology: Breaking the protein rules
by Chouard, Tanguy
Nature, ISSN 0028-0836, 03/2011, Volume 471, Issue 7337, pp. 151 - 153
Cyclic AMP Response Element-Binding Protein - chemistry | Protein Unfolding | Humans | Calcineurin - chemistry | Structure-Activity Relationship | Cyclin-Dependent Kinase Inhibitor Proteins - metabolism | Cell Cycle Proteins - chemistry | CREB-Binding Protein - metabolism | Cyclin-Dependent Kinase Inhibitor Proteins - chemistry | Pliability | F-Box Proteins - metabolism | F-Box Proteins - chemistry | Cell Cycle Proteins - metabolism | Computational Biology | Crystallization | Tumor Suppressor Protein p53 - metabolism | Ubiquitin-Protein Ligases - metabolism | Models, Molecular | Ubiquitin-Protein Ligases - chemistry | Protein Folding | Proteins - metabolism | Models, Biological | Cyclic AMP Response Element-Binding Protein - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Protein Conformation | Tumor Suppressor Protein p53 - chemistry | Proteins - chemistry | Calcineurin - metabolism | Saccharomyces cerevisiae Proteins - chemistry
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6. Full Text Toward a NOTCH1/FBXW7/RAS/PTEN–Based Oncogenetic Risk Classification of Adult T-Cell Acute Lymphoblastic Leukemia: A Group for Research in Adult Acute Lymphoblastic Leukemia Study
by Amélie Trinquand and Aline Tanguy-Schmidt and Raouf Ben Abdelali and Jérôme Lambert and Kheira Beldjord and Etienne Lengliné and Noémie De Gunzburg and Dominique Payet-Bornet and Ludovic Lhermitte and Hossein Mossafa and Véronique Lhéritier and Jonathan Bond and Françoise Huguet and Agnès Buzyn and Thibaud Leguay and Jean-Yves Cahn and Xavier Thomas and Yves Chalandon and André Delannoy and Caroline Bonmati and Sebastien Maury and Bertrand Nadel and Elizabeth Macintyre and Norbert Ifrah and Hervé Dombret and Vahid Asnafi
Journal of Clinical Oncology, ISSN 0732-183X, 12/2013, Volume 31, Issue 34, pp. 4333 - 4342
Purpose The Group for Research in Adult Acute Lymphoblastic Leukemia (GRAALL) recently reported a significantly better outcome in T-cell acute lymphoblastic... 
ACTIVATION | THERAPY | NOTCH1 | PRETHYMIC PHENOTYPE | ONCOLOGY | PATHWAY | GENES | PTEN | MUTATIONS | EXPRESSION | F-Box-WD Repeat-Containing Protein 7 | Multivariate Analysis | Predictive Value of Tests | ras Proteins - genetics | Proto-Oncogene Proteins p21(ras) | Humans | Male | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - mortality | Young Adult | Time Factors | DNA Mutational Analysis | Gene Deletion | Cell Cycle Proteins - genetics | Adult | Female | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - therapy | PTEN Phosphohydrolase - genetics | Genetic Predisposition to Disease | Membrane Proteins - genetics | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Proto-Oncogene Proteins - genetics | Disease-Free Survival | Phenotype | GTP Phosphohydrolases - genetics | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - classification | Mutation | Receptor, Notch1 - genetics | Ubiquitin-Protein Ligases - genetics | F-Box Proteins - genetics | GTP Phosphohydrolases | ras Proteins | Innate immunity | Life Sciences | F-Box Proteins | Immunology | PTEN Phosphohydrolase | Proto-Oncogene Proteins | Membrane Proteins | Ubiquitin-Protein Ligases | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma | Receptor, Notch1 | Cell Cycle Proteins
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7. Full Text Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size
by Anne Ulrike Trendelenburg and Angelika Meyer and Daisy Rohner and Joseph Boyle and Shinji Hatakeyama and David J. Glass
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 06/2009, Volume 296, Issue 6, pp. 1258 - 1270
Myostatin is a negative regulator of skeletal muscle size, previously shown to inhibit muscle cell differentiation. Myostatin requires both Smad2 and Smad3... 
MAFbx | Mammalian target of rapamycin complex signaling | MuRF1 | S6 kinase | Smad signaling | Human skeletal muscle cells | Transducer of regulated Ca | responsive element-binding protein activity | MuRF-1 | Atrogin | Transforming growth factor-β-like molecules | IGF-I | PHYSIOLOGY | ATROPHY | RAPID DISUSE | human skeletal muscle cells | transforming growth factor-beta-like molecules | SKELETAL-MUSCLE HYPERTROPHY | FOXO TRANSCRIPTION FACTORS | UBIQUITIN LIGASES | transducer of regulated Ca2+-responsive element-binding protein activity | CELL BIOLOGY | atrogin | PATHWAY | GROWTH | GENE-EXPRESSION | mammalian target of rapamycin complex signaling | CONDITIONAL ACTIVATION | Activin Receptors, Type I - antagonists & inhibitors | Protein Kinases - metabolism | Phosphorylation | Protein Kinases - genetics | Humans | Smad3 Protein - metabolism | Muscle Fibers, Skeletal - drug effects | Tripartite Motif Proteins | Smad3 Protein - genetics | Transfection | RNA Interference | Myoblasts, Skeletal - pathology | Smad2 Protein - genetics | Muscle Proteins - metabolism | Dioxoles - pharmacology | Regulatory-Associated Protein of mTOR | Benzamides - pharmacology | Myostatin - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Rapamycin-Insensitive Companion of mTOR Protein | Ribosomal Protein S6 Kinases, 70-kDa - metabolism | Signal Transduction | Cell Size - drug effects | Cells, Cultured | Smad2 Protein - metabolism | Ubiquitin-Protein Ligases - metabolism | Organ Size | Activin Receptors, Type I - metabolism | Myoblasts, Skeletal - enzymology | SKP Cullin F-Box Protein Ligases - metabolism | Mice, SCID | Myostatin - antagonists & inhibitors | Adaptor Proteins, Signal Transducing | Animals | Carrier Proteins - metabolism | Proteins - metabolism | Cell Differentiation - drug effects | Follistatin - pharmacology | Muscle Fibers, Skeletal - pathology | Creatine Kinase - metabolism | Mice | Protein Kinase Inhibitors - pharmacology | TOR Serine-Threonine Kinases | Myoblasts, Skeletal - drug effects | Insulin-Like Growth Factor I - metabolism | Muscle Fibers, Skeletal - enzymology | RNA, Small Interfering - metabolism | Abdominal surgery | Musculoskeletal system | Signal transduction | Cell growth | Kinases | Gene expression | Cells
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8. Full Text Identification of SCF Ubiquitin Ligase Substrates by Global Protein Stability Profiling
by Hsueh-Chi Sherry Yen and Stephen J. Elledge
Science, ISSN 0036-8075, 11/2008, Volume 322, Issue 5903, pp. 923 - 929
Ubiquitin-mediated proteolysis regulates all aspects of cellular function, and defects in this process are associated with human diseases. The limited number... 
Proteins | Polymerase chain reaction | DNA | Cell cycle | Cell lines | Viruses | Protein stability | Libraries | Research Articles | Open reading frames | F box proteins | COMPLEX | CYCLIN-E | PATHWAY | MULTIDISCIPLINARY SCIENCES | F-BOX PROTEINS | S-PHASE | DEGRADATION | KAPPA-B-ALPHA | BETA-CATENIN | HISTONE MESSENGER-RNA | REVEALS | Oligonucleotide Array Sequence Analysis | SKP Cullin F-Box Protein Ligases - genetics | Humans | Open Reading Frames | Half-Life | Substrate Specificity | Proteins - isolation & purification | Recombinant Fusion Proteins - metabolism | Luminescent Proteins - analysis | Cullin Proteins - metabolism | Protein Stability | cdc25 Phosphatases - metabolism | Cell Line | Green Fluorescent Proteins - metabolism | Cell Cycle Proteins - isolation & purification | cdc25 Phosphatases - isolation & purification | Green Fluorescent Proteins - analysis | Signal Transduction | Cell Cycle Proteins - metabolism | SKP Cullin F-Box Protein Ligases - metabolism | SKP Cullin F-Box Protein Ligases - antagonists & inhibitors | Cullin Proteins - genetics | Proteins - genetics | Proteins - metabolism | Cell Cycle | Apoptosis | Luminescent Proteins - metabolism | Evaluation | Protein research | Substrates (Biochemistry) | Proteolysis | Research | Ubiquitin-proteasome system | Properties | Genetics | Cellular biology | Research methodology | Substrates
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9. Full Text Polo-like Kinase-1 Regulates Myc Stabilization and Activates a Feedforward Circuit Promoting Tumor Cell Survival
by Xiao, Daibiao and Yue, Ming and Su, Hexiu and Ren, Ping and Jiang, Jue and Li, Feng and Hu, Yufeng and Du, Haining and Liu, Hudan and Qing, Guoliang
Molecular Cell, ISSN 1097-2765, 11/2016, Volume 64, Issue 3, pp. 493 - 506
amplification in human cancers predicts poor prognosis and resistance to therapy. However, pharmacological strategies that directly target N-Myc, the protein... 
BI6727 | targeted therapy | ubiquitination | Myc | PLK1 | neuroblastoma | Fbw7 | small cell lung carcinoma | ABT199 | TARGETED THERAPY | INHIBITOR VOLASERTIB | BIOCHEMISTRY & MOLECULAR BIOLOGY | N-MYC | C-MYC | F-BOX PROTEINS | AMPLIFIED NEUROBLASTOMA | AURORA KINASE | FBW7 UBIQUITIN LIGASE | CANCER-THERAPY | HUMAN NEUROBLASTOMA | CELL BIOLOGY | RNA, Small Interfering - genetics | Humans | Neuroblastoma - mortality | N-Myc Proto-Oncogene Protein - antagonists & inhibitors | Transcription, Genetic | Neurons - metabolism | Brain Neoplasms - mortality | Protein-Serine-Threonine Kinases - metabolism | Signal Transduction | Cell Cycle Proteins - metabolism | Ubiquitin-Protein Ligases - metabolism | Brain Neoplasms - genetics | Brain Neoplasms - drug therapy | Sulfonamides - pharmacology | Drug Synergism | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Feedback, Physiological | Mice, Nude | Survival Analysis | Cell Line, Tumor | Ubiquitin-Protein Ligases - genetics | F-Box Proteins - genetics | RNA, Small Interfering - metabolism | F-Box-WD Repeat-Containing Protein 7 | Neurons - pathology | Brain Neoplasms - pathology | Gene Expression Regulation, Neoplastic | N-Myc Proto-Oncogene Protein - genetics | Cell Cycle Proteins - antagonists & inhibitors | Proto-Oncogene Proteins c-bcl-2 - metabolism | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Cell Cycle Proteins - genetics | Antineoplastic Agents - pharmacology | Neurons - drug effects | Neuroblastoma - pathology | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | Pteridines - pharmacology | F-Box Proteins - metabolism | Neuroblastoma - genetics | Protein-Serine-Threonine Kinases - genetics | Proto-Oncogene Proteins - genetics | Xenograft Model Antitumor Assays | Animals | Tumor Burden - drug effects | N-Myc Proto-Oncogene Protein - metabolism | Neuroblastoma - drug therapy | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Proto-Oncogene Proteins c-bcl-2 - genetics | Ubiquitin | Polo | Ligases | Lung cancer | Therapeutics | Homeopathy | Materia medica and therapeutics | Cancer
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10. Full Text Signalling pathways regulating muscle mass in ageing skeletal muscle. The role of the IGF1-Akt-mTOR-FoxO pathway
by Sani, M and Barberi, L and Bijlsma, A.Y and Blaauw, B and Dyar, K.A and Milan, G and Mammucari, C and Meskers, C.G.M and Pallafacchina, G and Paoli, A and Pion, D and Roceri, M and Romanello, V and Serrano, A.L and Toniolo, L and Larsson, L and Maier, A.B and Munoz-Canoves, P and Musaro, A and Pende, M and Reggiani, C and Rizzuto, R and Schiaffino, S and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Uppsala universitet and Klinisk neurofysiologi and Institutionen för neurovetenskap
Biogerontology, ISSN 1389-5729, 2013, Volume 14, Issue 3, pp. 303 - 323
During ageing skeletal muscles undergo a process of structural and functional remodelling that leads to sarcopenia, a syndrome characterized by loss of muscle... 
Life Sciences | Sarcopenia | FoxO | Geriatrics/Gerontology | Ageing | mTOR | IGF1 | Akt | Developmental Biology | Cell Biology | LIFE-SPAN | IGF-I | ALPHA-V-BETA-3 INTEGRIN | PLASMINOGEN-ACTIVATOR INHIBITOR-1 | GERIATRICS & GERONTOLOGY | GROWTH-HORMONE | MESSENGER-RNA | GENETIC-DETERMINANTS | FAST-TWITCH | CELL-CYCLE | S6 KINASE | Microtubule-Associated Proteins - genetics | SKP Cullin F-Box Protein Ligases - genetics | Humans | SKP Cullin F-Box Protein Ligases - physiology | Male | Forkhead Transcription Factors - physiology | Ubiquitin-Protein Ligases - physiology | Tripartite Motif Proteins | Young Adult | Aged, 80 and over | Adult | Female | Mice, Inbred DBA | Models, Animal | TOR Serine-Threonine Kinases - physiology | Muscle Proteins - physiology | Serpin E2 - physiology | Mice, Inbred C57BL | Mice, Transgenic | Proto-Oncogene Proteins c-akt - physiology | Muscle, Skeletal - physiology | Mice, Knockout | Microtubule-Associated Proteins - physiology | Muscle Proteins - genetics | Autophagy-Related Protein 7 | Sarcopenia - physiopathology | Serpin E2 - genetics | Animals | Aging - physiology | Insulin-Like Growth Factor I - physiology | Adolescent | Signal Transduction - physiology | Aged | Forkhead Box Protein O1 | Mice | Ubiquitin-Protein Ligases - genetics | Ubiquitin | Muscles | Ligases | Proteolysis | Analysis | SKP Cullin F-Box Protein Ligases | Muscle Proteins | Aging | Serpin E2 | Signal Transduction | Biochemistry, Molecular Biology | Microtubule-Associated Proteins | Insulin-Like Growth Factor I | Proto-Oncogene Proteins c-akt | Ubiquitin-Protein Ligases | TOR Serine-Threonine Kinases | Muscle, Skeletal | Forkhead Transcription Factors | Clinical Medicine | Neurology | Neurologi | Medical and Health Sciences | Medicin och hälsovetenskap | Clinical Neurophysiology | Klinisk neurofysiologi | Klinisk medicin
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11. Full Text The Arabidopsis F-box protein TIR1 is an auxin receptor
by Kepinski, Stefan and Leyser, Ottoline
Nature, ISSN 0028-0836, 05/2005, Volume 435, Issue 7041, pp. 446 - 451
Despite 100 years of evidence showing a pivotal role for indole-3-acetic acid (IAA or auxin) in plant development, the mechanism of auxin perception has... 
PLANT | SCFTIR1 | COMPLEX | REPRESSION | GENETICS | PATHWAY | MULTIDISCIPLINARY SCIENCES | SCF | DEGRADATION | AUX/IAA PROTEINS | UBIQUITIN LIGASES | Transcription, Genetic - drug effects | Immunoprecipitation | Molecular Sequence Data | Arabidopsis Proteins - metabolism | DNA-Binding Proteins - metabolism | Carrier Proteins - chemistry | Receptors, Cell Surface - chemistry | Amino Acid Sequence | Arabidopsis Proteins - genetics | Indoleacetic Acids - metabolism | F-Box Proteins - metabolism | Oocytes - metabolism | F-Box Proteins - chemistry | Xenopus laevis | Receptors, Cell Surface - metabolism | Nuclear Proteins - metabolism | SKP Cullin F-Box Protein Ligases - metabolism | SKP Cullin F-Box Protein Ligases - chemistry | Arabidopsis - metabolism | Arabidopsis - genetics | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Arabidopsis Proteins - chemistry | Indoleacetic Acids - pharmacology | Protein Binding | F-Box Proteins - genetics | Receptors, Cell Surface - genetics | Proteins | Hormones | Gene expression | Binding sites | Botany
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