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f-box-wd repeat-containing protein 7 (474) 474
ubiquitin-protein ligases - genetics (318) 318
f-box proteins - genetics (316) 316
cell cycle proteins - genetics (294) 294
f-box proteins - metabolism (270) 270
ubiquitin-protein ligases - metabolism (270) 270
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phosphorylation (137) 137
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article (85) 85
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tumors (62) 62
gene (59) 59
cell line (58) 58
receptor, notch1 - genetics (56) 56
differentiation (55) 55
gene expression (55) 55
f-box-wd repeat-containing protein 7 - genetics (54) 54
f-box proteins (52) 52
cyclin e - metabolism (50) 50
fbw7 ubiquitin ligase (46) 46
health aspects (46) 46
ligases (46) 46
multidisciplinary sciences (46) 46
micrornas - genetics (44) 44
mutations (44) 44
protein binding (44) 44
protein stability (44) 44
glycogen synthase kinase 3 - metabolism (43) 43
hek293 cells (43) 43
genetics & heredity (42) 42
mice, knockout (42) 42
activation (41) 41
f-box proteins - physiology (41) 41
hematology (41) 41
ubiquitin-protein ligases - physiology (41) 41
genes (40) 40
molecular sequence data (40) 40
rna interference (40) 40
chromosomal instability (39) 39
analysis (38) 38
cdc4 protein (38) 38
f-box-wd repeat-containing protein 7 - metabolism (38) 38
proteasome endopeptidase complex - metabolism (38) 38
acute lymphoblastic-leukemia (37) 37
amino acid sequence (36) 36
cells (36) 36
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mice, nude (34) 34
proto-oncogene proteins c-myc - genetics (34) 34
tumor suppressor protein p53 - genetics (34) 34
breast-cancer (33) 33
cell cycle proteins - physiology (33) 33
precursor t-cell lymphoblastic leukemia-lymphoma - genetics (33) 33
transcription factors (33) 33
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1. Full Text Overexpression of miR-92a promotes the tumor growth of osteosarcoma by suppressing F-box and WD repeat-containing protein 7
by Jiang, Xuesheng and Li, Xiongfeng and Li, Jianyou and Wu, Fengfeng and Gao, Hongliang and Wang, Huajun and Wang, Guorong and Zheng, Hua and Chen, Chao
Gene, ISSN 0378-1119, 03/2017, Volume 606, pp. 10 - 16
MicroRNAs (miRNAs) have been reported to be critical players in osteosarcoma (OS). Among numerous cancer-related miRNAs, the expression level of miR-92a and... 
Cell cycle progression | Proliferation | Osteosarcoma | FBXW7 | miR-92a | Apoptosis | CELLS | METASTASIS | HEPATOCELLULAR-CARCINOMA | GENETICS & HEREDITY | TARGETING FBXW7 | HUMAN CANCERS | MICRORNA | F-Box-WD Repeat-Containing Protein 7 | F-Box Proteins - metabolism | Humans | Cell Cycle Proteins - metabolism | Gene Expression Regulation, Neoplastic | Ubiquitin-Protein Ligases - metabolism | MicroRNAs - metabolism | Animals | Mice, Nude | Bone and Bones - metabolism | Cell Line, Tumor | Mice | Osteosarcoma - genetics | Osteosarcoma - pathology | Development and progression | Tumors | Index Medicus
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2. Full Text Increased incidence of FBXW7 and POLE proofreading domain mutations in young adult colorectal cancers
by Kothari, Nishi and Teer, Jamie K and Abbott, Andrea M and Srikumar, Thejal and Zhang, Yonghong and Yoder, Sean J and Brohl, Andrew S and Kim, Richard D and Reed, Damon R and Shibata, David
Cancer, ISSN 0008-543X, 09/2016, Volume 122, Issue 18, pp. 2828 - 2835
The authors describe their original research involving exome sequencing of patients with colorectal cancer in which younger patients were compared with older... 
adolescent and young adults | colorectal cancer | biomarkers | F‐box and WD repeat‐containing protein 7 (FBXW7) | Adolescent and young adults | Biomarkers | F-box and WD repeat-containing protein 7 (FBXW7) | Colorectal cancer | UNITED-STATES | SURVIVAL | STATISTICS | POLYMERASE | DISCOVERY | ADOLESCENT | BREAST-CANCER | IMPACT | GENOMICS | ONCOLOGY | ACUTE LYMPHOBLASTIC-LEUKEMIA | F-Box-WD Repeat-Containing Protein 7 | Colorectal Neoplasms - enzymology | Age Factors | F-Box Proteins - metabolism | Colorectal Neoplasms - genetics | Humans | Middle Aged | Cell Cycle Proteins - metabolism | Ubiquitin-Protein Ligases - metabolism | Male | DNA Polymerase II - metabolism | Incidence | Poly-ADP-Ribose Binding Proteins | Aged, 80 and over | Cell Cycle Proteins - genetics | Female | Aged | Retrospective Studies | Mutation | Colorectal Neoplasms - pathology | Ubiquitin-Protein Ligases - genetics | DNA Polymerase II - genetics | F-Box Proteins - genetics | Cohort Studies | Diagnosis | Demographic aspects | Patient outcomes | Index Medicus | Abridged Index Medicus | AYA | iomarkers
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3. Full Text Colorectal Cancer Stem Cells Acquire Chemoresistance Through the Upregulation of F‐Box/WD Repeat‐Containing Protein 7 and the Consequent Degradation of c‐Myc
by Izumi, Daisuke and Ishimoto, Takatsugu and Miyake, Keisuke and Eto, Tsugio and Arima, Kota and Kiyozumi, Yuki and Uchihara, Tomoyuki and Kurashige, Junji and Iwatsuki, Masaaki and Baba, Yoshifumi and Sakamoto, Yasuo and Miyamoto, Yuji and Yoshida, Naoya and Watanabe, Masayuki and Goel, Ajay and Tan, Patrick and Baba, Hideo
STEM CELLS, ISSN 1066-5099, 09/2017, Volume 35, Issue 9, pp. 2027 - 2036
The cancer stem cell (CSC) paradigm suggests that tumors are organized hierarchically. Chugai previously established an LGR5 + human colorectal cancer (CRC)... 
Cancer stem cells | F‐box/WD repeat‐containing protein 7 | c‐Myc | Colorectal cancer | Chemoresistance | F-box/WD repeat-containing protein 7 | c-Myc | INITIATING CELLS | HEMATOPOIETIC-CELL | COLON | IDENTIFICATION | CHROMOSOMAL INSTABILITY | CELL & TISSUE ENGINEERING | CELL BIOLOGY | GENE | ONCOLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | DIFFERENTIATION | LEUKEMIA | HEMATOLOGY | TUMOR-GROWTH | EXPRESSION | Receptors, G-Protein-Coupled - metabolism | Neoplastic Stem Cells - drug effects | Colorectal Neoplasms - genetics | Humans | Antineoplastic Agents - therapeutic use | F-Box-WD Repeat-Containing Protein 7 - genetics | Proteolysis - drug effects | Neoplastic Stem Cells - metabolism | Colorectal Neoplasms - drug therapy | Neoplastic Stem Cells - pathology | Liver Neoplasms - pathology | Antineoplastic Agents - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Liver Neoplasms - secondary | Proto-Oncogene Proteins c-myc - metabolism | Down-Regulation - genetics | Up-Regulation - drug effects | Drug Resistance, Neoplasm - genetics | Animals | Cell Line, Tumor | Mice | Receptors, G-Protein-Coupled - genetics | Colorectal Neoplasms - pathology | F-Box-WD Repeat-Containing Protein 7 - metabolism | Drug Resistance, Neoplasm - drug effects | Cell death | Liver | Colorectal carcinoma | c-Myc protein | Myc protein | Drug resistance | Cdc4 protein | Metastases | Anticancer properties | Antitumor agents | Cell cycle | siRNA | Tumor cell lines | Irinotecan | Chemotherapy | Molecular modelling | Overexpression | Ribonucleic acids | Stem cells | Regulatory mechanisms (biology) | Sensitivity enhancement | Differentiation | Tumors | Cancer | Index Medicus
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4. Full Text Fbxw7 regulates lipid metabolism and cell fate decisions in the mouse liver
by Onoyama, Ichiro and Suzuki, Atsushi and Matsumoto, Akinobu and Tomita, Kengo and Katagiri, Hideki and Oike, Yuichi and Nakayama, Keiko and Nakayama, Keiichi I
Journal of Clinical Investigation, ISSN 0021-9738, 01/2011, Volume 121, Issue 1, pp. 342 - 354
E3 ubiquitin ligase complexes of the SCF type consist of ring-box 1 (Rbx1), cullin 1 (Cull), S-phase kinase-associated protein 1 (Skp1), and a member of the... 
MEDICINE, RESEARCH & EXPERIMENTAL | CYCLIN-E | TUBEROUS SCLEROSIS GENE | SCFFBW7 UBIQUITIN LIGASE | C-MYC | TUMOR-SUPPRESSOR | NONALCOHOLIC STEATOHEPATITIS | T-CELL | KNOCKOUT MICE | PHOSPHORYLATION-DEPENDENT DEGRADATION | F-BOX PROTEIN | F-Box-WD Repeat-Containing Protein 7 | Liver - pathology | Fatty Liver - pathology | Humans | Hepatocytes - pathology | DNA Primers - genetics | Hepatocytes - metabolism | Stem Cells - metabolism | Cell Differentiation - genetics | Lipogenesis - genetics | Mice, Mutant Strains | Base Sequence | Female | Lipid Metabolism - genetics | Adipogenesis - genetics | Cell Differentiation - physiology | Disease Models, Animal | Fatty Liver - genetics | Gene Expression | Fatty Liver - metabolism | F-Box Proteins - metabolism | Liver - metabolism | Ubiquitin-Protein Ligases - metabolism | Mice, Transgenic | Mice, Knockout | Pregnancy | Animals | Models, Biological | Stem Cells - pathology | Ubiquitin-Protein Ligases - deficiency | Liver - cytology | Mice | Ubiquitin-Protein Ligases - genetics | F-Box Proteins - genetics | Lipid Metabolism - physiology | Cell proliferation | Genes | Liver | Physiological aspects | Genetic aspects | Research | Lipid metabolism | Index Medicus | Abridged Index Medicus
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5. Promotional effect of microRNA-194 on breast cancer cells via targeting F-box/WD repeat-containing protein 7
by Chen, Yaomin and Wei, Haiyan and Liu, Yu and Zheng, Shusen
Oncology Letters, ISSN 1792-1074, 04/2018, Volume 15, Issue 4, pp. 4439 - 4444
Breast cancer is the most common type of malignant cancer in females. An increasing number of studies have revealed that microRNAs (miR), which belong to a... 
Breast cancer | MicroRNA | Proliferation | F-box/WD repeat-containing protein 7 | FBXW7 EXPRESSION | CYCLIN-E | SEL-10 | proliferation | C-MYC | breast cancer | GENE | ONCOLOGY | GASTRIC-CANCER | PATHWAY | MIRNA | microRNA | MIR-194
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6. Full Text miR-367 promotes the proliferation and invasion of non-small cell lung cancer via targeting FBXW7
by Xu, Jing and Wu, Weibing and Wang, Jun and Huang, Chenjun and Wen, Wei and Zhao, Fei and Xu, Xinfeng and Pan, Xianglong and Wang, Wei and Zhu, Quan and Chen, Liang
Oncology Reports, ISSN 1021-335X, 01/2017, Volume 37, Issue 2, pp. 1052 - 1058
The involvement of miR-367 in lung cancer development remains unclear. In the present study, we analyzed the expression of miR-367 in tumor and adjacent tissue... 
miR-367 | NSCLC | proliferation | invasion | FBXW7 | Proliferation | Invasion | CYCLIN-E | TUMOR-SUPPRESSOR GENE | DOWN-REGULATION | C-MYC | CERVICAL-CANCER | MCL-1 DEGRADATION | HEPATOCELLULAR-CARCINOMA | ONCOLOGY | GASTRIC-CANCER | COLORECTAL-CANCER | ACUTE LYMPHOBLASTIC-LEUKEMIA | F-Box-WD Repeat-Containing Protein 7 | Lung Neoplasms - mortality | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Apoptosis - genetics | Lung Neoplasms - pathology | Male | MicroRNAs - metabolism | Biomarkers, Tumor - metabolism | Cell Cycle Proteins - genetics | Female | 3' Untranslated Regions | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Cell Proliferation - genetics | Carcinoma, Non-Small-Cell Lung - genetics | F-Box Proteins - metabolism | Cell Cycle Proteins - metabolism | Ubiquitin-Protein Ligases - metabolism | Carcinoma, Non-Small-Cell Lung - mortality | Cell Line, Tumor | Aged | Biomarkers, Tumor - genetics | MicroRNAs - genetics | Ubiquitin-Protein Ligases - genetics | F-Box Proteins - genetics | Cellular proteins | Care and treatment | MicroRNA | Development and progression | Genetic aspects | Lung cancer, Non-small cell | Gene expression | Health aspects | Biotechnology | Thoracic surgery | Immunoglobulins | Lung cancer | Metastasis | Experiments | Cancer therapies | Proteins | Chemotherapy | Plasmids | Medical prognosis | Surgery | MicroRNAs | Binding sites | Apoptosis | Index Medicus
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7. Full Text Stringent control of NFE2L3 (Nuclear Factor, Erythroid 2-Like 3; NRF3) protein degradation by FBW7 (F-box/WD Repeatcontaining Protein 7) and glycogen synthase kinase 3 (GSK3)
by Kannan, Meenakshi B and Dodard-Friedman, Isadore and Blank, Volker
Journal of Biological Chemistry, ISSN 0021-9258, 10/2015, Volume 290, Issue 43, pp. 26292 - 26302
The NFE2L3 transcription factor has been implicated in various cellular processes, including carcinogenesis, stress response, differentiation, and... 
LEUCINE-ZIPPER | MAF | MULTIUBIQUITIN CHAIN | GENE | UBIQUITIN LIGASE | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | TUMOR-SUPPRESSOR | CELL-CYCLE | TRANSCRIPTION FACTOR NF-E2 | Cell Line | F-Box-WD Repeat-Containing Protein 7 | Phosphorylation | Basic-Leucine Zipper Transcription Factors - metabolism | F-Box Proteins - metabolism | Humans | Cell Cycle Proteins - metabolism | Ubiquitin - metabolism | Ubiquitin-Protein Ligases - metabolism | Glycogen Synthase Kinase 3 - metabolism | Ubiquitination | Proteolysis | Proteasome Endopeptidase Complex - metabolism | Dimerization | Index Medicus | ubiquitin ligase | GSK3 | ubiquitination | Protein Synthesis and Degradation | NFE2L3 | E3 ubiquitin ligase | FBW7 | oxidative stress | protein degradation | ubiquitin
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8. Full Text Ampelopsin induces apoptosis by regulating multiple c-Myc/S-phase kinase-associated protein 2/F-box and WD repeat-containing protein 7/histone deacetylase 2 pathways in human lung adenocarcinoma cells
by CHEN, XIN-MEI and XIE, XIAN-BIAO and ZHAO, QING and WANG, FANG and BAI, YANG and YIN, JUN-QIANG and JIANG, HONG and XIE, XIAO-LIN and JIA, QIANG and HUANG, GANG
Molecular Medicine Reports, ISSN 1791-2997, 1/2015, Volume 11, Issue 1, pp. 105 - 112
Ampelopsin (AMP), a plant flavonoid, has been reported to inhibit cell growth and/or induce apoptosis in various types of tumor. The aim of the present study... 
lung cancer | ampelopsin | F-box/WD repeat-containing protein 7 | c-Myc | S-phase kinase-associated protein 2 | C-Myc | Ampelopsin | Lung cancer | MEDICINE, RESEARCH & EXPERIMENTAL | PHOSPHORYLATION | MITOGENS | MECHANISMS | PROTEOLYSIS | CANCER | WD repeat-containing protein 7 | F-box | ONCOLOGY | UBIQUITYLATION | DEGRADATION | INHIBITORS | FBW7 | TRANSCRIPTION FACTOR | F-Box-WD Repeat-Containing Protein 7 | Adenocarcinoma - pathology | Adenocarcinoma of Lung | Apoptosis - drug effects | Humans | Lung Neoplasms - metabolism | Gene Expression Regulation, Neoplastic | Lung Neoplasms - pathology | Membrane Potential, Mitochondrial - drug effects | RNA, Messenger - metabolism | Adenocarcinoma - metabolism | Adenocarcinoma - genetics | Adenosine Monophosphate - pharmacology | Flavonoids - pharmacology | Lung Neoplasms - genetics | Histone Deacetylase 2 - genetics | Adenosine Monophosphate - metabolism | F-Box Proteins - metabolism | RNA, Messenger - genetics | Cell Cycle Proteins - metabolism | Ubiquitin-Protein Ligases - metabolism | S-Phase Kinase-Associated Proteins - metabolism | Proto-Oncogene Proteins c-myc - metabolism | Signal Transduction - drug effects | Cell Line, Tumor | S-Phase Kinase-Associated Proteins - genetics | Cell Proliferation - drug effects | Proto-Oncogene Proteins c-myc - genetics | Histone Deacetylase 2 - metabolism | Flavonoids | Care and treatment | Flavones | Bioflavonoids | Genetic aspects | Research | Health aspects | Risk factors | Apoptosis | Cell proliferation | Adenocarcinoma | Cell culture | Flow cytometry | Histone deacetylase | Phosphorylation | Transcription factors | Bcl-2 protein | Epithelial cells | Leukemia | c-Myc protein | Reverse transcription | Propidium iodide | Myc protein | Drug resistance | Kinases | Western blotting | Plant cells | Cell adhesion & migration | Proteins | Cell growth | Enzymes | AMP | Glycogen | Glycogen synthase kinase 3 | Cell division | Breast cancer | Gene expression | Lymphoma | Polymerase chain reaction | Lymphocytes B | Annexin V | B-cell lymphoma
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9. Full Text Ampelopsin induces apoptosis by regulating multiple c-Myc/S-phase kinase-associated protein 2/F-box and WD repeat-containing protein 7/histone deacetylase 2 pathways in human lung adenocarcinoma cells
by Chen, Xin-Mei and Xie, Xian-Biao and Zhao, Qing and Wang, Fang and Bai, Yang and Yin, Jun-Qiang and Jiang, Hong and Xie, Xiao-Lin and Jia, Qiang and Huang, Gang
Molecular Medicine Reports, ISSN 1791-2997, 01/2015, Volume 11, Issue 1, pp. 105 - 112
Ampelopsin | F-box/WD repeat-containing protein 7 | Lung cancer | S-phase kinase-associated protein 2 | C-Myc
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10. Full Text Novel Role of FBXW7 Circular RNA in Repressing Glioma Tumorigenesis
by Yang, Yibing and Gao, Xinya and Zhang, Maolei and Yan, Sheng and Sun, Chengjun and Xiao, Feizhe and Huang, Nunu and Yang, Xuesong and Zhao, Kun and Zhou, Huangkai and Huang, Suyun and Xie, Bo and Zhang, Nu
Journal of the National Cancer Institute, ISSN 0027-8874, 03/2018, Volume 110, Issue 3, pp. 304 - 315
Background: Circular RNAs (circRNAs) are RNA transcripts that are widespread in the eukaryotic genome. Recent evidence indicates that circRNAs play important... 
TRANSCRIPTS | ABUNDANT | MYC STABILITY | DATABASE | ONCOLOGY | UBIQUITIN LIGASE | TUMOR-SUPPRESSOR | F-BOX | FBW7 | TRANSLATION | EXON CIRCULARIZATION | Cell Cycle - genetics | F-Box-WD Repeat-Containing Protein 7 | Neoplasm Transplantation | Up-Regulation | Cell Cycle Proteins - analysis | Humans | Open Reading Frames | Half-Life | Brain - metabolism | Glioblastoma - genetics | Cell Transformation, Neoplastic - genetics | Ubiquitin-Protein Ligases - analysis | Cell Cycle Proteins - genetics | Ubiquitin Thiolesterase - metabolism | Female | Glioblastoma - chemistry | F-Box Proteins - analysis | Brain Neoplasms - chemistry | Cell Proliferation - genetics | RNA - analysis | Brain Neoplasms - genetics | Survival Rate | Proto-Oncogene Proteins c-myc - metabolism | Animals | Sequence Analysis, RNA | Mice, Nude | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Ubiquitin-Protein Ligases - genetics | F-Box Proteins - genetics | Index Medicus
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11. Full Text Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7
by Wertz, Ingrid E and Kusam, Saritha and Lam, Cynthia and Okamoto, Toru and Sandoval, Wendy and Anderson, Daniel J and Helgason, Elizabeth and Ernst, James A and Eby, Mike and Liu, Jinfeng and Belmont, Lisa D and Kaminker, Josh S and O'Rourke, Karen M and Pujara, Kanan and Kohli, Pawan Bir and Johnson, Adam R and Chiu, Mark L and Lill, Jennie R and Jackson, Peter K and Fairbrother, Wayne J and Seshagiri, Somasekar and Ludlam, Mary J. C and Leong, Kevin G and Dueber, Erin C and Maecker, Heather and Huang, David C. S and Dixit, Vishva M
Nature, ISSN 0028-0836, 03/2011, Volume 471, Issue 7336, pp. 110 - 114
Microtubules have pivotal roles in fundamental cellular processes and are targets of antitubulin chemotherapeutics(1). Microtubule-targeted agents such as... 
CELLS | APOPTOSIS | CATALYZES | UBIQUITIN LIGASE | MULTIDISCIPLINARY SCIENCES | MITOTIC EXIT | RESISTANCE | PROTEINS | CANCER | DIVISION | F-Box-WD Repeat-Containing Protein 7 | Vincristine - pharmacology | Paclitaxel - pharmacology | Apoptosis - drug effects | Tubulin Modulators - pharmacology | Humans | Drug Resistance, Neoplasm | RNA, Messenger - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | Tubulin - metabolism | Protein Binding - drug effects | Cell Cycle Proteins - genetics | Fibroblasts | Phosphorylation - drug effects | Cell Line | Pharmacogenetics | Polyploidy | F-Box Proteins - metabolism | RNA, Messenger - genetics | Cell Cycle Proteins - metabolism | Ubiquitin-Protein Ligases - metabolism | Proto-Oncogene Proteins c-bcl-2 - deficiency | Animals | Mitosis - drug effects | Myeloid Cell Leukemia Sequence 1 Protein | Cell Line, Tumor | Ubiquitin-Protein Ligases - deficiency | Mice | Cell Transformation, Neoplastic - drug effects | Proteasome Endopeptidase Complex - metabolism | Ubiquitin-Protein Ligases - genetics | F-Box Proteins - genetics | Proto-Oncogene Proteins c-bcl-2 - genetics | Proteins | Cell death | Cellular control mechanisms | Causes of | Physiological aspects | Genetic aspects | Models | Phosphorylation | Kinases | Arrests | Mass spectrometry | Apoptosis | Index Medicus
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12. Full Text Landscape of genomic alterations in cervical carcinomas
by Ojesina, Akinyemi I and Lichtenstein, Lee and Freeman, Samuel S and Pedamallu, Chandra Sekhar and Imaz-Rosshandler, Ivan and Pugh, Trevor J and Cherniack, Andrew D and Ambrogio, Lauren and Cibulskis, Kristian and Bertelsen, Bjørn and Romero-Cordoba, Sandra and Treviño, Victor and Vazquez-Santillan, Karla and Guadarrama, Alberto Salido and Wright, Alexi A and Rosenberg, Mara W and Duke, Fujiko and Kaplan, Bethany and Wang, Rui and Nickerson, Elizabeth and Walline, Heather M and Lawrence, Michael S and Stewart, Chip and Carter, Scott L and McKenna, Aaron and Rodriguez-Sanchez, Iram P and Espinosa-Castilla, Magali and Woie, Kathrine and Bjorge, Line and Wik, Elisabeth and Halle, Mari K and Hoivik, Erling A and Krakstad, Camilla and Gabiño, Nayeli Belem and Gómez-Macías, Gabriela Sofia and Valdez-Chapa, Lezmes D and Garza-Rodríguez, María Lourdes and Maytorena, German and Vazquez, Jorge and Rodea, Carlos and Cravioto, Adrian and Cortes, Maria L and Greulich, Heidi and Crum, Christopher P and Neuberg, Donna S and Hidalgo-Miranda, Alfredo and Escareno, Claudia Rangel and Akslen, Lars A and Carey, Thomas E and Vintermyr, Olav K and Gabriel, Stacey B and Barrera-Saldaña, Hugo A and Melendez-Zajgla, Jorge and Getz, Gad and Salvesen, Helga B and Meyerson, Matthew
Nature, ISSN 0028-0836, 2014, Volume 506, Issue 7488, pp. 371 - 375
Cervical cancer is responsible for 10-15% of cancer-related deaths in women worldwide(1,2). The aetiological role of infection with high-risk human papilloma... 
DOMAIN | CATALOG | FUSION | MULTIDISCIPLINARY SCIENCES | FRAMEWORK | HUMAN-PAPILLOMAVIRUS | SENSITIVE DETECTION | CANCER | EXPRESSION | SOMATIC MUTATIONS | DISCOVERY | F-Box-WD Repeat-Containing Protein 7 | Receptor, ErbB-2 - genetics | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - virology | Genomics | Humans | E1A-Associated p300 Protein - genetics | Core Binding Factor beta Subunit - genetics | Case-Control Studies | Papillomaviridae - genetics | Tumor Suppressor Protein p53 - genetics | DNA Mutational Analysis | Mitogen-Activated Protein Kinase 1 - genetics | Cell Cycle Proteins - genetics | Female | NF-E2-Related Factor 2 - genetics | Adenocarcinoma - genetics | Papillomaviridae - physiology | HLA-B Antigens - genetics | Gene Expression Regulation, Neoplastic - genetics | Proto-Oncogene Proteins c-ets | Virus Integration - genetics | Proto-Oncogene Proteins - genetics | DNA Copy Number Variations - genetics | Transcriptome - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Mutation - genetics | Uterine Cervical Neoplasms - genetics | Adenocarcinoma - virology | Genome, Human - genetics | Papillomavirus Infections - genetics | Exome - genetics | Uterine Cervical Neoplasms - virology | Ubiquitin-Protein Ligases - genetics | F-Box Proteins - genetics | Prevention | Gene mutations | Oncology, Experimental | Exome sequencing | Genetic aspects | Research | Cervical cancer | Cancer | Human papillomavirus | Mutation | Index Medicus
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13. Full Text Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in NOTCH1
by Nishant Agrawal and Mitchell J. Frederick and Curtis R. Pickering and Chetan Bettegowda and Kyle Chang and Ryan J. Li and Carole Fakhry and Tong-Xin Xie and Jiexin Zhang and Jing Wang and Nianxiang Zhang and Adel K. El-Naggar and Samar A. Jasser and John N. Weinstein and Lisa Treviño and Jennifer A. Drummond and Donna M. Muzny and Yuanqing Wu and Laura D. Wood and Ralph H. Hruban and William H. Westra and Wayne M. Koch and Joseph A. Califano and Richard A. Gibbs and David Sidransky and Bert Vogelstein and Victor E. Velculescu and Nickolas Papadopoulos and David A. Wheeler and Kenneth W. Kinzler and Jeffrey N. Myers
Science, ISSN 0036-8075, 8/2011, Volume 333, Issue 6046, pp. 1154 - 1157
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide. To explore the genetic origins of this cancer, we used whole-exome... 
Head | REPORTS | Medical genetics | Nonsense | Tumor suppressor genes | Genetic mutation | Sequencing | Human genetics | Oncogenes | Tumors | Cancer | PROGNOSTIC IMPLICATIONS | GENE | PATHWAY | STATISTICS | MULTIDISCIPLINARY SCIENCES | OROPHARYNGEAL CANCER | TUMOR-SUPPRESSOR | HUMAN-PAPILLOMAVIRUS | LEUKEMIA | P53 | F-Box-WD Repeat-Containing Protein 7 | Head and Neck Neoplasms - virology | Oligonucleotide Array Sequence Analysis | Exons | Humans | Carcinoma - virology | Receptor, Notch1 - chemistry | Neoplasms, Squamous Cell - virology | Mutation, Missense | INDEL Mutation | Genes, p53 | Squamous Cell Carcinoma of Head and Neck | Neoplasms, Squamous Cell - drug therapy | Cell Cycle Proteins - genetics |