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kinases (36) 36
precursor t-cell lymphoblastic leukemia-lymphoma - genetics (36) 36
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acute lymphoblastic-leukemia (35) 35
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STEM CELLS, ISSN 1066-5099, 09/2017, Volume 35, Issue 9, pp. 2027 - 2036
The cancer stem cell (CSC) paradigm suggests that tumors are organized hierarchically. Chugai previously established an LGR5+ human colorectal cancer (CRC)... 
Cancer stem cells | F‐box/WD repeat‐containing protein 7 | c‐Myc | Colorectal cancer | Chemoresistance | F-box/WD repeat-containing protein 7 | c-Myc | INITIATING CELLS | HEMATOPOIETIC-CELL | COLON | IDENTIFICATION | CHROMOSOMAL INSTABILITY | CELL & TISSUE ENGINEERING | CELL BIOLOGY | GENE | ONCOLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | DIFFERENTIATION | LEUKEMIA | HEMATOLOGY | TUMOR-GROWTH | EXPRESSION | Receptors, G-Protein-Coupled - metabolism | Neoplastic Stem Cells - drug effects | Colorectal Neoplasms - genetics | Humans | Antineoplastic Agents - therapeutic use | F-Box-WD Repeat-Containing Protein 7 - genetics | Proteolysis - drug effects | Neoplastic Stem Cells - metabolism | Colorectal Neoplasms - drug therapy | Neoplastic Stem Cells - pathology | Liver Neoplasms - pathology | Antineoplastic Agents - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Liver Neoplasms - secondary | Proto-Oncogene Proteins c-myc - metabolism | Down-Regulation - genetics | Up-Regulation - drug effects | Drug Resistance, Neoplasm - genetics | Animals | Cell Line, Tumor | Mice | Receptors, G-Protein-Coupled - genetics | Colorectal Neoplasms - pathology | F-Box-WD Repeat-Containing Protein 7 - metabolism | Drug Resistance, Neoplasm - drug effects | Cell death | Liver | Colorectal carcinoma | c-Myc protein | Myc protein | Drug resistance | Cdc4 protein | Metastases | Anticancer properties | Antitumor agents | Cell cycle | siRNA | Tumor cell lines | Irinotecan | Chemotherapy | Molecular modelling | Overexpression | Ribonucleic acids | Stem cells | Regulatory mechanisms (biology) | Sensitivity enhancement | Differentiation | Tumors | Cancer
Journal Article
European Urology, ISSN 0302-2838, 2015, Volume 70, Issue 3, pp. 516 - 521
Journal Article
Cancer, ISSN 0008-543X, 01/2018, Volume 124, Issue 1, pp. 65 - 73
BACKGROUND Uterine carcinosarcomas (UCSs) are a rare but clinically aggressive form of cancer. They are biphasic tumors consisting of both epithelial and... 
endometrial cancer | carcinosarcoma | mutation | endometrial carcinoma | exome | uterine cancer | SUPPRESSOR | UTERUS | MISMATCH REPAIR | PREGNANCY | MIXED MULLERIAN TUMORS | ONCOLOGY | DNA | GENES | MUTATIONS | EXPRESSION | Uterine Neoplasms - genetics | Carcinoma, Endometrioid - genetics | Microsatellite Instability | Class I Phosphatidylinositol 3-Kinases - genetics | Hepatocyte Nuclear Factor 3-beta - genetics | Humans | Protein Phosphatase 2 - genetics | Mi-2 Nucleosome Remodeling and Deacetylase Complex - genetics | Autoantigens - genetics | Sequence Analysis, DNA | Tumor Suppressor Protein p53 - genetics | Neoplasms, Cystic, Mucinous, and Serous - genetics | F-Box-WD Repeat-Containing Protein 7 - genetics | Endometrial Neoplasms - genetics | Polymerase Chain Reaction | Cell Line, Tumor | Carcinoma - genetics | Female | Carcinosarcoma - genetics | Mutation | Adenocarcinoma, Clear Cell - genetics | Transcription factors | Care and treatment | Usage | Genetic aspects | Research | Nucleotide sequencing | Uterine cancer | DNA sequencing | Carcinoma | Identification methods | p53 Protein | Genes | Frameshift mutation | Immunoblotting | Phosphatidylinositol 4,5-diphosphate | Kinases | Cdc4 protein | Gene sequencing | DNA helicase | Proteins | Metaplasia | Uterus | Etiology | Forkhead protein | Protein phosphatase | Catalysis | Endometrium | Deoxyribonucleic acid--DNA | Cancer | Tumors | Endometrial cancer
Journal Article
Cancer, ISSN 0008-543X, 01/2018, Volume 124, Issue 1, pp. 84 - 94
BACKGROUND Human immunodeficiency virus–infected individuals (HIVIIs) have a higher incidence of head and neck squamous cell carcinoma (HNSCC), and clinical... 
human papillomavirus (HPV) | mutation | head and neck cancer | human immunodeficiency virus (HIV) | TP53 gene | UNITED-STATES | HIV/AIDS | POPULATION | HUMAN-PAPILLOMAVIRUS | HIV PATIENTS | P53 | P53-MEDIATED APOPTOSIS | BREAST-CANCER | CIGARETTE-SMOKING | ONCOLOGY | INFECTION | Receptors, Transforming Growth Factor beta - genetics | Class I Phosphatidylinositol 3-Kinases - genetics | Proto-Oncogene Proteins p21(ras) - genetics | Carcinoma, Squamous Cell - genetics | Humans | Middle Aged | ErbB Receptors - genetics | Male | Receptor, Notch2 - genetics | Case-Control Studies | Papillomaviridae - genetics | Tumor Suppressor Protein p53 - genetics | Caspase 8 - genetics | Kelch-Like ECH-Associated Protein 1 - genetics | F-Box-WD Repeat-Containing Protein 7 - genetics | Squamous Cell Carcinoma of Head and Neck | In Situ Hybridization | Receptor, Transforming Growth Factor-beta Type II | Tumor Suppressor Proteins - genetics | Adult | Female | NF-E2-Related Factor 2 - genetics | Cadherins - genetics | Nuclear Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | Papillomavirus Infections - complications | Protein-Serine-Threonine Kinases - genetics | Transcription Factors - genetics | Cyclin-Dependent Kinase Inhibitor p18 - genetics | Cyclin D1 - genetics | Carcinoma, Squamous Cell - complications | HIV Infections - complications | HLA-A Antigens - genetics | Head and Neck Neoplasms - complications | Head and Neck Neoplasms - genetics | LIM Domain Proteins - genetics | Aged | Receptor, Notch1 - genetics | Multiplexing | Pathogenesis | Exons | p53 Protein | Genes | Viruses | Genomes | Infections | Cdc4 protein | Gene sequencing | Biological effects | Human papillomavirus | Human immunodeficiency virus--HIV | Deoxyribonucleic acid--DNA | Head | Squamous cell carcinoma | Nucleotide sequence | Epidermal growth factor receptors | Data processing | Patients | Polymerase chain reaction | Head and neck cancer | Histocompatibility antigen HLA | Mutation | Tumors | DNA sequencing | Cancer
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 09/2017, Volume 16, Issue 9, pp. 1979 - 1988
Journal Article
Nature Communications, ISSN 2041-1723, 07/2017, Volume 8, Issue 1, p. 16003
Journal Article
The American Journal of Surgical Pathology, ISSN 0147-5185, 01/2018, Volume 42, Issue 1, pp. 18 - 27
Journal Article
Molecular Cancer, ISSN 1476-4598, 08/2018, Volume 17, Issue 1, pp. 115 - 19
Journal Article
Gynecologic Oncology, ISSN 0090-8258, 09/2018, Volume 150, Issue 3, pp. 552 - 561
Vulvar squamous cell carcinoma (VSCC) constitutes over 90% of vulvar cancer. Its pathogenesis can follow two different pathways; high risk human papillomavirus... 
mTOR | Vulvar cancer | NGS | CDKN2A | TP53 | HPV | CLASSIFICATION | HUMAN-PAPILLOMAVIRUS | INTRAEPITHELIAL NEOPLASIA | LESIONS | OBSTETRICS & GYNECOLOGY | WOMEN | ONCOLOGY | VSCC | SQUAMOUS-CELL CARCINOMA | INFECTION | Class I Phosphatidylinositol 3-Kinases - genetics | Antibiotics, Antineoplastic - pharmacology | TOR Serine-Threonine Kinases - metabolism | Proto-Oncogene Proteins p21(ras) - genetics | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - virology | Humans | Middle Aged | Proto-Oncogene Proteins c-akt - genetics | Tumor Suppressor Protein p53 - genetics | fms-Like Tyrosine Kinase 3 - genetics | F-Box-WD Repeat-Containing Protein 7 - genetics | Smad4 Protein - genetics | DNA Mutational Analysis | Vulvar Neoplasms - metabolism | Aged, 80 and over | Adult | Female | Antineoplastic Agents - pharmacology | DNA, Neoplasm - analysis | Proto-Oncogene Proteins c-akt - metabolism | Phosphatidylinositol 3-Kinase - metabolism | Cell Survival - drug effects | GTP-Binding Protein alpha Subunits, Gq-G11 - genetics | PTEN Phosphohydrolase - genetics | Receptor, Fibroblast Growth Factor, Type 3 - genetics | Papillomavirus Infections - complications | Everolimus - pharmacology | Protein-Serine-Threonine Kinases - genetics | Morpholines - pharmacology | Vulvar Neoplasms - virology | Signal Transduction - genetics | Sirolimus - pharmacology | Disease-Free Survival | Cyclin-Dependent Kinase Inhibitor p18 - genetics | Signal Transduction - drug effects | Vulvar Neoplasms - genetics | Janus Kinase 3 - genetics | Cell Line, Tumor | Papillomaviridae | Aged | High-Throughput Nucleotide Sequencing | Protein Kinase Inhibitors - pharmacology | Mutation
Journal Article
Journal Article
Structure (London, England : 1993), 01/2018, Volume 26, Issue 1, p. 28
Journal Article
Journal Article
Molecular Genetics and Genomics, ISSN 1617-4615, 2019, Volume 294, Issue 3, pp. 573 - 582
Journal Article