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Molecular Pharmacology, ISSN 0026-895X, 11/2006, Volume 70, Issue 5, pp. 1469 - 1480
Journal Article
JOURNAL OF CELLULAR PHYSIOLOGY, ISSN 0021-9541, 02/2012, Volume 227, Issue 2, pp. 514 - 524
The hypoxia-inducible factor-1 (HIF-1) is an oxygen-regulated transcriptional activator playing a pivotal role in mammalian physiology and disease... 
HYPOXIA-INDUCIBLE FACTOR | FACTOR 1-ALPHA HIF-1-ALPHA | TUMOR-NECROSIS-FACTOR | PHYSIOLOGY | MICROPHTHALMIA TRANSCRIPTION FACTOR | HEPATOCYTE GROWTH-FACTOR | FACTOR EXPRESSION | ANGIOTENSIN-II | NF-KAPPA-B | FACTOR-1-ALPHA EXPRESSION | MELANOCYTE DEVELOPMENT | CELL BIOLOGY
Journal Article
JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, 08/2000, Volume 275, Issue 33, pp. 25130 - 25138
During hypoxia, hypoxia-inducible factor-1 alpha (HIF-1 alpha) is required for induction of a variety of genes including erythropoietin and vascular... 
FACTOR 1-ALPHA HIF-1-ALPHA | CYTOCHROME-C-OXIDASE | PARACOCCUS-DENITRIFICANS | SIGNALING PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | HYDROGEN-PEROXIDE | FACTOR-I | CELLULAR RESPIRATION | TRANSCRIPTION FACTOR | ENDOTHELIAL GROWTH-FACTOR | DNA-BINDING ACTIVITY
Journal Article
Molecular Biology of the Cell, ISSN 1059-1524, 01/2008, Volume 19, Issue 1, pp. 86 - 94
Hypoxia-inducible factor-1 (HIF-1) is a decisive element for the transcriptional regulation of many genes induced under low oxygen conditions. Under normal... 
FACTOR 1-ALPHA HIF-1-ALPHA | TRANSCRIPTIONAL ACTIVATION | HUMAN ERYTHROPOIETIN GENE | PROLYL HYDROXYLATION | TUMOR-SUPPRESSOR PROTEIN | SMOOTH-MUSCLE-CELLS | ANGIOTENSIN-II | FACTOR-I | HIF-ALPHA | MITOCHONDRIAL COMPLEX-III | CELL BIOLOGY
Journal Article
The American Journal of Pathology, ISSN 0002-9440, 2000, Volume 157, Issue 2, pp. 411 - 421
The cellular response to hypoxia includes the hypoxia-inducible factor-1 (HIF-1)-induced transcription of genes involved in diverse processes such as... 
FACTOR 1-ALPHA HIF-1-ALPHA | CELLS | BREAST-CARCINOMA | SOLID TUMORS | GENE-EXPRESSION | VEGF EXPRESSION | FACTOR-I | PATHOLOGY | TRANSCRIPTION FACTOR | ENDOTHELIAL GROWTH-FACTOR | PAS DOMAIN PROTEIN-1 | Regular
Journal Article
Cancer Research, ISSN 0008-5472, 02/2006, Volume 66, Issue 3, pp. 1684 - 1693
Hypoxia-inducible factor-1 alpha. (HIF-1 alpha) is a transcription factor that directly transactivates genes important for the growth and metabolism of solid... 
FACTOR 1-ALPHA HIF-1-ALPHA | HIF-1 | ANGIOGENESIS | ONCOLOGY | TRANSCRIPTION | GENE-EXPRESSION | FACTOR EXPRESSION | FACTOR-I | FACTOR (HIF)-1-ALPHA | TUMOR-GROWTH | ENDOTHELIAL GROWTH-FACTOR
Journal Article
International Journal of Cancer, ISSN 0020-7136, 04/2007, Volume 120, Issue 7, pp. 1451 - 1458
Hypoxia stabilizes HIF‐1α (Hypoxia Inducible Factor‐1α), which then triggers the expression of several genes involved in many aspects of cancer progression,... 
breast cancer | HIF‐1α | immunohistochemistry | prognosis | predictive factor | CA IX | Immunohistochemistry | Breast cancer | HIF-1α | Prognosis | Predictive factor | CARBONIC-ANHYDRASE-IX | HIF-1 alpha | PROTEIN | MARKER | CA 1X | CANCER | FACTOR 1-ALPHA HIF-1-ALPHA | OVEREXPRESSION | ONCOLOGY | HYPOXIA-INDUCIBLE FACTOR-1-ALPHA | HIF-ALPHA | EXPRESSION | UBIQUITIN-PROTEASOME PATHWAY
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 05/2004, Volume 3, Issue 5, pp. 647 - 654
The hypoxia inducible factor 1 (HIF-1) is a heterodimeric transcription factor that is an important regulator of the growing tumor's response to hypoxia. HIF-1... 
SIGNAL-TRANSDUCTION | FACTOR 1-ALPHA HIF-1-ALPHA | LUNG-CANCER | DNA-BINDING | ONCOLOGY | PROTEIN-KINASE | GENE-EXPRESSION | CELL-PROLIFERATION | TUMOR ANGIOGENESIS | ENDOTHELIAL GROWTH-FACTOR | BRAIN-TUMORS
Journal Article
GENES & DEVELOPMENT, ISSN 0890-9369, 05/2007, Volume 21, Issue 9, pp. 1037 - 1049
Mammalian cells are believed to have a cell-intrinsic ability to increase glucose metabolism in response to hypoxia. Here we show that the ability of... 
LACTATE-DEHYDROGENASE | hypoxia | HYPOXIA-INDUCIBLE FACTOR | A EXPRESSION | HIF-1 alpha | cell survival | FACTOR EXPRESSION | DEVELOPMENTAL BIOLOGY | CELL-GROWTH | TUMOR ANGIOGENESIS | growth factor signaling | CELL BIOLOGY | FACTOR 1-ALPHA HIF-1-ALPHA | GLUCOSE-METABOLISM | RESPONSE ELEMENTS | GENETICS & HEREDITY | glucose metabolism | HIF-ALPHA | Research Paper | HIF-1α
Journal Article