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Cancer Science, ISSN 1347-9032, 12/2016, Volume 107, Issue 12, pp. 1800 - 1805
We proposed to compare the outcomes of first‐line epidermal growth factor receptor–tyrosine kinase inhibitor ( EGFR ‐ TKI ) alone with EGFR ‐ TKI plus... 
EGFR mutation | radiotherapy | prognosis | Brain metastasis | lung adenocarcinoma | CANCER PATIENTS | GEFITINIB | PHASE-II | RADIATION-THERAPY | TKI | ONCOLOGY | MUTATIONS | ERLOTINIB | Adenocarcinoma - pathology | Adenocarcinoma of Lung | Lung Neoplasms - mortality | Humans | Middle Aged | ErbB Receptors - genetics | Lung Neoplasms - pathology | Male | Protein Kinase Inhibitors - adverse effects | Brain Neoplasms - secondary | Adult | Female | Adenocarcinoma - genetics | Retrospective Studies | Brain Neoplasms - mortality | Lung Neoplasms - genetics | ErbB Receptors - antagonists & inhibitors | Proportional Hazards Models | Treatment Outcome | Combined Modality Therapy | Disease Progression | Protein Kinase Inhibitors - administration & dosage | Protein Kinase Inhibitors - therapeutic use | Brain Neoplasms - therapy | Radiotherapy - methods | Aged | Mutation | Neoplasm Staging | Adenocarcinoma - mortality | Adenocarcinoma | Tyrosine | Brain | Medical research | Care and treatment | Epidermal growth factor | Lung cancer | Brain tumors | Medicine, Experimental | Phenols | Metastasis | Radiotherapy | Brain cancer | Lung | Oncology | Nervous system | Cancer therapies | Metastases | Neurotoxicity | Clonal deletion | Protein-tyrosine kinase | Medical imaging | Epidermal growth factor receptors | Radiation therapy | Survival | Patients | Disease control | Studies | Survival analysis | Medical prognosis | Response rates | Index Medicus | Original
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2014, Volume 289, Issue 30, pp. 20813 - 20823
Journal Article
Cancer Research, ISSN 0008-5472, 08/2004, Volume 64, Issue 15, pp. 5355 - 5362
Molecular inhibition of epidermal growth factor receptor (EGFR/HER1) signaling is under active investigation as a promising cancer treatment strategy. We... 
PATHWAYS | APOPTOSIS | HEAD | THERAPY | CANCER CELLS | ONCOLOGY | RESISTANCE | TUMOR-CELLS | PROLIFERATION | TARCEVA | BREAST | Erlotinib Hydrochloride | Lung Neoplasms - drug therapy | Prostatic Neoplasms - metabolism | Apoptosis - drug effects | Carcinoma, Squamous Cell - metabolism | Humans | Lung Neoplasms - metabolism | Immunoblotting | Male | Transplantation, Heterologous | Head and Neck Neoplasms - metabolism | Antibodies, Monoclonal, Humanized | Receptor, Epidermal Growth Factor - metabolism | Flow Cytometry | Female | Quinazolines - administration & dosage | Phosphorylation - drug effects | Tumor Cells, Cultured | Cetuximab | Prostatic Neoplasms - drug therapy | Protein-Serine-Threonine Kinases - metabolism | Proto-Oncogene Proteins - metabolism | Carcinoma, Non-Small-Cell Lung - metabolism | Enzyme Inhibitors - pharmacology | Head and Neck Neoplasms - drug therapy | Cell Division - drug effects | Proto-Oncogene Proteins c-akt | Animals | Carcinoma, Squamous Cell - drug therapy | Antibodies, Monoclonal - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Mice | Carcinoma, Non-Small-Cell Lung - drug therapy | Proliferating Cell Nuclear Antigen - metabolism | Mitogen-Activated Protein Kinases - metabolism | Protein-Tyrosine Kinases - antagonists & inhibitors | Index Medicus
Journal Article
Science Translational Medicine, ISSN 1946-6234, 12/2013, Volume 5, Issue 216, pp. 216ra177 - 216ra177
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 05/2009, Volume 15, Issue 10, pp. 3484 - 3494
Purpose: The epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI) gefitinib and erlotinib benefit some non–small cell lung cancer (NSCLC)... 
resistance | Non-small cell lung cancer | EGFR inhibitors | CELL LUNG-CANCER | GEFITINIB | THERAPY | ONCOLOGY | HUMAN PANCREATIC-CARCINOMA | ACQUIRED-RESISTANCE | TYROSINE KINASE INHIBITOR | PHASE-II | MONOCLONAL-ANTIBODY | MUTATIONS | ANTITUMOR-ACTIVITY | Erlotinib Hydrochloride | Lung Neoplasms - drug therapy | NIH 3T3 Cells | Receptor, Epidermal Growth Factor - genetics | Humans | Lung Neoplasms - metabolism | Drug Resistance, Neoplasm | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Bevacizumab | Antibodies, Monoclonal, Humanized | Receptor, Epidermal Growth Factor - metabolism | Receptors, Vascular Endothelial Growth Factor - metabolism | Transfection | Piperidines - pharmacology | Time Factors | Receptors, Vascular Endothelial Growth Factor - antagonists & inhibitors | Quinazolines - administration & dosage | Receptors, Vascular Endothelial Growth Factor - genetics | Carcinoma, Non-Small-Cell Lung - pathology | Piperidines - administration & dosage | Antibodies, Monoclonal - pharmacology | Carcinoma, Non-Small-Cell Lung - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Xenograft Model Antitumor Assays | Animals | Tumor Burden - drug effects | Antibodies, Monoclonal - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Mice, Nude | Cell Line, Tumor | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Cell Proliferation - drug effects | Mice | Carcinoma, Non-Small-Cell Lung - drug therapy | Mutation | Quinazolines - pharmacology | Index Medicus
Journal Article
Expert Opinion on Drug Delivery, ISSN 1742-5247, 04/2019, Volume 16, Issue 4, pp. 441 - 451
Introduction: Malignant mesothelioma (MM) is an aggressive malignancy arising from the mesothelial cells lining the pleura and other serosal membranes. It is... 
targeted therapies | malignant mesothelioma | EGFR overexpression | Epidermal growth factor receptor (EGFR) | TYROSINE KINASE DOMAIN | PHASE-III | MALIGNANT PLEURAL MESOTHELIOMA | ANTIBODY | OPEN-LABEL | CELL LUNG-CANCER | PROTEIN EXPRESSION | EGFR EXPRESSION | PHARMACOLOGY & PHARMACY | GENE COPY NUMBER | ACTIVATING MUTATIONS
Journal Article
Annals of Oncology, ISSN 0923-7534, 08/2013, Volume 24, Issue 8, pp. 2080 - 2087
Journal Article
Journal of Thoracic Oncology, ISSN 1556-0864, 01/2015, Volume 10, Issue 1, pp. 156 - 163
Journal Article