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Frontiers in Oncology, ISSN 2234-943X, 2018, Volume 8, pp. 574 - 574
Hypoxia-inducible transcription factors (HIFs) drive angiogenesis and cancer cell growth, contributing to an aggressive tumor phenotype. HIF-alpha protein... 
HIF-1 | HIF-2 | Clear cell renal cell carcinoma | VHL | Papillary renal cell carcinoma | Vitamin C | VITAMIN-C | SURVIVAL | clear cell renal cell carcinoma | papillary renal cell carcinoma | ACID | vitamin C | RISK | STRATEGIES | CLEAR-CELL | ONCOLOGY | GROWTH | FACTOR-I-ALPHA | KIDNEY CANCER
Journal Article
Journal Article
WORLD JOURNAL OF SURGICAL ONCOLOGY, ISSN 1477-7819, 07/2018, Volume 16
Background: HIF-1 alpha and CAIX proteins are commonly expressed under hypoxic conditions, but other regulatory factors have been described as well. Pancreatic... 
SURGERY | CARBONIC-ANHYDRASE-IX | HIF-1 alpha | METASTASIS | PREDICTOR | CANCER CELLS | FACTOR 1-ALPHA EXPRESSION | Pancreatic ductal adenocarcinoma | TUMOR ANGIOGENESIS | OVEREXPRESSION | ONCOLOGY | HYPOXIA-INDUCIBLE FACTOR-1-ALPHA | Carbonic anhydrase 9 | HIF-1-ALPHA | FACTOR-I ALPHA
Journal Article
Cell Research, ISSN 1001-0602, 06/2006, Volume 16, Issue 6, pp. 548 - 558
The role of the hypoxia-inducible factor (HIF) subunits 1 alpha and 2 alpha in response to hypoxia. is well established in lung epithelial cells, whereas... 
Hypoxia | Alveolar epithelial type II cells | Gene expression | Hypoxia inducible factor | in vitro | hypoxia | ACTIVATION | STABILIZATION | hypoxia inducible factor | HEME OXYGENASE-1 GENE | PAS DOMAIN PROTEIN-1 | CELL BIOLOGY | FACTOR 1-ALPHA | alveolar epithelial type II cells | MESSENGER-RNA | PATHWAY | ENDOTHELIAL-CELLS | FACTOR-I-ALPHA | TRANSCRIPTION FACTOR | gene expression
Journal Article
Journal Article
JOURNAL OF LEUKOCYTE BIOLOGY, ISSN 0741-5400, 09/2009, Volume 86, Issue 3, pp. 681 - 689
Adenosine A2AR and TLR agonists synergize to induce an "angiogenic switch" in macrophages, down-regulating TNF-alpha and up-regulating VEGF expression. This... 
HYPOXIA-INDUCIBLE FACTOR | HIF-1-ALPHA PROTEIN | TNF-alpha | transcription factors | VEGF | ARNT TRANSCRIPTION FACTOR | IMMUNOLOGY | CELL BIOLOGY | FACTOR 1-ALPHA | alternative activation | inflammation | SYNERGISTIC UP-REGULATION | GENE-EXPRESSION | NITRIC-OXIDE | HEMATOLOGY | NF-KAPPA-B | endotoxin | ENDOTHELIAL GROWTH-FACTOR | FACTOR-I ALPHA
Journal Article
Journal Article
Translational Cancer Research, ISSN 2218-676X, 06/2018, Volume 7, Issue 3, pp. 561 - 570
Background: The study was aimed to explore the expression of hypoxia-inducible factor-1 alpha (HIF-1 alpha) and p53 protein, as well as their correlation with... 
HIF-1α | Prognosis | Non-small cell lung carcinoma (NSCLC) | P53 | APOPTOSIS | HIF-1 alpha | TRANSCRIPTION | non-small cell lung carcinoma (NSCLC) | prognosis | CANCER | RADIATION | p53 | GROWTH-FACTOR RECEPTOR | ONCOLOGY | POOR-PROGNOSIS | RESISTANCE | HIF-1-ALPHA | ASSOCIATION | FACTOR-I ALPHA
Journal Article
JOURNAL OF BUON, ISSN 1107-0625, 05/2015, Volume 20, Issue 3, pp. 680 - 689
Colorectal cancer (CRC) is the third most common cancer worldwide and despite the abundance of molecular pathways and markers continually being reported, the... 
TARGETED THERAPY | ENDOTHELIAL-GROWTH-FACTOR | angiogenesis | CLINICOPATHOLOGICAL SIGNIFICANCE | HIP-1a | DOWN-REGULATION | FACTOR EXPRESSION | colorectal carcinoma | prognosis | COLON-CANCER | ONCOLOGY | HYPOXIA-INDUCIBLE FACTOR-1-ALPHA | FACTOR-I-ALPHA | immunohistochemistry | ADVANCED RECTAL-CANCER | HIF-1-ALPHA EXPRESSION
Journal Article
ARTHRITIS RESEARCH & THERAPY, ISSN 1478-6354, 2008, Volume 10, Issue 5, pp. R111 - R111
Introduction Chondrocytes have to withstand considerable hypoxic conditions within the avascular articular cartilage. The present study investigated the... 
OSTEOARTHRITIC CHONDROCYTES | CELLS | TRANSCRIPTIONAL ACTIVATION | FACTOR-I-ALPHA | HIF-1-ALPHA | 2-METHOXYESTRADIOL | DIFFERENTIATION | RHEUMATOLOGY | MOUSE KNEE | TUMOR-GROWTH | EXPRESSION
Journal Article