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HUMAN GENE THERAPY, ISSN 1043-0342, 10/2011, Volume 22, Issue 10, pp. 1239 - 1247
Recombinant adeno-associated virus (rAAV) vectors offer promise for the gene therapy of alpha(1)-antitrypsin (AAT) deficiency. in our prior trial, an rAAV... 
MEDICINE, RESEARCH & EXPERIMENTAL | TRANSDUCTION | VIRUS TYPE-1 | DELIVERY | SKELETAL-MUSCLE | AAT VECTOR | THERAPY | SEROTYPE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | FACTOR-IX | GENETICS & HEREDITY | GENE-TRANSFER | HUMAN ALPHA-1-ANTITRYPSIN
Journal Article
Blood, ISSN 0006-4971, 07/2016, Volume 128, Issue 2, pp. 156 - 157
In this issue of Blood, Cooley et al challenge the assumption that the plasma halflife of factor IX (FIX) is a surrogate marker for the duration of hemostatic... 
FUSION PROTEIN | IDENTIFICATION | HEMATOLOGY | HEMOPHILIA-B | COAGULATION-FACTOR-IX
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 11/2014, Volume 371, Issue 21, pp. 1994 - 2004
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 08/2017, Volume 377, Issue 9, pp. 819 - 828
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 12/2017, Volume 377, Issue 23, pp. 2215 - 2227
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 12/2011, Volume 365, Issue 25, pp. 2357 - 2365
Journal Article
Blood, ISSN 0006-4971, 08/2013, Volume 122, Issue 6, pp. 863 - 871
Journal Article
Toxicon, ISSN 0041-0101, 06/2012, Volume 59, Issue 7-8, pp. 718 - 723
Anticoagulation factor I (ACF I), a snake C-type lectin (snaclec) from the venom of Agkistrodon acutus binds specifically with activated factor X (FXa) in a Ca... 
Snaclec | Agkistrodon acutuss | Factor IX | ACF I
Journal Article
Journal of Blood Medicine, ISSN 1179-2736, 04/2016, Volume 2016, Issue Issue 1, pp. 27 - 38
Moniba Nazeef,1,2 John P Sheehan1,2 1Department of Medicine, Division of Hematology/Oncology, 2UW Carbone Cancer Center, University of Wisconsin School of... 
Hemophilia B Factor IX Therapeutics
Journal Article
Drug Design, Development and Therapy, ISSN 1177-8881, 2014, Volume 8, pp. 365 - 371
Journal Article
Circulation, ISSN 0009-7322, 09/2013, Volume 128, Issue 11, pp. 1234 - 1243
BACKGROUND—Patients experiencing major bleeding while taking vitamin K antagonists require rapid vitamin K antagonist reversal. We performed a prospective... 
CARDIAC & CARDIOVASCULAR SYSTEMS | ORAL ANTICOAGULANT REVERSAL | CLINICAL-TRIAL | RECOMBINANT FACTOR-VIII | vitamin K antagonist | prothrombin complex concentrates | PREVIOUSLY UNTREATED PATIENTS | INTRACRANIAL HEMORRHAGE | THERAPY | WARFARIN | TRANSFUSION | HEMOPHILIA-A | anticoagulants | PERIPHERAL VASCULAR DISEASE | plasma | FRESH-FROZEN PLASMA | hemorrhage | Single-Blind Method | Plasma | Prospective Studies | Thromboembolism - chemically induced | Factor IX - therapeutic use | Humans | Middle Aged | Male | Factor IX - adverse effects | Hemorrhage - prevention & control | Vitamin K - antagonists & inhibitors | Thromboembolism - prevention & control | Aged, 80 and over | Adult | Factor X - therapeutic use | Female | Factor X - adverse effects | Factor VII - adverse effects | Factor VII - therapeutic use | Emergencies | Anticoagulants - therapeutic use | Treatment Outcome | Prothrombin - therapeutic use | Anticoagulants - adverse effects | Prothrombin - adverse effects | Hemostatics - adverse effects | International Normalized Ratio | Hemorrhage - drug therapy | Blood Coagulation Factors - adverse effects | Anticoagulants - pharmacology | Blood Coagulation Factors - therapeutic use | Aged | Hemorrhage - chemically induced | Hemostatics - therapeutic use | Drug Combinations | Antidotes - therapeutic use | Antagonists (Biochemistry) | Usage | Care and treatment | Blood coagulation factors | Health aspects | Hemorrhage | Index Medicus | Abridged Index Medicus
Journal Article
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, ISSN 1538-7933, 04/2013, Volume 11, Issue 4, pp. 670 - 678
Background N8-GP is a recombinant factorVIII (FVIII) with a site-directed glycoPEGylation for the purpose of half-life prolongation. Objectives To evaluate the... 
POPULATION | first-in-human | VIII-C INHIBITORS | BETHESDA ASSAY | rFVIII | PROPHYLACTIC TREATMENT | PEG | THERAPEUTIC PROTEINS | FACTOR-IX | PERIPHERAL VASCULAR DISEASE | EXPERIENCE | hemophiliaA | NIJMEGEN MODIFICATION | HEMATOLOGY | PEGYLATION | half-life prolongation
Journal Article
2010, 2nd ed., ISBN 1405169141, xii, 464
The Textbook of Hemophilia has become a definitive resource for all those managing hemophilia patients. It covers all the common and rare bleeding disorders,... 
physiopathology | Factor IX | Hemophilia | Factor VIII | physiology | Hemophilia B | Coagulation Protein Disorders | Hemophilia A | Blood coagulation disorders
Book