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index medicus (584) 584
humans (510) 510
hematology (230) 230
factor ixa (205) 205
biochemistry & molecular biology (185) 185
animals (172) 172
factor-ixa (171) 171
factor ixa - metabolism (155) 155
peripheral vascular disease (142) 142
kinetics (141) 141
thrombin (137) 137
blood-coagulation (116) 116
binding sites (99) 99
protein binding (94) 94
blood coagulation (89) 89
models, molecular (86) 86
amino acid sequence (85) 85
factor viii - metabolism (84) 84
coagulation (82) 82
factor viii (79) 79
male (78) 78
molecular sequence data (76) 76
factor x - metabolism (74) 74
factor xa (73) 73
anticoagulants (72) 72
abridged index medicus (70) 70
factor ixa - chemistry (68) 68
protein conformation (68) 68
binding-site (67) 67
tissue factor (67) 67
von-willebrand-factor (66) 66
factor viiia - metabolism (65) 65
thrombin - metabolism (65) 65
binding (61) 61
factor ixa - antagonists & inhibitors (61) 61
factor xa - metabolism (61) 61
blood coagulation - drug effects (59) 59
factor-x (59) 59
activation (58) 58
factor viii - chemistry (57) 57
mutation (57) 57
anticoagulants - pharmacology (55) 55
crystal-structure (54) 54
light-chain (54) 54
factor-xa (52) 52
heparin (52) 52
structure-activity relationship (52) 52
hemophilia (51) 51
activated protein-c (50) 50
porcine factor-viii (50) 50
recombinant proteins - metabolism (48) 48
protein structure, tertiary (47) 47
factor ix - metabolism (46) 46
female (46) 46
recombinant proteins - chemistry (45) 45
analysis (43) 43
coagulation-factor-viii (42) 42
proteins (42) 42
article (41) 41
factor viii - genetics (41) 41
thrombosis (40) 40
factor viii - immunology (39) 39
factor viiia - chemistry (39) 39
research (38) 38
active-site (37) 37
blood coagulation tests (37) 37
hemophilia-a (37) 37
thrombin generation (37) 37
adult (36) 36
factor ix (36) 36
cysteine endopeptidases - metabolism (35) 35
enzyme activation (35) 35
vonwillebrand-factor (35) 35
thromboplastin - metabolism (34) 34
dose-response relationship, drug (33) 33
factor ixa - genetics (32) 32
factor viia - metabolism (32) 32
mice (32) 32
partial thromboplastin time (32) 32
biophysics (31) 31
blood coagulation factor viii (31) 31
cattle (31) 31
phospholipids - metabolism (31) 31
blood platelets - metabolism (30) 30
calcium - metabolism (30) 30
catalysis (30) 30
heparin - pharmacology (30) 30
drug design (29) 29
factor-viii (29) 29
hemostasis (29) 29
middle aged (29) 29
mutagenesis, site-directed (29) 29
anticoagulant (28) 28
catalytic domain (28) 28
cofactor activity (28) 28
factor ix - genetics (28) 28
procoagulant activity (28) 28
time factors (28) 28
a1/a3-c1-c2 dimer (27) 27
anticoagulants - therapeutic use (27) 27
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Nature Medicine, ISSN 1078-8956, 10/2012, Volume 18, Issue 10, pp. 1570 - 1574
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2013, Volume 8, Issue 2, pp. e57479 - e57479
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2016, Volume 291, Issue 9, pp. 4671 - 4683
Journal Article
THROMBOSIS AND HAEMOSTASIS, ISSN 0340-6245, 07/2017, Volume 117, Issue 7, pp. 1348 - 1357
Emicizumab, a humanised bispecific antibody recognising factors (F) IX/IXa and X/Xa, can accelerate FIXa-catalysed FX activation by bridging FIXa and FX in a... 
MANAGEMENT | drug design | FACTOR-VIII | LIGHT-CHAIN | MONOCLONAL-ANTIBODY | ACE910 | Coagulation factors | FACTOR IXA | haemophilia therapy | BINDING-SITE | PERIPHERAL VASCULAR DISEASE | FACTOR-X | HEMOPHILIA-A MODEL | HEMATOLOGY | factor VIII | SUBUNIT
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 11/2017, Volume 38, Issue 1, pp. 266 - 274
Journal Article
Circulation, ISSN 0009-7322, 12/2006, Volume 114, Issue 23, pp. 2490 - 2497
Journal Article
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 06/2019, Volume 119, Issue 6, pp. 871 - 881
Abstract The Cys22-Cys27 disulfide bond of factor X (FX) protease domain is not conserved among coagulation factors and its contribution to the physiological... 
Coagulation and Fibrinolysis | disulfide bond | Cys27 | molecular dynamic simulations | oxidation/reduction balance | coagulation factor X | SYSTEM | MECHANISM | reduction balance | DEFECT | oxidation | FACTOR IXA | TERNARY COMPLEX | MUTATION | DYNAMICS | PERIPHERAL VASCULAR DISEASE | SWITCH | HEMATOLOGY | MOLECULAR-BASIS | ZYMOGEN
Journal Article