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Haemophilia : the official journal of the World Federation of Hemophilia, ISSN 1351-8216, 01/2016, Volume 22, Issue 1, pp. 54 - 64
Journal Article
Haemophilia : the official journal of the World Federation of Hemophilia, ISSN 1351-8216, 01/2016, Volume 22, Issue 1, pp. 87 - 95
Journal Article
Journal of thrombosis and haemostasis, ISSN 1538-7933, 11/2014, Volume 12, Issue 11, pp. 1788 - 1800
Summary Background Routine prophylaxis with replacement factor VIII (FVIII) – the standard of care for severe hemophilia A – often requires frequent... 
pharmacokinetics | factor VIII | hemophilia A | administration schedule | recombinant fusion proteins | drug | Drug | Administration schedule | Pharmacokinetics | Recombinant fusion proteins | Hemophilia A | Factor VIII | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Recombinant Fusion Proteins - adverse effects | Factor VIII - pharmacokinetics | Humans | Half-Life | Male | Hemorrhage - prevention & control | Immunoglobulin Fc Fragments - administration & dosage | Young Adult | Time Factors | Computer Simulation | Coagulants - administration & dosage | Adult | Factor VIII - adverse effects | Coagulants - pharmacokinetics | Hemophilia A - diagnosis | Immunoglobulin Fc Fragments - adverse effects | Immunoglobulin Fc Fragments - blood | Recombinant Fusion Proteins - administration & dosage | von Willebrand Factor - metabolism | Hemostasis - drug effects | Severity of Illness Index | Drug Administration Schedule | Treatment Outcome | Biomarkers - blood | Coagulants - blood | Hemophilia A - blood | Recombinant Fusion Proteins - blood | Models, Biological | Recombinant Fusion Proteins - pharmacokinetics | Adolescent | Factor VIII - administration & dosage | Hemorrhage - chemically induced | Infusions, Intravenous | Coagulants - adverse effects | Drug Monitoring | Hemophilia A - drug therapy | Proteins | Blood coagulation factor VIII | Analysis | Von Willebrand factor | Hemophilia | Index Medicus
Journal Article
Journal Article
British journal of haematology, ISSN 0007-1048, 02/2012, Volume 156, Issue 3, pp. 295 - 302
Summary Monogenic hereditary diseases, such as haemophilia A and B, are ideal targets for gene therapeutic approaches. While these diseases can be treated with... 
haemophilia | factor VIII (FVIII) | factor IX (FIX) | gene therapy | immune tolerance | Haemophilia | Factor IX (FIX) | Factor VIII (FVIII) | Gene therapy | Immune tolerance | Life Sciences & Biomedicine | Hematology | Science & Technology | Hemophilia B - therapy | Recombinant Fusion Proteins - immunology | Dependovirus - genetics | Factor IX - antagonists & inhibitors | Factor VIII - immunology | Isoantibodies - biosynthesis | Factor IX - therapeutic use | Humans | Recombinant Fusion Proteins - therapeutic use | Genetic Vectors - adverse effects | Male | Genetic Vectors - therapeutic use | T-Lymphocytes, Regulatory - immunology | Recombinant Fusion Proteins - antagonists & inhibitors | Retroviridae - genetics | Factor VIII - antagonists & inhibitors | Female | Factor VIII - therapeutic use | Recombinant Fusion Proteins - biosynthesis | Gene Transfer Techniques | Factor IX - immunology | Genetic Vectors - immunology | Gene Expression Regulation | Genes, Synthetic | Factor VIII - genetics | Immune Tolerance | Cell Transplantation | Dependovirus - immunology | Factor IX - genetics | Hemophilia B - genetics | Hemophilia A - therapy | Forecasting | Genetic Vectors - genetics | Recombinant Fusion Proteins - genetics | Hemophilia A - genetics | Factor VIII - biosynthesis | Clinical Trials, Phase I as Topic | Factor IX - biosynthesis | Genetic Therapy - methods | Prevention | Anopheles | Care and treatment | Blood coagulation factor VIII | Genes | Hemophilia | Health aspects | Prothrombin complex concentrate | Index Medicus | inhibitors | vectors | factor VIII (F8) | factor IX (F9)
Journal Article