Articles

UofT Libraries is getting a new library services platform in January 2021.
Learn more about the change.

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
science & technology (391) 391
life sciences & biomedicine (382) 382
humans (369) 369
neurosciences & neurology (237) 237
female (206) 206
male (206) 206
neurosciences (189) 189
amyotrophic lateral sclerosis (179) 179
amyotrophic lateral sclerosis - genetics (175) 175
middle aged (152) 152
familial amyotrophic lateral sclerosis (150) 150
neurology (150) 150
clinical neurology (149) 149
mutation (139) 139
adult (125) 125
superoxide dismutase - genetics (125) 125
biological and medical sciences (114) 114
medicine & public health (114) 114
medical sciences (110) 110
genetic aspects (106) 106
aged (91) 91
animals (87) 87
superoxide dismutase-1 (85) 85
familial als (84) 84
pedigree (83) 83
familial (65) 65
degenerative and inherited degenerative diseases of the nervous system. leukodystrophies. prion diseases (64) 64
amyotrophic lateral sclerosis - pathology (59) 59
biochemistry & molecular biology (59) 59
analysis (58) 58
internal medicine (57) 57
mice (54) 54
mutation - genetics (51) 51
pathology (51) 51
motor neuron disease (46) 46
superoxide dismutase - metabolism (46) 46
als (44) 44
genetics (43) 43
nervous system (41) 41
amyotrophic lateral sclerosis - metabolism (39) 39
phenotype (39) 39
sod1 (38) 38
superoxide dismutase (37) 37
amyotrophic lateral sclerosis - enzymology (36) 36
dna mutational analysis (35) 35
nervous system diseases (35) 35
research (34) 34
risk factors (34) 34
amyotrophic lateral sclerosis - physiopathology (33) 33
genes (33) 33
adolescent (32) 32
geriatrics & gerontology (32) 32
dementia (31) 31
mice, transgenic (31) 31
aged, 80 and over (30) 30
superoxide (30) 30
cell biology (29) 29
age of onset (28) 28
disease models, animal (28) 28
family health (28) 28
genetic predisposition to disease (28) 28
genetic research (28) 28
disease progression (27) 27
neurodegeneration (27) 27
point mutation (27) 27
spinal cord - pathology (27) 27
development and progression (26) 26
neurons (26) 26
oncology (26) 26
familial hypercholesterolemia (25) 25
surgery (25) 25
brain - pathology (24) 24
familial adenomatous polyposis (24) 24
familial mediterranean fever (24) 24
gene mutations (24) 24
genetic testing (23) 23
alzheimer's disease (22) 22
amyotrophic lateral sclerosis - diagnosis (22) 22
dna-binding proteins - genetics (22) 22
genetics & heredity (22) 22
young adult (22) 22
child (21) 21
cohort studies (21) 21
frontotemporal dementia (21) 21
medicine (21) 21
cardiology (20) 20
aging (19) 19
epidemiology (19) 19
family (19) 19
genotype (19) 19
immunohistochemistry (19) 19
motor neurons - pathology (19) 19
diagnosis, differential (18) 18
genetic predisposition to disease - genetics (18) 18
pediatrics (18) 18
rna-binding protein fus - genetics (18) 18
age (17) 17
exons - genetics (17) 17
gastroenterology (17) 17
medical research (17) 17
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (4) 4
Criminology - Stacks (2) 2
Baycrest Hospital - Stacks (1) 1
Collection Dvlpm't (Acquisitions) - Vendor file (1) 1
New College (Ivey) - Stacks (1) 1
Robarts - Stacks (1) 1
UofT at Mississauga - Stacks (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (546) 546
German (165) 165
Japanese (16) 16
French (7) 7
Dutch (3) 3
Catalan (1) 1
Chinese (1) 1
Norwegian (1) 1
Portuguese (1) 1
Spanish (1) 1
Turkish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Sequestosome 1/p62 links familial ALS mutant SOD1 to LC3 via an ubiquitin‐independent mechanism
by Gal, Jozsef and Ström, Anna‐Lena and Kwinter, David M and Kilty, Renée and Zhang, Jiayu and Shi, Ping and Fu, Weisi and Wooten, Marie W and Zhu, Haining
Journal of neurochemistry, ISSN 0022-3042, 11/2009, Volume 111, Issue 4, pp. 1062 - 1073
sequestosome 1/p62 | mutant superoxide dismutase 1 | autophagy | familial amyotrophic lateral sclerosis | Familial amyotrophic lateral sclerosis | Sequestosome 1/p62 | Autophagy | Mutant superoxide dismutase 1 | Biochemistry & Molecular Biology | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Neurology | Biological and medical sciences | Medical sciences | Cerebrospinal fluid. Meninges. Spinal cord | Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases | Nervous system (semeiology, syndromes) | Superoxide Dismutase - genetics | Immunoprecipitation | Microtubule-Associated Proteins - genetics | Embryo, Mammalian | Microtubule-Associated Proteins - metabolism | Sequestosome-1 Protein | Humans | Ubiquitin - metabolism | Heat-Shock Proteins - genetics | Transfection | Spinal Cord - cytology | Superoxide Dismutase - metabolism | Heat-Shock Proteins - metabolism | Mice, Inbred C57BL | Cells, Cultured | Ubiquitin - genetics | Mutation - genetics | Motor Neurons - metabolism | Superoxide Dismutase - chemistry | Animals | Adaptor Proteins, Signal Transducing - genetics | Protein Binding | Mice | Adaptor Proteins, Signal Transducing - metabolism | Protein Structure, Tertiary - physiology | Proteins | Superoxide dismutase | Amyotrophic lateral sclerosis | Genetic aspects | Superoxide | Biochemistry | Neurological disorders | Index Medicus | mutant SOD1 | familial ALS | Sequestosome 1 | p62
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Sporadic and hereditary amyotrophic lateral sclerosis (ALS)
by Ajroud-Driss, Senda and Siddique, Teepu
Biochimica et biophysica acta. Molecular basis of disease, ISSN 0925-4439, 04/2015, Volume 1852, Issue 4, pp. 679 - 684
Familial ALS | Pathogenesis | Sporadic ALS | Paradigm shift | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | RNA-Binding Proteins - genetics | Superoxide Dismutase - genetics | Ubiquitins - genetics | Epigenesis, Genetic | Humans | Adaptor Proteins, Vesicular Transport - genetics | Genetic Diseases, Inborn - genetics | Genetic Diseases, Inborn - pathology | Adaptor Proteins, Vesicular Transport - metabolism | Motor Neurons - pathology | DNA-Binding Proteins - metabolism | Cell Cycle Proteins - genetics | C9orf72 Protein | Genetic Diseases, Inborn - metabolism | Ubiquitins - metabolism | Superoxide Dismutase - metabolism | Cell Survival | Amyotrophic Lateral Sclerosis - genetics | Cell Cycle Proteins - metabolism | RNA-Binding Protein FUS - genetics | RNA-Binding Protein FUS - metabolism | DNA-Binding Proteins - genetics | Motor Neurons - metabolism | Proteins - genetics | Amyotrophic Lateral Sclerosis - pathology | Animals | Proteins - metabolism | Amyotrophic Lateral Sclerosis - metabolism | Mice | Superoxide Dismutase-1 | RNA-Binding Proteins - metabolism | Epigenetic inheritance | Amyotrophic lateral sclerosis | Development and progression | Genetic aspects | Proteolysis | Analysis
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text FUS , TARDBP , and SOD1 mutations in a Taiwanese cohort with familial ALS
by Tsai, Ching-Paio and Soong, Bing-Wen and Lin, Kon-Ping and Tu, Pang-Hsien and Lin, Jer-Li and Lee, Yi-Chung
Neurobiology of aging, ISSN 0197-4580, 2011, Volume 32, Issue 3, pp. 553.e13 - 553.e21
Neurology | Internal Medicine | FIG4 | FUS | VAPB | TDP-43 | CHMP2B | Amyotrophic lateral sclerosis | Familial amyotrophic lateral sclerosis | ANG | SOD1 | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Geriatrics & Gerontology | Science & Technology | Superoxide Dismutase - genetics | Amyotrophic Lateral Sclerosis - genetics | Humans | Middle Aged | RNA-Binding Protein FUS - genetics | Male | Taiwan - ethnology | DNA Mutational Analysis - methods | DNA-Binding Proteins - genetics | Mutation - genetics | Animals | Pedigree | Taiwan - epidemiology | Adult | Female | Superoxide Dismutase-1 | Cohort Studies | Evolution, Molecular | Analysis | Genetic aspects | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text ALS-associated missense and nonsense TBK1 mutations can both cause loss of kinase function
by de Majo, Martina and Topp, Simon D and Smith, Bradley N and Nishimura, Agnes L and Chen, Han-Jou and Gkazi, Athina Soragia and Miller, Jack and Wong, Chun Hao and Vance, Caroline and Baas, Frank and ten Asbroek, Anneloor L.M.A and Kenna, Kevin P and Ticozzi, Nicola and Redondo, Alberto Garcia and Esteban-Pérez, Jesús and Tiloca, Cinzia and Verde, Federico and Duga, Stefano and Morrison, Karen E and Shaw, Pamela J and Kirby, Janine and Turner, Martin R and Talbot, Kevin and Hardiman, Orla and Glass, Jonathan D and de Belleroche, Jacqueline and Gellera, Cinzia and Ratti, Antonia and Al-Chalabi, Ammar and Brown, Robert H and Silani, Vincenzo and Landers, John E and Shaw, Christopher E
Neurobiology of aging, ISSN 0197-4580, 11/2018, Volume 71, pp. 266.e1 - 266.e10
ALS | Familial ALS | TBK1 | WES | FTD | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Geriatrics & Gerontology | Science & Technology | Protein Structure, Tertiary | Phosphorylation | Genetic Association Studies | Exons | Amyotrophic Lateral Sclerosis - genetics | Humans | Protein-Serine-Threonine Kinases - genetics | Transcription Factor TFIIIA - genetics | Male | Codon, Nonsense | Mutation, Missense | Interferon Regulatory Factor-3 - genetics | Protein Binding | Female | Protein-Serine-Threonine Kinases - chemistry | Medicine, Experimental | Medical research | Genetic aspects | Analysis | Genomics | Medical genetics | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS)
by Crippa, Valeria and Sau, Daniela and Rusmini, Paola and Boncoraglio, Alessana and Onesto, Elisa and Bolzoni, Elena and Galbiati, Mariarita and Fontana, Elena and Marino, Marianna and Carra, Serena and Bendotti, Caterina and De Biasi, Silvia and Poletti, Angelo
Human molecular genetics, ISSN 0964-6906, 09/2010, Volume 19, Issue 17, pp. 3440 - 3456
MOTOR-NEURONS | CHAPERONE ACTIVITY | ANDROGEN RECEPTOR | MUTANT MICE | MARIE-TOOTH-DISEASE | POLYGLUTAMINE TRACT | 5-ALPHA-REDUCTASE TYPE-2 | SPINAL-CORD | MUTATIONS | UMCG Approved | FAMILIAL ALS | Biochemistry & Molecular Biology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Superoxide Dismutase - genetics | Amyotrophic Lateral Sclerosis - physiopathology | Humans | HSP20 Heat-Shock Proteins - genetics | Male | Autophagy | HSP20 Heat-Shock Proteins - metabolism | DNA-Binding Proteins - metabolism | Heat-Shock Proteins - genetics | Muscle Proteins - metabolism | Female | Protein-Serine-Threonine Kinases - metabolism | Superoxide Dismutase - metabolism | Cell Line | Amyotrophic Lateral Sclerosis - genetics | Heat-Shock Proteins - metabolism | Mice, Inbred C57BL | Protein-Serine-Threonine Kinases - genetics | Mice, Transgenic | DNA-Binding Proteins - genetics | Protein Folding | Motor Neurons - metabolism | Muscle Proteins - genetics | Superoxide Dismutase - chemistry | Animals | Amyotrophic Lateral Sclerosis - metabolism | Mice | Superoxide Dismutase-1 | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Knockdown of GADD34 in neonatal mutant SOD1 mice ameliorates ALS
by Ghadge, Ghanashyam D and Sonobe, Yoshifumi and Camarena, Adrian and Drigotas, Claire and Rigo, Frank and Ling, Karen K and Roos, Raymond P
Neurobiology of disease, ISSN 0969-9961, 03/2020, Volume 136, pp. 104702 - 104702
GADD34 | Integrated stress response | shRNA | Familial amyotrophic lateral sclerosis | CHOP | Antisense oligonucleotides | Mutant Cu/Zn superoxide dismutase | Unfolded protein response | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Sequestosome-1 (SQSTM1) sequence variants in ALS cases in the UK: Prevalence and coexistence of SQSTM1 mutations in ALS kindred with PDB
by Kwok, Chun T and Morris, Alex and De Belleroche, Jacqueline S
European journal of human genetics : EJHG, ISSN 1018-4813, 2014, Volume 22, Issue 4, pp. 492 - 496
Familial ALS | Amyotrophic lateral sclerosis | p62 | Sequestosome-1(SQSTM1) | Paget's disease of bone | Biochemistry & Molecular Biology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Haplotypes | Exons | Sequestosome-1 Protein | Amyotrophic Lateral Sclerosis - genetics | Humans | Middle Aged | Databases, Genetic | Male | United Kingdom | Sequence Analysis, DNA | Osteitis Deformans - genetics | Genetic Variation | Pedigree | Adaptor Proteins, Signal Transducing - genetics | Female | Heterozygote | Aged | Mutation | Cohort Studies | Paget's disease | Pathogenicity | Proteins | Homeostasis | Coexistence | Deoxyribonucleic acid--DNA | Apoptosis | Index Medicus | paget's disease of bone | sequestosome-1(SQSTM1) | familial ALS | amyotrophic lateral sclerosis
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Lost in translation: Treatment trials in the SOD1 mouse and in human ALS
by Benatar, Michael
Neurobiology of disease, ISSN 0969-9961, 2007, Volume 26, Issue 1, pp. 1 - 13
Neurology | SOD1 mouse | Familial ALS | G93A | Animal model | Treatment trials | Motor neuron disease | Systematic review | Amyotrophic lateral sclerosis | Mouse model | Meta-analysis | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Superoxide Dismutase - genetics | Animals | Amyotrophic Lateral Sclerosis - genetics | Humans | Survival Analysis | Publication Bias | Mice | Sex Characteristics | Superoxide Dismutase-1 | Research Design | Amyotrophic Lateral Sclerosis - drug therapy | Disease Models, Animal | Clinical trials | Analysis | Porphyrins | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Screening of the SOD1, FUS, TARDBP, ANG , and OPTN mutations in Korean patients with familial and sporadic ALS
by Kwon, Min-Jung and Baek, Wonki and Ki, Chang-Seok and Kim, Hyun Young and Koh, Seong-Ho and Kim, Jong-Won and Kim, Seung Hyun
Neurobiology of aging, ISSN 0197-4580, 2012, Volume 33, Issue 5, pp. 1017.e17 - 1017.e23
Neurology | Internal Medicine | Sporadic | FUS | Familial | Amyotrophic lateral sclerosis | Korean | Mutation | SOD1 | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Geriatrics & Gerontology | Science & Technology | Genetic Predisposition to Disease - genetics | Superoxide Dismutase - genetics | Amyotrophic Lateral Sclerosis - genetics | Humans | Middle Aged | Ribonuclease, Pancreatic - genetics | Asian Continental Ancestry Group - genetics | Transcription Factor TFIIIA - genetics | RNA-Binding Protein FUS - genetics | Male | Amyotrophic Lateral Sclerosis - ethnology | DNA-Binding Proteins - genetics | Genetic Testing - methods | Pedigree | Aged, 80 and over | Adult | Female | Genetic Predisposition to Disease - ethnology | Aged | Superoxide Dismutase-1 | Republic of Korea - epidemiology | FUS protein | Gene frequency | Ethnic groups | Aging | FUS gene | Nervous system | Superoxide dismutase | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights