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Journal of the American College of Cardiology, ISSN 0735-1097, 2018, Volume 72, Issue 6, pp. 662 - 680
Journal Article
Atherosclerosis, ISSN 0021-9150, 08/2017, Volume 263, pp. 405 - 411
Familial hypercholesterolemia (FH) is a common inherited disorder of low density lipoprotein-cholesterol (LDL-C) metabolism... 
Carotid intima media thickness | Coronary artery calcification | Polygenic hypercholesterolemia | Familial hypercholesterolemia | Preclinical atherosclerosis | INTIMA-MEDIA THICKNESS | DIAGNOSIS | MUTATION DETECTION | CARDIAC & CARDIOVASCULAR SYSTEMS | RISK | GENETIC CAUSES | BEAM COMPUTED-TOMOGRAPHY | LIPOPROTEIN | UK | PERIPHERAL VASCULAR DISEASE | CORONARY-HEART-DISEASE | PROGRESSION | Humans | Middle Aged | England | Male | Asymptomatic Diseases | Coronary Artery Disease - blood | Multifactorial Inheritance | Netherlands | Carotid Artery Diseases - diagnostic imaging | Coronary Angiography - methods | DNA Mutational Analysis | Adult | Cholesterol, LDL - blood | Female | Hyperlipoproteinemia Type II - drug therapy | Hyperlipoproteinemia Type II - complications | Severity of Illness Index | Genetic Predisposition to Disease | Carotid Artery Diseases - etiology | Coronary Artery Disease - etiology | Hyperlipoproteinemia Type II - blood | Carotid Intima-Media Thickness | Risk Factors | Biomarkers - blood | Computed Tomography Angiography | Coronary Artery Disease - diagnostic imaging | Phenotype | Carotid Artery Diseases - blood | Aged | Polymorphism, Single Nucleotide | Mutation | Hyperlipoproteinemia Type II - genetics | Heart | Genetic aspects | Hypercholesterolemia | Coronary heart disease | Low density lipoproteins | Atherosclerosis | Cardiac patients | Physiological aspects | Single nucleotide polymorphisms
Journal Article
Endocrinology and Metabolism Clinics of North America, ISSN 0889-8529, 03/2016, Volume 45, Issue 1, pp. 1 - 16
Familial hypercholesterolemia is a common, inherited disorder of cholesterol metabolism that leads to early cardiovascular morbidity and mortality... 
LDL apheresis | Lomitapide | Ezetimibe | Mipomersen | Familial hypercholesterolemia | Bile acid sequestrants | Statins | TRIGLYCERIDE TRANSFER PROTEIN | CHOLESTEROL | SAFETY | LOW-DENSITY-LIPOPROTEIN | MONOCLONAL-ANTIBODY | LDL | ENDOCRINOLOGY & METABOLISM | ASSOCIATION EXPERT PANEL | DOUBLE-BLIND | STATIN | AMG 145
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 03/2015, Volume 35, Issue 3, pp. 689 - 699
Journal Article
Circulation, ISSN 0009-7322, 01/2014, Volume 129, Issue 2, pp. 234 - 243
Journal Article
Circulation: Cardiovascular Genetics, ISSN 1942-325X, 06/2016, Volume 9, Issue 3, pp. 240 - 249
BACKGROUND—Cardiovascular disease burden and treatment patterns among patients with familial hypercholesterolemia (FH... 
coronary artery disease | CARDIAC & CARDIOVASCULAR SYSTEMS | RISK-FACTORS | BLOOD CHOLESTEROL | genetic heart disease | low-density lipoprotein cholesterol | GUIDANCE | PREVALENCE | AMERICAN-HEART-ASSOCIATION | statin therapy | familial hypercholesterolemia | CHOLESTEROL LEVELS | GENETICS & HEREDITY | ASSOCIATION EXPERT PANEL | CARDIOVASCULAR-DISEASE | LOWERING TREATMENT | CORONARY-ARTERY-DISEASE | Multivariate Analysis | Predictive Value of Tests | Practice Patterns, Physicians' - standards | Prevalence | United States | Humans | Middle Aged | Coronary Disease - epidemiology | Male | Time Factors | Adult | Cholesterol, LDL - blood | Female | Registries | Hyperlipoproteinemia Type II - drug therapy | Hypertension - epidemiology | Odds Ratio | Professional Practice Gaps - standards | Genetic Predisposition to Disease | Cross-Sectional Studies | Hyperlipoproteinemia Type II - blood | Comorbidity | Down-Regulation | Risk Factors | Logistic Models | Treatment Outcome | Biomarkers - blood | Chi-Square Distribution | Coronary Disease - prevention & control | Phenotype | Guideline Adherence | Coronary Disease - genetics | Hyperlipoproteinemia Type II - epidemiology | Diabetes Mellitus - epidemiology | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Heterozygote | Aged | Early Diagnosis | Hyperlipoproteinemia Type II - genetics | Practice Guidelines as Topic
Journal Article
Atherosclerosis, ISSN 0021-9150, 2012, Volume 223, Issue 2, pp. 262 - 268
Abstract Homozygous familial hypercholesterolemia (HoFH) is an autosomal co-dominant disease resulting from mutations in both copies of the low-density lipoprotein receptor (LDLR) gene... 
Cardiovascular | Apolipoprotein B | Familial hypercholesterolemia | Homozygous | LDL receptor | LIVER-TRANSPLANTATION | CHOLESTEROL | ATORVASTATIN | INHIBITION | CORONARY ATHEROSCLEROSIS | RECOMMENDATIONS | GENETICS | ASSOCIATION EXPERT PANEL | LDL APHERESIS | CARDIOVASCULAR-DISEASE | PERIPHERAL VASCULAR DISEASE | Cardiovascular Diseases - prevention & control | Humans | Hyperlipoproteinemia Type II - diagnosis | Male | Blood Component Removal | Cardiovascular Diseases - genetics | Young Adult | Adult | Cholesterol, LDL - blood | Female | Hyperlipoproteinemia Type II - complications | Severity of Illness Index | Hyperlipoproteinemia Type II - therapy | Receptors, LDL - genetics | Genetic Predisposition to Disease | Hyperlipoproteinemia Type II - blood | Receptors, LDL - metabolism | Treatment Outcome | Biomarkers - blood | Disease Progression | Homozygote | Phenotype | Anticholesteremic Agents - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Adolescent | Mutation | Hyperlipoproteinemia Type II - genetics | Care and treatment | Hypercholesterolemia | Cardiac patients | Low density lipoproteins | Genes | Atherosclerosis | Carbohydrate metabolism | Diagnosis | Blood lipids | Statins | Cholesterol | Lipoprotein A | Development and progression | Apolipoproteins
Journal Article