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Scientific Reports, ISSN 2045-2322, 2017, Volume 7, Issue 1, pp. 3086 - 11
Journal Article
Cell, ISSN 0092-8674, 2007, Volume 129, Issue 7, pp. 1337 - 1349
Journal Article
Oncogene, ISSN 0950-9232, 03/2003, Volume 22, Issue 9, pp. 1281 - 1293
CC139 fibroblasts are one of several model systems in which the Raf --> MEK --> ERK1/2 pathway can inhibit apoptosis independently of the PI3K pathway;... 
PI3K | JNK | Raf | Bim | Apoptosis | ERK | NEURONAL APOPTOSIS | FORKHEAD TRANSCRIPTION FACTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | bim | BCL-2 FAMILY MEMBER | CYCLE ARREST | apoptosis | RELATIVE BIM | BH3 DOMAIN | CELL BIOLOGY | PROGRAMMED CELL-DEATH | ONCOLOGY | GENETICS & HEREDITY | MOLECULAR-CLONING | CYTOCHROME-C RELEASE | KINASE ACTIVATION
Journal Article
IMMUNITY, ISSN 1074-7613, 09/2003, Volume 19, Issue 3, pp. 341 - 352
After antigen-driven expansion, the majority of T cells involved in an immune response die rapidly by apoptosis dependent on the Bcl-2 related proteins, Bim... 
PROGRAMMED CELL-DEATH | APOPTOSIS | FAMILY MEMBER BIM | BCL-2 PROTEIN FAMILY | IN-VIVO | OUTER MITOCHONDRIAL-MEMBRANE | IMMUNOLOGY | CYTOCHROME-C RELEASE | BAX OLIGOMERIZATION | T-CELLS | BH3 DOMAIN
Journal Article
Blood, ISSN 0006-4971, 12/2005, Volume 106, Issue 13, pp. 4131 - 4138
Journal Article
Nature Immunology, ISSN 1529-2908, 08/2007, Volume 8, Issue 8, pp. 856 - 863
Interleukin 15 (IL-15) promotes the survival of natural killer (NK) cells by preventing apoptosis through mechanisms unknown at present. Here we identify Bim,... 
FORKHEAD TRANSCRIPTION FACTOR | HOMEOSTASIS | B-CELL | LYMPHOID DEVELOPMENT | APOPTOTIC RESPONSES | FACTOR FKHR-L1 | DEFICIENT MICE | IMMUNOLOGY | FAMILY-MEMBER BIM | BCL-2 FAMILY | BH3-ONLY PROTEINS | Forkhead Transcription Factors - immunology | Proto-Oncogene Proteins c-bcl-2 - immunology | Neoplasm Proteins - immunology | Immunoblotting | Phosphatidylinositol 3-Kinases - metabolism | Neoplasm Proteins - metabolism | Interleukin-15 - immunology | Phosphatidylinositol 3-Kinases - immunology | Proto-Oncogene Proteins c-bcl-2 - metabolism | Flow Cytometry | Bcl-2-Like Protein 11 | Forkhead Transcription Factors - metabolism | Polymerase Chain Reaction | Proto-Oncogene Proteins - immunology | Killer Cells, Natural - immunology | Membrane Proteins - metabolism | Proto-Oncogene Proteins - metabolism | Mitogen-Activated Protein Kinase 3 - immunology | Apoptosis Regulatory Proteins - immunology | Membrane Proteins - immunology | Cell Survival - immunology | Apoptosis Regulatory Proteins - metabolism | Animals | Apoptosis - immunology | Mitogen-Activated Protein Kinase 3 - metabolism | Interleukin-15 - metabolism | Myeloid Cell Leukemia Sequence 1 Protein | Mice | Killer Cells, Natural - metabolism | Forkhead Box Protein O3 | Antigen receptors, T cell | Receptors | Physiological aspects | Interleukin-15 | Research | T cells | Apoptosis | Index Medicus
Journal Article
Journal Article
Journal Article
Journal Article
Journal Article
Immunity, ISSN 1074-7613, 02/2008, Volume 28, Issue 2, pp. 197 - 205
Apoptotic death of T lymphocytes is critical for shutdown of immune responses and hemopoietic cell homeostasis. Both death receptor (Fas) activation and... 
MOLIMMUNO | BCL-2 | T-CELL RESPONSES | ENTEROTOXIN-B | IN-VIVO | DEATH | LIGAND | IMMUNOLOGY | FAMILY-MEMBER BIM | BH3-ONLY PROTEINS | VIRAL-INFECTION | DELETION | Autoimmunity | T-Lymphocyte Subsets - immunology | Ovalbumin - immunology | T-Lymphocyte Subsets - physiology | fas Receptor - metabolism | Gammaherpesvirinae - immunology | Membrane Proteins - deficiency | fas Receptor - immunology | Bcl-2-Like Protein 11 | Apoptosis Regulatory Proteins - deficiency | Mice, Mutant Strains | Proto-Oncogene Proteins - immunology | fas Receptor - genetics | CD8-Positive T-Lymphocytes - metabolism | Herpesvirus 1, Human - immunology | Membrane Proteins - metabolism | Proto-Oncogene Proteins - metabolism | Apoptosis Regulatory Proteins - immunology | Lymphatic Diseases - immunology | Mice, Inbred C57BL | Membrane Proteins - immunology | Proto-Oncogene Proteins - deficiency | CD8-Positive T-Lymphocytes - physiology | Apoptosis Regulatory Proteins - metabolism | Herpes Simplex - immunology | Herpes Simplex - virology | Lymphatic Diseases - metabolism | Animals | T-Lymphocyte Subsets - metabolism | Mice | CD8-Positive T-Lymphocytes - immunology | Chronic Disease | Apoptosis | Herpesviridae Infections - immunology | Prevention | Immune response | Molecular genetics | Oncology, Experimental | Research | T cells | Health aspects | Cancer | Proteins | Lymphocytes | Transgenic animals | Leukemia | DNA damage | Homeostasis | T cell receptors | Viral infections | Immune system | Index Medicus
Journal Article
Molecular Cell, ISSN 1097-2765, 11/2009, Volume 36, Issue 3, pp. 487 - 499
While activation of BAX/BAK by BH3-only molecules (BH3s) is essential for mitochondrial apoptosis, the underlying mechanisms remain unsettled. Here we... 
CELLCYCLE | CYTOCHROME-C | PROAPOPTOTIC BAX | OLIGOMERIZES BAK | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENDOPLASMIC-RETICULUM | SUBCELLULAR LOCATION | PROTEINS | BCL-2 FAMILY-MEMBERS | BH3 DOMAIN | CELL-DEATH | MEMBRANE PERMEABILIZATION | CELL BIOLOGY | bcl-2-Associated X Protein - chemistry | Immunoprecipitation | Apoptosis - drug effects | Protein Multimerization | bcl-2 Homologous Antagonist-Killer Protein - genetics | Immunoblotting | BH3 Interacting Domain Death Agonist Protein - genetics | Green Fluorescent Proteins - genetics | bcl-2 Homologous Antagonist-Killer Protein - metabolism | Bcl-2-Like Protein 11 | Protein Binding - drug effects | Tumor Suppressor Proteins - genetics | Apoptosis Regulatory Proteins - genetics | Membrane Proteins - metabolism | BH3 Interacting Domain Death Agonist Protein - metabolism | bcl-2-Associated X Protein - genetics | Fibroblasts - metabolism | Proto-Oncogene Proteins - metabolism | Green Fluorescent Proteins - metabolism | Tumor Suppressor Proteins - metabolism | Membrane Proteins - genetics | Cells, Cultured | bcl-2-Associated X Protein - metabolism | Etoposide - pharmacology | Proto-Oncogene Proteins - genetics | Mitochondria - metabolism | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Animals | Models, Biological | Tunicamycin - pharmacology | Fibroblasts - drug effects | Thapsigargin - pharmacology | Fibroblasts - cytology | Mice | Mutation | Microscopy, Fluorescence | Staurosporine - pharmacology | bcl-2 Homologous Antagonist-Killer Protein - chemistry | Monomers | Apoptosis | Oligomers | Index Medicus
Journal Article