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12/2011
Background : Natural honey is widely used all over the world as a complementary and alternative medicine in various disorders including Fanconi anemia (FA). FA... 
mitomycin-C | hony | Fanconi anemia | Chromosomal breakage
Web Resource
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, ISSN 1083-8791, 07/2019
It is well known that pharmacokinetics (PK) guided busulfan (BU) dosing increases engraftment rates and lowers hepatotoxicity in patients undergoing... 
Index Medicus
Journal Article
BLOOD, ISSN 0006-4971, 07/2014, Volume 124, Issue 5, pp. 822 - 826
Twenty-three children with nonmalignant disorders received HLA-haploidentical hematopoietic stem cell transplantation (haplo-HSCT) after ex vivo elimination of... 
THALASSEMIA | GRAFT | DONORS | HEMATOLOGY | VERSUS-HOST-DISEASE | APLASTIC-ANEMIA | FANCONI-ANEMIA | MARROW TRANSPLANTATION | INNATE IMMUNITY | BLOOD | LYMPHOCYTES
Journal Article
02/2012
Background: Fanconi anemia (FA) is a rare autosomal recessive genetic disorder that shows an increased sensitivity to the intercalating agents such as... 
mitomycin C | chromosomal breakage | Fanconi anemia | Aplastic anemia
Web Resource
Genes and Development, ISSN 0890-9369, 08/2004, Volume 18, Issue 16, pp. 1958 - 1963
Journal Article
Journal Article
Nature Reviews Molecular Cell Biology, ISSN 1471-0072, 06/2016, Volume 17, Issue 6, pp. 330 - 331
Journal Article
Methods in Enzymology, ISSN 0076-6879, 01/2019, Volume 618, pp. 73 - 104
In higher eukaryotes, DNA damage repair response pathways are orchestrated by several molecular signals including ubiquitination. In particular the repair of... 
USP1 | RING E3 | Ubiquitination | Fanconi anemia | DNA repair | Ubiquitin E2
Journal Article
Biological and Pharmaceutical Bulletin, ISSN 0918-6158, 2017
Cisplatin is an anticancer agent and induces DNA interstrand cross-links (ICLs). ICLs activate various signaling processes and induce DNA repair pathways,... 
Monoubiquitination | Fanconi anemia pathway | Cisplatin | Caffeine
Journal Article
DNA repair, ISSN 1568-7864, 07/2019, p. 102657
Faithful duplication of the genome is critical for the survival of an organism and prevention of malignant transformation. Accurate replication of a large... 
Journal Article
MOLECULAR CELL, ISSN 1097-2765, 03/2013, Volume 49, Issue 5, pp. 795 - 807
Ubiquitylation and sumoylation, the covalent attachment of the polypeptides ubiquitin and SUMO, respectively, to target proteins, are pervasive mechanisms for... 
RNA-POLYMERASE-II | E3 LIGASE | HISTONE UBIQUITINATION | INDUCED UBIQUITYLATION | SELECTIVE SEGREGASE | FANCONI-ANEMIA PATHWAY | CROSS-LINK REPAIR | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOUBLE-STRAND BREAKS | BRCA1 TUMOR SUPPRESSION | HOMOLOGOUS RECOMBINATION | CELL BIOLOGY
Journal Article
2007, Monographs in human genetics, ISBN 9783805582773, Volume 15
Web Resource
BLOOD, ISSN 0006-4971, 12/2011, Volume 118, Issue 24, pp. 6392 - 6398
Proinflammatory cytokines such as TNF alpha are elevated in patients with myeloproliferative neoplasms (MPN), but their contribution to disease pathogenesis is... 
TUMOR-NECROSIS-FACTOR | STEM-CELLS | IN-VITRO | HEMATOPOIETIC PROGENITOR CELLS | BONE-MARROW | DISEASE | MUTATIONS | JAK2 | INHIBITOR | HEMATOLOGY | FANCONI-ANEMIA
Journal Article
ISSN 0027-8424, 2017
RAD51 is an indispensable homologous recombination protein, necessary for strand invasion and crossing over. It has recently been designated as a Fanconi... 
stem cells | hematopoiesis | fanconi anemia | inflammation | cytokine effects
Journal Article
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