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11/2012
Fatty acid synthase (FAS) is over-expressed in many human cancers and its activity is required for cancer cell survival. To understand why FAS is... 
cancer metabolism | 0992 | fatty acid synthase | 0570 | breast cancer | aerobic glycolysis
Dissertation
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2016, Volume 113, Issue 39, pp. 10848 - 10853
Journal Article
Nature Communications, ISSN 2041-1723, 06/2016, Volume 7, Issue 1, p. 11960
Besides the conventional carbon sources, acetyl-CoA has recently been shown to be generated from acetate in various types of cancers, where it promotes lipid... 
HISTONE H3 | C-11-ACETATE | MULTIDISCIPLINARY SCIENCES | ATP-CITRATE LYASE | ACETYL-COENZYME | GROWTH | GENE-EXPRESSION | SYNTHETASE | FATTY-ACID SYNTHASE | OVARIAN-CANCER CELL | PET
Journal Article
ONCOGENESIS, ISSN 2157-9024, 01/2016, Volume 5, Issue 1, pp. e189 - e189
Many human diseases, including metabolic, immune and central nervous system disorders, as well as cancer, are the consequence of an alteration in lipid... 
BREAST-CANCER | UNFOLDED PROTEIN RESPONSE | ONCOLOGY | DE-NOVO LIPOGENESIS | DOWNSTREAM SIGNALING MOLECULES | ATP-CITRATE LYASE | POTENTIAL THERAPEUTIC TARGET | TUMOR-CELLS | FATTY-ACID SYNTHASE | ENDOPLASMIC-RETICULUM STRESS | CHOLESTERYL ESTER ACCUMULATION | Enzymes | Lipids | Cellular biology | Metabolism | Cancer | Review
Journal Article
International Journal of Systematic and Evolutionary Microbiology, ISSN 1466-5026, 02/2016, Volume 66, Issue 2, pp. 928 - 938
Bacterial strains SBSr002(T) and SBSr003(T) were isolated in 2007 from dried soil samples containing decaying plant material. The organisms were recognized as... 
MICROBIOLOGY | FATTY-ACID SYNTHASE | SOIL MYXOBACTERIUM | BIOSYNTHESIS | NUCLEASE P1
Journal Article
Respirology, ISSN 1323-7799, 11/2018, Volume 23, Issue S2, pp. 134 - 134
Journal Article
JOURNAL OF MOLECULAR BIOLOGY, ISSN 0022-2836, 08/2016, Volume 428, Issue 16, pp. 3282 - 3294
The hexosamine biosynthetic pathway (HBP) is highly dependent on multiple metabolic nutrients including glucose, glutamine, and acetyl-CoA. Increased flux... 
signaling | GLCNACYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | GLCNAC TRANSFERASE | glycosylation | CELL-GROWTH | TET PROTEINS | N-ACETYLGLUCOSAMINE TRANSFERASE | HEXOSAMINE BIOSYNTHESIS | O-GIcNAcylation | PATHWAY | cancer | FATTY-ACID SYNTHASE | OGT
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 09/2008, Volume 49, Issue 9, pp. 1867 - 1874
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 10/2016, Volume 34, Issue 30, pp. 3655 - 3663
Purpose Obesity is an established risk factor for clear cell renal cell carcinoma (RCC); however, some reports suggest that RCC developing in obese patients... 
SURVIVAL | ONCOLOGY | PROGNOSIS | OBESITY PARADOX | OVERWEIGHT | RISK | MECHANISMS | FATTY-ACID SYNTHASE | CANCER | EXPRESSION | EPIDEMIOLOGY | Guc35 | Guc19 | Guc29 | Epid3 | ORIGINAL REPORTS | To16
Journal Article