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fbxw7 (240) 240
index medicus (202) 202
humans (187) 187
oncology (148) 148
f-box-wd repeat-containing protein 7 (123) 123
tumor-suppressor (109) 109
f-box proteins - genetics (100) 100
ubiquitin-protein ligases - genetics (99) 99
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mutation (79) 79
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expression (71) 71
ubiquitin-protein ligases - metabolism (71) 71
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cell line, tumor (63) 63
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fbw7 (62) 62
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genetic aspects (54) 54
cyclin-e (53) 53
gene expression regulation, neoplastic (53) 53
cell cycle (52) 52
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phosphorylation (49) 49
proteins (49) 49
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ubiquitin ligase (45) 45
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biochemistry & molecular biology (42) 42
health aspects (42) 42
fbxw7 mutations (40) 40
degradation (36) 36
gene (36) 36
proliferation (36) 36
aged (35) 35
micrornas - genetics (35) 35
ubiquitin (35) 35
notch1 (33) 33
research (33) 33
signal transduction (33) 33
article (32) 32
leukemia (32) 32
analysis (31) 31
f-box protein (31) 31
medical prognosis (31) 31
receptor, notch1 - genetics (31) 31
acute lymphoblastic-leukemia (30) 30
care and treatment (30) 30
colorectal cancer (30) 30
child (29) 29
precursor t-cell lymphoblastic leukemia-lymphoma - genetics (29) 29
adolescent (28) 28
fbw7 ubiquitin ligase (28) 28
growth (28) 28
ubiquitination (28) 28
differentiation (27) 27
invasion (27) 27
mutations (26) 26
development and progression (25) 25
microrna (25) 25
cdc4 protein (24) 24
p53 (24) 24
cell growth (23) 23
genes (23) 23
activation (22) 22
notch (22) 22
breast-cancer (21) 21
chemotherapy (21) 21
pathology (21) 21
t cells (21) 21
breast cancer (20) 20
genetics & heredity (20) 20
kinases (20) 20
mice, nude (20) 20
migration (20) 20
child, preschool (19) 19
f-box-wd repeat-containing protein 7 - genetics (19) 19
hcdc4 (19) 19
immunohistochemistry (19) 19
original (19) 19
stomach cancer (19) 19
survival (19) 19
tumorigenesis (19) 19
young adult (19) 19
biomarkers, tumor - genetics (18) 18
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protein (18) 18
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1. Full Text Frequent HRAS mutations in malignant ectomesenchymoma
by Huang, Shih-Chiang and Alaggio, Rita and Sung, Yun-Shao and Chen, Chun-Liang and Zhang, Lei and Kao, Yu-Chien and Agaram, Narasimhan P and Wexler, Leonard H and Antonescu, Cristina R
American Journal of Surgical Pathology, ISSN 0147-5185, 2016, Volume 40, Issue 7, pp. 876 - 885
ectomesenchymoma | PTPRD | rhabdomyosarcoma | FBXW7 | HRAS
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2. Full Text Tumor Suppression by the Fbw7 Ubiquitin Ligase: Mechanisms and Opportunities
by Davis, Ryan J and Welcker, Markus and Clurman, Bruce E
Cancer Cell, ISSN 1535-6108, 10/2014, Volume 26, Issue 4, pp. 455 - 464
Tumor suppressors with widespread impact on carcinogenesis control broad spectra of oncogenic pathways. Protein degradation is an emerging mechanism by which... 
PROMOTER HYPERMETHYLATION | FBXW7 BETA-FORM | CYCLIN-E | ONCOLOGY | ACUTE LYMPHOBLASTIC-LEUKEMIA | C-MYC | MULTISITE PHOSPHORYLATION | F-BOX PROTEIN | STEM-CELL DIFFERENTIATION | DEPENDENT DEGRADATION | SUBSTRATE RECOGNITION | CELL BIOLOGY | F-Box-WD Repeat-Containing Protein 7 | F-Box Proteins - physiology | Neoplasms - genetics | Humans | Cell Cycle Proteins - genetics | Mutation | Neoplasms - pathology | Ubiquitin-Protein Ligases - genetics | Ubiquitin-Protein Ligases - physiology | Cell Cycle Proteins - physiology | F-Box Proteins - genetics | Genes, Tumor Suppressor | Ubiquitin | Deregulation | Ligases | Proteolysis | Tumors | proteasome | hCDC4 | Fbxw7 | SCF | F-box protein | tumor suppressor | cancer | Fbw7 | ubiquitin | phosphodegron
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3. Full Text Fbxw7 regulates hepatocellular carcinoma migration and invasion via Notch 1 signaling pathway
by Wang, Xing and Zhang, Juan and Zhou, Liang and Sun, Wei and Zheng, Zhi-Gang and Lu, Peng and Gao, Yuan and Yang, Xi-Sheng and Zhang, Zhuo-Chao and Tao, Kai-Shan and Dou, Ke-Feng
International Journal of Oncology, ISSN 1019-6439, 07/2015, Volume 47, Issue 1, pp. 231 - 243
Notchl | Hepatocellular carcinoma | Fbxw7 | Migration | Invasion
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4. Full Text Prolyl‐isomerase Pin1 controls normal and cancer stem cells of the breast
by Rustighi, Alessandra and Zannini, Alessandro and Tiberi, Luca and Sommaggio, Roberta and Piazza, Silvano and Sorrentino, Giovanni and Nuzzo, Simona and Tuscano, Antonella and Eterno, Vincenzo and Benvenuti, Federica and Santarpia, Libero and Aifantis, Iannis and Rosato, Antonio and Bicciato, Silvio and Zambelli, Alberto and Del Sal, Giannino
EMBO Molecular Medicine, ISSN 1757-4676, 01/2014, Volume 6, Issue 1, pp. 99 - 119
Mammary epithelial stem cells are fundamental to maintain tissue integrity. Cancer stem cells (CSCs) are implicated in both treatment resistance and disease... 
stem cells | breast cancer | Fbxw7 E3 ubiquitin‐ligase | prolyl‐isomerase Pin1 | Notch | Breast cancer | Prolyl-isomerase Pin1 | Fbxw7 E3 ubiquitin-ligase | Stem cells | MEDICINE, RESEARCH & EXPERIMENTAL | APOPTOSIS | ACTIVATION | prolyl-isomerase Pin1 | PHOSPHORYLATION | MOLECULAR HETEROGENEITY | P53 | EPITHELIAL-MESENCHYMAL TRANSITION | THERAPEUTIC TARGET | TUMOR-SUPPRESSOR | GROWTH-FACTOR | F-Box-WD Repeat-Containing Protein 7 | Neoplastic Stem Cells - cytology | Receptors, Notch - metabolism | Humans | Peptidylprolyl Isomerase - antagonists & inhibitors | Receptors, Notch - genetics | Transplantation, Heterologous | Antineoplastic Agents - therapeutic use | Stem Cells - cytology | Stem Cells - metabolism | Breast Neoplasms - metabolism | Neoplastic Stem Cells - metabolism | Triple Negative Breast Neoplasms - pathology | Cell Cycle Proteins - genetics | Female | Peptidylprolyl Isomerase - metabolism | Peptidylprolyl Isomerase - genetics | Proto-Oncogene Proteins - metabolism | Mammary Glands, Human - cytology | Signal Transduction | F-Box Proteins - metabolism | Cell Cycle Proteins - metabolism | Ubiquitin-Protein Ligases - metabolism | Proto-Oncogene Proteins - genetics | NIMA-Interacting Peptidylprolyl Isomerase | Receptor, Notch1 - metabolism | Mice, SCID | Breast Neoplasms - drug therapy | Mice, Knockout | Animals | Breast Neoplasms - pathology | Triple Negative Breast Neoplasms - metabolism | Cell Line, Tumor | Mice | Receptor, Notch1 - genetics | Ubiquitin-Protein Ligases - genetics | F-Box Proteins - genetics | Receptor, Notch4 | Ubiquitin | Ligases | Phenotypes | Phosphorylation | Metastasis | Gene expression | Kinases | Pin1 protein | Experiments | Metastases | Signal transduction | Disease resistance | Cell fate | Proteasomes | Breast | Mutation | Ubiquitin-protein ligase | Tumors
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5. Full Text A novel transthyretin/STAT4/miR-223-3p/FBXW7 signaling pathway affects neovascularization in diabetic retinopathy
by Shao, Jun and Fan, Guangming and Yin, Xiaowen and Gu, Yu and Wang, Xiaolu and Xin, Yu and Yao, Yong
Molecular and Cellular Endocrinology, ISSN 0303-7207, 12/2019, Volume 498, p. 110541
MicroRNAs (miRNAs) are small RNAs without protein-coding functions that negatively regulate target genes and play important roles in physiological and... 
Diabetic retinopathy neovascularization | STAT4 | miR-223-3p | FBXW7 | Transthyretin
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6. Full Text Oncogenetic mutations combined with MRD improve outcome prediction in pediatric T-cell acute lymphoblastic leukemia
by Petit, Arnaud and Trinquand, Amélie and Chevret, Sylvie and Ballerini, Paola and Cayuela, Jean-Michel and Grardel, Nathalie and Touzart, Aurore and Brethon, Benoit and Lapillonne, Hélène and Schmitt, Claudine and Thouvenin, Sandrine and Michel, Gerard and Preudhomme, Claude and Soulier, Jean and Landman-Parker, Judith and Leverger, Guy and Macintyre, Elizabeth and Baruchel, André and Asnafi, Vahid and Aladjidi, Nathalie and Auvrignon, Anne and Baruchel, André and Berger, Claire and Blouin, Pascale and Brethon, Benoit and Chambost, Hervé and Couillault, Gérard and Dalle, Jean-Hugues and Debre, Marianne and Devoldere, Catherine and Dollfus, Catherine and Donadieu, Jean and De Maricourt, Cécile Dumesnil and Edan, Christine and Fasola, Sylvie and Fouyssac, Fanny and Galambrun, Claire and Gandemer, Virginie and Haouy, Stéphanie and Jehanne, Mathilde and Jubert, Charlotte and Kanold, Justyna and Landman-Parker, Judith and Leblanc, Thierry and Lejars, Odile and Le Moine, Philippe and Leverger, Guy and Marie-Cardine, Aude and Margueritte, Geneviève and Mechinaud, Françoise and Michel, Gérard and Oudin, Claire and Oudot, Caroline and Paillard, Catherine and Pautard, Brigitte and Perel, Yves and Petit, Arnaud and Piguet, Christophe and Ray-Lunven, Anne-France and Rialland, Fanny and Schmitt, Claudine and Schneider, Pascale and Stephan, Jean-Louis and Tabone, Marie-Dominique and Thomas, Caroline and Vannier, Jean-Pierre and French Acute Lymphoblastic Leukemi and French Acute Lymphoblastic Leukemia Study Group (FRALLE)
Blood, ISSN 0006-4971, 01/2018, Volume 131, Issue 3, pp. 289 - 300
Risk stratification in childhood T-cell acute lymphoblastic leukemia (T-ALL) is mainly based on minimal residual disease (MRD) quantification. Whether... 
NOTCH1/FBXW7 MUTATIONS | IMPACT | GENE REARRANGEMENTS | PTEN | HEMATOLOGY | MINIMAL RESIDUAL DISEASE | CHILDHOOD | EXPRESSION | FBXW7 MUTATIONS | RISK CLASSIFICATION | CHILDREN | Oncogenes - genetics | Recurrence | Prognosis | Genes, Neoplasm | Humans | Child, Preschool | Infant | Treatment Outcome | Mutation - genetics | Neoplasm, Residual - blood | Neoplasm, Residual - genetics | Disease-Free Survival | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Adolescent | Leukocyte Count | Child | Infant, Newborn
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7. Full Text The MTORC1-mediated autophagy is regulated by the FBXW7-SHOC2-RPTOR axis
by Xie, Chuan-Ming and Sun, Yi
Autophagy, ISSN 1554-8627, 08/2019, Volume 15, Issue 8, pp. 1470 - 1472
MTORC1 is a well-known key regulator of macroautophagy/autophagy. However, the underlying regulatory mechanisms of MTORC1 activity remains elusive. We showed... 
RPTOR | SHOC2 | FBXW7 | Autophagy | MTOR | proliferation and survival | CELL BIOLOGY
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8. Full Text MicroRNA-32 promotes cell proliferation, migration and suppresses apoptosis in breast cancer cells by targeting FBXW7
by Xia, Wei and Zhou, JueYu and Luo, HaiBo and Liu, YunZhou and Peng, CanCan and Zheng, WenLing and Ma, WenLi
Cancer Cell International, ISSN 1475-2867, 01/2017, Volume 17, Issue 1, p. 14
Background: MicroRNAs are a class of small non-coding RNAs that are involved in many important physiological and pathological processes by regulating gene... 
Breast cancer | Proliferation | MiR-32 | FBXW7 | Apoptosis | FBXW7/HCDC4 | METASTASIS | UBIQUITIN LIGASE | STATISTICS | INVASION | ONCOLOGY | GASTRIC-CANCER | COLORECTAL-CANCER | TUMOR-SUPPRESSOR | FBW7 | EXPRESSION
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9. Full Text Long non-coding RNA CASC2 suppresses epithelial-mesenchymal transition of hepatocellular carcinoma cells through CASC2/miR-367/FBXW7 axis
by Wang, Yufeng and Liu, Zhikui and Yao, Bowen and Li, Qing and Wang, Liang and Wang, Cong and Dou, Changwei and Xu, Meng and Liu, Qingguang and Tu, Kangsheng
Molecular Cancer, ISSN 1476-4598, 07/2017, Volume 16, Issue 1, pp. 123 - 15
Background: Recently, it has been reported that long non-coding RNA (lncRNA) cancer susceptibility candidate 2 (CASC2), a novel tumor suppressor, participates... 
MiR-367 | Epithelial-mesenchymal transition | Hepatocellular carcinoma | CASC2 | FBXW7 | Long non-coding RNA | TRANSFORMATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROLIFERATION | miR-367 | LUNG-CANCER | INVASION | ONCOLOGY | SIGNALING PATHWAY | GASTRIC-CANCER | GROWTH ARREST | COLORECTAL-CANCER | TARGETING FBXW7 | MIR-367 PROMOTES | Prognosis | Liver Neoplasms - genetics | Neoplasm Invasiveness | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Male | MicroRNAs - metabolism | RNA, Long Noncoding - genetics | Epithelial-Mesenchymal Transition - genetics | Cell Movement - genetics | Down-Regulation - genetics | Base Sequence | Carcinoma, Hepatocellular - genetics | Carcinoma, Hepatocellular - pathology | Cell Line, Tumor | Female | Liver Neoplasms - pathology | MicroRNAs - genetics | F-Box-WD Repeat-Containing Protein 7 - metabolism | RNA, Long Noncoding - metabolism | Immunohistochemistry | MicroRNA | Analysis | Stem cells | Development and progression | Disease susceptibility | Hepatoma | Metastasis | Health aspects | Biotechnology | Leukocyte migration | Mesenchyme | Lung cancer | Colorectal cancer | Kinases | Tissues | Assaying | Carcinogenesis | Stomach cancer | Cdc4 protein | Western blotting | Metastases | Cell adhesion & migration | Liver cancer | Carcinogens | Cell growth | MiRNA | Biotin | RNA polymerase | Ribonucleic acid--RNA | Polymerase chain reaction | MicroRNAs | Cell lines | Tumor suppressor genes | Non-coding RNA | In vitro methods and tests | Cell migration | Cancer | Apoptosis
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10. Full Text p53 controls CDC7 levels to reinforce G1 cell cycle arrest upon genotoxic stress
by Tudzarova, Slavica and Mulholland, Paul and Mulholland, Paul and Dey, Ayona and Stoeber, Kai and Okorokov, Andrei L and Williams, Gareth H
Cell Cycle, ISSN 1538-4101, 11/2016, Volume 15, Issue 21, pp. 2958 - 2972
DNA replication initiation is a key event in the cell cycle, which is dependent on 2 kinases - CDK2 and CDC7. Here we report a novel mechanism in which p53... 
GSK3β | DNA replication | miRNA-192/215 | cell cycle | DNA damage | Fbxw7β | CDK2 | CDC7 | p21 | protein degradation | p53 | CANCER-CELLS | DNA-REPLICATION CHECKPOINT | PROTEIN | UBIQUITIN LIGASE | PHOSPHORYLATION | miRNA-192 | HUMAN CDC7-RELATED KINASE | TUMOR-SUPPRESSOR NETWORK | CELL BIOLOGY | Fbxw7 | GSK3 | 215 | S-PHASE | INHIBITOR | STRUCTURE PREDICTION | HCT116 Cells | Humans | RNA, Messenger - genetics | Cell Cycle Proteins - metabolism | Protein-Serine-Threonine Kinases - genetics | Tumor Suppressor Protein p53 - metabolism | Ubiquitin-Protein Ligases - metabolism | MicroRNAs - metabolism | RNA, Messenger - metabolism | Glycogen Synthase Kinase 3 beta - metabolism | Down-Regulation - genetics | Feedback, Physiological | Transfection | Proteolysis | Cell Cycle Proteins - genetics | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | G1 Phase Cell Cycle Checkpoints | MicroRNAs - genetics | DNA Damage | Protein-Serine-Threonine Kinases - metabolism
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11. Full Text N6-Isopentenyladenosine Inhibits Colorectal Cancer and Improves Sensitivity to 5-Fluorouracil Targeting FBXW7 Tumor Suppressor
by Fiore, Donatella and Piscopo, Chiara and Proto, Maria and Vasaturo, Michele and Dal Piaz, Fabrizio and Fusco, Bruno and Pagano, Cristina and Laezza, Chiara and Bifulco, Maurizio and Gazzerro, Patrizia
Cancers, ISSN 2072-6694, 09/2019, Volume 11, Issue 10, p. 1456
N6-isopentenyladenosine has been shown to exert potent in vitro antitumor activity on different human cancers, including colorectal cancer. Although some... 
5-fluorouracil | N6-isopentenyladenosine | chemoresistance | mevalonate pathway | FBXW7 | colon cancer
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12. Full Text Meta-analysis of the clinical characteristics and prognostic relevance of NOTCH1 and FBXW7 mutation in T-cell acute lymphoblastic leukemia
by Liu, Rong-Bin and Guo, Jian-Gui and Liu, Tian-Ze and Guo, Cheng-Cheng and Fan, Xin-Xiang and Zhang, Xiao and Hu, Wei-Han and Cai, Xiu-Yu
Oncotarget, ISSN 1949-2553, 2017, Volume 8, Issue 39, pp. 66360 - 66370
The NOTCH1 signaling pathway is crucial for T-cell development, and NOTCH1 and/or FBXW7 mutations are frequently detected in T-cell acute lymphoblastic... 
NOTCH1 | Prognosis | FBXW7 | T-ALL | Meta-analysis | PATHOGENESIS | meta-analysis | prognosis | CELL BIOLOGY
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13. Full Text Overexpression of miR-92a promotes the tumor growth of osteosarcoma by suppressing F-box and WD repeat-containing protein 7
by Jiang, Xuesheng and Li, Xiongfeng and Li, Jianyou and Wu, Fengfeng and Gao, Hongliang and Wang, Huajun and Wang, Guorong and Zheng, Hua and Chen, Chao
Gene, ISSN 0378-1119, 03/2017, Volume 606, pp. 10 - 16
MicroRNAs (miRNAs) have been reported to be critical players in osteosarcoma (OS). Among numerous cancer-related miRNAs, the expression level of miR-92a and... 
Cell cycle progression | Proliferation | Osteosarcoma | FBXW7 | miR-92a | Apoptosis | CELLS | METASTASIS | HEPATOCELLULAR-CARCINOMA | GENETICS & HEREDITY | TARGETING FBXW7 | HUMAN CANCERS | MICRORNA | F-Box-WD Repeat-Containing Protein 7 | F-Box Proteins - metabolism | Humans | Cell Cycle Proteins - metabolism | Gene Expression Regulation, Neoplastic | Ubiquitin-Protein Ligases - metabolism | MicroRNAs - metabolism | Animals | Mice, Nude | Bone and Bones - metabolism | Cell Line, Tumor | Mice | Osteosarcoma - genetics | Osteosarcoma - pathology | Development and progression | Tumors
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14. Full Text SCFFBXW7/GSK3 beta-Mediated GFI1 Degradation Suppresses Proliferation of Gastric Cancer Cells
by Kuai, XL and Li, L and Chen, R and Wang, KJJ and Chen, M and Cui, BH and Zhang, YX and Li, JQ and Zhu, HW and Zhou, H and Huang, JF and Qin, J and Wang, ZW and Wei, WY and Gao, DM
CANCER RESEARCH, ISSN 0008-5472, 09/2019, Volume 79, Issue 17, pp. 4387 - 4398
Gastric cancer is the third leading cause of cancer-related death worldwide. The regulatory mechanisms underlying gastric cancer cell proliferation are largely... 
APOPTOSIS | ONCOLOGY | FBXW7 | STATISTICS | PROGNOSIS | GROWTH | GENES | C-MYC | TUMOR-SUPPRESSOR | EXPRESSION | FBW7 UBIQUITIN LIGASE
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15. Full Text Tumor suppressor Fbxw7 antagonizes WNT signaling by targeting β-catenin for degradation in pancreatic cancer
by Jiang, Jian-xin and Sun, Cheng-yi and Tian, She and Yu, Chao and Chen, Mei-yuan and Zhang, Hao
Tumor Biology, ISSN 1010-4283, 10/2016, Volume 37, Issue 10, pp. 13893 - 13902
Pancreatic cancer is one of the deadliest solid malignancies associated with aberrant Wnt signaling activation. Fbxw7 mutations have been implicated in the... 
Degradation | Biomedicine | Fbxw7 | Wnt/β-catenin | Interaction | Pancreatic cancer | Cancer Research | FBXW7/HCDC4 | C-MYC | UBIQUITIN LIGASE FBXW7 | INACTIVATION | GENE | ONCOLOGY | GASTRIC-CANCER | Wnt/beta-catenin | MOLECULAR PATHOGENESIS | DIFFERENTIATION | FBW7 | EXPRESSION | F-Box-WD Repeat-Containing Protein 7 | Cell Proliferation | Immunoprecipitation | Pancreatic Neoplasms - metabolism | Humans | Gene Expression Regulation, Neoplastic | Ubiquitin - metabolism | Wnt Proteins - metabolism | Wnt Proteins - genetics | Proteolysis | Biomarkers, Tumor - metabolism | Cell Cycle Proteins - genetics | Female | Tumor Cells, Cultured | Real-Time Polymerase Chain Reaction | F-Box Proteins - metabolism | Pancreatic Neoplasms - pathology | RNA, Messenger - genetics | Cell Cycle Proteins - metabolism | Ubiquitin-Protein Ligases - metabolism | Pancreatic Neoplasms - genetics | Reverse Transcriptase Polymerase Chain Reaction | beta Catenin - metabolism | Blotting, Western | beta Catenin - genetics | Xenograft Model Antitumor Assays | Animals | Mice, Nude | Biomarkers, Tumor - genetics | Mice | Mice, Inbred BALB C | Ubiquitin-Protein Ligases - genetics | F-Box Proteins - genetics | Apoptosis
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16. Full Text Increased incidence of FBXW7 and POLE proofreading domain mutations in young adult colorectal cancers
by Kothari, Nishi and Teer, Jamie K and Abbott, Andrea M and Srikumar, Thejal and Zhang, Yonghong and Yoder, Sean J and Brohl, Andrew S and Kim, Richard D and Reed, Damon R and Shibata, David
Cancer, ISSN 0008-543X, 09/2016, Volume 122, Issue 18, pp. 2828 - 2835
BACKGROUND The incidence and outcomes of patients with colorectal cancer (CRC) varies by age. Younger patients tend to have sporadic cancers that are not... 
adolescent and young adults | colorectal cancer | biomarkers | F‐box and WD repeat‐containing protein 7 (FBXW7) | Adolescent and young adults | Biomarkers | F-box and WD repeat-containing protein 7 (FBXW7) | Colorectal cancer | UNITED-STATES | SURVIVAL | STATISTICS | POLYMERASE | DISCOVERY | ADOLESCENT | BREAST-CANCER | IMPACT | GENOMICS | ONCOLOGY | ACUTE LYMPHOBLASTIC-LEUKEMIA | F-Box-WD Repeat-Containing Protein 7 | Colorectal Neoplasms - enzymology | Age Factors | F-Box Proteins - metabolism | Colorectal Neoplasms - genetics | Humans | Middle Aged | Cell Cycle Proteins - metabolism | Ubiquitin-Protein Ligases - metabolism | Male | DNA Polymerase II - metabolism | Incidence | Poly-ADP-Ribose Binding Proteins | Aged, 80 and over | Cell Cycle Proteins - genetics | Female | Aged | Retrospective Studies | Mutation | Colorectal Neoplasms - pathology | Ubiquitin-Protein Ligases - genetics | DNA Polymerase II - genetics | F-Box Proteins - genetics | Cohort Studies | Diagnosis | Demographic aspects | Patient outcomes | AYA | iomarkers
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17. Full Text NF-kappa B p65 Overexpression Promotes Bladder Cancer Cell Migration via FBW7-Mediated Degradation of RhoGDIa Protein
by Zhu, JL and Li, Y and Chen, CY and Ma, JG and Sun, WR and Tian, ZX and Li, JX and Xu, JH and Liu, CS and Zhang, DY and Huang, CS and Huang, HS
NEOPLASIA, ISSN 1476-5586, 09/2017, Volume 19, Issue 9, pp. 672 - 683
BACKGROUND: Since invasive bladder cancer (BC) is one of the most lethal urological malignant tumors worldwide, understanding the molecular mechanisms that... 
BREAST-CANCER | ACTIVATION | INVASION | METASTASIS | ONCOLOGY | FBXW7 | PHOSPHORYLATION | TUMOR-SUPPRESSOR | RHO-GTPASES | FBW7 UBIQUITIN LIGASE | PTEN EXPRESSION
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