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Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 12/2013, Volume 369, Issue 24, pp. 2313 - 2323
Journal Article
Blood, ISSN 0006-4971, 03/2012, Volume 119, Issue 13, pp. 3031 - 3037
Journal Article
EMBO Molecular Medicine, ISSN 1757-4676, 10/2012, Volume 4, Issue 10, pp. 1015 - 1028
Journal Article
Journal of Thrombosis and Haemostasis, ISSN 1538-7933, 01/2013, Volume 11, Issue 1, pp. 132 - 141
Background: Hemophilia A results from a deficiency in factor VIII activity. Current treatment regimens require frequent dosing, owing to the short half‐life of... 
Fc fusion | hemophilia A | long‐acting | rFVIIIFc | Factor VIII | RFVIIIFc | Long-acting | Hemophilia A | DOMAIN | HEMOPHILIA-A | FACTOR-IX | PROLONGED ACTIVITY | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | long-acting | Recombinant Fusion Proteins - pharmacology | Immunoglobulin Fc Fragments - metabolism | Factor VIII - pharmacokinetics | Humans | Half-Life | Male | Structure-Activity Relationship | Coagulants - chemistry | Neoplasm Proteins - metabolism | Cysteine Endopeptidases - metabolism | Coagulants - pharmacology | Mass Spectrometry | Cloning, Molecular | Protein Engineering | Coagulants - pharmacokinetics | Protein Stability | Binding Sites | Disease Models, Animal | von Willebrand Factor - metabolism | Amino Acid Sequence | Thrombelastography | Factor VIII - chemistry | Factor VIII - genetics | Immunoglobulin Fc Fragments - chemistry | Peptide Mapping - methods | Hemophilia A - blood | Animals | Blood Coagulation - drug effects | Partial Thromboplastin Time | Recombinant Fusion Proteins - pharmacokinetics | Factor VIII - pharmacology | Protein Conformation | Mice | Protein C - metabolism | Hemophilia A - drug therapy | Immunoglobulin Fc Fragments - genetics | Proteins | Blood coagulation factor VIII | Medical examination | Analysis | Immunoglobulin G | Questions and answers | Hemophilia | Thrombin | Liquid chromatography | Chemical properties | Mass spectrometry | Blood | Coagulation
Journal Article
Blood, ISSN 0006-4971, 03/2010, Volume 115, Issue 10, pp. 2057 - 2064
Journal Article
BLOOD, ISSN 0006-4971, 03/2012, Volume 119, Issue 13, pp. 3024 - 3030
Journal Article
Applied Microbiology and Biotechnology, ISSN 0175-7598, 6/2019, Volume 103, Issue 12, pp. 4753 - 4765
Journal Article
Nature Medicine, ISSN 1078-8956, 04/2005, Volume 11, Issue 43, pp. 446 - 449
Journal Article
Journal of Thrombosis and Haemostasis, ISSN 1538-7933, 06/2015, Volume 13, Issue 6, pp. 967 - 977
Summary Background Prophylactic factor replacement, which prevents hemarthroses and thereby reduces the musculoskeletal disease burden in children with... 
hemophilia A | recombinant fusion proteins | coagulation factor VIII | children | prophylaxis | Children | Coagulation factor VIII | Recombinant fusion proteins | Hemophilia A | Prophylaxis | Recombinant Fusion Proteins - immunology | Factor VIII - immunology | Hemarthrosis - diagnosis | Age Factors | Recombinant Fusion Proteins - adverse effects | Factor VIII - pharmacokinetics | Humans | Child, Preschool | Half-Life | Male | Immunoglobulin Fc Fragments - administration & dosage | North America | Hemarthrosis - blood | Immunoglobulin Fc Fragments - immunology | China | Coagulants - administration & dosage | Factor VIII - adverse effects | Female | Hemophilia A - prevention & control | Coagulants - pharmacokinetics | Hemophilia A - diagnosis | Child | Immunoglobulin Fc Fragments - adverse effects | Recombinant Fusion Proteins - administration & dosage | Severity of Illness Index | Drug Administration Schedule | Europe | Risk Factors | Treatment Outcome | Hemophilia A - blood | Hemarthrosis - drug therapy | Recombinant Fusion Proteins - pharmacokinetics | Factor VIII - administration & dosage | South Africa | Infusions, Intravenous | Australia | Coagulants - adverse effects | Coagulants - immunology | Hemarthrosis - prevention & control | Hemophilia A - drug therapy | Antibodies, Neutralizing - blood | Prevention | Proteins | Care and treatment | Blood coagulation factor VIII | Hemophilia
Journal Article
Journal of Thrombosis and Haemostasis, ISSN 1538-7933, 01/2019, Volume 17, Issue 1, pp. 138 - 148
Summary Essentials Performance of the one‐stage clotting (OSC) assay varies with the clotting activator used. Recombinant FIX‐albumin fusion protein (rIX‐FP)... 
multicenter study | factor IX | activated partial thromboplastin time | blood coagulation tests | hemophilia B | DISCREPANCIES | factor IX | DIAGNOSIS | hemophilia B | PERIPHERAL VASCULAR DISEASE | CHROMOGENIC ASSAYS | MODIFIED FACTOR-VIII | RIX-FP | HEMATOLOGY | Thromboplastin | Coagulation factors | Proteins | Fc receptors | Coagulation factor IX | Laboratories | Actin | Hemophilia | Albumin | Fusion protein | Clotting | Kaolin
Journal Article