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The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 2011, Volume 128, Issue 3, pp. 567 - 573.e1
Proof-of-concept studies with omalizumab in patients with chronic idiopathic urticaria (CIU) have shown significant decreases in mean urticaria activity scores... 
hive | itch | H 1-antihistamine | urticaria activity score | omalizumab | dose ranging | Chronic idiopathic urticaria | chronic spontaneous urticaria | AUTOANTIBODIES | DEFINITION | DIAGNOSIS | FC-EPSILON-RI | CLASSIFICATION | IMMUNOLOGY | CIU | GUIDELINE | ALLERGY | AUTOIMMUNE URTICARIA | QUALITY-OF-LIFE | H-1-antihistamine | EXPRESSION
Journal Article
Cell Host & Microbe, ISSN 1931-3128, 11/2013, Volume 14, Issue 5, pp. 559 - 570
Journal Article
BLOOD, ISSN 0006-4971, 04/2008, Volume 111, Issue 7, pp. 3665 - 3674
Inflammatory responses by mast cells are characterized by massive exocytosis of prestored granular mediators followed by cytokine/chemokine release. The... 
EFFECTOR | LYSOSOMES | FC-EPSILON-RI | IGE | REGULATED EXOCYTOSIS | DEGRANULATION | TNF-ALPHA | RELEASE | HEMATOLOGY | SECRETORY GRANULES | SNARE
Journal Article
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 2004, Volume 114, Issue 3, pp. 527 - 530
By design, omalizumab binds free IgE in the circulation and prevents its attachment to the surface of mast cells and basophils, thereby preventing them from... 
Mast cells | FcεRI | omalizumab | basophils | ALLERGY | Fc epsilon RI | IN-VIVO | DOWN-REGULATION | IMMUNOLOGY | mast cells | ANTI-IGE ANTIBODY
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2013, Volume 132, Issue 1, pp. 101 - 109
Journal Article
Rheumatology, ISSN 1462-0324, 04/2019, Volume 58, Issue 4, pp. 617 - 627
Abstract Objectives Synovial mast cells contain IL-17A, a key driver of tissue inflammation in SpA. A recent in vitro study showed that tissue-derived mast... 
IL-17A | mast cells | anti-IL-17A therapy (secukinumab) | FC-EPSILON-RI | SECUKINUMAB | RELEVANCE | RELEASE | RHEUMATOLOGY | INHIBITOR | EXPRESSION | IL-6
Journal Article
by Roy, S and Ganguly, A and Haque, M and Ali, H
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 02/2019, Volume 202, Issue 4, pp. 1229 - 1238
AG-30/5C is an angiogenic host defense peptide that activates human mast cells (MC) via an unknown mechanism. Using short hairpin RNA-silenced human MC line... 
MEDIATED INNATE IMMUNITY | ACTIVATION | FC-EPSILON-RI | GENE X2 | DESENSITIZATION | COUPLED RECEPTOR | ANTIMICROBIAL PEPTIDE | TRAFFICKING | BACTERIAL | TRYPTASE | IMMUNOLOGY
Journal Article
ARCHIVOS DE BRONCONEUMOLOGIA, ISSN 0300-2896, 07/2018, Volume 54, Issue 7, pp. 393 - 394
Journal Article
by Sun, ZT and Liu, Q and Qu, G and Feng, Y and Reetz, MT
CHEMICAL REVIEWS, ISSN 0009-2665, 02/2019, Volume 119, Issue 3, pp. 1626 - 1665
The term B-factor, sometimes called the Debye Waller factor, temperature factor, or atomic displacement parameter, is used in protein crystallography to... 
ELASTIC NETWORK MODEL | CONFORMATIONAL ENSEMBLES | FC-EPSILON-RI | LABORATORY EVOLUTION | CRYSTAL-STRUCTURE | ITERATIVE SATURATION MUTAGENESIS | X-RAY | MOLECULAR-DYNAMICS SIMULATIONS | BACILLUS-SUBTILIS LIPASE | DIRECTED EVOLUTION | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Nature, ISSN 0028-0836, 10/2004, Volume 431, Issue 7011, pp. 1007 - 1011
Inflammatory substances released by mast cells induce and maintain the allergic response. Mast cell differentiation and activation are regulated, respectively,... 
FC-EPSILON-RI | MAST-CELL ACTIVATION | P110 DELTA | LEUKOCYTES | PHOSPHATIDYLINOSITOL 3-KINASE | MULTIDISCIPLINARY SCIENCES | KIT | HYPOGLYCEMIA | P85-ALPHA SUBUNIT | INCREASED INSULIN SENSITIVITY | MICE LACKING
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 12/2016, Volume 7
Asthma has multiple features, including airway hyperreactivity, inflammation and remodelling. The TNF superfamily member TNFSF14 ( LIGHT), via interactions... 
FC-EPSILON-RI | ACTIVATED T-CELLS | IGE | MULTIDISCIPLINARY SCIENCES | MOUSE | DEGRANULATION | RECEPTOR | COSTIMULATION | MAST-CELL | HYPERRESPONSIVENESS | ANAPHYLAXIS
Journal Article
MOLECULAR & CELLULAR PROTEOMICS, ISSN 1535-9476, 05/2015, Volume 14, Issue 5, pp. 1265 - 1274
Genome-wide association studies to identify loci responsible for platelet function and cardiovascular disease susceptibility have repeatedly identified... 
INTERACTION NETWORK | OMALIZUMAB | PLATFORM | FC-EPSILON-RI | ALLERGY | IGE | BIOCHEMICAL RESEARCH METHODS | LIBRARY | CELL-SURFACE | EXPRESSION | REVEALS
Journal Article
CANCER RESEARCH, ISSN 0008-5472, 03/2017, Volume 77, Issue 5, pp. 1127 - 1141
IgE antibodies are key mediators of antiparasitic immune responses, but their potential for cancer treatment via antibody-dependent cell-mediated cytotoxicity... 
CELL LUNG-CANCER | ANTIBODY-BASED THERAPEUTICS | IN-VITRO | FC-EPSILON-RI | SOLID TUMORS | VIVO | ONCOLOGY | IMMUNOTHERAPY | OVARIAN-CANCER | FOLATE-BINDING-PROTEIN | PROGRESSION
Journal Article